CETN2 (centrin 2) - Rat Genome Database

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Pathways
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Gene: CETN2 (centrin 2) Sus scrofa
Analyze
Symbol: CETN2
Name: centrin 2
RGD ID: 13866895
Description: ENCODES a protein that exhibits calcium ion binding (inferred); G-protein beta/gamma-subunit complex binding (inferred); heterotrimeric G-protein binding (inferred); INVOLVED IN centriole replication (inferred); mitotic cell cycle (inferred); nucleotide-excision repair (inferred); PARTICIPATES IN nucleotide excision repair pathway; ASSOCIATED WITH autistic disorder (ortholog); genetic disease (ortholog); syndromic X-linked intellectual disability Lubs type (ortholog); FOUND IN centrosome (ortholog); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: centrin-2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX123,902,241 - 123,906,230 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X123,902,240 - 123,906,046 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X141,372,858 - 141,376,715 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:14681463   PMID:15679890   PMID:16940283   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CETN2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX123,902,241 - 123,906,230 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X123,902,240 - 123,906,046 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X141,372,858 - 141,376,715 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CETN2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X152,826,994 - 152,830,757 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX152,826,994 - 152,830,757 (-)EnsemblGRCh38hg38GRCh38
GRCh37X151,995,538 - 151,999,301 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X151,746,527 - 151,749,957 (-)NCBINCBI36Build 36hg18NCBI36
Build 34X151,666,440 - 151,669,869NCBI
CeleraX152,330,255 - 152,333,685 (-)NCBICelera
Cytogenetic MapXq28NCBI
CHM1_1X151,870,461 - 151,873,892 (-)NCBICHM1_1
T2T-CHM13v2.0X151,093,478 - 151,097,241 (-)NCBIT2T-CHM13v2.0
Cetn2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X71,957,137 - 71,961,967 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX71,957,138 - 71,962,017 (-)EnsemblGRCm39 Ensembl
GRCm38X72,913,565 - 72,918,344 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX72,913,532 - 72,918,411 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X70,158,904 - 70,163,683 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X69,166,285 - 69,171,064 (-)NCBIMGSCv36mm8
CeleraX63,848,732 - 63,853,510 (-)NCBICelera
Cytogenetic MapXA7.3NCBI
cM MapX37.29NCBI
Cetn2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X155,812,212 - 155,817,186 (-)NCBIGRCr8
mRatBN7.2X150,769,944 - 150,774,833 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX150,769,953 - 150,774,919 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX152,961,970 - 152,966,859 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X156,494,314 - 156,499,203 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X154,037,424 - 154,042,313 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X152,927,852 - 152,933,095 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX152,927,718 - 152,932,953 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01148,656,625 - 148,661,864 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X158,917,650 - 158,923,210 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X158,991,770 - 158,994,109 (-)NCBI
Celera1131,733,984 - 131,739,094 (-)NCBICelera
Cytogenetic MapXq37NCBI
Cetn2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554988,131,295 - 8,135,751 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554988,131,356 - 8,135,751 (-)NCBIChiLan1.0ChiLan1.0
CETN2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X152,891,513 - 152,895,020 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X152,895,116 - 152,898,630 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X142,401,679 - 142,405,206 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X152,320,893 - 152,324,362 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX152,320,893 - 152,324,362 (-)Ensemblpanpan1.1panPan2
