KRT35 (keratin 35) - Rat Genome Database

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Gene: KRT35 (keratin 35) Homo sapiens
Analyze
Symbol: KRT35
Name: keratin 35
RGD ID: 1354440
HGNC Page HGNC:6453
Description: Predicted to enable structural molecule activity. Predicted to be involved in epithelial cell differentiation and intermediate filament organization. Located in extracellular exosome.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: Ha-5; HA5; hair keratin, type I Ha5; hard keratin, type I, 5; hHa5; HHa5 hair keratin type I intermediate filament; K35; keratin 35, type I; keratin, hair, acidic, 5; keratin, type I cuticular Ha5; keratin-35; KRTHA5
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381741,476,710 - 41,481,151 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1741,476,710 - 41,481,151 (-)EnsemblGRCh38hg38GRCh38
GRCh371739,632,962 - 39,637,403 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361736,886,467 - 36,890,918 (-)NCBINCBI36Build 36hg18NCBI36
Build 341736,886,466 - 36,891,194NCBI
Celera1736,286,163 - 36,290,612 (-)NCBICelera
Cytogenetic Map17q21.2NCBI
HuRef1735,396,551 - 35,401,000 (-)NCBIHuRef
CHM1_11739,868,249 - 39,872,698 (-)NCBICHM1_1
T2T-CHM13v2.01742,332,251 - 42,336,690 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:7686952   PMID:8823373   PMID:9756910   PMID:10391933   PMID:15140206   PMID:16831889   PMID:17353931   PMID:18021261   PMID:19380743   PMID:19615732   PMID:21873635   PMID:23533145  
PMID:23580065   PMID:23686814   PMID:29845934   PMID:32296183   PMID:33838681   PMID:33961781   PMID:35864588   PMID:36244648  


