RT1-CE13 (RT1 class I, locus CE13) - Rat Genome Database

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Gene: RT1-CE13 (RT1 class I, locus CE13) Rattus norvegicus
Analyze
No known orthologs.
Symbol: RT1-CE13
Name: RT1 class I, locus CE13
RGD ID: 1359196
Description: PARTICIPATES IN allograft rejection pathway; antigen processing and presentation pathway; autoimmune thyroiditis pathway; ASSOCIATED WITH acute retinal necrosis syndrome (ortholog); alopecia (ortholog); ankylosing spondylitis (ortholog)
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: RT1 class I, CE13
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2203,314,984 - 3,318,037 (-)NCBImRatBN7.2
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

References - curated
1. Abbas M, etal., Invest Ophthalmol Vis Sci. 2009 Apr;50(4):1734-8. doi: 10.1167/iovs.08-2053. Epub 2008 Sep 29.
2. Altman EM, etal., Ann Allergy. 1994 Apr;72(4):307-16.
3. Bel Hadj Ali I, etal., Ann Hum Biol. 2012 May;39(3):190-4. doi: 10.3109/03014460.2012.671849. Epub 2012 Apr 4.
4. Biswas J, etal., Int Ophthalmol. 1997-1998;21(5):277-81.
5. Blom DJ, etal., Invest Ophthalmol Vis Sci. 1997 Aug;38(9):1865-72.
6. Brown MA, etal., Ann Rheum Dis. 1996 Apr;55(4):268-70.
7. Cheung YK, etal., Epilepsia. 2013 Jul;54(7):1307-14. doi: 10.1111/epi.12217. Epub 2013 May 20.
8. Choukri F, etal., Tissue Antigens. 2003 Jan;61(1):92-6.
9. Dabil H, etal., Hum Immunol. 2003 Oct;64(10):960-4.
10. Ermakova NA Vestn Oftalmol. 2003 Jan-Feb;119(1):31-3.
11. Flor-de-Lima F, etal., Acta Paediatr. 2013 Aug 29. doi: 10.1111/apa.12410.
12. Gul A, etal., Rheumatology (Oxford). 2001 Jun;40(6):668-72.
13. Hammer RE, etal., Cell. 1990 Nov 30;63(5):1099-112.
14. Holland GN, etal., Am J Ophthalmol. 1989 Oct 15;108(4):370-4.
15. Huang SM, etal., Tissue Antigens. 2003 Feb;61(2):154-8.
16. Hughes EH, etal., Tissue Antigens. 2005 Sep;66(3):195-9.
17. Kang EH, etal., Hum Immunol. 2013 Oct;74(10):1363-7. doi: 10.1016/j.humimm.2013.06.036. Epub 2013 Jul 2.
18. Kaniwa N, etal., Pharmacogenomics. 2008 Nov;9(11):1617-22. doi: 10.2217/14622416.9.11.1617.
19. Kaya TI, etal., Clin Exp Dermatol. 2002 Sep;27(6):498-501.
20. Keles B, etal., Otolaryngol Head Neck Surg. 2008 Oct;139(4):580-5. doi: 10.1016/j.otohns.2008.07.002.
21. Kontopoulos A, etal., J Heart Valve Dis. 1996 Sep;5(5):543-7.
22. Kulahli I, etal., Hear Res. 2005 May;203(1-2):28-31.
23. Li Y, etal., Int J Med Sci. 2013;10(2):164-70. doi: 10.7150/ijms.5158. Epub 2013 Jan 3.
24. Liu WH, etal., Zhonghua Nei Ke Za Zhi. 1991 Jul;30(7):395-8, 454.
25. Matsuki K, etal., Arch Otolaryngol Head Neck Surg. 1989 Jan;115(1):46-7.
26. Murphy B, etal., Transplantation. 1997 Jul 15;64(1):14-9.
27. OMIM Disease Annotation Pipeline
28. Orchard TR, etal., Gastroenterology. 2000 Feb;118(2):274-8.
29. Orchard TR, etal., Gastroenterology. 2002 Sep;123(3):714-8.
30. Pathanapitoon K, etal., Br J Ophthalmol. 2006 Dec;90(12):1448-50. Epub 2006 Aug 9.
31. Pipeline to import KEGG annotations from KEGG into RGD
32. Price P, etal., J Clin Virol. 2001 Oct;22(3):279-87.
33. Priem HA, etal., Am J Ophthalmol. 1988 Feb 15;105(2):182-5.
34. Raache R, etal., J Fr Ophtalmol. 2013 Mar;36(3):247-54. doi: 10.1016/j.jfo.2012.01.008. Epub 2012 Sep 14.
35. Ratanachaiyavong S, etal., Hum Immunol. 1993 Feb;36(2):99-111.
36. Razumova IIu, etal., Vestn Oftalmol. 2013 Mar-Apr;129(2):35-40.
37. RGD automated data pipeline
38. RGD automated import pipeline for gene-chemical interactions
39. Tandon N, etal., Clin Endocrinol (Oxf). 1990 Jul;33(1):21-6.
40. Thurau SR, etal., Immunol Lett. 1997 Jun 1;57(1-3):193-201.
41. Villegas Becerril E, etal., Cell Mol Immunol. 2009 Aug;6(4):303-7. doi: 10.1038/cmi.2009.40.
42. Wildner G, etal., Ann N Y Acad Sci. 2004 Dec;1029:416-21.
43. Yanagisawa H, etal., Am J Pathol. 1995 Oct;147(4):955-64.
44. Yeo SW, etal., Acta Otolaryngol. 2002 Dec;122(8):851-6.
Additional References at PubMed
PMID:29531166  


Genomics


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724519Bp144Blood pressure QTL 1440.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2013624629Rat
1354642Despr15Despair related QTL 150.0027locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)20124159021Rat
1600382Edcs3Endometrial carcinoma susceptibility QTL33.50.003uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)20125159026Rat
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20129191651Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129191651Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20129191651Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129191651Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20129191651Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578807Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600972Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600972Rat
2305926Iddm37Insulin dependent diabetes mellitus QTL 376blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)20152784246527842Rat
2306850Pia40Pristane induced arthritis QTL 400.0001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)2015279595304575Rat
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20153065546530655Rat
1598816Memor12Memory QTL 122.4exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)20260683647606836Rat
61448Ciaa1CIA Autoantibody QTL 1300.001blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)2026463954597031Rat
61472Aia1Adjuvant induced arthritis QTL 1180.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)2026463954597031Rat
2317057Aia27Adjuvant induced arthritis QTL 272.83joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)20289259726381954Rat


Expression


Sequence


Reference Sequences
RefSeq Acc Id: NM_001008836   ⟹   NP_001008836
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2203,314,984 - 3,318,037 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001008836 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AVP72137 (Get FASTA)   NCBI Sequence Viewer  
  CAE84016 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001008836   ⟸   NM_001008836
- Peptide Label: precursor
- UniProtKB: Q6MG31 (UniProtKB/TrEMBL)
- Sequence:
Protein Domains
Ig-like


Additional Information

Database Acc Id Source(s)
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
  3.30.500.10 UniProtKB/TrEMBL
InterPro Ig-like UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig/MHC_CS UniProtKB/TrEMBL
  Ig_C1-set UniProtKB/TrEMBL
  MHC_I-like_Ag-recog UniProtKB/TrEMBL
  MHC_I-like_Ag-recog_sf UniProtKB/TrEMBL
  MHC_I/II-like_Ag-recog UniProtKB/TrEMBL
  MHC_I_a_a1/a2 UniProtKB/TrEMBL
  MHC_I_a_C UniProtKB/TrEMBL
KEGG Report rno:414790 UniProtKB/TrEMBL
NCBI Gene 414790 ENTREZGENE
Pfam C1-set UniProtKB/TrEMBL
  MHC_I UniProtKB/TrEMBL
  MHC_I_C UniProtKB/TrEMBL
PhenoGen RT1-CE13 PhenoGen
PRINTS MHCCLASSI UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/TrEMBL
  IG_MHC UniProtKB/TrEMBL
SMART IGc1 UniProtKB/TrEMBL
Superfamily-SCOP MHC_I/II-like_Ag-recog UniProtKB/TrEMBL
  SSF48726 UniProtKB/TrEMBL
UniProt A0A2P1NRY3_RAT UniProtKB/TrEMBL
  Q6MG31 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2009-09-15 RT1-CE13  RT1 class I, locus CE13  RT1-CE13  RT1 class I, CE13  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 RT1-CE13  RT1 class I, CE13      Symbol and Name updated 1559027 APPROVED
2005-07-29 RT1-CE13  RT1 class I, CE13      Symbol and Name status set to provisional 70820 PROVISIONAL