Rnaseh2b (ribonuclease H2, subunit B) - Rat Genome Database

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Gene: Rnaseh2b (ribonuclease H2, subunit B) Rattus norvegicus
Analyze
Symbol: Rnaseh2b
Name: ribonuclease H2, subunit B
RGD ID: 1359710
Description: Predicted to be involved in RNA catabolic process. Predicted to act upstream of or within several processes, including in utero embryonic development; positive regulation of fibroblast proliferation; and regulation of cell cycle phase transition. Predicted to be part of ribonuclease H2 complex. Predicted to be active in nucleoplasm. Human ortholog(s) of this gene implicated in Aicardi-Goutieres syndrome. Orthologous to human RNASEH2B (ribonuclease H2 subunit B); PARTICIPATES IN DNA replication pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; cobalt dichloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: MGC94780; ribonuclease H2 subunit B; ribonuclease HI subunit B; RNase H2 subunit B; similar to hypothetical protein FLJ11712
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81540,717,252 - 40,770,826 (+)NCBIGRCr8
mRatBN7.21536,541,200 - 36,592,016 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1536,541,218 - 36,584,118 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1538,417,594 - 38,460,476 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01539,568,229 - 39,611,111 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01538,001,910 - 38,044,798 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01545,422,010 - 45,472,792 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1545,422,010 - 45,464,892 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01549,197,404 - 49,248,205 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41541,554,754 - 41,597,638 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11541,570,453 - 41,613,336 (+)NCBI
Celera1536,231,039 - 36,273,907 (+)NCBICelera
Cytogenetic Map15p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleoplasm  (IBA,IEA,ISO)
ribonuclease H2 complex  (IBA,IEA,ISO,ISS)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:15489334   PMID:19923215   PMID:21177858   PMID:22802351  


Genomics

Comparative Map Data
Rnaseh2b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81540,717,252 - 40,770,826 (+)NCBIGRCr8
mRatBN7.21536,541,200 - 36,592,016 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1536,541,218 - 36,584,118 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1538,417,594 - 38,460,476 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01539,568,229 - 39,611,111 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01538,001,910 - 38,044,798 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01545,422,010 - 45,472,792 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1545,422,010 - 45,464,892 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01549,197,404 - 49,248,205 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41541,554,754 - 41,597,638 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11541,570,453 - 41,613,336 (+)NCBI
Celera1536,231,039 - 36,273,907 (+)NCBICelera
Cytogenetic Map15p12NCBI
RNASEH2B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381350,909,678 - 50,970,460 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1350,909,747 - 51,024,120 (+)EnsemblGRCh38hg38GRCh38
GRCh371351,483,814 - 51,544,596 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361350,381,928 - 50,428,901 (+)NCBINCBI36Build 36hg18NCBI36
Celera1332,532,888 - 32,593,597 (+)NCBICelera
Cytogenetic Map13q14.3NCBI
HuRef1332,272,725 - 32,333,508 (+)NCBIHuRef
CHM1_11351,451,357 - 51,512,138 (+)NCBICHM1_1
T2T-CHM13v2.01350,124,630 - 50,185,409 (+)NCBIT2T-CHM13v2.0
Rnaseh2b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391462,569,517 - 62,610,445 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1462,530,038 - 62,610,441 (+)EnsemblGRCm39 Ensembl
GRCm381462,332,068 - 62,372,996 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1462,292,589 - 62,372,992 (+)EnsemblGRCm38mm10GRCm38
MGSCv371462,950,942 - 62,991,829 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361461,286,215 - 61,327,102 (+)NCBIMGSCv36mm8
Celera1460,101,639 - 60,143,101 (+)NCBICelera
Cytogenetic Map14D1NCBI
cM Map1433.19NCBI
Rnaseh2b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554314,291,688 - 4,351,178 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554314,291,687 - 4,368,169 (+)NCBIChiLan1.0ChiLan1.0
