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Gene: TMED1 (transmembrane p24 trafficking protein 1) Homo sapiens
Symbol: TMED1
Name: transmembrane p24 trafficking protein 1
Description: This gene belongs to the TMED (transmembrane emp24 domain-containing) protein family, which is involved in the vesicular trafficking of proteins. The protein encoded by this gene was identified by its interaction with interleukin 1 receptor-like 1 (IL1RL1) and may play a role in innate immunity. This protein lacks any similarity to other interleukin 1 ligands. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: IL1RL1-binding protein; Il1rl1l; IL1RL1LG; interleukin 1 receptor-like 1 ligand; interleukin-1 receptor-like 1 ligand; MGC1270; p24 family protein gamma-1; p24g1; p24gamma1; putative T1/ST2 receptor-binding protein; ST2L; T1/ST2 receptor binding protein; Tp24; transmembrane emp24 domain containing 1; transmembrane emp24 domain-containing protein 1; transmembrane emp24 protein transport domain containing 1
Mus musculus (house mouse) : Tmed1 (transmembrane p24 trafficking protein 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Tmed1 (transmembrane p24 trafficking protein 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tmed1 (transmembrane p24 trafficking protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : TMED1 (transmembrane p24 trafficking protein 1)
Canis lupus familiaris (dog) : TMED1 (transmembrane p24 trafficking protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tmed1 (transmembrane p24 trafficking protein 1)
Sus scrofa (pig) : TMED1 (transmembrane p24 trafficking protein 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381910,832,067 - 10,836,212 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371910,942,743 - 10,946,983 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361910,804,114 - 10,807,983 (-)NCBINCBI36hg18NCBI36
Build 341910,804,114 - 10,807,983NCBI
Celera1910,837,959 - 10,841,828 (-)NCBI
Cytogenetic Map19p13.2NCBI
HuRef1910,520,875 - 10,525,115 (-)NCBIHuRef
CHM1_11910,943,980 - 10,948,220 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on TMED1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1354453
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.