LRRC30 (leucine rich repeat containing 30)

Gene: LRRC30 (leucine rich repeat containing 30) Sus scrofa

Analyze

Symbol:

LRRC30

Name:

leucine rich repeat containing 30

RGD ID:

13865847

Description:

ASSOCIATED WITH chromosome 18p deletion syndrome (ortholog); genetic disease (ortholog); intellectual disability (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

leucine-rich repeat-containing protein 30

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	6	100,290,257 - 100,292,242 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

chromosome 18p deletion syndrome (ISO)

genetic disease (ISO)

intellectual disability (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

signal transduction (IBA)

References

Additional References at PubMed

PMID:22301074

Genomics

Comparative Map Data

LRRC30
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	6	100,290,257 - 100,292,242 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

LRRC30
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	18	7,231,089 - 7,232,044 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	18	7,231,089 - 7,232,044 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	18	7,231,087 - 7,232,042 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	18	7,221,137 - 7,222,042 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	18	7,116,420 - 7,117,325 (+)	NCBI		Celera
Cytogenetic Map	18	p11.23	NCBI
HuRef	18	7,194,738 - 7,195,643 (+)	NCBI		HuRef
CHM1_1	18	7,231,124 - 7,232,029 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	18	7,394,203 - 7,395,158 (+)	NCBI		T2T-CHM13v2.0

Lrrc30
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	67,937,960 - 67,939,718 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	67,937,959 - 67,939,718 (-)	Ensembl		GRCm39 Ensembl
GRCm38	17	67,630,965 - 67,632,723 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	67,630,964 - 67,632,723 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	17	67,980,305 - 67,982,063 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	17	67,535,910 - 67,537,668 (-)	NCBI		MGSCv36	mm8
Celera	17	71,927,267 - 71,929,025 (-)	NCBI		Celera
Cytogenetic Map	17	E1.1	NCBI
cM Map	17	38.8	NCBI

Lrrc30
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	115,071,263 - 115,072,931 (-)	NCBI		GRCr8
mRatBN7.2	9	107,624,479 - 107,626,147 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	107,625,182 - 107,626,084 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	116,016,400 - 116,018,068 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	121,138,622 - 121,140,290 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	119,482,288 - 119,483,956 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	115,849,029 - 115,854,043 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	115,849,732 - 115,850,634 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	115,339,600 - 115,342,049 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	106,782,842 - 106,783,744 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	9	104,784,465 - 104,789,479 (-)	NCBI		Celera
Cytogenetic Map	9	q38	NCBI

Lrrc30
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955402	4,175,557 - 4,176,462 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955402	4,174,990 - 4,178,170 (-)	NCBI	ChiLan1.0	ChiLan1.0

LRRC30
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	17	31,209,601 - 31,210,556 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	18	16,902,194 - 16,903,149 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	18	7,042,813 - 7,043,785 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	18	9,367,109 - 9,368,081 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	18	9,367,147 - 9,368,052 (-)	Ensembl	panpan1.1		panPan2

LRRC30
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	7	73,554,459 - 73,556,247 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	7	73,554,654 - 73,555,559 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	7	72,948,600 - 72,951,861 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	7	73,606,542 - 73,609,803 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	7	73,606,695 - 73,607,600 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	7	73,310,212 - 73,313,473 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	7	73,339,808 - 73,343,069 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	7	73,634,085 - 73,637,346 (+)	NCBI		UU_Cfam_GSD_1.0

Lrrc30
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404944	70,074,393 - 70,076,449 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936670	590,579 - 591,481 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936670	590,401 - 592,138 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LRRC30
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	18	66,258,023 - 66,261,327 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	18	66,259,044 - 66,259,946 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666050	41,175,983 - 41,177,898 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Lrrc30
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624770	16,571,982 - 16,572,887 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624770	16,571,858 - 16,573,510 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in LRRC30
41 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	musculoskeletal system
High
Medium
Low	2
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_021096068	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000045	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

XM_021096068 ⟹ XP_020951727

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	6	100,290,257 - 100,292,242 (-)	NCBI

Sequence:

show sequence

AGATGGAGAGAGAGAGAGGTGTGTACCCAGGCAGGTCTCTTCAGACTACTTTCCAGGACCAGGG
ACACTGTGCTCACCTTCCAAGCCAGCCACTCCAGTGCTGTCCAAACATTTAAAGAGCACCCAGC
TAAAGCAGGCACTCTCTATAAAGCAGATGGCCCCAGAGCTTCTCTGCAAGAAAATGCAGGTGGG
GTCCAAACCCCTTCACCCTCTACTCGAGGAATCATCTCTGACCAGCACCATCTAAAACCCTGGC
CTGGAGGATTCCTGAAGTCCAGGCTCTGTCTCTTCTGCATGATTCACCGCATTTGGAATTGCTG
TGTGCATTACGGTCAGCCGATTCTTAGCTTTAGGGACATAGCTGTAAGAGCATTGAGCCCAGCT
CAGCTCCGGGGTCCGGATGAGTCTGAGACCTGCACACAGCCTGGCTTTAATTTTCCCCTTGGCT
TCTTTTCAGAGATGAGCTTGTGAATCACCCTGCTCAGCTGTGACACCCCAGAGGAGCAGAGAGG
GAAAGTCAGACACCGCCTCCCTGTGACCTGTTTGCACTCCCCAGGCCAGTGAAGTGCGGCCAGA
ATGACAGTGACAGCTGCCCCGTGGTGTTCAGAGGGACCTGAGCCGTTCAGTTCTGCAGCTTCGG
GGACAAGTGTATCATTACAGCCCGGCTGCTCCGAGAGAGGCCACTTCAACCCAGCCCCGGGAAC
ACGCGCAGCGCCGCGGCCAGGCATCTGGCCCCTGAGTCCTGCTCCACCTGCGGCAGCCCCTGCC
CGTGGCTCCCACCGCCTGATCGGCTTCAGCAGCGGGGCCAGACCCCGTCCCCACACGCGGGCAC
AGAGGAGAGGAGGACGGCAGGTAAATGGGGGCCAGGCAGTCTGGTGCCTGCTGCAAGGACAAGG
GCCTCCCGGGGCCGGGGCCCCTGCGGGGGAGGCAGAAGTTCTCCCCGTGGGACGAGGCCCTGCT
CCCGGGGAGGGACCCGCGGTGCCTGCTGAAGCGGGGCCTGCGGCATGTCAGCTTCAGCCTGGTC
ACCACGGGCATGACCGACGCGCCCGACTTCCTGTGGGGCCTGTCGGAGGTGCAGAAGCTCAATC
TGTCCCACAACCAGCTCCGGGCCCTCCCGCCCGACGTGGGGAGGCTGACACGGCTGGTCGTCCT
CAACTTGTGCGGCAACCGCCTGAAGAGCCTGCCCCGGGAGCTCAGCCTCCTCCGCAGCCTCAAG
GTCCTGTTCCTGCACATGAACTGCCTGACGGAGCTGCCAGCCGAGCTGAGCGCCTGCCAGAGCC
TGGAGGTTCTGGGCCTGTCGCACAACTGCTTGTCCCAGCTCCCCGCCAGCTTCGCTGATCTCGC
CCGGCTGCGCAAGCTCAACCTCAGCCACAACCGCTTTGCCCACATCCCCGTCTGCGTGTTCGCG
CTCAAGGAGCTGGACTTCCTGCACGTGGGCTCCAACCGCCTGGAGAACATTGCCGAGAGCATCC
AGTGCCTGGCCAGCCTGCAGATCTTCATTGCCGAGAGCAACAACATCCACGCCTTCCCGCGCGC
CCTCTGTCTGCTCACCAGCCTGGAGCTGCTCAACTTGAACAACAACAACATCCAGACCCTCCCA
GAGGAGCTCTACCTGCTGTGTAGACTGGCGAGGATCGCTTGGAACCCCATGGACAAAGGGCTCC
ATATCTCCCGCAACCCTTTATCCAAACCCCTGCCGGAGCTGCTGGAGGGGGGTCTGGAGATGCT
TTTCGGTTACCTGAAGGACAAAAAACACACTTGATGGGGGCACTGGAGGCTCGGACAGACAGCC
GGTACATCCCTTGTCTACACCTCCTCCTCTTCCTGTTCCTGTGGGTCAACCCTGTGTTGCTATT
TGCTAAATTGCACTGAGCACCCATGCTAGGGGGTGTTTGCTTTTGGCTCTGTAGGTTCCTTATA
ACCCGCCTTTATTGTTCATCTCATTCTAAACATAAATGGAAAGAAGGCTTGGGTTTTCTCCAAA
AA

hide sequence

Protein Sequences


Protein RefSeqs	XP_020951727	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000023303
	ENSSSCP00000023303.2
	ENSSSCP00005005351.1
	ENSSSCP00015018208.1
	ENSSSCP00025010855.1
	ENSSSCP00025040982.1
	ENSSSCP00035037081.1
	ENSSSCP00040000532.1
	ENSSSCP00045039296.1
	ENSSSCP00055025152.1
	ENSSSCP00060004609.1
	ENSSSCP00065035762.1
	ENSSSCP00070044471.1

