GEMIN4 (gem nuclear organelle associated protein 4) - Rat Genome Database

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Gene: GEMIN4 (gem nuclear organelle associated protein 4) Sus scrofa
Analyze
Symbol: GEMIN4
Name: gem nuclear organelle associated protein 4
RGD ID: 13859150
Description: ENCODES a protein that exhibits ribonucleoprotein complex binding (inferred); INVOLVED IN rRNA processing (inferred); spliceosomal snRNP assembly (inferred); ASSOCIATED WITH alcohol dependence (ortholog); cataract (ortholog); Developmental Disabilities (ortholog); FOUND IN SMN complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: gem-associated protein 4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1247,087,487 - 47,116,698 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11247,109,358 - 47,116,699 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21249,273,615 - 49,279,509 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
Cajal body  (IEA)
cytosol  (IEA)
nuclear body  (IEA)
nucleolus  (IEA)
SMN complex  (IBA,IEA,ISO)
SMN-Sm protein complex  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
GEMIN4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1247,087,487 - 47,116,698 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11247,109,358 - 47,116,699 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21249,273,615 - 49,279,509 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GEMIN4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3817744,421 - 754,410 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl17744,421 - 753,999 (-)EnsemblGRCh38hg38GRCh38
GRCh3717647,661 - 655,504 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3617594,411 - 602,251 (-)NCBINCBI36Build 36hg18NCBI36
Build 3417594,608 - 602,150NCBI
Celera17659,753 - 667,593 (-)NCBICelera
Cytogenetic Map17p13.3NCBI
HuRef17558,632 - 566,471 (-)NCBIHuRef
CHM1_117656,458 - 664,298 (-)NCBICHM1_1
T2T-CHM13v2.017629,497 - 641,166 (-)NCBIT2T-CHM13v2.0
Gemin4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391176,101,397 - 76,108,398 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1176,101,397 - 76,108,490 (-)EnsemblGRCm39 Ensembl
GRCm381176,210,571 - 76,217,572 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1176,210,571 - 76,217,664 (-)EnsemblGRCm38mm10GRCm38
MGSCv371176,024,073 - 76,031,074 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361176,026,766 - 76,033,707 (-)NCBIMGSCv36mm8
Celera1183,723,252 - 83,730,248 (-)NCBICelera
Cytogenetic Map11B5NCBI
cM Map1145.92NCBI
Gemin4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81061,560,172 - 61,571,765 (-)NCBIGRCr8
mRatBN7.21061,062,420 - 61,073,529 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1061,066,421 - 61,095,898 (-)EnsemblmRatBN7.2 Ensembl
mRatBN7.2 Ensembl1061,066,425 - 61,073,431 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1065,708,812 - 65,715,820 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01065,214,260 - 65,221,268 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01060,684,732 - 60,691,739 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01064,364,808 - 64,375,885 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1064,368,809 - 64,375,816 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01063,637,644 - 63,647,807 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41063,564,269 - 63,571,193 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1060,081,811 - 60,088,818 (-)NCBICelera
Cytogenetic Map10q24NCBI
Gemin4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554812,294,406 - 2,301,297 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554812,294,406 - 2,301,297 (-)NCBIChiLan1.0ChiLan1.0
GEMIN4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2198,294,213 - 8,301,876 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11710,263,927 - 10,271,621 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v017713,806 - 721,374 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.117637,677 - 644,438 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl17637,677 - 644,438 (-)Ensemblpanpan1.1panPan2
GEMIN4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1945,040,318 - 45,046,277 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl945,040,033 - 45,046,092 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha944,190,822 - 44,196,804 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0945,858,797 - 45,864,780 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl945,858,463 - 45,864,780 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1944,637,245 - 44,643,218 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0944,930,946 - 44,936,932 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0945,009,478 - 45,015,461 (+)NCBIUU_Cfam_GSD_1.0