RNASEH2B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21452,348,075 - 52,411,842 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11350,991,902 - 51,055,679 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01332,047,830 - 32,108,573 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11350,804,013 - 50,839,440 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1350,795,701 - 50,852,909 (+)Ensemblpanpan1.1panPan2
RNASEH2B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.122944,399 - 1,010,479 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl22931,751 - 991,223 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha22974,899 - 1,043,575 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.022933,922 - 992,941 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl22910,307 - 992,878 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.122855,278 - 913,961 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.022894,348 - 961,862 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.022922,842 - 981,538 (-)NCBIUU_Cfam_GSD_1.0
Rnaseh2b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945160,307,255 - 160,355,963 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365653,791,329 - 3,840,016 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365653,791,305 - 3,839,991 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RNASEH2B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1116,825,128 - 16,911,969 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11116,825,799 - 16,911,959 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
RNASEH2B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1328,791,490 - 28,856,542 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl328,791,748 - 28,841,733 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605714,998,872 - 15,066,688 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rnaseh2b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247483,246,707 - 3,339,443 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rnaseh2b
274 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:237
Count of miRNA genes:161
Interacting mature miRNAs:173
Transcripts:ENSRNOT00000012231
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
731170Pur3Proteinuria QTL 32.30.0005urine protein amount (VT:0005160)urine protein excretion rate (CMO:0000759)15141686771Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15142356671Rat
2298549Neuinf12Neuroinflammation QTL 123.5nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)15155302115Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1530632945306329Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15226636846921453Rat
1582251Gluco24Glucose level QTL 243.20.0008blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)15553075650530756Rat
631273Lecl2Lens clarity QTL 20.001lens clarity trait (VT:0001304)age of onset/diagnosis of cataract (CMO:0001584)151059608955596089Rat
2300167Bmd63Bone mineral density QTL 635.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
2300173Bmd62Bone mineral density QTL 6212.80.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
2293688Bss29Bone structure and strength QTL 295.310.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)151111114256111142Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151249614165205939Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151672552880672115Rat
1331729Rf42Renal function QTL 423.071kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)151736289773690657Rat
2324620Coatc3Coat color QTL 3coat/hair pigmentation trait (VT:0010463)pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)151985656646187442Rat
10054130Srcrt8Stress Responsive Cort QTL 82.180.0085blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)152211793367117933Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)152280624098288169Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)152280624098288169Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)152280624098288169Rat
1582214Stl21Serum triglyceride level QTL 213.10.022blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)152803066582262678Rat
1582227Gluco30Glucose level QTL 303.60.0003blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)152803066582262678Rat
1582228Epfw3Epididymal fat weight QTL 34.10.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)152803066582262678Rat
1582242Gluco28Glucose level QTL 283.30.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)152803066582262678Rat
1582244Bw79Body weight QTL 7940.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)152803066582262678Rat
2293691Bmd37Bone mineral density QTL 376.60.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)153361105871477291Rat
