C2CD3 (C2 domain containing 3 centriole elongation regulator) - Rat Genome Database

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Gene: C2CD3 (C2 domain containing 3 centriole elongation regulator) Sus scrofa
Analyze
Symbol: C2CD3
Name: C2 domain containing 3 centriole elongation regulator
RGD ID: 13876047
Description: INVOLVED IN brain development (ortholog); cilium assembly (ortholog); embryonic digit morphogenesis (ortholog); ASSOCIATED WITH 3-methylglutaconic aciduria type 7b (ortholog); Agenesis of Corpus Callosum (ortholog); asphyxiating thoracic dystrophy (ortholog); FOUND IN centriolar satellite (inferred); centriole (inferred); centrosome (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: C2 calcium dependent domain containing 3; C2 domain-containing protein 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl98,393,612 - 8,512,848 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.198,393,610 - 8,512,843 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.299,289,856 - 9,349,672 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:30032202  


Genomics

Comparative Map Data
C2CD3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl98,393,612 - 8,512,848 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.198,393,610 - 8,512,843 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.299,289,856 - 9,349,672 (-)NCBISscrofa10.2Sscrofa10.2susScr3
C2CD3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381174,012,718 - 74,171,002 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1174,012,718 - 74,171,210 (-)EnsemblGRCh38hg38GRCh38
GRCh371173,723,763 - 73,882,047 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361173,423,128 - 73,559,712 (-)NCBINCBI36Build 36hg18NCBI36
Celera1171,052,284 - 71,188,859 (-)NCBICelera
Cytogenetic Map11q13.4NCBI
HuRef1170,041,381 - 70,177,322 (-)NCBIHuRef
CHM1_11173,629,333 - 73,766,320 (-)NCBICHM1_1
T2T-CHM13v2.01173,942,048 - 74,100,346 (-)NCBIT2T-CHM13v2.0
C2cd3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397100,021,440 - 100,119,366 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7100,021,440 - 100,119,359 (+)EnsemblGRCm39 Ensembl
GRCm387100,372,229 - 100,470,159 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7100,372,233 - 100,470,152 (+)EnsemblGRCm38mm10GRCm38
MGSCv377107,520,743 - 107,618,668 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367100,248,501 - 100,344,232 (+)NCBIMGSCv36mm8
Celera7100,709,229 - 100,807,748 (+)NCBICelera
Cytogenetic Map7E2NCBI
cM Map754.35NCBI
C2cd3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81164,127,304 - 164,225,088 (+)NCBIGRCr8
mRatBN7.21154,715,151 - 154,812,955 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1154,715,310 - 154,812,520 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1162,709,885 - 162,807,531 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01169,889,987 - 169,987,632 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01162,763,942 - 162,861,529 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01165,382,279 - 165,480,088 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1165,382,690 - 165,479,655 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01171,583,008 - 171,680,742 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41157,774,397 - 157,892,744 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11157,853,000 - 157,955,514 (+)NCBI
Celera1152,799,056 - 152,895,063 (+)NCBICelera
Cytogenetic Map1q32NCBI
C2cd3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541417,444,515 - 17,558,245 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541417,444,299 - 17,557,912 (+)NCBIChiLan1.0ChiLan1.0
C2CD3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2974,954,310 - 75,113,879 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11175,998,226 - 76,157,932 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01169,085,434 - 69,244,791 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11172,392,606 - 72,551,620 (-)NCBIpanpan1.1PanPan1.1panPan2
UCP3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12124,272,522 - 24,290,304 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2124,277,896 - 24,288,639 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2124,049,763 - 24,055,700 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02124,484,075 - 24,496,484 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2124,484,070 - 24,496,484 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12124,284,466 - 24,290,404 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02124,484,328 - 24,490,265 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02124,399,875 - 24,405,814 (+)NCBIUU_Cfam_GSD_1.0
C2cd3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494761,499,810 - 61,642,747 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364983,099,396 - 3,242,335 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364983,099,419 - 3,242,334 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
C2CD3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1165,282,311 - 65,436,007 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl165,282,318 - 65,435,834 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604360,428,341 - 60,584,199 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
C2cd3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248172,880,976 - 3,042,004 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248172,880,775 - 3,060,399 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in C2CD3
5820 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 1 1 1
Low 9 4 3 4 2 23 2 2 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000016187   ⟹   ENSSSCP00000015754
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl98,393,612 - 8,512,848 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000084538   ⟹   ENSSSCP00000060245
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl98,406,653 - 8,512,708 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000098719   ⟹   ENSSSCP00000079126
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl98,393,612 - 8,512,848 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000105558   ⟹   ENSSSCP00000080382
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl98,414,211 - 8,512,848 (-)Ensembl
RefSeq Acc Id: XM_021062487   ⟹   XP_020918146
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.198,393,610 - 8,512,843 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020918146   ⟸   XM_021062487
- UniProtKB: A0A8D1ICR6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000015754   ⟸   ENSSSCT00000016187
RefSeq Acc Id: ENSSSCP00000060245   ⟸   ENSSSCT00000084538
RefSeq Acc Id: ENSSSCP00000079126   ⟸   ENSSSCT00000098719
RefSeq Acc Id: ENSSSCP00000080382   ⟸   ENSSSCT00000105558
Protein Domains
C2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000014835 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005005951 UniProtKB/TrEMBL
  ENSSSCG00045023251 UniProtKB/TrEMBL
  ENSSSCG00070018839 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000016187 ENTREZGENE
  ENSSSCT00000016187.5 UniProtKB/TrEMBL
  ENSSSCT00000084538.2 UniProtKB/TrEMBL
  ENSSSCT00000098719.1 UniProtKB/TrEMBL
  ENSSSCT00000105558.1 UniProtKB/TrEMBL
  ENSSSCT00005009259.1 UniProtKB/TrEMBL
  ENSSSCT00005009303.1 UniProtKB/TrEMBL
  ENSSSCT00045040282.1 UniProtKB/TrEMBL
  ENSSSCT00070037228.1 UniProtKB/TrEMBL
  ENSSSCT00070037250.1 UniProtKB/TrEMBL
  ENSSSCT00070037254.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.150 UniProtKB/TrEMBL
InterPro C2_C2CD3 UniProtKB/TrEMBL
  C2_dom UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
NCBI Gene C2CD3 ENTREZGENE
PANTHER C2 DOMAIN-CONTAINING PROTEIN 3 UniProtKB/TrEMBL
  UNCHARACTERIZED UniProtKB/TrEMBL
Pfam PF00168 UniProtKB/TrEMBL
PROSITE PS50004 UniProtKB/TrEMBL
SMART SM00239 UniProtKB/TrEMBL
Superfamily-SCOP SSF49562 UniProtKB/TrEMBL
UniProt A0A4X1UP74_PIG UniProtKB/TrEMBL
  A0A4X1UQU8_PIG UniProtKB/TrEMBL
  A0A4X1URG1_PIG UniProtKB/TrEMBL
  A0A5G2QDW0_PIG UniProtKB/TrEMBL
  A0A8D0LFU6_PIG UniProtKB/TrEMBL
  A0A8D1ICR6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8W4FI52_PIG UniProtKB/TrEMBL
  A0A8W4FMH1_PIG UniProtKB/TrEMBL
  F1SUR6_PIG UniProtKB/TrEMBL
VGNC ID VGNC:85992 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-06-18 C2CD3  C2 domain containing 3 centriole elongation regulator  C2CD3  C2 calcium dependent domain containing 3  Symbol and/or name change 5135510 APPROVED