Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | decreases expression | ISO | Ndrg3 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of NDRG3 mRNA | CTD | PMID:22206623 | 1-chloro-2,4-dinitrobenzene | affects binding | ISO | NDRG3 (Homo sapiens) | 6480464 | Dinitrochlorobenzene binds to NDRG3 protein | CTD | PMID:32991956 | 17beta-estradiol | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Estradiol] results in increased expression of NDRG3 mRNA | CTD | PMID:26496021 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Ndrg3 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of NDRG3 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of NDRG3 mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | NDRG3 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin affects the expression of NDRG3 mRNA | CTD | PMID:22574217 | 2-methylcholine | affects expression | ISO | NDRG3 (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of NDRG3 mRNA | CTD | PMID:21179406 | 4,4'-diaminodiphenylmethane | affects expression | ISO | Ndrg3 (Mus musculus) | 6480464 | 4 and 4'-diaminodiphenylmethane affects the expression of NDRG3 mRNA | CTD | PMID:18648102 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of NDRG3 mRNA | CTD | PMID:30047161 | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of NDRG3 mRNA | CTD | PMID:28959563 | all-trans-retinoic acid | decreases expression | ISO | NDRG3 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of NDRG3 mRNA | CTD | PMID:33167477 | aristolochic acid A | decreases expression | ISO | NDRG3 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of NDRG3 mRNA | CTD | PMID:33212167 | benzo[a]pyrene | increases methylation | ISO | NDRG3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of NDRG3 promoter | CTD | PMID:27901495 | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of NDRG3 mRNA | CTD | PMID:25181051 | bisphenol A | multiple interactions | ISO | NDRG3 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in decreased methylation of NDRG3 gene | CTD | PMID:31601247 | bisphenol A | increases expression | ISO | Ndrg3 (Mus musculus) | 6480464 | bisphenol A results in increased expression of NDRG3 mRNA | CTD | PMID:33221593 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of NDRG3 mRNA | CTD | PMID:29097150 | bisphenol A | decreases methylation | EXP | | 6480464 | bisphenol A results in decreased methylation of NDRG3 gene | CTD | PMID:28505145 | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Estradiol] results in increased expression of NDRG3 mRNA and [bisphenol A co-treated with Genistein] results in decreased methylation of NDRG3 gene | CTD | PMID:26496021 and PMID:28505145 | bortezomib | decreases expression | ISO | NDRG3 (Homo sapiens) | 6480464 | Bortezomib results in decreased expression of NDRG3 mRNA | CTD | PMID:20977926 | cadmium atom | multiple interactions | ISO | NDRG3 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of NDRG3 mRNA | CTD | PMID:35301059 | cadmium dichloride | multiple interactions | ISO | NDRG3 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of NDRG3 mRNA | CTD | PMID:35301059 | caffeine | affects phosphorylation | ISO | NDRG3 (Homo sapiens) | 6480464 | Caffeine affects the phosphorylation of NDRG3 protein | CTD | PMID:35688186 | cerium trichloride | increases expression | ISO | Ndrg3 (Mus musculus) | 6480464 | cerous chloride results in increased expression of NDRG3 mRNA | CTD | PMID:23573234 | cisplatin | decreases expression | ISO | NDRG3 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of NDRG3 mRNA | CTD | PMID:27594783 | cisplatin | increases expression | ISO | NDRG3 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of NDRG3 mRNA | CTD | PMID:27392435 | cisplatin | multiple interactions | ISO | NDRG3 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of NDRG3 mRNA | CTD | PMID:27392435 | cobalt dichloride | decreases expression | ISO | NDRG3 (Homo sapiens) | 6480464 | cobaltous chloride results in decreased expression of NDRG3 mRNA | CTD | PMID:19320972 | coumarin | increases phosphorylation | ISO | NDRG3 (Homo sapiens) | 6480464 | coumarin results in increased phosphorylation of NDRG3 protein | CTD | PMID:35688186 | Cuprizon | decreases expression | EXP | | 6480464 | Cuprizone results in decreased expression of NDRG3 mRNA | CTD | PMID:26577399 | cyclosporin A | decreases expression | ISO | NDRG3 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of NDRG3 mRNA | CTD | PMID:20106945 more ... | dorsomorphin | multiple interactions | ISO | NDRG3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NDRG3 mRNA | CTD | PMID:27188386 | doxorubicin | decreases expression | ISO | NDRG3 