Imported Disease Annotations - CTDTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Aicardi-Goutieres syndrome | | ISO | RNASEH2B (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | | |
|
Imported Disease Annotations - CTDTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Aicardi-Goutieres syndrome | | ISO | RNASEH2B (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | | |
|
|
|
|
|
|
# | Reference Title | Reference Citation |
1. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
2. | OMIM Disease Annotation Pipeline | OMIM Disease Annotation Pipeline |
3. | KEGG Annotation Import Pipeline | Pipeline to import KEGG annotations from KEGG into RGD |
4. | GOA pipeline | RGD automated data pipeline |
5. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
6. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
7. | Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. | Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11. |
Rnaseh2b (Rattus norvegicus - Norway rat) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
RNASEH2B (Homo sapiens - human) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Rnaseh2b (Mus musculus - house mouse) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Rnaseh2b (Chinchilla lanigera - long-tailed chinchilla) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
RNASEH2B (Pan paniscus - bonobo/pygmy chimpanzee) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
RNASEH2B (Canis lupus familiaris - dog) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Rnaseh2b (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
RNASEH2B (Sus scrofa - pig) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
RNASEH2B (Chlorocebus sabaeus - green monkey) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Rnaseh2b (Heterocephalus glaber - naked mole-rat) |
|
.
Variants in Rnaseh2b
274 total Variants |
The detailed report is available here: | Full Report | CSV | TAB | Printer | ||||
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
The following QTLs overlap with this region. | Full Report | CSV | TAB | Printer | Gviewer |
BI286337 |
|
||||||||||||||||||||||||||||||||||||||||
BE109248 |
|
||||||||||||||||||||||||||||||||||||||||
BI274165 |
|
alimentary part of gastrointestinal system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | appendage | |
High | |||||||||||||
Medium | 3 | 28 | 47 | 31 | 19 | 31 | 2 | 3 | 68 | 35 | 34 | 11 | 2 |
Low | 15 | 10 | 10 | 10 | 6 | 8 | 6 | 7 | 6 | ||||
Below cutoff |
RefSeq Transcripts | NM_001007007 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
XM_008770762 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_008770764 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_008770765 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039093505 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039093506 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039093507 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039093508 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039093509 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063274416 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063274417 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063274419 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063274420 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063274421 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
GenBank Nucleotide | AC133824 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
BC083791 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
CH474023 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
FQ220108 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
JAXUCZ010000015 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
RefSeq Acc Id: | ENSRNOT00000012231 ⟹ ENSRNOP00000012231 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
|
RefSeq Acc Id: | NM_001007007 ⟹ NP_001007008 | ||||||||||||||||||||||||||||
RefSeq Status: | PROVISIONAL | ||||||||||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||||||||||
Position: |
|
||||||||||||||||||||||||||||
Sequence: |
RefSeq Acc Id: | XM_008770762 ⟹ XP_008768984 | ||||||||||||||||
Type: | CODING | ||||||||||||||||
Position: |
|
||||||||||||||||
Sequence: |
RefSeq Acc Id: | XM_008770764 ⟹ XP_008768986 | ||||||||||||||||
Type: | CODING | ||||||||||||||||
Position: |
|
||||||||||||||||
Sequence: |
RefSeq Acc Id: | XM_008770765 ⟹ XP_008768987 | ||||||||||||||||
Type: | CODING | ||||||||||||||||
Position: |
|
||||||||||||||||
Sequence: |
RefSeq Acc Id: | XM_039093505 ⟹ XP_038949433 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
|
RefSeq Acc Id: | XM_039093506 ⟹ XP_038949434 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
|
RefSeq Acc Id: | XM_039093507 ⟹ XP_038949435 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
|
RefSeq Acc Id: | XM_039093508 ⟹ XP_038949436 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
|
RefSeq Acc Id: | XM_039093509 ⟹ XP_038949437 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
|
RefSeq Acc Id: | XM_063274416 ⟹ XP_063130486 | ||||||||
Type: | CODING | ||||||||
Position: |
|
RefSeq Acc Id: | XM_063274417 ⟹ XP_063130487 | ||||||||
Type: | CODING | ||||||||
Position: |
|
RefSeq Acc Id: | XM_063274419 ⟹ XP_063130489 | ||||||||
Type: | CODING | ||||||||
Position: |
|
RefSeq Acc Id: | XM_063274420 ⟹ XP_063130490 | ||||||||
Type: | CODING | ||||||||
Position: |
|
RefSeq Acc Id: | XM_063274421 ⟹ XP_063130491 | ||||||||
Type: | CODING | ||||||||
Position: |
|
Protein RefSeqs | NP_001007008 | (Get FASTA) | NCBI Sequence Viewer |
