ARFGEF2 (ADP ribosylation factor guanine nucleotide exchange factor 2) - Rat Genome Database

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Gene: ARFGEF2 (ADP ribosylation factor guanine nucleotide exchange factor 2) Sus scrofa
Analyze
Symbol: ARFGEF2
Name: ADP ribosylation factor guanine nucleotide exchange factor 2
RGD ID: 13872471
Description: ENCODES a protein that exhibits GABA receptor binding (ortholog); myosin binding (ortholog); INVOLVED IN endomembrane system organization (ortholog); exocytosis (ortholog); ASSOCIATED WITH developmental and epileptic encephalopathy 26 (ortholog); Developmental Disabilities (ortholog); genetic disease (ortholog); FOUND IN asymmetric synapse (ortholog); axonemal microtubule (ortholog); cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: brefeldin A-inhibited guanine nucleotide-exchange protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1750,631,092 - 50,732,243 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11750,631,844 - 50,732,253 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21756,982,797 - 57,082,784 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:14681463   PMID:17145712  


Genomics

Comparative Map Data
ARFGEF2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1750,631,092 - 50,732,243 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11750,631,844 - 50,732,253 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21756,982,797 - 57,082,784 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ARFGEF2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2048,921,711 - 49,036,693 (+)EnsemblGRCh38hg38GRCh38
GRCh382048,921,711 - 49,036,693 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372047,538,248 - 47,653,230 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362046,971,682 - 47,086,637 (+)NCBINCBI36hg18NCBI36
Build 342046,971,833 - 47,083,645NCBI
Celera2044,242,891 - 44,357,843 (+)NCBI
Cytogenetic Map20q13.13NCBI
HuRef2044,289,793 - 44,403,088 (+)NCBIHuRef
CHM1_12047,442,300 - 47,557,463 (+)NCBICHM1_1
Arfgef2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392166,647,371 - 166,739,972 (+)NCBIGRCm39mm39
GRCm39 Ensembl2166,647,508 - 166,739,972 (+)Ensembl
GRCm382166,805,451 - 166,898,052 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2166,805,588 - 166,898,052 (+)EnsemblGRCm38mm10GRCm38
MGSCv372166,631,081 - 166,723,552 (+)NCBIGRCm37mm9NCBIm37
MGSCv362166,496,769 - 166,589,258 (+)NCBImm8
Celera2172,745,033 - 172,837,457 (+)NCBICelera
Cytogenetic Map2H3NCBI
Arfgef2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.23155,547,504 - 155,633,652 (+)NCBI
Rnor_6.0 Ensembl3163,570,532 - 163,656,626 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.03163,570,435 - 163,656,612 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03169,732,829 - 169,817,296 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43157,967,942 - 158,051,359 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13157,873,977 - 157,957,394 (+)NCBI
Celera3154,129,988 - 154,212,427 (+)NCBICelera
Cytogenetic Map3q42NCBI
Arfgef2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554459,070,234 - 9,153,213 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554459,069,803 - 9,153,746 (-)NCBIChiLan1.0ChiLan1.0
ARFGEF2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12046,330,174 - 46,442,518 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2046,327,753 - 46,442,518 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02045,262,330 - 45,376,237 (+)NCBIMhudiblu_PPA_v0panPan3
ARFGEF2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12435,648,650 - 35,744,815 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2435,648,431 - 35,744,584 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2434,891,532 - 34,987,633 (+)NCBI
ROS_Cfam_1.02436,353,676 - 36,449,469 (+)NCBI
UMICH_Zoey_3.12435,595,002 - 35,690,750 (+)NCBI
UNSW_CanFamBas_1.02435,728,513 - 35,824,458 (+)NCBI
UU_Cfam_GSD_1.02436,269,736 - 36,365,697 (+)NCBI
Arfgef2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640189,719,109 - 189,809,174 (-)NCBI
SpeTri2.0NW_0049365145,172,752 - 5,262,823 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARFGEF2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1214,947,347 - 15,058,217 (-)NCBI
ChlSab1.1 Ensembl214,947,351 - 15,030,772 (-)Ensembl
Arfgef2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247906,290,021 - 6,381,492 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 4 2 3 5 15 2 2 3
Low 6 2 2 8 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000008164   ⟹   ENSSSCP00000007948
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1750,631,921 - 50,732,243 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000066737   ⟹   ENSSSCP00000063042
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1750,631,924 - 50,731,561 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000067659   ⟹   ENSSSCP00000071114
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1750,631,092 - 50,729,530 (+)Ensembl
RefSeq Acc Id: XM_003483981   ⟹   XP_003484029
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11750,631,844 - 50,732,253 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005654245   ⟹   XP_005654302
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11750,631,854 - 50,732,253 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003484029 (Get FASTA)   NCBI Sequence Viewer  
  XP_005654302 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein JAG69719 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_003484029   ⟸   XM_003483981
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_005654302   ⟸   XM_005654245
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSSSCP00000063042   ⟸   ENSSSCT00000066737
RefSeq Acc Id: ENSSSCP00000071114   ⟸   ENSSSCT00000067659
RefSeq Acc Id: ENSSSCP00000007948   ⟸   ENSSSCT00000008164
Protein Domains
SEC7


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000007460 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000007948 UniProtKB/TrEMBL
  ENSSSCP00000063042 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000071114 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000008164 UniProtKB/TrEMBL
  ENSSSCT00000066737 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000067659 UniProtKB/TrEMBL
Gene3D-CATH 1.10.1000.11 UniProtKB/TrEMBL
InterPro ARM-type_fold UniProtKB/TrEMBL
  DCB_dom UniProtKB/TrEMBL
  Sec7_C UniProtKB/TrEMBL
  Sec7_C_sf UniProtKB/TrEMBL
  Sec7_dom UniProtKB/TrEMBL
  Sec7_dom_sf UniProtKB/TrEMBL
  Sec7_N UniProtKB/TrEMBL
KEGG Report ssc:100523757 UniProtKB/TrEMBL
NCBI Gene ARFGEF2 ENTREZGENE
Pfam DCB UniProtKB/TrEMBL
  DUF1981 UniProtKB/TrEMBL
  Sec7 UniProtKB/TrEMBL
  Sec7_N UniProtKB/TrEMBL
PROSITE SEC7 UniProtKB/TrEMBL
SMART Sec7 UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/TrEMBL
  SSF48425 UniProtKB/TrEMBL
UniProt A0A5G2QXW0_PIG UniProtKB/TrEMBL
  A0A5G2R1X7_PIG UniProtKB/TrEMBL
  F1SBE8_PIG UniProtKB/TrEMBL
VGNC ID VGNC:95672 ENTREZGENE