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Gene: CYRIB (CYFIP related Rac1 interactor B) Homo sapiens
Symbol: CYRIB
Name: CYFIP related Rac1 interactor B
Description: Predicted to have MHC class Ib protein binding, via antigen binding activity groove. Predicted to be involved in positive regulation of T cell mediated cytotoxicity; positive regulation of interferon-gamma production; and positive regulation of memory T cell activation. Localizes to the extracellular exosome; INTERACTS WITH (-)-epigallocatechin 3-gallate; 17beta-estradiol; 3-isobutyl-1-methyl-7H-xanthine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: BM-009; CYRI; CYRI-B; DKFZp686B04128; FAM49B; FAM49B/JPH1 fusion; family with sequence similarity 49 member B; family with sequence similarity 49, member B; hypothetical protein LOC51571; L1; MTSS1/FAM49B fusion
Mus musculus (house mouse) : Fam49b (family with sequence similarity 49, member B)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cyrib (CYFIP related Rac1 interactor B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cyrib (CYFIP related Rac1 interactor B)
Pan paniscus (bonobo/pygmy chimpanzee) : CYRIB (CYFIP related Rac1 interactor B)
Canis lupus familiaris (dog) : CYRIB (CYFIP related Rac1 interactor B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cyrib (CYFIP related Rac1 interactor B)
Sus scrofa (pig) : CYRIB (CYFIP related Rac1 interactor B)
Chlorocebus sabaeus (African green monkey) : CYRIB (CYFIP related Rac1 interactor B)
Heterocephalus glaber (naked mole-rat) : Cyrib (CYFIP related Rac1 interactor B)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl8129,839,593 - 130,017,129 (-)Ensembl
GRCh388129,839,593 - 130,017,129 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh378130,851,839 - 131,028,897 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368130,922,898 - 131,021,182 (-)NCBINCBI36hg18NCBI36
Build 348130,922,899 - 131,021,182NCBI
Celera8127,031,822 - 127,130,443 (-)NCBI
Cytogenetic Map8q24.21NCBI
HuRef8126,170,455 - 126,302,342 (-)NCBIHuRef
CHM1_18130,892,084 - 131,069,252 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences