CCR7 (C-C motif chemokine receptor 7) - Rat Genome Database

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Gene: CCR7 (C-C motif chemokine receptor 7) Sus scrofa
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Symbol: CCR7
Name: C-C motif chemokine receptor 7
RGD ID: 13851550
Description: ENCODES a protein that exhibits C-C chemokine receptor activity (inferred); C-C motif chemokine 19 receptor activity (inferred); C-C motif chemokine 21 receptor activity (inferred); INVOLVED IN chemotaxis (ortholog); homeostasis of number of cells (ortholog); immune response (ortholog); ASSOCIATED WITH adult T-cell leukemia/lymphoma (ortholog); aspergillosis (ortholog); asthma (ortholog); FOUND IN cell surface (inferred); external side of plasma membrane (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: C-C chemokine receptor type 7; chemokine (C-C motif) receptor 7; chemokine receptor 7
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1221,857,286 - 21,872,475 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11221,857,286 - 21,869,211 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21222,140,218 - 22,152,166 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap12p13-p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:14610357   PMID:14681463   PMID:17991150   PMID:22301074   PMID:23219903   PMID:30032202  


Genomics

Comparative Map Data
CCR7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1221,857,286 - 21,872,475 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11221,857,286 - 21,869,211 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21222,140,218 - 22,152,166 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap12p13-p11NCBI
CCR7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381740,553,769 - 40,565,472 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1740,553,769 - 40,565,472 (-)EnsemblGRCh38hg38GRCh38
GRCh371738,710,021 - 38,721,724 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361735,963,547 - 35,975,250 (-)NCBINCBI36Build 36hg18NCBI36
Build 341735,963,549 - 35,975,250NCBI
Celera1735,371,568 - 35,383,283 (-)NCBICelera
Cytogenetic Map17q21.2NCBI
HuRef1734,504,331 - 34,516,046 (-)NCBIHuRef
CHM1_11738,945,325 - 38,957,040 (-)NCBICHM1_1
T2T-CHM13v2.01741,418,143 - 41,429,846 (-)NCBIT2T-CHM13v2.0
Ccr7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391199,035,025 - 99,045,903 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1199,035,022 - 99,045,903 (-)EnsemblGRCm39 Ensembl
GRCm381199,144,199 - 99,155,077 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1199,144,196 - 99,155,077 (-)EnsemblGRCm38mm10GRCm38
MGSCv371199,005,513 - 99,016,391 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361198,960,289 - 98,971,166 (-)NCBIMGSCv36mm8
Celera11108,811,008 - 108,821,915 (-)NCBICelera
Cytogenetic Map11DNCBI
cM Map1162.92NCBI
Ccr7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81084,594,399 - 84,604,514 (-)NCBIGRCr8
mRatBN7.21084,098,193 - 84,108,309 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1084,097,381 - 84,108,309 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1089,042,085 - 89,052,200 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01088,540,204 - 88,550,320 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01083,932,752 - 83,942,875 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01087,057,335 - 87,067,444 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1087,057,136 - 87,067,456 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01086,852,458 - 86,863,401 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41087,925,093 - 87,936,325 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11087,938,657 - 87,950,682 (-)NCBI
Celera1082,839,231 - 82,849,207 (-)NCBICelera
Cytogenetic Map10q31NCBI
Ccr7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545115,086,119 - 15,095,561 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545115,086,119 - 15,101,862 (-)NCBIChiLan1.0ChiLan1.0
CCR7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21924,385,980 - 24,400,730 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11726,280,748 - 26,293,297 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01716,720,236 - 16,731,955 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11716,944,641 - 16,956,370 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1716,949,119 - 16,956,370 (+)Ensemblpanpan1.1panPan2
CCR7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1922,077,976 - 22,092,818 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl922,068,775 - 22,090,656 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha921,541,628 - 21,565,735 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0922,861,789 - 22,885,706 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl922,861,889 - 22,883,415 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1921,636,159 - 21,660,074 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0921,895,041 - 21,918,952 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0922,019,550 - 22,043,479 (+)NCBIUU_Cfam_GSD_1.0
Ccr7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560221,495,373 - 21,501,797 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649015,575,764 - 15,579,757 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649015,575,764 - 15,579,766 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CCR7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11665,620,632 - 65,632,394 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1665,620,665 - 65,632,984 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607736,502,507 - 36,514,242 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ccr7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247952,779,627 - 2,788,897 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247952,777,766 - 2,787,664 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CCR7
463 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system hemolymphoid system nervous system reproductive system respiratory system
High
Medium
Low 7 2 5 1 2
Below cutoff 1 1 1

Sequence


RefSeq Acc Id: ENSSSCT00000019014   ⟹   ENSSSCP00000018509
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1221,857,286 - 21,872,475 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000089620   ⟹   ENSSSCP00000060334
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1221,857,286 - 21,869,232 (+)Ensembl
RefSeq Acc Id: NM_001001532   ⟹   NP_001001532
RefSeq Status: VALIDATED
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11221,857,286 - 21,869,211 (+)NCBI
Sequence:
RefSeq Acc Id: NP_001001532   ⟸   NM_001001532
- Peptide Label: precursor
- UniProtKB: Q861S1 (UniProtKB/TrEMBL),   A0A8D1CVB1 (UniProtKB/TrEMBL),   F6PW18 (UniProtKB/TrEMBL),   A0A4X1UCA0 (UniProtKB/TrEMBL),   A0A8D1ML07 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000018509   ⟸   ENSSSCT00000019014
RefSeq Acc Id: ENSSSCP00000060334   ⟸   ENSSSCT00000089620

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000017466 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005033793 UniProtKB/TrEMBL
  ENSSSCG00030033395 UniProtKB/TrEMBL
  ENSSSCG00035043074 UniProtKB/TrEMBL
  ENSSSCG00050044425 UniProtKB/TrEMBL
  ENSSSCG00070015815 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000019014 ENTREZGENE
  ENSSSCT00000019014.4 UniProtKB/TrEMBL
  ENSSSCT00005053978.1 UniProtKB/TrEMBL
  ENSSSCT00030046235.1 UniProtKB/TrEMBL
  ENSSSCT00035057227.1 UniProtKB/TrEMBL
  ENSSSCT00050060500.1 UniProtKB/TrEMBL
  ENSSSCT00070031077.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro Chemokine_CCR7 UniProtKB/TrEMBL
  Chemokine_rcpt UniProtKB/TrEMBL
  GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
KEGG Report ssc:396663 UniProtKB/TrEMBL
NCBI Gene CCR7 ENTREZGENE
PANTHER C-C CHEMOKINE RECEPTOR TYPE 7 UniProtKB/TrEMBL
  CELL ADHESION MOLECULE UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/TrEMBL
PRINTS CCCHEMOKINER UniProtKB/TrEMBL
  CHEMOKINER7 UniProtKB/TrEMBL
  GPCRRHODOPSN UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A4X1UCA0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1CVB1 ENTREZGENE
  A0A8D1ML07 ENTREZGENE, UniProtKB/TrEMBL
  F6PW18 ENTREZGENE
  Q861S1 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A8D1CVB1 UniProtKB/TrEMBL
  F6PW18 UniProtKB/TrEMBL
VGNC ID VGNC:86372 ENTREZGENE