2293686Bmd36Bone mineral density QTL 367.40.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)153361105871477291Rat
1598828Glom14Glomerulus QTL 142.5kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)153405413979054139Rat

Markers in Region
BI286337  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21536,583,853 - 36,584,013 (+)MAPPERmRatBN7.2
Rnor_6.01545,464,630 - 45,464,789NCBIRnor6.0
Rnor_5.01549,240,043 - 49,240,202UniSTSRnor5.0
RGSC_v3.41541,597,374 - 41,597,533UniSTSRGSC3.4
Celera1536,273,643 - 36,273,802UniSTS
RH 3.4 Map15213.8UniSTS
Cytogenetic Map15p12UniSTS
BE109248  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21536,572,831 - 36,573,031 (+)MAPPERmRatBN7.2
Rnor_6.01545,453,608 - 45,453,807NCBIRnor6.0
Rnor_5.01549,229,028 - 49,229,227UniSTSRnor5.0
RGSC_v3.41541,586,352 - 41,586,551UniSTSRGSC3.4
Celera1536,262,621 - 36,262,820UniSTS
RH 3.4 Map15255.0UniSTS
Cytogenetic Map15p12UniSTS
BI274165  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21536,583,684 - 36,583,835 (+)MAPPERmRatBN7.2
Rnor_6.01545,464,461 - 45,464,611NCBIRnor6.0
Rnor_5.01549,239,874 - 49,240,024UniSTSRnor5.0
RGSC_v3.41541,597,205 - 41,597,355UniSTSRGSC3.4
Celera1536,273,474 - 36,273,624UniSTS
RH 3.4 Map15253.0UniSTS
Cytogenetic Map15p12UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 28 47 31 19 31 2 3 68 35 34 11 2
Low 15 10 10 10 6 8 6 7 6
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001007007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008770762 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008770764 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008770765 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039093505 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039093506 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039093507 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039093508 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039093509 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274416 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274417 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274419 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274420 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274421 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC133824 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC083791 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474023 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220108 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000012231   ⟹   ENSRNOP00000012231
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1536,541,218 - 36,584,118 (+)Ensembl
Rnor_6.0 Ensembl1545,422,010 - 45,464,892 (+)Ensembl
RefSeq Acc Id: NM_001007007   ⟹   NP_001007008
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81540,717,259 - 40,760,143 (+)NCBI
mRatBN7.21536,541,233 - 36,584,118 (+)NCBI
Rnor_6.01545,422,010 - 45,464,894 (+)NCBI
Rnor_5.01549,197,404 - 49,248,205 (+)NCBI
RGSC_v3.41541,554,754 - 41,597,638 (+)RGD
Celera1536,231,039 - 36,273,907 (+)RGD
Sequence:
RefSeq Acc Id: XM_008770762   ⟹   XP_008768984
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81540,727,272 - 40,760,143 (+)NCBI
mRatBN7.21536,551,263 - 36,584,118 (+)NCBI
Rnor_6.01545,430,110 - 45,464,894 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008770764   ⟹   XP_008768986
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81540,727,259 - 40,760,143 (+)NCBI
mRatBN7.21536,551,250 - 36,584,118 (+)NCBI
Rnor_6.01545,430,108 - 45,464,894 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008770765   ⟹   XP_008768987
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81540,727,267 - 40,770,826 (+)NCBI
mRatBN7.21536,551,259 - 36,592,016 (+)NCBI
Rnor_6.01545,430,109 - 45,472,792 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039093505   ⟹   XP_038949433
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81540,727,245 - 40,760,143 (+)NCBI
mRatBN7.21536,551,235 - 36,584,118 (+)NCBI
RefSeq Acc Id: XM_039093506   ⟹   XP_038949434
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81540,717,252 - 40,760,143 (+)NCBI
mRatBN7.21536,541,200 - 36,584,118 (+)NCBI
RefSeq Acc Id: XM_039093507   ⟹   XP_038949435
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81540,727,267 - 40,770,826 (+)NCBI
mRatBN7.21536,551,259 - 36,592,016 (+)NCBI
RefSeq Acc Id: XM_039093508   ⟹   XP_038949436
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81540,727,228 - 40,770,826 (+)NCBI
mRatBN7.21536,551,226 - 36,592,016 (+)NCBI
RefSeq Acc Id: XM_039093509   ⟹   XP_038949437
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81540,728,725 - 40,760,143 (+)NCBI
