ATP1B2 (ATPase Na+/K+ transporting subunit beta 2) - Rat Genome Database

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Gene: ATP1B2 (ATPase Na+/K+ transporting subunit beta 2) Sus scrofa
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Symbol: ATP1B2
Name: ATPase Na+/K+ transporting subunit beta 2
RGD ID: 13872770
Description: ENCODES a protein that exhibits P-type sodium:potassium-exchanging transporter activity (ortholog); protein heterodimerization activity (ortholog); INVOLVED IN lateral ventricle development (ortholog); motor behavior (ortholog); neuronal-glial interaction involved in hindbrain glial-mediated radial cell migration (ortholog); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; alfentanil pharmacodynamics pathway; ASSOCIATED WITH cerebellar ataxia (ortholog); common variable immunodeficiency (ortholog); dyskeratosis congenita (ortholog); FOUND IN apical plasma membrane (ortholog); astrocyte projection (ortholog); cell periphery (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOW QUALITY PROTEIN: sodium/potassium-transporting ATPase subunit beta-2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1252,925,693 - 52,932,637 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11252,925,697 - 52,932,638 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21255,241,662 - 55,248,610 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
acebutolol pharmacodynamics pathway  (ISO)
adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway  (ISO)
alfentanil pharmacodynamics pathway  (ISO)
amiloride pharmacodynamics pathway  (ISO)
amiodarone pharmacodynamics pathway  (ISO)
amlodipine pharmacodynamics pathway  (ISO)
atenolol pharmacodynamics pathway  (ISO)
bendroflumethiazide pharmacodynamics pathway  (ISO)
betaxolol pharmacodynamics pathway  (ISO)
bisoprolol pharmacodynamics pathway  (ISO)
bumetanide pharmacodynamics pathway  (ISO)
bupivacaine pharmacodynamics pathway  (ISO)
bupranolol drug pathway  (ISO)
bupranolol pharmacodynamics pathway  (ISO)
buprenorphine pharmacodynamics pathway  (ISO)
carvedilol pharmacodynamics pathway  (ISO)
chloroprocaine pharmacodynamics pathway  (ISO)
chlorothiazide pharmacodynamics pathway  (ISO)
chlorthalidone pharmacodynamics pathway  (ISO)
citalopram pharmacodynamics pathway  (ISO)
cocaine pharmacodynamics pathway  (ISO)
codeine and morphine pharmacodynamics pathway  (ISO)
cystinuria pathway  (ISO)
desipramine pharmacodynamics pathway  (ISO)
diltiazem pharmacodynamics pathway  (ISO)
diphenoxylate pharmacodynamics pathway  (ISO)
disopyramide pharmacodynamics pathway  (ISO)
dobutamine pharmacodynamics pathway  (ISO)
eplerenone pharmacodynamics pathway  (ISO)
escitalopram pharmacodynamics pathway  (ISO)
esmolol pharmacodynamics pathway  (ISO)
etacrynic acid pharmacodynamics pathway  (ISO)
ethylmorphine pharmacodynamics pathway  (ISO)
fentanyl pharmacodynamics pathway  (ISO)
flecainde pharmacodynamics pathway  (ISO)
fluoxetine pharmacodynamics pathway  (ISO)
fosphenytoin pharmacodynamics pathway  (ISO)
furosemide pharmacodynamics pathway  (ISO)
Hartnup disease pathway  (ISO)
heroin pharmacodynamics pathway  (ISO)
hydrochlorothiazide pharmacodynamics pathway  (ISO)
hydrocodone pharmacodynamics pathway  (ISO)
hydroflumethiazide pharmacodynamics pathway  (ISO)
hydromorphone pharmacodynamics pathway  (ISO)
ibutilide pharmacodynamics pathway  (ISO)
iminoglycinuria pathway  (ISO)
imipramine pharmacodynamics pathway  (ISO)
isoprenaline pharmacodynamics pathway  (ISO)
isradipine pharmacodynamics pathway  (ISO)
lactose degradation pathway  (ISO)
levacetylmethadol pharmacodynamics pathway  (ISO)
levobunolol pharmacodynamics pathway  (ISO)
levobupivacaine phgarmacodynamics pathway  (ISO)
levorphanol pharmacodynamics pathway  (ISO)
lidocaine pharmacodynamics pathway  (ISO)
lysinuric protein intolerance pathway  (ISO)
mepivacaine pharmacodynamics pathway  (ISO)
methadone pharmacodynamics pathway  (ISO)
metolazone pharmacodynamics pathway  (ISO)
metoprolol pharmacodynamics pathway  (ISO)
mexiletine pharmacodynamics pathway  (ISO)
nadolol pharmacodynamics pathway  (ISO)
nalbuphine pharmacodynamics pathway  (ISO)
naloxone pharmacodynamics pathway  (ISO)
naltrexone pharmacodynamics pathway  (ISO)
nebivolol pharmacodynamics pathway  (ISO)
nicotine pharmacodynamics pathway  (ISO)
nifedipine pharmacodynamics pathway  (ISO)
nimodipine pharmacodynamics pathway  (ISO)
nisoldipine pharmacodynamics pathway  (ISO)
nitrendipine pharmacodynamics pathway  (ISO)
oxybuprocaine pharmacodynamics pathway  (ISO)
oxycodone pharmacodynamics pathway  (ISO)
oxymorphone pharmacodynamics pathway  (ISO)
penbutolol pharmacodynamics pathway  (ISO)
pentazocine pharmacodynamics pathway  (ISO)
phenytoin pharmacodynamics pathway  (ISO)
pindolol pharmacodynamics pathway  (ISO)
prilocaine pharmacodynamics pathway  (ISO)
procainamide pharmacodynamics pathway  (ISO)
procaine pharmacodynamics pathway  (ISO)
propranolol pharmacodynamics pathway  (ISO)
quinidine pharmacodynamics pathway  (ISO)
remifentanil pharmacodynamics pathway  (ISO)
ropivacaine pharmacodynamics pathway  (ISO)
sotalol pharmacodynamics pathway  (ISO)
spironolactone pharmacodynamics pathway  (ISO)
timolol pharmacodynamics pathway  (ISO)
torasemide pharmacodynamics pathway  (ISO)
tramadol pharmacodynamics pathway  (ISO)
trehalose degradation pathway  (ISO)
triamterene pharmacodynamics pathway  (ISO)
trichlormethiazide pharmacodynamics pathway  (ISO)
verapamil pharmacodynamics pathway  (ISO)