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of NDRG3 mRNA | CTD | PMID:29803840 | enzyme inhibitor | multiple interactions | ISO | NDRG3 (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of NDRG3 protein | CTD | PMID:23301498 | ethanol | multiple interactions | ISO | Ndrg3 (Mus musculus) | 6480464 | Ethanol affects the expression of and affects the splicing of NDRG3 mRNA | CTD | PMID:30319688 | formaldehyde | decreases expression | ISO | NDRG3 (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of NDRG3 mRNA | CTD | PMID:23649840 | FR900359 | affects phosphorylation | ISO | NDRG3 (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of NDRG3 protein | CTD | PMID:37730182 | fulvestrant | multiple interactions | ISO | NDRG3 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in decreased methylation of NDRG3 gene | CTD | PMID:31601247 | genistein | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Genistein] results in decreased methylation of NDRG3 gene | CTD | PMID:28505145 | glyphosate | affects methylation | EXP | | 6480464 | Glyphosate affects the methylation of NDRG3 gene | CTD | PMID:35440735 | glyphosate | increases methylation | EXP | | 6480464 | Glyphosate results in increased methylation of NDRG3 gene | CTD | PMID:31011160 | ivermectin | decreases expression | ISO | NDRG3 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of NDRG3 protein | CTD | PMID:32959892 | mercury dichloride | multiple interactions | ISO | NDRG3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NDRG3 mRNA | CTD | PMID:27188386 | methamphetamine | decreases expression | ISO | Ndrg3 (Mus musculus) | 6480464 | Methamphetamine results in decreased expression of NDRG3 mRNA | CTD | PMID:11756511 | methamphetamine | multiple interactions | ISO | Ndrg3 (Mus musculus) | 6480464 | (1R-(exo more ... | CTD | PMID:11756511 | methylmercury chloride | decreases expression | ISO | NDRG3 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of NDRG3 mRNA | CTD | PMID:28001369 | paracetamol | affects expression | ISO | Ndrg3 (Mus musculus) | 6480464 | Acetaminophen affects the expression of NDRG3 mRNA | CTD | PMID:17562736 | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of NDRG3 mRNA | CTD | PMID:33387578 | pirinixic acid | decreases expression | EXP | | 6480464 | pirinixic acid results in decreased expression of NDRG3 mRNA | CTD | PMID:19162173 | potassium dichromate | increases expression | ISO | NDRG3 (Homo sapiens) | 6480464 | Potassium Dichromate results in increased expression of NDRG3 protein | CTD | PMID:23718831 | rotenone | decreases expression | EXP | | 6480464 | Rotenone results in decreased expression of NDRG3 protein | CTD | PMID:35544339 | SB 431542 | multiple interactions | ISO | NDRG3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NDRG3 mRNA | CTD | PMID:27188386 | Soman | decreases expression | EXP | | 6480464 | Soman results in decreased expression of NDRG3 mRNA | CTD | PMID:19281266 | sulforaphane | decreases expression | ISO | NDRG3 (Homo sapiens) | 6480464 | sulforaphane results in decreased expression of NDRG3 mRNA | CTD | PMID:31838189 | sunitinib | decreases expression | ISO | NDRG3 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of NDRG3 mRNA | CTD | PMID:31533062 | temozolomide | decreases expression | ISO | NDRG3 (Homo sapiens) | 6480464 | Temozolomide results in decreased expression of NDRG3 mRNA | CTD | PMID:31758290 | tert-butyl hydroperoxide | decreases expression | ISO | NDRG3 (Homo sapiens) | 6480464 | tert-Butylhydroperoxide results in decreased expression of NDRG3 mRNA | CTD | PMID:15336504 | tetrachloromethane | affects expression | ISO | Ndrg3 (Mus musculus) | 6480464 | Carbon Tetrachloride affects the expression of NDRG3 mRNA | CTD | PMID:17484886 | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of NDRG3 mRNA | CTD | PMID:33387578 | triptonide | increases expression | ISO | Ndrg3 (Mus musculus) | 6480464 | triptonide results in increased expression of NDRG3 mRNA | CTD | PMID:33045310 | troglitazone | decreases expression | ISO | Ndrg3 (Mus musculus) | 6480464 | troglitazone results in decreased expression of NDRG3 mRNA | CTD | PMID:28973697 | valproic acid | affects expression | ISO | NDRG3 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of NDRG3 mRNA | CTD | PMID:25979313 | valproic acid | increases expression | ISO | NDRG3 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of NDRG3 mRNA | CTD | PMID:23179753 and PMID:27188386 | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of NDRG3 mRNA | CTD | PMID:23034163 | vorinostat | increases expression | ISO | NDRG3 (Homo sapiens) | 6480464 | vorinostat results in increased expression of NDRG3 mRNA | CTD | PMID:27188386 | |