AMOTL1 (angiomotin like 1) - Rat Genome Database

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Gene: AMOTL1 (angiomotin like 1) Sus scrofa
Analyze
Symbol: AMOTL1
Name: angiomotin like 1
RGD ID: 13876204
Description: ENCODES a protein that exhibits identical protein binding (inferred); INVOLVED IN blood vessel endothelial cell migration (ortholog); establishment of cell polarity involved in ameboidal cell migration (ortholog); establishment of epithelial cell polarity (ortholog); ASSOCIATED WITH ataxia telangiectasia (ortholog); Disease Progression (ortholog); genetic disease (ortholog); FOUND IN apical plasma membrane (ortholog); COP9 signalosome (ortholog); lamellipodium (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: angiomotin-like protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl926,864,312 - 26,973,552 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1926,811,872 - 26,978,107 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2930,564,601 - 30,732,223 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
AMOTL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl926,864,312 - 26,973,552 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1926,811,872 - 26,978,107 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2930,564,601 - 30,732,223 (+)NCBISscrofa10.2Sscrofa10.2susScr3
AMOTL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381194,706,460 - 94,876,748 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1194,706,431 - 94,876,748 (+)EnsemblGRCh38hg38GRCh38
GRCh371194,501,522 - 94,609,913 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361194,141,156 - 94,249,566 (+)NCBINCBI36Build 36hg18NCBI36
Build 341194,141,184 - 94,251,003NCBI
Celera1191,789,295 - 91,897,678 (+)NCBICelera
Cytogenetic Map11q21NCBI
HuRef1190,566,554 - 90,674,939 (+)NCBIHuRef
CHM1_11194,384,453 - 94,492,924 (+)NCBICHM1_1
T2T-CHM13v2.01194,713,440 - 94,883,739 (+)NCBIT2T-CHM13v2.0
Amotl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39914,453,262 - 14,574,408 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl914,453,262 - 14,556,352 (-)EnsemblGRCm39 Ensembl
GRCm38914,541,966 - 14,662,974 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl914,541,966 - 14,645,056 (-)EnsemblGRCm38mm10GRCm38
MGSCv37914,346,410 - 14,419,444 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36914,292,363 - 14,365,393 (-)NCBIMGSCv36mm8
Celera911,822,704 - 11,895,738 (-)NCBICelera
Cytogenetic Map9A2NCBI
cM Map94.12NCBI
Amotl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8819,630,139 - 19,749,027 (-)NCBIGRCr8
mRatBN7.2811,348,651 - 11,467,564 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl811,353,674 - 11,467,573 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0813,037,265 - 13,157,701 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl813,042,641 - 13,109,487 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0812,982,311 - 13,099,471 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4811,296,503 - 11,392,970 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1811,296,994 - 11,394,851 (-)NCBI
Celera812,842,189 - 12,874,526 (-)NCBICelera
Cytogenetic Map8q12NCBI
Amotl1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955605113,570 - 245,932 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955605113,570 - 275,921 (-)NCBIChiLan1.0ChiLan1.0
AMOTL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2995,584,025 - 95,730,714 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11196,686,982 - 96,822,188 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01189,743,625 - 89,890,334 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11193,268,860 - 93,413,197 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1193,278,464 - 93,413,197 (+)Ensemblpanpan1.1panPan2
AMOTL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1216,109,600 - 6,280,025 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl216,109,683 - 6,256,060 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha216,120,727 - 6,290,996 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0216,295,578 - 6,460,498 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl216,291,262 - 6,437,052 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1216,077,936 - 6,202,162 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0216,140,874 - 6,310,947 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0216,188,761 - 6,359,356 (-)NCBIUU_Cfam_GSD_1.0
