MFAP2 (microfibril associated protein 2) - Rat Genome Database

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Gene: MFAP2 (microfibril associated protein 2) Sus scrofa
Analyze
Symbol: MFAP2
Name: microfibril associated protein 2
RGD ID: 13876306
Description: ENCODES a protein that exhibits fibrinogen binding (ortholog); fibronectin binding (ortholog); INVOLVED IN platelet formation (ortholog); positive regulation of cold-induced thermogenesis (ortholog); PARTICIPATES IN Notch signaling pathway; ASSOCIATED WITH chromosome 1p36 deletion syndrome (ortholog); genetic disease (ortholog); ovarian cyst (ortholog); FOUND IN microfibril (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: microfibrillar associated protein 2; microfibrillar-associated protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl675,607,521 - 75,615,641 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1675,607,515 - 75,615,680 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2669,920,815 - 69,928,972 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:15679890   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
MFAP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl675,607,521 - 75,615,641 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1675,607,515 - 75,615,680 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2669,920,815 - 69,928,972 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MFAP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38116,974,502 - 16,981,583 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl116,974,502 - 16,980,632 (-)EnsemblGRCh38hg38GRCh38
GRCh37117,300,997 - 17,308,078 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36117,173,584 - 17,180,668 (-)NCBINCBI36Build 36hg18NCBI36
Celera115,623,335 - 15,630,419 (-)NCBICelera
Cytogenetic Map1p36.13NCBI
HuRef115,545,079 - 15,552,161 (-)NCBIHuRef
CHM1_1117,409,311 - 17,416,419 (-)NCBICHM1_1
T2T-CHM13v2.0116,784,929 - 16,792,008 (-)NCBIT2T-CHM13v2.0
Mfap2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394140,737,735 - 140,743,284 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4140,737,729 - 140,743,295 (+)EnsemblGRCm39 Ensembl
GRCm384141,010,424 - 141,015,976 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4141,010,418 - 141,015,984 (+)EnsemblGRCm38mm10GRCm38
MGSCv374140,566,339 - 140,571,899 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364140,282,779 - 140,288,049 (+)NCBIMGSCv36mm8
Celera4142,810,410 - 142,815,979 (+)NCBICelera
Cytogenetic Map4D3NCBI
cM Map473.31NCBI
Mfap2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85158,595,121 - 158,603,283 (+)NCBIGRCr8
mRatBN7.25153,312,068 - 153,320,266 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5153,314,711 - 153,320,259 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5156,003,158 - 156,008,692 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05157,776,429 - 157,781,963 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05157,765,613 - 157,771,147 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05159,534,202 - 159,539,750 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5159,534,202 - 159,539,750 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05163,246,454 - 163,252,003 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45159,868,933 - 159,874,481 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15159,879,913 - 159,884,266 (+)NCBI
Celera5151,679,623 - 151,685,290 (+)NCBICelera
Cytogenetic Map5q36NCBI
Mfap2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555271,826,528 - 1,832,052 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555271,826,528 - 1,832,058 (+)NCBIChiLan1.0ChiLan1.0
MFAP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21210,144,804 - 210,155,917 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11209,268,574 - 209,274,736 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0115,918,209 - 15,924,388 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1 Ensembl116,975,544 - 17,006,022 (-)Ensemblpanpan1.1panPan2
MFAP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1281,217,197 - 81,223,726 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl281,220,431 - 81,224,243 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha277,753,979 - 77,760,380 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0281,863,358 - 81,869,768 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl281,866,473 - 81,869,582 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1278,616,367 - 78,622,775 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0279,633,264 - 79,639,634 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0280,701,361 - 80,707,780 (+)NCBIUU_Cfam_GSD_1.0