CETN2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X120,714,676 - 120,720,012 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX106,083,242 - 106,088,561 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X122,939,332 - 122,944,667 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX122,939,337 - 122,944,584 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X119,655,565 - 119,660,884 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X122,146,252 - 122,151,579 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X122,021,281 - 122,026,614 (-)NCBIUU_Cfam_GSD_1.0
Cetn2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X117,977,261 - 117,982,406 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936714274,036 - 279,381 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936714274,098 - 279,177 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CETN2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X127,339,163 - 127,342,626 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX127,338,862 - 127,341,575 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606565,172,423 - 65,175,920 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cetn2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248834,035,647 - 4,039,732 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248834,035,647 - 4,039,758 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CETN2
33 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 7 2 3 5 23 2 3 3
Low 3 2 2
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000013947   ⟹   ENSSSCP00000013564
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 EnsemblX123,902,241 - 123,906,230 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000037330   ⟹   ENSSSCP00000040579
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 EnsemblX123,903,049 - 123,906,230 (-)Ensembl
RefSeq Acc Id: XM_005673970   ⟹   XP_005674027
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1X123,902,240 - 123,906,046 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_005674027   ⟸   XM_005673970
- UniProtKB: A0A4X1TCT6 (UniProtKB/TrEMBL),   F2Z563 (UniProtKB/TrEMBL),   A0A8D1YFS9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000013564   ⟸   ENSSSCT00000013947
RefSeq Acc Id: ENSSSCP00000040579   ⟸   ENSSSCT00000037330
Protein Domains
EF-hand


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000012757 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005019438 UniProtKB/TrEMBL
  ENSSSCG00015060632 UniProtKB/TrEMBL
  ENSSSCG00025000011 UniProtKB/TrEMBL
  ENSSSCG00030053289 UniProtKB/TrEMBL
  ENSSSCG00035059843 UniProtKB/TrEMBL
  ENSSSCG00040048264 UniProtKB/TrEMBL
  ENSSSCG00045015277 UniProtKB/TrEMBL
  ENSSSCG00050028178 UniProtKB/TrEMBL
  ENSSSCG00055003877 UniProtKB/TrEMBL
  ENSSSCG00060013839 UniProtKB/TrEMBL
  ENSSSCG00065030369 UniProtKB/TrEMBL
  ENSSSCG00070008795 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000013947 ENTREZGENE
  ENSSSCT00000013947.6 UniProtKB/TrEMBL
  ENSSSCT00000037330.3 UniProtKB/TrEMBL
  ENSSSCT00005030966.1 UniProtKB/TrEMBL
  ENSSSCT00015081370.1 UniProtKB/TrEMBL
  ENSSSCT00015081510.1 UniProtKB/TrEMBL
  ENSSSCT00025000024.1 UniProtKB/TrEMBL
  ENSSSCT00030074388.1 UniProtKB/TrEMBL
  ENSSSCT00030074412.1 UniProtKB/TrEMBL
  ENSSSCT00035080227.1 UniProtKB/TrEMBL
  ENSSSCT00035080233.1 UniProtKB/TrEMBL
  ENSSSCT00040065087.1 UniProtKB/TrEMBL
  ENSSSCT00040065177.1 UniProtKB/TrEMBL
  ENSSSCT00045025922.1 UniProtKB/TrEMBL
  ENSSSCT00045025973.1 UniProtKB/TrEMBL
  ENSSSCT00050037893.1 UniProtKB/TrEMBL
  ENSSSCT00050037902.1 UniProtKB/TrEMBL
  ENSSSCT00055007610.1 UniProtKB/TrEMBL
  ENSSSCT00055007618.1 UniProtKB/TrEMBL
  ENSSSCT00060018257.1 UniProtKB/TrEMBL
  ENSSSCT00060018260.1 UniProtKB/TrEMBL
  ENSSSCT00065041049.1 UniProtKB/TrEMBL
  ENSSSCT00065041060.1 UniProtKB/TrEMBL
  ENSSSCT00070017050.1 UniProtKB/TrEMBL
  ENSSSCT00070017055.1 UniProtKB/TrEMBL
Gene3D-CATH EF-hand UniProtKB/TrEMBL
InterPro EF-hand-dom_pair UniProtKB/TrEMBL
  EF_Hand_1_Ca_BS UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/TrEMBL
  RNA-helicase_DEAD-box_CS UniProtKB/TrEMBL
KEGG Report ssc:606742 UniProtKB/TrEMBL
NCBI Gene CETN2 ENTREZGENE
PANTHER CALCIUM BINDING PROTEIN UniProtKB/TrEMBL
  PTHR23050:SF305 UniProtKB/TrEMBL
Pfam EF-hand_6 UniProtKB/TrEMBL
  EF-hand_7 UniProtKB/TrEMBL
PROSITE DEAD_ATP_HELICASE UniProtKB/TrEMBL
  EF_HAND_1 UniProtKB/TrEMBL
  EF_HAND_2 UniProtKB/TrEMBL
SMART EFh UniProtKB/TrEMBL
Superfamily-SCOP SSF47473 UniProtKB/TrEMBL
UniProt A0A287A9T8_PIG UniProtKB/TrEMBL
  A0A4X1TCT6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1PH95_PIG UniProtKB/TrEMBL
  A0A8D1YFS9 ENTREZGENE, UniProtKB/TrEMBL
  F2Z563 ENTREZGENE
UniProt Secondary F2Z563 UniProtKB/TrEMBL