Amotl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494779,605,892 - 79,727,013 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936674156,552 - 223,685 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936674163,889 - 285,523 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AMOTL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1185,927,458 - 86,080,239 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl185,996,908 - 86,079,857 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604339,700,123 - 39,839,962 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Amotl1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473539,435,338 - 39,539,826 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473539,393,567 - 39,544,266 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in AMOTL1
7976 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 2 3 2 7 2
Low 7 4 5 16 2 1 1
Below cutoff 1 2

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005667237 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005667238 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005667239 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013979291 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013979294 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013979295 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021062681 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021062682 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021062683 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021062684 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021062685 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021062687 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AEMK02000070 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK397869 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CU571278 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CU914369 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GFLN01120393 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSSSCT00000041933   ⟹   ENSSSCP00000034121
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl926,864,312 - 26,973,552 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000057463   ⟹   ENSSSCP00000034966
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl926,812,004 - 26,978,107 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000066175   ⟹   ENSSSCP00000052243
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl926,864,326 - 26,973,552 (+)Ensembl
RefSeq Acc Id: XM_005667237   ⟹   XP_005667294
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1926,811,872 - 26,978,107 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005667238   ⟹   XP_005667295
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1926,864,319 - 26,978,107 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005667239   ⟹   XP_005667296
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1926,864,316 - 26,978,107 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013979291   ⟹   XP_013834745
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1926,812,840 - 26,978,107 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013979294   ⟹   XP_013834748
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1926,811,895 - 26,978,107 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013979295   ⟹   XP_013834749
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1926,864,579 - 26,978,107 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021062681   ⟹   XP_020918340
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1926,811,895 - 26,978,107 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021062682   ⟹   XP_020918341
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1926,812,854 - 26,978,107 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021062683   ⟹   XP_020918342
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1926,811,895 - 26,978,107 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021062684   ⟹   XP_020918343
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1926,811,901 - 26,978,107 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021062685   ⟹   XP_020918344
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1926,864,053 - 26,978,107 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021062687   ⟹   XP_020918346
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1926,866,154 - 26,978,107 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_005667294   ⟸   XM_005667237
- Peptide Label: isoform X2
- UniProtKB: A0A8D1P5Q3 (UniProtKB/TrEMBL),   F1STJ4 (UniProtKB/TrEMBL),   A0A8D0Y507 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020918340   ⟸   XM_021062681
- Peptide Label: isoform X1
- UniProtKB: A0A8D1CSK2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020918342   ⟸   XM_021062683
- Peptide Label: isoform X4
- UniProtKB: A0A8D1PDD4 (UniProtKB/TrEMBL),   A0A8D0Y3J6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013834748   ⟸   XM_013979294
