ALS2CL (ALS2 C-terminal like) - Rat Genome Database

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Gene: ALS2CL (ALS2 C-terminal like) Sus scrofa
Analyze
Symbol: ALS2CL
Name: ALS2 C-terminal like
RGD ID: 13850842
Description: ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); INVOLVED IN protein localization (ortholog); ASSOCIATED WITH genetic disease (ortholog); Progressive Microcephaly with Seizures and Cerebral and Cerebellar Atrophy (ortholog); schizophrenia (ortholog); FOUND IN cytoplasmic vesicle (inferred); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ALS2 C-terminal-like protein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1329,596,700 - 29,618,919 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11329,596,696 - 29,618,915 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21332,829,891 - 32,901,030 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA)
cytoplasmic vesicle  (IBA,IEA)

Molecular Function

References

Genomics

Comparative Map Data
ALS2CL
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1329,596,700 - 29,618,919 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11329,596,696 - 29,618,915 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21332,829,891 - 32,901,030 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ALS2CL
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38346,668,995 - 46,693,679 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl346,668,995 - 46,693,704 (-)EnsemblGRCh38hg38GRCh38
GRCh37346,710,485 - 46,735,169 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36346,685,683 - 46,710,175 (-)NCBINCBI36Build 36hg18NCBI36
Celera346,648,229 - 46,672,945 (-)NCBICelera
Cytogenetic Map3p21.31NCBI
HuRef346,753,355 - 46,778,070 (-)NCBIHuRef
CHM1_1346,660,601 - 46,685,310 (-)NCBICHM1_1
T2T-CHM13v2.0346,685,103 - 46,709,793 (-)NCBIT2T-CHM13v2.0
Als2cl
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399110,709,203 - 110,729,598 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9110,708,938 - 110,729,598 (+)EnsemblGRCm39 Ensembl
GRCm389110,880,120 - 110,900,530 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9110,879,870 - 110,900,530 (+)EnsemblGRCm38mm10GRCm38
MGSCv379110,782,678 - 110,803,034 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369110,724,990 - 110,745,340 (+)NCBIMGSCv36mm8
Celera9110,606,134 - 110,626,473 (+)NCBICelera
Cytogenetic Map9F2NCBI
cM Map960.79NCBI
Als2cl
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88119,746,498 - 119,762,824 (+)NCBIGRCr8
mRatBN7.28110,863,753 - 110,884,434 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8110,864,975 - 110,884,419 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.08119,156,081 - 119,176,680 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8119,160,731 - 119,174,830 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08118,494,443 - 118,515,055 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48115,269,448 - 115,287,976 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18115,288,197 - 115,306,337 (+)NCBI
Celera8110,146,276 - 110,166,876 (+)NCBICelera
Cytogenetic Map8q32NCBI
Als2cl
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495542025,440,641 - 25,455,872 (+)NCBIChiLan1.0ChiLan1.0
ALS2CL
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2246,626,013 - 46,649,108 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1346,630,748 - 46,653,872 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0346,568,200 - 46,591,331 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1347,671,265 - 47,695,772 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl347,671,286 - 47,695,772 (-)Ensemblpanpan1.1panPan2
ALS2CL
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12042,067,018 - 42,091,125 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2042,066,833 - 42,088,321 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2041,982,917 - 42,007,069 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02042,549,320 - 42,573,473 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2042,541,177 - 42,570,324 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12041,790,574 - 41,811,579 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02042,191,649 - 42,212,661 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02042,472,701 - 42,493,718 (+)NCBIUU_Cfam_GSD_1.0
Als2cl
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118200,956,940 - 200,976,633 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936596506,077 - 525,746 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936596506,088 - 525,576 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ALS2CL
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1228,093,439 - 8,116,940 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl228,091,528 - 8,110,881 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041159,033,261 - 159,058,130 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Als2cl
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473074,509,658 - 74,525,221 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ALS2CL
491 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 8 1 2 1 2 7 3 1
Low 2 2 1 3 16 2
Below cutoff 1 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000028505   ⟹   ENSSSCP00000024262
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1329,596,700 - 29,618,919 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000030929   ⟹   ENSSSCP00000025924
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1329,596,705 - 29,618,860 (-)Ensembl
RefSeq Acc Id: XM_021068644   ⟹   XP_020924303
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11329,596,696 - 29,618,915 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021068645   ⟹   XP_020924304
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11329,596,696 - 29,618,871 (-)NCBI
Sequence:
RefSeq Acc Id: XR_002337512
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11329,596,696 - 29,618,915 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020924303   ⟸   XM_021068644
- Peptide Label: isoform X1
- UniProtKB: A0A8D1C5Y0 (UniProtKB/TrEMBL),   I3LJK1 (UniProtKB/TrEMBL),   A0A480WVB9 (UniProtKB/TrEMBL),   A0A8D0ZUD8 (UniProtKB/TrEMBL),   A0A8D1E2J1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020924304   ⟸   XM_021068645
- Peptide Label: isoform X2
- UniProtKB: A0A480WVB9 (UniProtKB/TrEMBL),   A0A8D0ZUD8 (UniProtKB/TrEMBL),   A0A8D1E2J1 (UniProtKB/TrEMBL),   A0A8D1TJU6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000025924   ⟸   ENSSSCT00000030929
RefSeq Acc Id: ENSSSCP00000024262   ⟸   ENSSSCT00000028505
Protein Domains
VPS9


