SLC39A8 (solute carrier family 39 member 8) - Rat Genome Database

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Gene: SLC39A8 (solute carrier family 39 member 8) Sus scrofa
Analyze
Symbol: SLC39A8
Name: solute carrier family 39 member 8
RGD ID: 13873846
Description: ENCODES a protein that exhibits metal ion transmembrane transporter activity (inferred); monoatomic cation:bicarbonate symporter activity (inferred); zinc:bicarbonate symporter activity (inferred); INVOLVED IN arginine metabolic process (ortholog); cadmium ion transmembrane transport (ortholog); cartilage homeostasis (ortholog); PARTICIPATES IN iron uptake pathway; ASSOCIATED WITH beta-mannosidosis (ortholog); congenital disorder of glycosylation type IIn (ortholog); Crohn's disease (ortholog); FOUND IN apical plasma membrane (inferred); basolateral plasma membrane (inferred); lysosomal membrane (inferred); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: solute carrier family 39 (zinc transporter), member 8 tv2; zinc transporter ZIP8
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8118,605,402 - 118,678,107 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.18118,604,852 - 118,678,115 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28127,753,647 - 127,825,292 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SLC39A8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8118,605,402 - 118,678,107 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.18118,604,852 - 118,678,115 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28127,753,647 - 127,825,292 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SLC39A8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384102,251,041 - 102,345,482 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4102,251,080 - 102,431,258 (-)EnsemblGRCh38hg38GRCh38
GRCh374103,172,198 - 103,266,639 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 364103,401,844 - 103,485,371 (-)NCBINCBI36Build 36hg18NCBI36
Build 344103,539,998 - 103,623,526NCBI
Celera4100,470,678 - 100,565,146 (-)NCBICelera
Cytogenetic Map4q24NCBI
HuRef498,909,550 - 99,003,934 (-)NCBIHuRef
CHM1_14103,148,714 - 103,243,025 (-)NCBICHM1_1
T2T-CHM13v2.04105,565,252 - 105,659,701 (-)NCBIT2T-CHM13v2.0
Slc39a8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393135,522,644 - 135,594,333 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3135,531,040 - 135,594,333 (+)EnsemblGRCm39 Ensembl
GRCm383135,816,882 - 135,888,572 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3135,825,279 - 135,888,572 (+)EnsemblGRCm38mm10GRCm38
MGSCv373135,488,455 - 135,551,536 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363135,763,475 - 135,825,778 (+)NCBIMGSCv36mm8
Celera3142,245,991 - 142,312,950 (+)NCBICelera
Cytogenetic Map3G3NCBI
cM Map363.04NCBI
Slc39a8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82226,845,686 - 226,992,668 (+)NCBIGRCr8
mRatBN7.22224,171,787 - 224,319,326 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2224,256,654 - 224,319,129 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2231,982,580 - 232,044,754 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02229,882,319 - 229,944,486 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02224,746,913 - 224,809,087 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02241,028,851 - 241,092,584 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2241,029,693 - 241,092,582 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02259,584,747 - 259,648,098 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42233,340,397 - 233,403,461 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12233,327,136 - 233,390,197 (+)NCBI
Celera2216,458,405 - 216,522,357 (+)NCBICelera
Cytogenetic Map2q43NCBI
Slc39a8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554966,040,029 - 6,109,907 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554966,016,727 - 6,106,965 (+)NCBIChiLan1.0ChiLan1.0
SLC39A8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23100,339,570 - 100,430,481 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14100,626,388 - 100,716,146 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0494,675,458 - 94,770,380 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14105,339,488 - 105,433,813 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4105,339,488 - 105,433,568 (-)Ensemblpanpan1.1panPan2
SLC39A8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13223,727,920 - 23,801,459 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3223,729,476 - 23,800,941 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3218,223,143 - 18,296,028 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03223,949,019 - 24,021,586 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3223,949,029 - 24,022,702 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13223,928,002 - 24,000,562 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03223,708,061 - 23,781,012 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03216,083,043 - 16,156,566 (+)NCBIUU_Cfam_GSD_1.0
Slc39a8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530117,620,065 - 17,693,363 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936520962,756 - 1,037,274 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936520961,376 - 1,036,801 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC39A8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1750,355,756 - 50,451,253 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl750,367,436 - 50,451,510 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603728,867,139 - 28,956,324 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc39a8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248305,514,780 - 5,574,894 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248305,514,595 - 5,573,250 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SLC39A8
2978 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence


Ensembl Acc Id: ENSSSCT00000010041   ⟹   ENSSSCP00000009778
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl8118,605,293 - 118,684,039 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000040082   ⟹   ENSSSCP00000038853
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl8118,605,402 - 118,678,107 (+)Ensembl
RefSeq Acc Id: XM_013979001   ⟹   XP_013834455
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.18118,605,402 - 118,678,113 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021101717   ⟹   XP_020957376
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.18118,605,287 - 118,678,115 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021101718   ⟹   XP_020957377
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.18118,604,852 - 118,678,113 (+)NCBI
Sequence:
RefSeq Acc Id: XP_020957377   ⟸   XM_021101718
- UniProtKB: A0A480EKF5 (UniProtKB/TrEMBL),   A0A8D0YLS2 (UniProtKB/TrEMBL),   A0A8D0V689 (UniProtKB/TrEMBL),   M3TYX7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020957376   ⟸   XM_021101717
- UniProtKB: A0A480EKF5 (UniProtKB/TrEMBL),   A0A8D0YLS2 (UniProtKB/TrEMBL),   A0A8D0V689 (UniProtKB/TrEMBL),   M3TYX7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013834455   ⟸   XM_013979001
- UniProtKB: A0A480EKF5 (UniProtKB/TrEMBL),   A0A8D0YLS2 (UniProtKB/TrEMBL),   A0A8D0V689 (UniProtKB/TrEMBL),   M3TYX7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000038853   ⟸   ENSSSCT00000040082
Ensembl Acc Id: ENSSSCP00000009778   ⟸   ENSSSCT00000010041


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000009169 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00025036547 UniProtKB/TrEMBL
  ENSSSCG00030002292 UniProtKB/TrEMBL
  ENSSSCG00035004895 UniProtKB/TrEMBL
  ENSSSCG00055020455 UniProtKB/TrEMBL
  ENSSSCG00065024178 UniProtKB/TrEMBL
  ENSSSCG00070017522 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000040082 ENTREZGENE
  ENSSSCT00000040082.1 UniProtKB/TrEMBL
  ENSSSCT00025049826.1 UniProtKB/TrEMBL
  ENSSSCT00030002983.1 UniProtKB/TrEMBL
  ENSSSCT00035006164.1 UniProtKB/TrEMBL
  ENSSSCT00055040248.1 UniProtKB/TrEMBL
  ENSSSCT00065032222.1 UniProtKB/TrEMBL
  ENSSSCT00070034663.1 UniProtKB/TrEMBL
  ENSSSCT00070034681.1 UniProtKB/TrEMBL
  ENSSSCT00070034686.1 UniProtKB/TrEMBL
  ENSSSCT00070034694.1 UniProtKB/TrEMBL
InterPro ZIP UniProtKB/TrEMBL
  ZIP_Transporter UniProtKB/TrEMBL
KEGG Report ssc:100524695 UniProtKB/TrEMBL
NCBI Gene SLC39A8 ENTREZGENE
PANTHER METAL CATION SYMPORTER ZIP8 UniProtKB/TrEMBL
  SOLUTE CARRIER FAMILY 39 UniProtKB/TrEMBL
Pfam Zip UniProtKB/TrEMBL
UniProt A0A480EKF5 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1UG27_PIG UniProtKB/TrEMBL
  A0A8D0V689 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0YLS2 ENTREZGENE, UniProtKB/TrEMBL
  M3TYX7 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:93109 ENTREZGENE