- Peptide Label: isoform X5
- UniProtKB: A0A8D1TKM2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020918343   ⟸   XM_021062684
- Peptide Label: isoform X7
- UniProtKB: A0A8D0MSF2 (UniProtKB/TrEMBL),   A0A8D1WTM8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013834745   ⟸   XM_013979291
- Peptide Label: isoform X1
- UniProtKB: A0A8D1CSK2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020918341   ⟸   XM_021062682
- Peptide Label: isoform X2
- UniProtKB: A0A8D1P5Q3 (UniProtKB/TrEMBL),   F1STJ4 (UniProtKB/TrEMBL),   A0A8D0Y507 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020918344   ⟸   XM_021062685
- Peptide Label: isoform X7
- UniProtKB: A0A8D0MSF2 (UniProtKB/TrEMBL),   A0A8D1WTM8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005667296   ⟸   XM_005667239
- Peptide Label: isoform X6
- UniProtKB: A0A8D0MRX9 (UniProtKB/TrEMBL),   A0A286ZR74 (UniProtKB/TrEMBL),   A0A8D1CGU3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005667295   ⟸   XM_005667238
- Peptide Label: isoform X3
- UniProtKB: A0A8D0MSJ7 (UniProtKB/TrEMBL),   A0A287B809 (UniProtKB/TrEMBL),   A0A8D1WSQ3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013834749   ⟸   XM_013979295
- Peptide Label: isoform X7
- UniProtKB: A0A8D0MSF2 (UniProtKB/TrEMBL),   A0A8D1WTM8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020918346   ⟸   XM_021062687
- Peptide Label: isoform X7
- UniProtKB: A0A8D0MSF2 (UniProtKB/TrEMBL),   A0A8D1WTM8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000034121   ⟸   ENSSSCT00000041933
RefSeq Acc Id: ENSSSCP00000052243   ⟸   ENSSSCT00000066175
RefSeq Acc Id: ENSSSCP00000034966   ⟸   ENSSSCT00000057463
Protein Domains
Angiomotin C-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000014960 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015015309 UniProtKB/TrEMBL
  ENSSSCG00025043407 UniProtKB/TrEMBL
  ENSSSCG00030068055 UniProtKB/TrEMBL
  ENSSSCG00035032526 UniProtKB/TrEMBL
  ENSSSCG00050058855 UniProtKB/TrEMBL
  ENSSSCG00055001027 UniProtKB/TrEMBL
  ENSSSCG00060074439 UniProtKB/TrEMBL
  ENSSSCG00065048942 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000041933 ENTREZGENE
  ENSSSCT00000041933.3 UniProtKB/TrEMBL
  ENSSSCT00000066175 ENTREZGENE
  ENSSSCT00000066175.3 UniProtKB/TrEMBL
  ENSSSCT00015020254.1 UniProtKB/TrEMBL
  ENSSSCT00015020298.1 UniProtKB/TrEMBL
  ENSSSCT00015020358.1 UniProtKB/TrEMBL
  ENSSSCT00025058857.1 UniProtKB/TrEMBL
  ENSSSCT00025059318.1 UniProtKB/TrEMBL
  ENSSSCT00025059576.1 UniProtKB/TrEMBL
  ENSSSCT00030095171.1 UniProtKB/TrEMBL
  ENSSSCT00030095205.1 UniProtKB/TrEMBL
  ENSSSCT00030095242.1 UniProtKB/TrEMBL
  ENSSSCT00030095275.1 UniProtKB/TrEMBL
  ENSSSCT00035043079.1 UniProtKB/TrEMBL
  ENSSSCT00035043086.1 UniProtKB/TrEMBL
  ENSSSCT00035043096.1 UniProtKB/TrEMBL
  ENSSSCT00035043098.1 UniProtKB/TrEMBL
  ENSSSCT00035043105.1 UniProtKB/TrEMBL
  ENSSSCT00050080198.1 UniProtKB/TrEMBL
  ENSSSCT00055001805.1 UniProtKB/TrEMBL
  ENSSSCT00055001810.1 UniProtKB/TrEMBL
  ENSSSCT00055001835.1 UniProtKB/TrEMBL
  ENSSSCT00055001846.1 UniProtKB/TrEMBL
  ENSSSCT00060101773.1 UniProtKB/TrEMBL
  ENSSSCT00060101798.1 UniProtKB/TrEMBL
  ENSSSCT00060101825.1 UniProtKB/TrEMBL
  ENSSSCT00065066974.1 UniProtKB/TrEMBL
  ENSSSCT00065066975.1 UniProtKB/TrEMBL
  ENSSSCT00065066981.1 UniProtKB/TrEMBL
InterPro Angiomotin UniProtKB/TrEMBL
  Angiomotin_C UniProtKB/TrEMBL
KEGG Report ssc:100513610 UniProtKB/TrEMBL
NCBI Gene AMOTL1 ENTREZGENE
PANTHER ANGIOMOTIN UniProtKB/TrEMBL
  ANGIOMOTIN-LIKE PROTEIN 1 UniProtKB/TrEMBL
Pfam Angiomotin_C UniProtKB/TrEMBL
PRINTS ANGIOMOTIN UniProtKB/TrEMBL
UniProt A0A286ZR74 ENTREZGENE, UniProtKB/TrEMBL
  A0A287B809 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0MRX9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0MSF2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0MSJ7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0Y3J6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0Y507 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0ZEM4_PIG UniProtKB/TrEMBL
  A0A8D0ZL27_PIG UniProtKB/TrEMBL
  A0A8D1CGU3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1CSA2_PIG UniProtKB/TrEMBL
  A0A8D1CSK2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1P5Q3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1PDD4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1TKM2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1WSQ3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1WTM8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1Z2P4_PIG UniProtKB/TrEMBL
  A0A8D1Z2R7_PIG UniProtKB/TrEMBL
  F1STJ4 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:85284 ENTREZGENE