CA8 (carbonic anhydrase 8) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: CA8 (carbonic anhydrase 8) Sus scrofa
Analyze
Symbol: CA8
Name: carbonic anhydrase 8
RGD ID: 13860810
Description: ENCODES a protein that exhibits carbonate dehydratase activity (inferred); zinc ion binding (inferred); INVOLVED IN phosphatidylinositol-mediated signaling (ortholog); ASSOCIATED WITH Cerebellar Ataxia, Mental Retardation, and Dysequilibrium Syndrome 3 (ortholog); intellectual disability (ortholog); FOUND IN cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Also known as: carbonic anhydrase-related protein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl473,047,847 - 73,141,991 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1473,047,867 - 73,172,215 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2479,510,120 - 79,573,391 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)

Molecular Function

References

Genomics

Comparative Map Data
CA8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl473,047,847 - 73,141,991 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1473,047,867 - 73,172,215 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2479,510,120 - 79,573,391 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CA8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl860,185,412 - 60,281,400 (-)EnsemblGRCh38hg38GRCh38
GRCh38860,185,412 - 60,281,400 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37861,097,971 - 61,193,959 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36861,263,977 - 61,356,508 (-)NCBINCBI36hg18NCBI36
Build 34861,263,976 - 61,356,508NCBI
Celera857,092,480 - 57,182,989 (-)NCBI
Cytogenetic Map8q12.1NCBI
HuRef856,589,359 - 56,681,767 (-)NCBIHuRef
CHM1_1861,150,010 - 61,246,037 (-)NCBICHM1_1
Car8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3948,141,493 - 8,239,226 (-)NCBIGRCm39mm39
GRCm39 Ensembl48,143,362 - 8,239,041 (-)Ensembl
GRCm3848,141,493 - 8,239,041 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl48,143,362 - 8,239,041 (-)EnsemblGRCm38mm10GRCm38
MGSCv3748,068,640 - 8,166,188 (-)NCBIGRCm37mm9NCBIm37
MGSCv3647,613,848 - 7,709,581 (-)NCBImm8
MGSCv3648,068,640 - 8,166,188 (-)NCBImm8
Celera48,024,484 - 8,115,866 (-)NCBICelera
Cytogenetic Map4A1NCBI
cM Map43.53NCBI
Ca8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2521,302,940 - 21,402,395 (-)NCBI
Rnor_6.0 Ensembl521,249,020 - 21,345,810 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0521,249,018 - 21,345,810 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0526,010,374 - 26,106,856 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4521,951,255 - 22,049,427 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1521,951,256 - 22,049,427 (-)NCBI
Celera520,578,323 - 20,675,389 (-)NCBICelera
Cytogenetic Map5q13NCBI
Ca8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544418,413,958 - 18,512,213 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544418,414,006 - 18,510,800 (+)NCBIChiLan1.0ChiLan1.0
CA8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1858,273,696 - 58,367,615 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl858,273,696 - 58,367,615 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0856,606,454 - 56,702,357 (-)NCBIMhudiblu_PPA_v0panPan3
CA8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12910,678,122 - 10,763,361 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2910,679,038 - 10,764,193 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2910,989,287 - 11,075,445 (-)NCBI
ROS_Cfam_1.02910,763,585 - 10,849,785 (-)NCBI
UMICH_Zoey_3.12910,765,703 - 10,851,540 (-)NCBI
UNSW_CanFamBas_1.02910,899,217 - 10,985,514 (-)NCBI
UU_Cfam_GSD_1.02911,167,585 - 11,253,944 (-)NCBI
Ca8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530361,800,602 - 61,889,623 (-)NCBI
SpeTri2.0NW_00493649612,895,858 - 12,984,303 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CA8
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1856,111,149 - 56,203,797 (-)NCBI
ChlSab1.1 Ensembl856,131,599 - 56,203,336 (-)Ensembl
Ca8
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474431,659,318 - 31,777,409 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system nervous system renal system reproductive system respiratory system
High
Medium 4 2 1
Low 6 2 1 5 19 1 2
Below cutoff 2 2 2 2 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000006830   ⟹   ENSSSCP00000006645
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl473,047,873 - 73,140,620 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000038512   ⟹   ENSSSCP00000055042
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl473,047,847 - 73,141,991 (+)Ensembl
RefSeq Acc Id: XM_021089339   ⟹   XP_020944998
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1473,047,868 - 73,140,610 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021089340   ⟹   XP_020944999
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1473,047,867 - 73,172,215 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021089341   ⟹   XP_020945000
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1473,047,873 - 73,140,610 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_020944998 (Get FASTA)   NCBI Sequence Viewer  
  XP_020944999 (Get FASTA)   NCBI Sequence Viewer  
  XP_020945000 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_020944999   ⟸   XM_021089340
- Sequence:
RefSeq Acc Id: XP_020944998   ⟸   XM_021089339
- Sequence:
RefSeq Acc Id: XP_020945000   ⟸   XM_021089341
- Sequence:
RefSeq Acc Id: ENSSSCP00000006645   ⟸   ENSSSCT00000006830
RefSeq Acc Id: ENSSSCP00000055042   ⟸   ENSSSCT00000038512
Protein Domains
Alpha-carbonic anhydrase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000006233 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00070001823 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000006645 UniProtKB/TrEMBL
  ENSSSCP00000055042 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00070002858 UniProtKB/TrEMBL
  ENSSSCP00070002866 UniProtKB/TrEMBL
  ENSSSCP00070002870 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000006830 UniProtKB/TrEMBL
  ENSSSCT00000038512 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00070003453 UniProtKB/TrEMBL
  ENSSSCT00070003464 UniProtKB/TrEMBL
  ENSSSCT00070003469 UniProtKB/TrEMBL
Gene3D-CATH 3.10.200.10 UniProtKB/TrEMBL
InterPro CA_dom UniProtKB/TrEMBL
  CA_dom_sf UniProtKB/TrEMBL
  Carbonic_anhydrase_a-class UniProtKB/TrEMBL
  Carbonic_anhydrase_a-class_CS UniProtKB/TrEMBL
  CARP_VIII UniProtKB/TrEMBL
NCBI Gene CA8 ENTREZGENE
PANTHER PTHR18952 UniProtKB/TrEMBL
Pfam Carb_anhydrase UniProtKB/TrEMBL
PROSITE ALPHA_CA_1 UniProtKB/TrEMBL
  ALPHA_CA_2 UniProtKB/TrEMBL
SMART Carb_anhydrase UniProtKB/TrEMBL
Superfamily-SCOP SSF51069 UniProtKB/TrEMBL
UniProt A0A287BFY8_PIG UniProtKB/TrEMBL
  A0A4X1SKE8_PIG UniProtKB/TrEMBL
  A0A4X1SLG9_PIG UniProtKB/TrEMBL
  A0A4X1SLL5_PIG UniProtKB/TrEMBL
  F1RT86_PIG UniProtKB/TrEMBL
VGNC ID VGNC:86105 ENTREZGENE