Qrsl1 (glutaminyl-tRNA amidotransferase subunit QRSL1) - Rat Genome Database

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Gene: Qrsl1 (glutaminyl-tRNA amidotransferase subunit QRSL1) Rattus norvegicus
Analyze
Symbol: Qrsl1
Name: glutaminyl-tRNA amidotransferase subunit QRSL1
RGD ID: 1359490
Description: Predicted to enable glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity. Predicted to be involved in glutaminyl-tRNAGln biosynthesis via transamidation and mitochondrial translation. Predicted to act upstream of or within regulation of protein stability. Predicted to be part of glutamyl-tRNA(Gln) amidotransferase complex. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 40. Orthologous to human QRSL1 (glutaminyl-tRNA amidotransferase subunit QRSL1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 4-amino-2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: glu-AdT subunit A; glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1; glutaminyl-tRNA synthase-like protein 1; glutamyl-tRNA(Gln) amidotransferase subunit A homolog; glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial; LOC309911; MGC105526; QRSL1, glutaminyl-tRNA amidotransferase subunit A; similar to glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22047,357,211 - 47,382,135 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2047,357,216 - 47,382,135 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2049,081,037 - 49,105,743 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.02048,730,907 - 48,755,617 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.02049,412,778 - 49,437,714 (-)NCBIRnor_WKY
Rnor_6.02048,855,839 - 48,881,112 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2048,855,914 - 48,881,119 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02050,498,355 - 50,523,543 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42047,793,416 - 47,818,351 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12047,822,112 - 47,847,048 (-)NCBI
Celera2052,611,574 - 52,635,840 (+)NCBICelera
Cytogenetic Map20q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:19805282   PMID:24579914  