XP_008768984 | (Get FASTA) | NCBI Sequence Viewer | |
XP_008768986 | (Get FASTA) | NCBI Sequence Viewer | |
XP_008768987 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038949433 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038949434 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038949435 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038949436 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038949437 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063130486 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063130487 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063130489 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063130490 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063130491 | (Get FASTA) | NCBI Sequence Viewer | |
GenBank Protein | AAH83791 | (Get FASTA) | NCBI Sequence Viewer |
EDL85288 | (Get FASTA) | NCBI Sequence Viewer | |
EDL85289 | (Get FASTA) | NCBI Sequence Viewer | |
Ensembl Protein | ENSRNOP00000012231 | ||
ENSRNOP00000012231.5 | |||
ENSRNOP00055017991 | |||
ENSRNOP00060022987 | |||
ENSRNOP00065044114 | |||
GenBank Protein | Q5XI96 | (Get FASTA) | NCBI Sequence Viewer |
RefSeq Acc Id: | NP_001007008 ⟸ NM_001007007 |
- UniProtKB: | Q5XI96 (UniProtKB/Swiss-Prot), A6K6C8 (UniProtKB/TrEMBL), A0A8L2Q5D7 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_008768986 ⟸ XM_008770764 |
- Peptide Label: | isoform X6 |
- UniProtKB: | A0A8L2Q5D7 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_008768987 ⟸ XM_008770765 |
- Peptide Label: | isoform X8 |
- UniProtKB: | A6K6C9 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_008768984 ⟸ XM_008770762 |
- Peptide Label: | isoform X1 |
- UniProtKB: | A0A8L2Q5D7 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | ENSRNOP00000012231 ⟸ ENSRNOT00000012231 |
RefSeq Acc Id: | XP_038949434 ⟸ XM_039093506 |
- Peptide Label: | isoform X4 |
- UniProtKB: | A0A8L2Q5D7 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | XP_038949436 ⟸ XM_039093508 |
- Peptide Label: | isoform X10 |
- UniProtKB: | A6K6C9 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | XP_038949433 ⟸ XM_039093505 |
- Peptide Label: | isoform X2 |
- UniProtKB: | A0A8L2Q5D7 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | XP_038949435 ⟸ XM_039093507 |
- Peptide Label: | isoform X5 |
- UniProtKB: | A0A8L2Q5D7 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | XP_038949437 ⟸ XM_039093509 |
- Peptide Label: | isoform X13 |
RefSeq Acc Id: | XP_063130491 ⟸ XM_063274421 |
- Peptide Label: | isoform X12 |
RefSeq Acc Id: | XP_063130489 ⟸ XM_063274419 |
- Peptide Label: | isoform X9 |
RefSeq Acc Id: | XP_063130490 ⟸ XM_063274420 |
- Peptide Label: | isoform X11 |
RefSeq Acc Id: | XP_063130487 ⟸ XM_063274417 |
- Peptide Label: | isoform X7 |
RefSeq Acc Id: | XP_063130486 ⟸ XM_063274416 |
- Peptide Label: | isoform X3 |
Name | Modeler | Protein Id | AA Range | Protein Structure |
AF-Q5XI96-F1-model_v2 | AlphaFold | Q5XI96 | 1-307 | view protein structure |
eQTL | View at Phenogen | |
WGCNA | View at Phenogen | |
Tissue/Strain Expression | View at Phenogen |
RGD ID: | 13699767 | ||||||||
Promoter ID: | EPDNEW_R10291 | ||||||||
Type: | multiple initiation site | ||||||||
Name: | Rnaseh2b_1 | ||||||||
Description: | ribonuclease H2, subunit B | ||||||||
SO ACC ID: | SO:0000170 | ||||||||
Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
Experiment Methods: | Single-end sequencing. | ||||||||
Position: |
|
Database | Acc Id | Source(s) |
AGR Gene | RGD:1359710 | AgrOrtholog |
BioCyc Gene | G2FUF-13463 | BioCyc |
Ensembl Genes | ENSRNOG00000009192 | Ensembl, ENTREZGENE, UniProtKB/TrEMBL |
ENSRNOG00055012934 | UniProtKB/Swiss-Prot | |
ENSRNOG00060016703 | UniProtKB/Swiss-Prot | |
ENSRNOG00065031131 | UniProtKB/Swiss-Prot | |
Ensembl Transcript | ENSRNOT00000012231 | ENTREZGENE |
ENSRNOT00000012231.5 | UniProtKB/TrEMBL | |
ENSRNOT00055022150 | UniProtKB/Swiss-Prot | |
ENSRNOT00060028577 | UniProtKB/Swiss-Prot | |
ENSRNOT00065053666 | UniProtKB/Swiss-Prot | |
Gene3D-CATH | 1.10.20.120 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
2.20.25.530 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
IMAGE_CLONE | IMAGE:7106440 | IMAGE-MGC_LOAD |
InterPro | RNase_H2_suB | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
RNase_H2_suB_wHTH | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Rnh202_N | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
KEGG Report | rno:361056 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
MGC_CLONE | MGC:94780 | IMAGE-MGC_LOAD |
NCBI Gene | 361056 | ENTREZGENE |
PANTHER | PTHR13383 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
RIBONUCLEASE H2 SUBUNIT B | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Pfam | RNase_H2-Ydr279 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
Ydr279_N | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
PhenoGen | Rnaseh2b | PhenoGen |
RatGTEx | ENSRNOG00000009192 | RatGTEx |
ENSRNOG00055012934 | RatGTEx | |
ENSRNOG00060016703 | RatGTEx | |
ENSRNOG00065031131 | RatGTEx | |
UniProt | A0A8L2Q5D7 | ENTREZGENE, UniProtKB/TrEMBL |
A6K6C8 | ENTREZGENE, UniProtKB/TrEMBL | |
A6K6C9 | ENTREZGENE, UniProtKB/TrEMBL | |
Q5XI96 | ENTREZGENE, UniProtKB/Swiss-Prot |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
---|---|---|---|---|---|---|---|
2008-03-06 | Rnaseh2b | ribonuclease H2, subunit B | MGC94780 | similar to hypothetical protein FLJ11712 | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2005-07-29 | MGC94780 | similar to hypothetical protein FLJ11712 | Symbol and Name status set to provisional | 70820 | PROVISIONAL |