TAFAZZIN (tafazzin, phospholipid-lysophospholipid transacylase) - Rat Genome Database

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Gene: TAFAZZIN (tafazzin, phospholipid-lysophospholipid transacylase) Sus scrofa
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Symbol: TAFAZZIN
Name: tafazzin, phospholipid-lysophospholipid transacylase
RGD ID: 13844845
Description: ENCODES a protein that exhibits transferase activity, transferring acyl groups (inferred); INVOLVED IN cardiac muscle contraction (ortholog); cardiac muscle tissue development (ortholog); cardiolipin biosynthetic process (ortholog); PARTICIPATES IN cardiolipin metabolic pathway; ASSOCIATED WITH adrenoleukodystrophy (ortholog); autistic disorder (ortholog); Barth syndrome (ortholog); FOUND IN mitochondrial inner membrane (ortholog); mitochondrial outer membrane (ortholog); mitochondrion (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: TAZ
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX124,940,031 - 124,947,241 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X124,940,036 - 124,946,275 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:14681463   PMID:17145712  


Genomics

Comparative Map Data
TAFAZZIN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX124,940,031 - 124,947,241 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X124,940,036 - 124,946,275 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
TAFAZZIN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 EnsemblX154,411,524 - 154,421,726 (+)EnsemblGRCh38hg38GRCh38
GRCh38X154,411,539 - 154,421,726 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X153,639,875 - 153,650,065 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X153,293,071 - 153,303,259 (+)NCBINCBI36hg18NCBI36
Build 34X153,160,723 - 153,170,908NCBI
CeleraX153,800,935 - 153,811,119 (+)NCBI
Cytogenetic MapXq28NCBI
HuRefX142,217,267 - 142,227,597 (+)NCBIHuRef
CHM1_1X153,551,502 - 153,561,710 (+)NCBICHM1_1
Taz
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X73,325,498 - 73,340,182 (+)NCBIGRCm39mm39
GRCm39 EnsemblX73,325,518 - 73,333,757 (+)Ensembl
GRCm38X74,281,900 - 74,295,319 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX74,281,912 - 74,290,151 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X71,528,036 - 71,535,490 (+)NCBIGRCm37mm9NCBIm37
MGSCv36X70,535,482 - 70,542,868 (+)NCBImm8
CeleraX65,536,488 - 65,543,942 (+)NCBICelera
Cytogenetic MapXA7.3NCBI
cM MapX37.95NCBI
Tafazzin
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X152,065,539 - 152,076,178 (+)NCBI
Rnor_6.0 EnsemblX156,421,009 - 156,428,593 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0X156,421,006 - 156,429,461 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01152,161,153 - 152,169,569 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X160,319,389 - 160,326,974 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1135,822,755 - 135,830,340 (-)NCBICelera
Cytogenetic MapXq37NCBI
Tafazzin
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955580915,188 - 922,791 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955580915,668 - 921,703 (+)NCBIChiLan1.0ChiLan1.0
TAFAZZIN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1X153,725,299 - 153,734,046 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX153,725,294 - 153,734,046 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0X143,853,054 - 143,863,491 (+)NCBIMhudiblu_PPA_v0panPan3
TAFAZZIN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X122,111,608 - 122,125,714 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX122,111,434 - 122,125,506 (+)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.0X125,253,464 - 125,267,405 (+)NCBI
UMICH_Zoey_3.1X121,022,538 - 121,036,427 (+)NCBI
UNSW_CanFamBas_1.0X123,537,418 - 123,551,342 (+)NCBI
UU_Cfam_GSD_1.0X123,299,313 - 123,313,250 (+)NCBI
Tafazzin
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X119,422,492 - 119,431,185 (+)NCBI
SpeTri2.0NW_0049368091,160,265 - 1,168,956 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TAFAZZIN
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366606566,638,292 - 66,648,540 (+)NCBI
Tafazzin
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624946871,618 - 885,331 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 1
Low 10 4 3 4 2 23 2 3 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000060424   ⟹   ENSSSCP00000054012
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 EnsemblX124,940,031 - 124,947,241 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000066026   ⟹   ENSSSCP00000058225
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 EnsemblX124,940,031 - 124,947,241 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000080606   ⟹   ENSSSCP00000063890
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 EnsemblX124,940,034 - 124,946,272 (+)Ensembl
RefSeq Acc Id: XM_021080760   ⟹   XP_020936419
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1X124,940,036 - 124,946,275 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021080761   ⟹   XP_020936420
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1X124,940,036 - 124,946,275 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_020936419 (Get FASTA)   NCBI Sequence Viewer  
  XP_020936420 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_020936420   ⟸   XM_021080761
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_020936419   ⟸   XM_021080760
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSSSCP00000063890   ⟸   ENSSSCT00000080606
RefSeq Acc Id: ENSSSCP00000054012   ⟸   ENSSSCT00000060424
RefSeq Acc Id: ENSSSCP00000058225   ⟸   ENSSSCT00000066026
Protein Domains
PlsC


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000039655 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000054012 UniProtKB/TrEMBL
  ENSSSCP00000058225 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000063890 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000060424 UniProtKB/TrEMBL
  ENSSSCT00000066026 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000080606 ENTREZGENE, UniProtKB/TrEMBL
InterPro Plipid/glycerol_acylTrfase UniProtKB/TrEMBL
  Tafazzin UniProtKB/TrEMBL
NCBI Gene TAZ ENTREZGENE
PANTHER PTHR12497 UniProtKB/TrEMBL
Pfam Acyltransferase UniProtKB/TrEMBL
PRINTS TAFAZZIN UniProtKB/TrEMBL
SMART PlsC UniProtKB/TrEMBL
UniProt A0A287BD42_PIG UniProtKB/TrEMBL
  A0A287BNY4_PIG UniProtKB/TrEMBL
  A0A5G2R055_PIG UniProtKB/TrEMBL
VGNC ID VGNC:93756 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-15 TAFAZZIN  tafazzin, phospholipid-lysophospholipid transacylase  TAZ  tafazzin  Symbol and/or name change 19259463 PROVISIONAL