Genomics

Comparative Map Data
Qrsl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22047,357,211 - 47,382,135 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2047,357,216 - 47,382,135 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2049,081,037 - 49,105,743 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.02048,730,907 - 48,755,617 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.02049,412,778 - 49,437,714 (-)NCBIRnor_WKY
Rnor_6.02048,855,839 - 48,881,112 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2048,855,914 - 48,881,119 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02050,498,355 - 50,523,543 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42047,793,416 - 47,818,351 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12047,822,112 - 47,847,048 (-)NCBI
Celera2052,611,574 - 52,635,840 (+)NCBICelera
Cytogenetic Map20q13NCBI
QRSL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386106,629,578 - 106,668,417 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl6106,629,578 - 106,668,417 (+)EnsemblGRCh38hg38GRCh38
GRCh376107,077,453 - 107,116,292 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366107,184,146 - 107,222,103 (+)NCBINCBI36Build 36hg18NCBI36
Build 346107,184,145 - 107,222,103NCBI
Celera6107,698,355 - 107,737,185 (+)NCBICelera
Cytogenetic Map6q21NCBI
HuRef6104,524,550 - 104,563,384 (+)NCBIHuRef
CHM1_16107,340,205 - 107,379,052 (+)NCBICHM1_1
T2T-CHM13v2.06107,806,065 - 107,844,870 (+)NCBIT2T-CHM13v2.0
Qrsl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391043,750,184 - 43,777,742 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1043,750,184 - 43,777,741 (-)EnsemblGRCm39 Ensembl
GRCm381043,874,188 - 43,901,742 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1043,874,188 - 43,901,745 (-)EnsemblGRCm38mm10GRCm38
MGSCv371043,593,996 - 43,621,542 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361043,562,501 - 43,590,154 (-)NCBIMGSCv36mm8
Celera1044,746,059 - 44,773,667 (-)NCBICelera
Cytogenetic Map10B2NCBI
Qrsl1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541131,950,828 - 31,981,468 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541131,950,727 - 31,981,522 (+)NCBIChiLan1.0ChiLan1.0
QRSL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.16108,315,270 - 108,353,505 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6108,315,270 - 108,353,505 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v06104,444,646 - 104,481,732 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
QRSL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11263,972,423 - 64,003,506 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1263,759,642 - 63,792,333 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01264,815,666 - 64,848,426 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1264,815,691 - 64,848,416 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11264,176,598 - 64,208,991 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01264,019,223 - 64,051,741 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01264,293,008 - 64,325,953 (+)NCBIUU_Cfam_GSD_1.0
Qrsl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494698,874,322 - 98,904,602 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365643,149,154 - 3,179,514 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
QRSL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl172,815,613 - 72,844,843 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1172,815,601 - 72,846,871 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2182,112,141 - 82,145,804 (+)NCBISscrofa10.2Sscrofa10.2susScr3
QRSL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11367,153,372 - 67,188,775 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1367,151,437 - 67,189,662 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604039,487,556 - 39,525,430 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Qrsl1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478015,628,678 - 15,664,651 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478015,629,167 - 15,664,787 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Position Markers
RH129971  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22047,361,550 - 47,362,228 (+)MAPPERmRatBN7.2
Rnor_6.02048,860,313 - 48,860,990NCBIRnor6.0
Rnor_5.02050,502,748 - 50,503,425UniSTSRnor5.0
RGSC_v3.42047,797,756 - 47,798,433UniSTSRGSC3.4
Celera2052,631,485 - 52,632,162UniSTS
RH 3.4 Map20495.42UniSTS
Cytogenetic Map20q13UniSTS
RH133719  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22047,357,281 - 47,357,492 (-)MAPPERmRatBN7.2
mRatBN7.22047,357,281 - 47,357,492 (+)MAPPERmRatBN7.2
Rnor_6.02048,856,044 - 48,856,254NCBIRnor6.0
Rnor_6.01134,697,493 - 34,697,703NCBIRnor6.0
Rnor_5.02050,498,479 - 50,498,689UniSTSRnor5.0
Rnor_5.01138,288,899 - 38,289,109UniSTSRnor5.0
RGSC_v3.42047,793,487 - 47,793,697UniSTSRGSC3.4
Celera2052,635,559 - 52,635,769UniSTS
RH 3.4 Map20494.82UniSTS
Cytogenetic Map11q11UniSTS
Cytogenetic Map20q13UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1598816Memor12Memory QTL 122.4exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)20260683647606836Rat
7411652Foco24Food consumption QTL 240.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)201175751554435887Rat
9590092Insglur9Insulin/glucose ratio QTL 918.380.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)201175751554435887Rat
4889610Pancm3Pancreatic morphology QTL 33.750.001pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)201761783247606836Rat
2317880Alcrsp25Alcohol response QTL 252.3response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)201769755054435887Rat
2303626Vencon10Ventilatory control QTL 100.001respiration trait (VT:0001943)respiration rate (CMO:0000289)201919072154435887Rat
2303578Gluco50Glucose level QTL 502blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)202510672254435887Rat
2303587Bw93Body weight QTL 9313body mass (VT:0001259)body weight (CMO:0000012)202510672254435887Rat
2300188Bmd68Bone mineral density QTL 686.40.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)202510672254435887Rat
1331747Hrtrt16Heart rate QTL 163.163heart pumping trait (VT:2000009)heart rate (CMO:0000002)202520973454435887Rat
1598869Memor6Memory QTL 63.1exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)202924438854435887Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:187
Count of miRNA genes:133
Interacting mature miRNAs:148
Transcripts:ENSRNOT00000018892
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 41 19 12 8 12 73 30 32
Low 3 2 38 29 11 29 8 11 1 5 9 11 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000018892   ⟹   ENSRNOP00000018891
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2047,357,216 - 47,382,135 (-)Ensembl
Rnor_6.0 Ensembl2048,855,914 - 48,881,119 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000101938   ⟹   ENSRNOP00000080547
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2047,357,216 - 47,377,299 (-)Ensembl
RefSeq Acc Id: NM_001014034   ⟹   NP_001014056
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22047,357,211 - 47,382,135 (-)NCBI
Rnor_6.02048,855,973 - 48,881,071 (-)NCBI
Rnor_5.02050,498,355 - 50,523,543 (-)NCBI
RGSC_v3.42047,793,416 - 47,818,351 (-)RGD
Celera2052,611,574 - 52,635,840 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001014056 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH89213 (Get FASTA)   NCBI Sequence Viewer  
  EDL99683 (Get FASTA)   NCBI Sequence Viewer  
  Q5FWT5 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001014056   ⟸   NM_001014034
- UniProtKB: Q5FWT5 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000018891   ⟸   ENSRNOT00000018892
RefSeq Acc Id: ENSRNOP00000080547   ⟸   ENSRNOT00000101938
Protein Domains
Amidase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5FWT5-F1-model_v2 AlphaFold Q5FWT5 1-525 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701680
Promoter ID:EPDNEW_R12204
Type:multiple initiation site
Name:Qrsl1_1
Description:glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02048,881,083 - 48,881,143EPDNEW

Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
Damaging Variants


Assembly: Rnor_6.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
20 48858220 48858221 T C snv CDR, CDS, ACI/EurMcwi (MCW), COP/CrCrl (MCW & UW), FHH/EurMcwi (MCW), FHL/EurMcwi (MCW), GH/OmrMcwi (MCW), SBH/Ygl (MCW), SBN/Ygl (MCW), SR/JrHsd (MCW), SS/JrHsdMcwi (MCW), ACI/EurMcwi (2019), ACI/N (2020), BN-Lx/CubMcwi (2019), BN/NHsdMcwi (2020), BN/NHsdMcwi (2019), BN/SsN (2020), BUF/N (2020), BXH2/CubMcwi (2020), BXH3/CubMcwi (2020), DA/OlaHsd (2019), F344/DuCrl (2019), F344/NCrl (2019), F344/Stm (2019), FHH/EurMcwi (2019), FXLE18/Stm (2020), GK/FarMcwi (2019), HXB2/IpcvMcwi (2019), HXB31/IpcvMcwi (2019), HXB4/IpcvMcwi (2020), LEXF11/Stm (2020), LEXF1A/Stm (2019), LEXF1C/Stm (2019), LEXF2B/Stm (2019), LEXF3/Stm (2020), LEXF4/Stm (2020), LE/Stm (2019), LH/MavRrrcAek (2020), LL/MavRrrcAek (2020), LN/MavRrrcAek (2020), LEXF10A/StmMcwi (2020), M520/NRrrcMcwi (2019), M520/N (2020), MR/N (2020), MWF/Hsd (2019), PVG/Seac (2019), SHRSP/A3NCrl (2019), SHR/OlalpcvMcwi (2019), SR/JrHsd (2020), SS/JrHsdMcwi (2019), WAG/RijCrl (2020), WKY/NCrl (2019), WKY/N (2020), WN/N (2020)
20 48858232 48858233 C G snv CDR, WN/N (2020), ACI/EurMcwi (2019), ACI/N (2020), BN-Lx/CubMcwi (2019), BN/NHsdMcwi (2020), BN/NHsdMcwi (2019), BN/SsN (2020), BUF/N (2020), BXH2/CubMcwi (2020), BXH3/CubMcwi (2020), DA/OlaHsd (2019), F344/DuCrl (2019), F344/NCrl (2019), F344/Stm (2019), FHH/EurMcwi (2019), FXLE18/Stm (2020), GK/FarMcwi (2019), HXB20/IpcvMcwi (2020), HXB2/IpcvMcwi (2019), HXB31/IpcvMcwi (2019), HXB4/IpcvMcwi (2020), LEXF11/Stm (2020), LEXF1A/Stm (2019), LEXF1C/Stm (2019), LEXF2B/Stm (2019), LEXF3/Stm (2020), LEXF4/Stm (2020), LE/Stm (2019), LH/MavRrrcAek (2020), LL/MavRrrcAek (2020), LN/MavRrrcAek (2020), LEXF10A/StmMcwi (2020), M520/NRrrcMcwi (2019), M520/N (2020), MR/N (2020), PVG/Seac (2019), SHRSP/A3NCrl (2019), SHR/OlalpcvMcwi (2019), SR/JrHsd (2020), SS/JrHsdMcwi (2019), WAG/RijCrl (2020), WKY/NCrl (2019), WKY/N (2020), CDS


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1359490 AgrOrtholog
BioCyc Gene G2FUF-3309 BioCyc
BioCyc Pathway CITRULBIO-PWY [L-citrulline biosynthesis] BioCyc
  GLUTAMINDEG-PWY [L-glutamine degradation I] BioCyc
  PWY-5921 [glutaminyl-tRNAgln biosynthesis via transamidation] BioCyc
Ensembl Genes ENSRNOG00000026049 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000018891 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000080547.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000018892 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000101938.1 UniProtKB/TrEMBL
Gene3D-CATH 3.90.1300.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7302358 IMAGE-MGC_LOAD
InterPro Amidase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Amidase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AS_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GatA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:309911 UniProtKB/Swiss-Prot
MGC_CLONE MGC:105526 IMAGE-MGC_LOAD
NCBI Gene 309911 ENTREZGENE
PANTHER PTHR11895 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Amidase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Qrsl1 PhenoGen
Superfamily-SCOP SSF75304 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGRFAMs gatA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5ZPV2_RAT UniProtKB/TrEMBL
  GATA_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-03 Qrsl1  glutaminyl-tRNA amidotransferase subunit QRSL1  Qrsl1  QRSL1, glutaminyl-tRNA amidotransferase subunit A  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2018-07-26 Qrsl1  QRSL1, glutaminyl-tRNA amidotransferase subunit A  Qrsl1  glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-11-17 Qrsl1  glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1  LOC309911  similar to glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1  Symbol and Name updated 1299863 APPROVED
2005-07-29 LOC309911  similar to glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1      Symbol and Name status set to provisional 70820 PROVISIONAL