mRatBN7.21536,552,699 - 36,584,118 (+)NCBI
RefSeq Acc Id: XM_063274416   ⟹   XP_063130486
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81540,717,258 - 40,760,143 (+)NCBI
RefSeq Acc Id: XM_063274417   ⟹   XP_063130487
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81540,717,258 - 40,760,143 (+)NCBI
RefSeq Acc Id: XM_063274419   ⟹   XP_063130489
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81540,717,258 - 40,770,826 (+)NCBI
RefSeq Acc Id: XM_063274420   ⟹   XP_063130490
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81540,717,258 - 40,770,826 (+)NCBI
RefSeq Acc Id: XM_063274421   ⟹   XP_063130491
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81540,717,252 - 40,770,826 (+)NCBI
RefSeq Acc Id: NP_001007008   ⟸   NM_001007007
- UniProtKB: Q5XI96 (UniProtKB/Swiss-Prot),   A6K6C8 (UniProtKB/TrEMBL),   A0A8L2Q5D7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008768986   ⟸   XM_008770764
- Peptide Label: isoform X6
- UniProtKB: A0A8L2Q5D7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008768987   ⟸   XM_008770765
- Peptide Label: isoform X8
- UniProtKB: A6K6C9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008768984   ⟸   XM_008770762
- Peptide Label: isoform X1
- UniProtKB: A0A8L2Q5D7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000012231   ⟸   ENSRNOT00000012231
RefSeq Acc Id: XP_038949434   ⟸   XM_039093506
- Peptide Label: isoform X4
- UniProtKB: A0A8L2Q5D7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038949436   ⟸   XM_039093508
- Peptide Label: isoform X10
- UniProtKB: A6K6C9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038949433   ⟸   XM_039093505
- Peptide Label: isoform X2
- UniProtKB: A0A8L2Q5D7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038949435   ⟸   XM_039093507
- Peptide Label: isoform X5
- UniProtKB: A0A8L2Q5D7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038949437   ⟸   XM_039093509
- Peptide Label: isoform X13
RefSeq Acc Id: XP_063130491   ⟸   XM_063274421
- Peptide Label: isoform X12
RefSeq Acc Id: XP_063130489   ⟸   XM_063274419
- Peptide Label: isoform X9
RefSeq Acc Id: XP_063130490   ⟸   XM_063274420
- Peptide Label: isoform X11
RefSeq Acc Id: XP_063130487   ⟸   XM_063274417
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063130486   ⟸   XM_063274416
- Peptide Label: isoform X3
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5XI96-F1-model_v2 AlphaFold Q5XI96 1-307 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699767
Promoter ID:EPDNEW_R10291
Type:multiple initiation site
Name:Rnaseh2b_1
Description:ribonuclease H2, subunit B
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01545,421,998 - 45,422,058EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1359710 AgrOrtholog
BioCyc Gene G2FUF-13463 BioCyc
Ensembl Genes ENSRNOG00000009192 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00055012934 UniProtKB/Swiss-Prot
  ENSRNOG00060016703 UniProtKB/Swiss-Prot
  ENSRNOG00065031131 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000012231 ENTREZGENE
  ENSRNOT00000012231.5 UniProtKB/TrEMBL
  ENSRNOT00055022150 UniProtKB/Swiss-Prot
  ENSRNOT00060028577 UniProtKB/Swiss-Prot
  ENSRNOT00065053666 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.20.120 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.20.25.530 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7106440 IMAGE-MGC_LOAD
InterPro RNase_H2_suB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RNase_H2_suB_wHTH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rnh202_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:361056 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:94780 IMAGE-MGC_LOAD
NCBI Gene 361056 ENTREZGENE
PANTHER PTHR13383 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RIBONUCLEASE H2 SUBUNIT B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam RNase_H2-Ydr279 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ydr279_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Rnaseh2b PhenoGen
RatGTEx ENSRNOG00000009192 RatGTEx
  ENSRNOG00055012934 RatGTEx
  ENSRNOG00060016703 RatGTEx
  ENSRNOG00065031131 RatGTEx
UniProt A0A8L2Q5D7 ENTREZGENE, UniProtKB/TrEMBL
  A6K6C8 ENTREZGENE, UniProtKB/TrEMBL
  A6K6C9 ENTREZGENE, UniProtKB/TrEMBL
  Q5XI96 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-06 Rnaseh2b  ribonuclease H2, subunit B  MGC94780  similar to hypothetical protein FLJ11712  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-07-29 MGC94780  similar to hypothetical protein FLJ11712      Symbol and Name status set to provisional 70820 PROVISIONAL