ASAH2 (N-acylsphingosine amidohydrolase 2) - Rat Genome Database

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Gene: ASAH2 (N-acylsphingosine amidohydrolase 2) Sus scrofa
Analyze
Symbol: ASAH2
Name: N-acylsphingosine amidohydrolase 2
RGD ID: 13869453
Description: ENCODES a protein that exhibits calcium ion binding (ortholog); dihydroceramidase activity (ortholog); phytoceramidase activity (ortholog); INVOLVED IN cellular response to cytokine stimulus (ortholog); ceramide metabolic process (ortholog); negative regulation of apoptotic signaling pathway (ortholog); ASSOCIATED WITH celiac disease (ortholog); Hirschsprung's disease (ortholog); liver disease (ortholog); FOUND IN extracellular exosome (ortholog); Golgi apparatus (ortholog); membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: ASAH2B; N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2B; neutral ceramidase
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1499,025,005 - 99,129,100 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11499,018,111 - 99,141,374 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214107,865,243 - 107,969,067 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

Genomics

Comparative Map Data
ASAH2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1499,025,005 - 99,129,100 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11499,018,111 - 99,141,374 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214107,865,243 - 107,969,067 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ASAH2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1050,182,778 - 50,279,720 (-)EnsemblGRCh38hg38GRCh38
GRCh381050,184,861 - 50,251,564 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371051,944,621 - 52,011,276 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361051,617,078 - 51,678,319 (-)NCBINCBI36hg18NCBI36
Celera1075,112,386 - 75,164,225 (-)NCBI
Cytogenetic Map10q11.23NCBI
HuRef1045,946,293 - 46,007,775 (-)NCBIHuRef
CHM1_11052,228,873 - 52,290,233 (-)NCBICHM1_1
Asah2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391931,962,046 - 32,080,540 (-)NCBIGRCm39mm39
GRCm39 Ensembl1931,959,997 - 32,085,611 (-)Ensembl
GRCm381931,984,646 - 32,103,140 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1931,982,597 - 32,108,211 (-)EnsemblGRCm38mm10GRCm38
MGSCv371932,059,136 - 32,177,630 (-)NCBIGRCm37mm9NCBIm37
MGSCv361932,050,643 - 32,169,137 (-)NCBImm8
Celera1932,772,701 - 32,889,548 (-)NCBICelera
Cytogenetic Map19C1NCBI
Asah2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21229,865,662 - 229,973,253 (-)NCBI
Rnor_6.0 Ensembl1250,557,044 - 250,630,677 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01250,557,042 - 250,665,083 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01257,790,747 - 257,898,648 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41236,000,768 - 236,072,477 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11236,164,792 - 236,236,500 (-)NCBI
Celera1226,986,485 - 227,059,852 (-)NCBICelera
Cytogenetic Map1q52NCBI
Asah2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554255,840,355 - 5,931,891 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554255,840,355 - 5,931,891 (+)NCBIChiLan1.0ChiLan1.0
LOC100985247
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11048,970,524 - 49,025,245 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1048,969,434 - 49,025,336 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01046,842,830 - 46,908,811 (-)NCBIMhudiblu_PPA_v0panPan3
ASAH2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12637,136,601 - 37,228,215 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2637,136,897 - 37,218,783 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2637,022,117 - 37,103,999 (-)NCBI
ROS_Cfam_1.02638,669,614 - 38,751,828 (-)NCBI
UMICH_Zoey_3.12636,577,467 - 36,659,447 (-)NCBI
UNSW_CanFamBas_1.02636,157,741 - 36,239,965 (-)NCBI
UU_Cfam_GSD_1.02637,398,030 - 37,480,024 (-)NCBI
Asah2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721376,700,488 - 76,788,640 (-)NCBI
SpeTri2.0NW_0049367352,004,373 - 2,092,501 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ASAH2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1980,409,649 - 80,501,527 (-)NCBI
ChlSab1.1 Ensembl980,409,478 - 80,476,731 (-)Ensembl
Vero_WHO_p1.0NW_02366604841,060,629 - 41,133,632 (-)NCBI
Asah2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462479112,906,908 - 13,059,033 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 11
Low 2 1 1 10 1
Below cutoff 5 4 2 4 1 2 2 1 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000011417   ⟹   ENSSSCP00000011121
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1499,025,005 - 99,129,100 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000069496   ⟹   ENSSSCP00000068780
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1499,025,005 - 99,129,100 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000074825   ⟹   ENSSSCP00000069712
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1499,025,005 - 99,129,100 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000079643   ⟹   ENSSSCP00000063013
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1499,025,005 - 99,129,100 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000086528   ⟹   ENSSSCP00000060774
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1499,025,304 - 99,100,640 (-)Ensembl
RefSeq Acc Id: XM_005671250   ⟹   XP_005671307
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11499,018,111 - 99,130,995 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021072693   ⟹   XP_020928352
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11499,018,111 - 99,141,374 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021072694   ⟹   XP_020928353
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11499,018,111 - 99,130,995 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005671307 (Get FASTA)   NCBI Sequence Viewer  
  XP_020928352 (Get FASTA)   NCBI Sequence Viewer  
  XP_020928353 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_020928352   ⟸   XM_021072693
- Sequence:
RefSeq Acc Id: XP_020928353   ⟸   XM_021072694
- Sequence:
RefSeq Acc Id: XP_005671307   ⟸   XM_005671250
- UniProtKB: F1SCZ9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000063013   ⟸   ENSSSCT00000079643
RefSeq Acc Id: ENSSSCP00000069712   ⟸   ENSSSCT00000074825
RefSeq Acc Id: ENSSSCP00000011121   ⟸   ENSSSCT00000011417
RefSeq Acc Id: ENSSSCP00000068780   ⟸   ENSSSCT00000069496
RefSeq Acc Id: ENSSSCP00000060774   ⟸   ENSSSCT00000086528
Protein Domains
Ceramidase_alk   Ceramidse_alk_C


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000010432 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000011121 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000060774 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000063013 UniProtKB/TrEMBL
  ENSSSCP00000068780 UniProtKB/TrEMBL
  ENSSSCP00000069712 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000011417 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000069496 UniProtKB/TrEMBL
  ENSSSCT00000074825 UniProtKB/TrEMBL
  ENSSSCT00000079643 UniProtKB/TrEMBL
  ENSSSCT00000086528 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.2300 UniProtKB/TrEMBL
InterPro Ceramidase_alk UniProtKB/TrEMBL
  NCDase_C_sf UniProtKB/TrEMBL
  NEUT/ALK_ceramidase_C UniProtKB/TrEMBL
  NEUT/ALK_ceramidase_N UniProtKB/TrEMBL
KEGG Report ssc:100157065 UniProtKB/TrEMBL
NCBI Gene ASAH2 ENTREZGENE
PANTHER PTHR12670 UniProtKB/TrEMBL
Pfam Ceramidase_alk UniProtKB/TrEMBL
  Ceramidse_alk_C UniProtKB/TrEMBL
UniProt A0A5G2Q9X4_PIG UniProtKB/TrEMBL
  A0A5G2QGS8_PIG UniProtKB/TrEMBL
  A0A5G2QXA5_PIG UniProtKB/TrEMBL
  A0A5G2QXV9_PIG UniProtKB/TrEMBL
  F1SCZ9 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:97888 ENTREZGENE