BTBD16 (BTB domain containing 16)

Gene: BTBD16 (BTB domain containing 16) Sus scrofa

Analyze

Symbol:

BTBD16

Name:

BTB domain containing 16

RGD ID:

13864033

Description:

ASSOCIATED WITH craniosynostosis (ortholog); genetic disease (ortholog); prostate cancer (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

BTB/POZ domain-containing protein 16

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	BTBD16 (BTB domain containing 16)	HGNC	Ensembl, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):	Btbd16 (BTB domain containing 16)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Btbd16 (BTB domain containing 16)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Btbd16 (BTB domain containing 16)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	BTBD16 (BTB domain containing 16)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	BTBD16 (BTB domain containing 16)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Btbd16 (BTB domain containing 16)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	BTBD16 (BTB domain containing 16)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Btbd16 (BTB domain containing 16)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	131,861,480 - 131,920,479 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	131,864,394 - 131,920,317 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	143,155,452 - 143,200,677 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

craniosynostosis (ISO)

genetic disease (ISO)

prostate cancer (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Molecular Function

protein binding (ISO)

References

Genomics

Comparative Map Data

BTBD16
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	131,861,480 - 131,920,479 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	131,864,394 - 131,920,317 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	143,155,452 - 143,200,677 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

BTBD16
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	10	122,271,296 - 122,338,159 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	10	122,271,296 - 122,338,159 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	10	124,030,811 - 124,097,674 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	10	124,020,811 - 124,087,666 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	10	124,020,810 - 124,087,666	NCBI
Celera	10	117,763,200 - 117,830,044 (+)	NCBI		Celera
Cytogenetic Map	10	q26.13	NCBI
HuRef	10	117,661,660 - 117,728,511 (+)	NCBI		HuRef
CHM1_1	10	124,315,437 - 124,382,305 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	10	123,167,581 - 123,234,437 (+)	NCBI		T2T-CHM13v2.0

Btbd16
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	130,375,799 - 130,427,631 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	130,375,799 - 130,427,629 (+)	Ensembl		GRCm39 Ensembl
GRCm38	7	130,774,069 - 130,825,901 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	130,774,069 - 130,825,899 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	137,917,583 - 137,969,413 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	130,565,217 - 130,617,045 (+)	NCBI		MGSCv36	mm8
Celera	7	130,589,531 - 130,640,147 (+)	NCBI		Celera
Cytogenetic Map	7	F3	NCBI
cM Map	7	73.19	NCBI

Btbd16
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	194,765,241 - 194,819,786 (+)	NCBI		GRCr8
mRatBN7.2	1	185,334,971 - 185,389,518 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	185,335,725 - 185,389,517 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	193,685,969 - 193,739,755 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	200,864,631 - 200,918,077 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	193,536,398 - 193,589,846 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	201,337,370 - 201,391,246 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	201,337,416 - 201,391,252 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	208,368,838 - 208,423,139 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	190,093,640 - 190,148,677 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	190,243,516 - 190,298,557 (+)	NCBI
Celera	1	182,950,183 - 183,002,291 (+)	NCBI		Celera
Cytogenetic Map	1	q37-q41	NCBI

Btbd16
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955477	559,685 - 627,305 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955477	560,095 - 627,017 (+)	NCBI	ChiLan1.0	ChiLan1.0

BTBD16
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	8	134,128,543 - 134,193,828 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	10	134,133,895 - 134,199,180 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	10	118,842,396 - 118,907,233 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	10	122,254,206 - 122,318,497 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	10	122,259,648 - 122,318,423 (+)	Ensembl	panpan1.1		panPan2

BTBD16
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	28	31,951,511 - 32,004,923 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	28	31,952,226 - 31,994,675 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	28	32,026,951 - 32,081,683 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	28	32,487,552 - 32,542,292 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	28	32,483,366 - 32,530,509 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	28	32,020,051 - 32,063,014 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	28	32,040,946 - 32,095,991 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	28	32,245,742 - 32,300,641 (+)	NCBI		UU_Cfam_GSD_1.0

Btbd16
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	14,405,643 - 14,452,881 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936486	11,110,228 - 11,155,580 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936486	11,112,148 - 11,155,652 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

BTBD16
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	9	115,005,070 - 115,073,976 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	9	115,010,795 - 115,073,899 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666048	76,290,056 - 76,371,993 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Btbd16
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624737	24,397,066 - 24,455,699 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624737	24,392,987 - 24,464,472 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in BTBD16
3160 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	nervous system	reproductive system
High
Medium
Low	1		1
Below cutoff	1	1

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_021073716	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000096	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CU582863	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSSCT00000030603 ⟹ ENSSSCP00000024204

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	14	131,861,480 - 131,920,479 (+)	Ensembl

RefSeq Acc Id:

ENSSSCT00000071051 ⟹ ENSSSCP00000072866

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	14	131,861,786 - 131,919,554 (+)	Ensembl

RefSeq Acc Id:

XM_021073716 ⟹ XP_020929375

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	14	131,864,394 - 131,920,317 (+)	NCBI

Sequence:

show sequence

ATGGATAAAAGGCACAAACCTCGGCTGGAACGCCAGATTGTTGGCTCAACCAACCGGTGGCGTT
TCCCCCAAGAGCCTTTCTCGGGGGACTTGCTGGCACGTTCCCAGATGTGCAAGGCTGTCAACAC
AGACTTTGATGAAGTTCTGAAGCACCCAGACAGGTTATGCATTTCACAATTTCAGAAAAATTTC
CCAAAGAATTTGAAGAGTGAAACCATCCAAAGTGGGGAGGCAGATGTGATTCTCGAGTGCCTTG
GCTTCAAATGGGAACTCCATCAGCCCCAGCTTTTTCAGTCTGAGACCTTGACCAAACTTTACCT
GATGGCCCTGGCCCGGGGTAACCTCGACCCCGAGCAGGAGCTGAAGAGGCTTCTGCAAGCTCAA
CTGCGTGGGAAGGTCAAAGAACAACACCCCGTGAAGAAGATAAGCATTTCCTTGAAGATCTATG
ACGCTCTGGTCACCAAAGCTGCCTTCGCCACCGCCCTGAAGAACCTCTACATCCCCGAGGTGAA
GATCAGCATGGAGGAGGTCCTGGGCGTGCTGGCTGCCGCCCACATTCTCCAGTTCCGCAGCCTG
TTTCAAAGGTGTGTGGCCATGATGACGAGTGAGCTCACTCCAGGCACCATCAAGAACTTCTACC
TGGCCGGCTGCAGGTACAAGGAAGAGCGGCTCACCACCGGCTGCGAGAAGTGGATGGAGATGAA
CTTGGTCCCTTTGATGGGGACACAGATCCACCTCCGGAAAGTCCCACAGGAGCTGCTCCACAAA
GTGCTGAGGTCCCCCAGGTTGTTTACTTTTAGTGAGTTTCACCTTCTGAAAACACTACTTTTGT
GGGTCTACTTGCAAATGAACAACAAAACACAGACCATTCCGGCGTATGAAACCATGGTGGCATT
TTTTAGCAGCTTCCCCAAGACGTGCTCCTTTCTGGAACAGGACGTAGGACAGACCTTGACGCCG
CTCTTCCTTTGCCTGCGTCTGCACGGCATCATCAAAGGCAAGCATCTGGAGGAGCTAAGGCACA
TTAACTTCTTCCCTGAATCCTGGCTGGTCCGGGTTACAGCCAGCCATTACCACGCACTGGAGAG
TGGGGGCGACATGGCCCACGTGAGAGATTTTACCACCCAGGCGGTGAGGTTCGGGCTGCTCTTT
AACCAGGAGTATACAACACACTCAAAGACGATTGCCATATATGGATTCTTCTTTGAGATAAAGG
GAATCAAACACGATACGACCTCGTATAGTTTCCACATGCAGAGAATAAGGCACACCGACCTGGA
ATTCCCCGCCTCGGTCTGTGAGCACAGCCCCATCAGCCTGAGGGCAGAGCGCTTGGTGACGTAC
GAGATCAGAGCCCAGACCCTGGTGGACAGCAAGTGGCAGGAGTTCAGGACGAACCAGATCACAC
AAAAATTTGGGTTGGCCAAGCCATCCTGCAAAAGCCATGCCTTGAAAATCCAAACTGTGGGCAT
CCCCATCTATGCAAGTTTTACATTCGTCTTCTCATTAGCTTAACTGTTTTCAGAGGCATCTATG
GGATTTTCTTTCTTCAACTGGTTCACATAAAAGGAAATAAAATGACCTTAAAGGGACCGCTCAA
GTATTCAGCTCTGAGTTCGTGGTGATGTCGTTGGAACGTCTGCCCACTGTCGCAGCCTGTGTCG
GATGCTCTAACAAAACACCACAGGCCGGGGGGCTTCTATGTAGAGAAGAAATTTATTTCAGTTC
TGGGGGCTGGAAGTCCCAGCTCAGGATTCTGTGGTGTCTGGTGAGAGCCTGCTTTCCAGTTCAC
GGACAGCCGTCTTCTCCCTGTGTCCTCAGAAGGTGGAAGAGGCCAGGAAGCTTTCTGGAGCTTG
TTTTCGTAAGAGCACTAATCCCATTTGTGAGTGCCCTGCTCTTGTGACCGAATCGCCCCCAAAG
CCTCCACTTCCTGGTGATGGTACCTTTGGGGGTTAGGATTCAGCATGTGAATTCTGCAGAGACA
CATTCAGAGCGTAACATTCACATTTGAATCATGTGAGGGTGGAAGGTGTCAGAGTCAATTTGCC
ATTGTTGACCCCCAAGCACCCTGAGTCCAGCCCTTACTTATTGCACTCTCGGGAGCACCCCAGG
GGACCACCAGCAGTTAACACCAAACTCCAGCTGAGAGCAGCGAGGCTCCCCTTTTCTGCCTCCT
GCACTGAACAGCACACCTGGCCGTGGTCCCTGGTAGTTTTGGCTGAGCGAGAACAAGAGGTAGG
AAGGGAAGCAAAGCAATTATAAACCAAACTGTGAAGGGGACTTCTCTTATTTACTGCCCCACCT
TTCTGTTTTTTATTATTTTGTTTTGTTTTATTTATTTATTTTTTTGTCTT

hide sequence

Protein Sequences


Protein RefSeqs	XP_020929375	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000024204
	ENSSSCP00000024204.3
	ENSSSCP00015004126.1
	ENSSSCP00055003828.1

RefSeq Acc Id:

XP_020929375 ⟸ XM_021073716

- UniProtKB:

A0A8D1TU41 (UniProtKB/TrEMBL), I3LJE4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MDKRHKPRLERQIVGSTNRWRFPQEPFSGDLLARSQMCKAVNTDFDEVLKHPDRLCISQFQKNF
PKNLKSETIQSGEADVILECLGFKWELHQPQLFQSETLTKLYLMALARGNLDPEQELKRLLQAQ
LRGKVKEQHPVKKISISLKIYDALVTKAAFATALKNLYIPEVKISMEEVLGVLAAAHILQFRSL
FQRCVAMMTSELTPGTIKNFYLAGCRYKEERLTTGCEKWMEMNLVPLMGTQIHLRKVPQELLHK
VLRSPRLFTFSEFHLLKTLLLWVYLQMNNKTQTIPAYETMVAFFSSFPKTCSFLEQDVGQTLTP
LFLCLRLHGIIKGKHLEELRHINFFPESWLVRVTASHYHALESGGDMAHVRDFTTQAVRFGLLF
NQEYTTHSKTIAIYGFFFEIKGIKHDTTSYSFHMQRIRHTDLEFPASVCEHSPISLRAERLVTY
EIRAQTLVDSKWQEFRTNQITQKFGLAKPSCKSHALKIQTVGIPIYASFTFVFSLA

hide sequence

RefSeq Acc Id:

ENSSSCP00000024204 ⟸ ENSSSCT00000030603

RefSeq Acc Id:

ENSSSCP00000072866 ⟸ ENSSSCT00000071051

Protein Domains

BTB/POZ

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000010701	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCG00015007851	UniProtKB/TrEMBL
	ENSSSCG00055002530	UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000030603	ENTREZGENE
	ENSSSCT00000030603.4	UniProtKB/TrEMBL
	ENSSSCT00015010435.1	UniProtKB/TrEMBL
	ENSSSCT00055004967.1	UniProtKB/TrEMBL
InterPro	BTBD16	UniProtKB/TrEMBL
	BTBD16_C	UniProtKB/TrEMBL
	SKP1/BTB/POZ_sf	UniProtKB/TrEMBL
NCBI Gene	BTBD16	ENTREZGENE
PANTHER	BTB/POZ DOMAIN-CONTAINING PROTEIN 16	UniProtKB/TrEMBL
	PTHR46843	UniProtKB/TrEMBL
Pfam	BTBD16_C	UniProtKB/TrEMBL
Superfamily-SCOP	SSF54695	UniProtKB/TrEMBL
UniProt	A0A8D1TU41	ENTREZGENE, UniProtKB/TrEMBL
	I3LJE4	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:85902	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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