MTF1 (metal regulatory transcription factor 1) - Rat Genome Database

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Gene: MTF1 (metal regulatory transcription factor 1) Sus scrofa
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Symbol: MTF1
Name: metal regulatory transcription factor 1
RGD ID: 13870293
Description: ENCODES a protein that exhibits cis-regulatory region sequence-specific DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); DNA-binding transcription factor activity (inferred); INVOLVED IN cartilage homeostasis (ortholog); positive regulation of DNA-templated transcription (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); autistic disorder (ortholog); Charcot-Marie-Tooth disease dominant intermediate C (ortholog); FOUND IN cytoplasm (inferred); nucleoplasm (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: PROVISIONAL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl693,839,205 - 93,884,409 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1693,837,195 - 93,884,427 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2686,652,512 - 86,655,135 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:30032202  


Genomics

Comparative Map Data
MTF1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl693,839,205 - 93,884,409 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1693,837,195 - 93,884,427 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2686,652,512 - 86,655,135 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MTF1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38137,809,574 - 37,859,592 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl137,809,574 - 37,859,592 (-)EnsemblGRCh38hg38GRCh38
GRCh37138,275,246 - 38,325,264 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36138,047,826 - 38,097,879 (-)NCBINCBI36Build 36hg18NCBI36
Build 34137,948,943 - 37,994,324NCBI
Celera136,553,063 - 36,603,115 (-)NCBICelera
Cytogenetic Map1p34.3NCBI
HuRef136,393,522 - 36,443,287 (-)NCBIHuRef
CHM1_1138,391,063 - 38,441,086 (-)NCBICHM1_1
T2T-CHM13v2.0137,676,462 - 37,726,477 (-)NCBIT2T-CHM13v2.0
Mtf1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Build 34136,271,267 - 36,284,160NCBI
GRCm394124,696,342 - 124,743,593 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4124,695,897 - 124,743,593 (+)EnsemblGRCm39 Ensembl
GRCm384124,802,549 - 124,849,800 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4124,802,104 - 124,849,800 (+)EnsemblGRCm38mm10GRCm38
MGSCv374124,479,793 - 124,527,044 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364124,304,876 - 124,349,954 (+)NCBIMGSCv36mm8
Celera4123,124,096 - 123,171,046 (+)NCBICelera
Cytogenetic Map4D2.2NCBI
cM Map457.91NCBI
Mtf1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85142,347,024 - 142,391,810 (+)NCBIGRCr8
mRatBN7.25137,062,319 - 137,107,136 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5137,062,376 - 137,107,136 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5139,767,233 - 139,812,075 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05141,537,246 - 141,582,093 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05141,544,424 - 141,589,269 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05142,797,340 - 142,843,896 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5142,797,366 - 142,842,122 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl5142,332,607 - 142,376,370 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05146,567,984 - 146,614,540 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45144,135,674 - 144,180,430 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15144,145,451 - 144,187,287 (+)NCBI
Celera5135,585,105 - 135,629,881 (+)NCBICelera
Cytogenetic Map5q36NCBI
Mtf1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545215,580,460 - 15,627,844 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545215,580,460 - 15,627,844 (-)NCBIChiLan1.0ChiLan1.0
MTF1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21188,977,327 - 189,027,954 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11188,106,469 - 188,152,667 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0137,088,744 - 37,134,318 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1138,432,716 - 38,482,142 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl138,438,294 - 38,482,142 (-)Ensemblpanpan1.1panPan2
MTF1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1154,679,945 - 4,723,111 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl154,680,372 - 4,717,561 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha154,921,849 - 4,965,016 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0154,808,453 - 4,851,650 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl154,808,870 - 4,846,324 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1154,668,306 - 4,711,440 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0154,734,863 - 4,777,974 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0154,751,184 - 4,794,296 (+)NCBIUU_Cfam_GSD_1.0
Mtf1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505854,160,425 - 54,202,806 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647419,981,466 - 20,027,536 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647419,981,483 - 20,027,541 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MTF1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12095,002,623 - 95,052,366 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2095,003,504 - 95,046,718 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603321,758,719 - 21,810,019 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mtf1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476420,515,307 - 20,557,105 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476420,510,925 - 20,557,134 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in MTF1
594 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence


Ensembl Acc Id: ENSSSCT00000055389   ⟹   ENSSSCP00000032204
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl693,839,205 - 93,884,399 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000071853   ⟹   ENSSSCP00000060666
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl693,839,205 - 93,884,409 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000085846   ⟹   ENSSSCP00000067376
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl693,839,205 - 93,884,405 (-)Ensembl
RefSeq Acc Id: NM_001243544   ⟹   NP_001230473
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1693,839,174 - 93,884,404 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021093300   ⟹   XP_020948959
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1693,840,097 - 93,882,254 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021093301   ⟹   XP_020948960
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1693,837,195 - 93,884,427 (-)NCBI
Sequence:
RefSeq Acc Id: XP_020948960   ⟸   XM_021093301
- Peptide Label: isoform X2
- UniProtKB: A0A8D1X5Q1 (UniProtKB/TrEMBL),   A0A8D0LNL4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001230473   ⟸   NM_001243544
- UniProtKB: A0A8D0PA72 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020948959   ⟸   XM_021093300
- Peptide Label: isoform X1
- UniProtKB: A0A4X1VQZ5 (UniProtKB/TrEMBL),   A0A5G2Q8U0 (UniProtKB/TrEMBL),   A0A8D0PA72 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000032204   ⟸   ENSSSCT00000055389
Ensembl Acc Id: ENSSSCP00000067376   ⟸   ENSSSCT00000085846
Ensembl Acc Id: ENSSSCP00000060666   ⟸   ENSSSCT00000071853
Protein Domains
C2H2-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000037516 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015057677 UniProtKB/TrEMBL
  ENSSSCG00025029314 UniProtKB/TrEMBL
  ENSSSCG00030039960 UniProtKB/TrEMBL
  ENSSSCG00035022495 UniProtKB/TrEMBL
  ENSSSCG00040012714 UniProtKB/TrEMBL
  ENSSSCG00045003908 UniProtKB/TrEMBL
  ENSSSCG00050058563 UniProtKB/TrEMBL
  ENSSSCG00055002547 UniProtKB/TrEMBL
  ENSSSCG00060074524 UniProtKB/TrEMBL
  ENSSSCG00065002016 UniProtKB/TrEMBL
  ENSSSCG00070027051 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000055389.3 UniProtKB/TrEMBL
  ENSSSCT00000071853 ENTREZGENE
  ENSSSCT00000071853.2 UniProtKB/TrEMBL
  ENSSSCT00015076909.1 UniProtKB/TrEMBL
  ENSSSCT00025040018.1 UniProtKB/TrEMBL
  ENSSSCT00030055661.1 UniProtKB/TrEMBL
  ENSSSCT00035029375.1 UniProtKB/TrEMBL
  ENSSSCT00040016825.1 UniProtKB/TrEMBL
  ENSSSCT00045006476.1 UniProtKB/TrEMBL
  ENSSSCT00050079828.1 UniProtKB/TrEMBL
  ENSSSCT00055004878.1 UniProtKB/TrEMBL
  ENSSSCT00060101909.1 UniProtKB/TrEMBL
  ENSSSCT00065002525.1 UniProtKB/TrEMBL
  ENSSSCT00065002532.1 UniProtKB/TrEMBL
  ENSSSCT00070054247.1 UniProtKB/TrEMBL
Gene3D-CATH Classic Zinc Finger UniProtKB/TrEMBL
InterPro GLI_C2H2-zinc-finger UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/TrEMBL
NCBI Gene MTF1 ENTREZGENE
PANTHER PTHR19818:SF131 UniProtKB/TrEMBL
  ZINC FINGER PROTEIN ZIC AND GLI UniProtKB/TrEMBL
Pfam zf-C2H2 UniProtKB/TrEMBL
PROSITE ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
SMART ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP SSF57667 UniProtKB/TrEMBL
UniProt A0A286ZKW4_PIG UniProtKB/TrEMBL
  A0A4X1VQZ5 ENTREZGENE, UniProtKB/TrEMBL
  A0A5G2Q8U0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0LNL4 ENTREZGENE
  A0A8D0PA72 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1X5Q1 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:90443 ENTREZGENE