Gemin4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560244,155,394 - 44,162,238 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365387,004,175 - 7,043,459 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365387,033,354 - 7,040,178 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GEMIN4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.116494,882 - 501,634 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl16490,523 - 501,594 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605921,583,566 - 21,590,997 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gemin4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247863,532,273 - 3,564,750 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247863,555,179 - 3,564,750 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in GEMIN4
217 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium
Low 10 4 3 5 2 23 2 3 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000019382   ⟹   ENSSSCP00000034888
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1247,087,487 - 47,115,253 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000053086   ⟹   ENSSSCP00000056896
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1247,109,414 - 47,116,698 (+)Ensembl
RefSeq Acc Id: XM_003131811   ⟹   XP_003131859
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11247,109,358 - 47,116,699 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021067527   ⟹   XP_020923186
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11247,109,630 - 47,116,699 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_003131859   ⟸   XM_003131811
- Peptide Label: isoform X1
- UniProtKB: A0A287BKG3 (UniProtKB/TrEMBL),   A0A8D1AWP5 (UniProtKB/TrEMBL),   A0A8D0Y3I3 (UniProtKB/TrEMBL),   A0A8D1DN18 (UniProtKB/TrEMBL),   A0A8D1TSD9 (UniProtKB/TrEMBL),   A0A8D2A5Y0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020923186   ⟸   XM_021067527
- Peptide Label: isoform X2
- UniProtKB: A0A8D0V175 (UniProtKB/TrEMBL),   A0A286ZTB7 (UniProtKB/TrEMBL),   A0A8D0XVN7 (UniProtKB/TrEMBL),   A0A8D1DMR4 (UniProtKB/TrEMBL),   A0A8D1P8I4 (UniProtKB/TrEMBL),   A0A8D2A8T6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000034888   ⟸   ENSSSCT00000019382
RefSeq Acc Id: ENSSSCP00000056896   ⟸   ENSSSCT00000053086


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000017809 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015055974 UniProtKB/TrEMBL
  ENSSSCG00025073490 UniProtKB/TrEMBL
  ENSSSCG00030067154 UniProtKB/TrEMBL
  ENSSSCG00035066356 UniProtKB/TrEMBL
  ENSSSCG00040016894 UniProtKB/TrEMBL
  ENSSSCG00050018183 UniProtKB/TrEMBL
  ENSSSCG00055000577 UniProtKB/TrEMBL
  ENSSSCG00065076851 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000019382 ENTREZGENE
  ENSSSCT00000019382.5 UniProtKB/TrEMBL
  ENSSSCT00000053086 ENTREZGENE
  ENSSSCT00000053086.3 UniProtKB/TrEMBL
  ENSSSCT00015074624.1 UniProtKB/TrEMBL
  ENSSSCT00015074717.1 UniProtKB/TrEMBL
  ENSSSCT00025101156.1 UniProtKB/TrEMBL
  ENSSSCT00025101211.1 UniProtKB/TrEMBL
  ENSSSCT00025101310.1 UniProtKB/TrEMBL
  ENSSSCT00030093892.1 UniProtKB/TrEMBL
  ENSSSCT00030093918.1 UniProtKB/TrEMBL
  ENSSSCT00030093979.1 UniProtKB/TrEMBL
  ENSSSCT00035089370.1 UniProtKB/TrEMBL
  ENSSSCT00035089392.1 UniProtKB/TrEMBL
  ENSSSCT00040022744.1 UniProtKB/TrEMBL
  ENSSSCT00040022755.1 UniProtKB/TrEMBL
  ENSSSCT00050024664.1 UniProtKB/TrEMBL
  ENSSSCT00050024676.1 UniProtKB/TrEMBL
  ENSSSCT00050024688.1 UniProtKB/TrEMBL
  ENSSSCT00055000989.1 UniProtKB/TrEMBL
  ENSSSCT00055001005.1 UniProtKB/TrEMBL
  ENSSSCT00065106227.1 UniProtKB/TrEMBL
  ENSSSCT00065106237.1 UniProtKB/TrEMBL
InterPro GEMIN4 UniProtKB/TrEMBL
NCBI Gene GEMIN4 ENTREZGENE
PANTHER GEM-ASSOCIATED PROTEIN 4 UniProtKB/TrEMBL
  PTHR15571 UniProtKB/TrEMBL
UniProt A0A286ZTB7 ENTREZGENE, UniProtKB/TrEMBL
  A0A287BKG3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0V175 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0XVN7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0Y3I3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1AWP5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1DMR4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1DN18 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1P8I4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1TSD9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D2A5Y0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D2A8T6 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:88412 ENTREZGENE