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000021997 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015018502 UniProtKB/TrEMBL
  ENSSSCG00025055282 UniProtKB/TrEMBL
  ENSSSCG00030033115 UniProtKB/TrEMBL
  ENSSSCG00035038877 UniProtKB/TrEMBL
  ENSSSCG00040026422 UniProtKB/TrEMBL
  ENSSSCG00045014745 UniProtKB/TrEMBL
  ENSSSCG00050056647 UniProtKB/TrEMBL
  ENSSSCG00055008903 UniProtKB/TrEMBL
  ENSSSCG00060008459 UniProtKB/TrEMBL
  ENSSSCG00065035451 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000028505 ENTREZGENE
  ENSSSCT00000028505.2 UniProtKB/TrEMBL
  ENSSSCT00000030929.3 UniProtKB/TrEMBL
  ENSSSCT00015024559.1 UniProtKB/TrEMBL
  ENSSSCT00015024668.1 UniProtKB/TrEMBL
  ENSSSCT00025075681.1 UniProtKB/TrEMBL
  ENSSSCT00025076132.1 UniProtKB/TrEMBL
  ENSSSCT00025076416.1 UniProtKB/TrEMBL
  ENSSSCT00030045826.1 UniProtKB/TrEMBL
  ENSSSCT00030045931.1 UniProtKB/TrEMBL
  ENSSSCT00035051602.1 UniProtKB/TrEMBL
  ENSSSCT00035051623.1 UniProtKB/TrEMBL
  ENSSSCT00035051630.1 UniProtKB/TrEMBL
  ENSSSCT00040035374.1 UniProtKB/TrEMBL
  ENSSSCT00040035480.1 UniProtKB/TrEMBL
  ENSSSCT00045025281.1 UniProtKB/TrEMBL
  ENSSSCT00045025383.1 UniProtKB/TrEMBL
  ENSSSCT00045025528.1 UniProtKB/TrEMBL
  ENSSSCT00050077228.1 UniProtKB/TrEMBL
  ENSSSCT00055017426.1 UniProtKB/TrEMBL
  ENSSSCT00055017609.1 UniProtKB/TrEMBL
  ENSSSCT00055017764.1 UniProtKB/TrEMBL
  ENSSSCT00060010840.1 UniProtKB/TrEMBL
  ENSSSCT00060010848.1 UniProtKB/TrEMBL
  ENSSSCT00065048290.1 UniProtKB/TrEMBL
  ENSSSCT00065048303.1 UniProtKB/TrEMBL
  ENSSSCT00065048310.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1050.80 UniProtKB/TrEMBL
  1.20.900.10 UniProtKB/TrEMBL
  Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain UniProtKB/TrEMBL
InterPro DBL_dom_sf UniProtKB/TrEMBL
  MORN UniProtKB/TrEMBL
  VPS9 UniProtKB/TrEMBL
  VPS9_dom_sf UniProtKB/TrEMBL
NCBI Gene ALS2CL ENTREZGENE
PANTHER ALS2 C-TERMINAL-LIKE PROTEIN UniProtKB/TrEMBL
  ALSIN HOMOLOG UniProtKB/TrEMBL
Pfam MORN UniProtKB/TrEMBL
  VPS9 UniProtKB/TrEMBL
PROSITE VPS9 UniProtKB/TrEMBL
SMART MORN UniProtKB/TrEMBL
Superfamily-SCOP Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain UniProtKB/TrEMBL
  SSF109993 UniProtKB/TrEMBL
  SSF48065 UniProtKB/TrEMBL
UniProt A0A480WVB9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0SKS7_PIG UniProtKB/TrEMBL
  A0A8D0ZRD6_PIG UniProtKB/TrEMBL
  A0A8D0ZUD8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1C5Y0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1CTX1_PIG UniProtKB/TrEMBL
  A0A8D1E2J1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1HK10_PIG UniProtKB/TrEMBL
  A0A8D1Q0Y7_PIG UniProtKB/TrEMBL
  A0A8D1TJU6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1YPD6_PIG UniProtKB/TrEMBL
  I3LJK1 ENTREZGENE, UniProtKB/TrEMBL
  I3LP98_PIG UniProtKB/TrEMBL
VGNC ID VGNC:85270 ENTREZGENE