RefSeq Acc Id:

XP_020951727 ⟸ XM_021096068

- UniProtKB:

A0A4X1VLS2 (UniProtKB/TrEMBL), I3LGV9 (UniProtKB/TrEMBL), A0A8D1SR55 (UniProtKB/TrEMBL), A0A8D1ZHN2 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MGARQSGACCKDKGLPGPGPLRGRQKFSPWDEALLPGRDPRCLLKRGLRHVSFSLVTTGMTDAP
DFLWGLSEVQKLNLSHNQLRALPPDVGRLTRLVVLNLCGNRLKSLPRELSLLRSLKVLFLHMNC
LTELPAELSACQSLEVLGLSHNCLSQLPASFADLARLRKLNLSHNRFAHIPVCVFALKELDFLH
VGSNRLENIAESIQCLASLQIFIAESNNIHAFPRALCLLTSLELLNLNNNNIQTLPEELYLLCR
LARIAWNPMDKGLHISRNPLSKPLPELLEGGLEMLFGYLKDKKHT

hide sequence

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000023672	ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCG00005005963	UniProtKB/TrEMBL
	ENSSSCG00015034660	UniProtKB/TrEMBL
	ENSSSCG00025018946	UniProtKB/TrEMBL
	ENSSSCG00025068048	UniProtKB/TrEMBL
	ENSSSCG00035065873	UniProtKB/TrEMBL
	ENSSSCG00040001685	UniProtKB/TrEMBL
	ENSSSCG00045032991	UniProtKB/TrEMBL
	ENSSSCG00055016043	UniProtKB/TrEMBL
	ENSSSCG00060009494	UniProtKB/TrEMBL
	ENSSSCG00065059984	UniProtKB/TrEMBL
	ENSSSCG00070026224	UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000022830	ENTREZGENE
	ENSSSCT00000022830.3	UniProtKB/TrEMBL
	ENSSSCT00005009042.1	UniProtKB/TrEMBL
	ENSSSCT00015045966.1	UniProtKB/TrEMBL
	ENSSSCT00025025683.1	UniProtKB/TrEMBL
	ENSSSCT00025093410.1	UniProtKB/TrEMBL
	ENSSSCT00035088730.1	UniProtKB/TrEMBL
	ENSSSCT00040001985.1	UniProtKB/TrEMBL
	ENSSSCT00045056326.1	UniProtKB/TrEMBL
	ENSSSCT00055031603.1	UniProtKB/TrEMBL
	ENSSSCT00060012253.1	UniProtKB/TrEMBL
	ENSSSCT00065082136.1	UniProtKB/TrEMBL
	ENSSSCT00070052531.1	UniProtKB/TrEMBL
Gene3D-CATH	3.80.10.10	UniProtKB/TrEMBL
InterPro	Leu-rich_rpt	UniProtKB/TrEMBL
	Leu-rich_rpt_typical-subtyp	UniProtKB/TrEMBL
	LRR_dom_sf	UniProtKB/TrEMBL
NCBI Gene	LRRC30	ENTREZGENE
PANTHER	LEUCINE-RICH REPEAT AND DEATH DOMAIN-CONTAINING PROTEIN 1	UniProtKB/TrEMBL
	PTHR48051	UniProtKB/TrEMBL
Pfam	LRR_1	UniProtKB/TrEMBL
	LRR_8	UniProtKB/TrEMBL
PROSITE	LRR	UniProtKB/TrEMBL
SMART	LRR_TYP	UniProtKB/TrEMBL
Superfamily-SCOP	L domain-like	UniProtKB/TrEMBL
UniProt	A0A4X1VLS2	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D1SR55	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D1ZHN2	ENTREZGENE, UniProtKB/TrEMBL
	I3LGV9	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:98494	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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