References

Genomics

Comparative Map Data
ATP1B2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1252,925,693 - 52,932,637 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11252,925,697 - 52,932,638 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21255,241,662 - 55,248,610 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ATP1B2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl177,646,627 - 7,657,770 (+)EnsemblGRCh38hg38GRCh38
GRCh38177,646,627 - 7,657,770 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37177,549,945 - 7,561,088 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36177,494,979 - 7,501,814 (+)NCBINCBI36hg18NCBI36
Build 34177,494,978 - 7,501,814NCBI
Celera177,580,634 - 7,587,472 (+)NCBI
Cytogenetic Map17p13.1NCBI
HuRef177,448,147 - 7,454,987 (+)NCBIHuRef
CHM1_1177,563,405 - 7,570,244 (+)NCBICHM1_1
Atp1b2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391169,490,554 - 69,496,786 (-)NCBIGRCm39mm39
GRCm39 Ensembl1169,490,562 - 69,496,768 (-)Ensembl
GRCm381169,599,728 - 69,605,978 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1169,599,736 - 69,605,942 (-)EnsemblGRCm38mm10GRCm38
MGSCv371169,413,252 - 69,419,462 (-)NCBIGRCm37mm9NCBIm37
MGSCv361169,415,948 - 69,422,024 (-)NCBImm8
Celera1176,563,216 - 76,569,425 (-)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1142.86NCBI
Atp1b2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21054,318,698 - 54,324,933 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1054,318,701 - 54,324,933 (-)Ensembl
Rnor_6.01056,205,622 - 56,211,879 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1056,205,625 - 56,211,891 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01055,951,260 - 55,957,510 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41056,418,323 - 56,424,465 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11056,431,946 - 56,438,088 (-)NCBI
Celera1053,472,960 - 53,479,196 (-)NCBICelera
Cytogenetic Map10q24NCBI
Atp1b2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554679,261,775 - 9,268,743 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554679,261,775 - 9,268,743 (-)NCBIChiLan1.0ChiLan1.0
ATP1B2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1177,669,997 - 7,675,730 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl177,669,626 - 7,673,834 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0177,681,831 - 7,688,710 (+)NCBIMhudiblu_PPA_v0panPan3
ATP1B2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1532,548,591 - 32,553,911 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl532,549,167 - 32,553,504 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha532,687,510 - 32,694,048 (+)NCBI
ROS_Cfam_1.0532,653,348 - 32,659,884 (+)NCBI
UMICH_Zoey_3.1532,621,044 - 32,627,582 (+)NCBI
UNSW_CanFamBas_1.0532,577,297 - 32,583,829 (+)NCBI
UU_Cfam_GSD_1.0532,756,419 - 32,762,956 (+)NCBI
Atp1b2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560247,433,820 - 47,440,238 (+)NCBI
SpeTri2.0NW_004936595908,019 - 914,426 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ATP1B2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1167,030,016 - 7,035,620 (+)NCBI
ChlSab1.1 Ensembl167,030,055 - 7,037,754 (+)Ensembl
Vero_WHO_p1.0NW_02366605914,373,302 - 14,379,044 (-)NCBI
Atp1b2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462478610,254,979 - 10,261,508 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 1 21
Low 7 3 2 3 2 2
Below cutoff 3 1 2 1 1 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000019535   ⟹   ENSSSCP00000019017
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1252,925,693 - 52,932,637 (+)Ensembl
RefSeq Acc Id: XM_003131945   ⟹   XP_003131993
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11252,925,697 - 52,932,638 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003131993 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_003131993   ⟸   XM_003131945
- Sequence:
RefSeq Acc Id: ENSSSCP00000019017   ⟸   ENSSSCT00000019535


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000017951 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000019017 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000019535 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.1660 UniProtKB/TrEMBL
InterPro Na/K_ATPase_sub_beta UniProtKB/TrEMBL
  Na/K_ATPase_sub_beta_sf UniProtKB/TrEMBL
NCBI Gene ATP1B2 ENTREZGENE
PANTHER PTHR11523 UniProtKB/TrEMBL
Pfam Na_K-ATPase UniProtKB/TrEMBL
PROSITE ATPASE_NA_K_BETA_1 UniProtKB/TrEMBL
  ATPASE_NA_K_BETA_2 UniProtKB/TrEMBL
TIGRFAMs Na_K_ATPase_bet UniProtKB/TrEMBL
UniProt F1ST41_PIG UniProtKB/TrEMBL
VGNC ID VGNC:85643 ENTREZGENE