Mfap2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505838,135,115 - 38,139,943 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364743,956,095 - 3,963,253 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364743,959,499 - 3,963,326 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MFAP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120115,610,590 - 115,616,983 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20115,610,808 - 115,617,506 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666033503,565 - 510,642 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mfap2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247642,606,138 - 2,611,732 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247642,606,089 - 2,611,738 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in MFAP2
219 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium
Low 8 4 3 5 2 7 2 3 1
Below cutoff 2 10 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000003865   ⟹   ENSSSCP00000003777
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl675,607,521 - 75,615,641 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000058044   ⟹   ENSSSCP00000040757
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl675,607,521 - 75,611,110 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000074743   ⟹   ENSSSCP00000066340
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl675,607,521 - 75,615,641 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000104499   ⟹   ENSSSCP00000078628
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl675,607,521 - 75,611,110 (-)Ensembl
RefSeq Acc Id: XM_003127644   ⟹   XP_003127692
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1675,607,515 - 75,615,671 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005665047   ⟹   XP_005665104
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1675,607,515 - 75,615,680 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_005665104   ⟸   XM_005665047
- Peptide Label: isoform X2
- UniProtKB: A0A8D1LRE5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003127692   ⟸   XM_003127644
- Peptide Label: isoform X1
- UniProtKB: F1SUS0 (UniProtKB/TrEMBL),   A0A4X1W8I2 (UniProtKB/TrEMBL),   A0A8D1LRE5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000040757   ⟸   ENSSSCT00000058044
RefSeq Acc Id: ENSSSCP00000066340   ⟸   ENSSSCT00000074743
RefSeq Acc Id: ENSSSCP00000003777   ⟸   ENSSSCT00000003865
RefSeq Acc Id: ENSSSCP00000078628   ⟸   ENSSSCT00000104499
Protein Domains
ShKT


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000003479 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00025004209 UniProtKB/TrEMBL
  ENSSSCG00030025617 UniProtKB/TrEMBL
  ENSSSCG00035029493 UniProtKB/TrEMBL
  ENSSSCG00040043587 UniProtKB/TrEMBL
  ENSSSCG00045029530 UniProtKB/TrEMBL
  ENSSSCG00050021284 UniProtKB/TrEMBL
  ENSSSCG00055010756 UniProtKB/TrEMBL
  ENSSSCG00060020614 UniProtKB/TrEMBL
  ENSSSCG00065073450 UniProtKB/TrEMBL
  ENSSSCG00070029281 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000003865 ENTREZGENE
  ENSSSCT00000003865.5 UniProtKB/TrEMBL
  ENSSSCT00000058044.3 UniProtKB/TrEMBL
  ENSSSCT00000074743.2 UniProtKB/TrEMBL
  ENSSSCT00000104499.1 UniProtKB/TrEMBL
  ENSSSCT00025005587.1 UniProtKB/TrEMBL
  ENSSSCT00030035779.1 UniProtKB/TrEMBL
  ENSSSCT00030035789.1 UniProtKB/TrEMBL
  ENSSSCT00030035809.1 UniProtKB/TrEMBL
  ENSSSCT00030035829.1 UniProtKB/TrEMBL
  ENSSSCT00030035848.1 UniProtKB/TrEMBL
  ENSSSCT00030035858.1 UniProtKB/TrEMBL
  ENSSSCT00035039083.1 UniProtKB/TrEMBL
  ENSSSCT00035039099.1 UniProtKB/TrEMBL
  ENSSSCT00035039104.1 UniProtKB/TrEMBL
  ENSSSCT00040058429.1 UniProtKB/TrEMBL
  ENSSSCT00045050479.1 UniProtKB/TrEMBL
  ENSSSCT00045050599.1 UniProtKB/TrEMBL
  ENSSSCT00050028692.1 UniProtKB/TrEMBL
  ENSSSCT00050028702.1 UniProtKB/TrEMBL
  ENSSSCT00055021129.1 UniProtKB/TrEMBL
  ENSSSCT00055021184.1 UniProtKB/TrEMBL
  ENSSSCT00060027928.1 UniProtKB/TrEMBL
  ENSSSCT00065101227.1 UniProtKB/TrEMBL
  ENSSSCT00070058788.1 UniProtKB/TrEMBL
  ENSSSCT00070058791.1 UniProtKB/TrEMBL
  ENSSSCT00070058793.1 UniProtKB/TrEMBL
  ENSSSCT00070058795.1 UniProtKB/TrEMBL
InterPro MAGP UniProtKB/TrEMBL
  ShKT_dom UniProtKB/TrEMBL
KEGG Report ssc:100523794 UniProtKB/TrEMBL
NCBI Gene MFAP2 ENTREZGENE
PANTHER MICROFIBRILLAR-ASSOCIATED PROTEIN 2 UniProtKB/TrEMBL
  PTHR16485 UniProtKB/TrEMBL
Pfam MAGP UniProtKB/TrEMBL
PROSITE SHKT UniProtKB/TrEMBL
UniProt A0A287AAB8_PIG UniProtKB/TrEMBL
  A0A4X1W1F2_PIG UniProtKB/TrEMBL
  A0A4X1W7J5_PIG UniProtKB/TrEMBL
  A0A4X1W8I2 ENTREZGENE, UniProtKB/TrEMBL
  A0A5G2QNS3_PIG UniProtKB/TrEMBL
  A0A8D0W506_PIG UniProtKB/TrEMBL
  A0A8D0W5L4_PIG UniProtKB/TrEMBL
  A0A8D0W5M5_PIG UniProtKB/TrEMBL
  A0A8D0W8W1_PIG UniProtKB/TrEMBL
  A0A8D0ZHA7_PIG UniProtKB/TrEMBL
  A0A8D1C452_PIG UniProtKB/TrEMBL
  A0A8D1CRJ6_PIG UniProtKB/TrEMBL
  A0A8D1LRE5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8W4FIB5_PIG UniProtKB/TrEMBL
  F1SUS0 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:90173 ENTREZGENE