Genomics

Comparative Map Data
KRT35
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381741,476,710 - 41,481,151 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1741,476,710 - 41,481,151 (-)EnsemblGRCh38hg38GRCh38
GRCh371739,632,962 - 39,637,403 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361736,886,467 - 36,890,918 (-)NCBINCBI36Build 36hg18NCBI36
Build 341736,886,466 - 36,891,194NCBI
Celera1736,286,163 - 36,290,612 (-)NCBICelera
Cytogenetic Map17q21.2NCBI
HuRef1735,396,551 - 35,401,000 (-)NCBIHuRef
CHM1_11739,868,249 - 39,872,698 (-)NCBICHM1_1
T2T-CHM13v2.01742,332,251 - 42,336,690 (-)NCBIT2T-CHM13v2.0
Krt35
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391199,983,018 - 99,987,050 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1199,983,019 - 99,987,067 (-)EnsemblGRCm39 Ensembl
GRCm3811100,092,192 - 100,096,224 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11100,092,193 - 100,096,241 (-)EnsemblGRCm38mm10GRCm38
MGSCv371199,953,506 - 99,957,538 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361199,908,288 - 99,912,315 (-)NCBIMGSCv36mm8
Celera11110,708,544 - 110,712,607 (-)NCBICelera
Cytogenetic Map11DNCBI
cM Map1163.4NCBI
Krt35
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81085,526,571 - 85,529,968 (-)NCBIGRCr8
mRatBN7.21085,026,171 - 85,029,568 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1085,026,171 - 85,029,568 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1090,044,470 - 90,047,872 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01089,542,524 - 89,545,921 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01084,934,476 - 84,937,873 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01088,006,179 - 88,009,576 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1088,006,179 - 88,009,576 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01087,798,389 - 87,801,786 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41089,031,289 - 89,034,686 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11089,045,658 - 89,049,056 (-)NCBI
Celera1083,745,827 - 83,749,224 (-)NCBICelera
Cytogenetic Map10q31NCBI
Krt35
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495545115,820,687 - 15,824,284 (-)NCBIChiLan1.0ChiLan1.0
KRT35
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21923,503,780 - 23,508,142 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11725,393,755 - 25,398,117 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01715,835,732 - 15,840,115 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11716,053,166 - 16,057,533 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1716,053,166 - 16,057,533 (+)Ensemblpanpan1.1panPan2
KRT35
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1921,286,925 - 21,292,699 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl921,287,584 - 21,292,339 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha920,748,716 - 20,754,485 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0922,007,866 - 22,013,640 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl922,007,925 - 22,013,645 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1920,793,869 - 20,799,638 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0921,059,892 - 21,065,658 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0921,163,698 - 21,169,463 (+)NCBIUU_Cfam_GSD_1.0
KRT35
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1221,166,484 - 21,171,915 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11221,166,366 - 21,171,894 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21221,447,219 - 21,452,620 (-)NCBISscrofa10.2Sscrofa10.2susScr3
KRT35
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11664,759,441 - 64,764,085 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1664,760,395 - 64,764,422 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607735,605,267 - 35,609,697 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Krt35
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247952,125,658 - 2,128,783 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247952,125,658 - 2,128,783 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in KRT35
28 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 17q21.33-24.2(chr17:36449220-68170214)x3 copy number gain See cases [RCV000050957] Chr17:36449220..68170214 [GRCh38]
Chr17:48563237..65936105 [GRCh37]
Chr17:45918236..63677950 [NCBI36]
Chr17:17q21.33-24.2		 pathogenic
GRCh38/hg38 17q23.2-25.3(chr17:36449220-83086677)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052483]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052483]|See cases [RCV000052483] Chr17:36449220..83086677 [GRCh38]
Chr17:58617905..81044553 [GRCh37]
Chr17:55972687..78637842 [NCBI36]
Chr17:17q23.2-25.3		 pathogenic
GRCh38/hg38 17q12-21.31(chr17:39199873-45629579)x3 copy number gain See cases [RCV000052479] Chr17:39199873..45629579 [GRCh38]
Chr17:37356126..43706945 [GRCh37]
Chr17:34609652..41062728 [NCBI36]
Chr17:17q12-21.31		 pathogenic
NM_002280.4(KRT35):c.1225C>T (p.Pro409Ser) single nucleotide variant Malignant melanoma [RCV000063217] Chr17:41477199 [GRCh38]
Chr17:39633451 [GRCh37]
Chr17:36886977 [NCBI36]
Chr17:17q21.2		 not provided
GRCh38/hg38 17q23.1-25.1(chr17:36449220-75053130)x3 copy number gain See cases [RCV000137437] Chr17:36449220..75053130 [GRCh38]
Chr17:57595736..73049225 [GRCh37]
Chr17:54950518..70560820 [NCBI36]
Chr17:17q23.1-25.1		 pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:526-81041938) copy number gain See cases [RCV000511439] Chr17:526..81041938 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
NM_002280.6(KRT35):c.68G>T (p.Gly23Val) single nucleotide variant Inborn genetic diseases [RCV003256218] Chr17:41481030 [GRCh38]
Chr17:39637282 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_002280.6(KRT35):c.611G>A (p.Arg204His) single nucleotide variant Inborn genetic diseases [RCV003239476] Chr17:41479447 [GRCh38]
Chr17:39635699 [GRCh37]
Chr17:17q21.2		 uncertain significance
GRCh37/hg19 17p13.3-q25.3(chr17:526-81041938)x3 copy number gain See cases [RCV000512441] Chr17:526..81041938 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:8547-81060040)x3 copy number gain not provided [RCV000739324] Chr17:8547..81060040 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:7214-81058310)x3 copy number gain not provided [RCV000739320] Chr17:7214..81058310 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:12344-81057996)x3 copy number gain not provided [RCV000739325] Chr17:12344..81057996 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
NM_002280.6(KRT35):c.1159C>T (p.Arg387Trp) single nucleotide variant Inborn genetic diseases [RCV002684916] Chr17:41477579 [GRCh38]
Chr17:39633831 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_002280.6(KRT35):c.320G>A (p.Arg107His) single nucleotide variant Inborn genetic diseases [RCV002754348] Chr17:41480778 [GRCh38]
Chr17:39637030 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_002280.6(KRT35):c.265G>T (p.Gly89Trp) single nucleotide variant Inborn genetic diseases [RCV003012820] Chr17:41480833 [GRCh38]
Chr17:39637085 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_002280.6(KRT35):c.1263G>C (p.Lys421Asn) single nucleotide variant Inborn genetic diseases [RCV003012899] Chr17:41477161 [GRCh38]
Chr17:39633413 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_002280.6(KRT35):c.995G>C (p.Ser332Thr) single nucleotide variant Inborn genetic diseases [RCV002818243] Chr17:41478365 [GRCh38]
Chr17:39634617 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_002280.6(KRT35):c.70G>A (p.Gly24Ser) single nucleotide variant Inborn genetic diseases [RCV002733557] Chr17:41481028 [GRCh38]
Chr17:39637280 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_002280.6(KRT35):c.1012G>C (p.Glu338Gln) single nucleotide variant Inborn genetic diseases [RCV002925213] Chr17:41477726 [GRCh38]
Chr17:39633978 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_002280.6(KRT35):c.1166G>A (p.Arg389Gln) single nucleotide variant Inborn genetic diseases [RCV002738279] Chr17:41477572 [GRCh38]
Chr17:39633824 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_002280.6(KRT35):c.1330C>T (p.Arg444Cys) single nucleotide variant Inborn genetic diseases [RCV002693492] Chr17:41477094 [GRCh38]
Chr17:39633346 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_002280.6(KRT35):c.394T>C (p.Trp132Arg) single nucleotide variant Inborn genetic diseases [RCV002823049] Chr17:41480704 [GRCh38]
Chr17:39636956 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_002280.6(KRT35):c.1126C>A (p.Gln376Lys) single nucleotide variant Inborn genetic diseases [RCV002891438] Chr17:41477612 [GRCh38]
Chr17:39633864 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_002280.6(KRT35):c.905G>C (p.Ser302Thr) single nucleotide variant Inborn genetic diseases [RCV002892271] Chr17:41478455 [GRCh38]
Chr17:39634707 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_002280.6(KRT35):c.964G>A (p.Ala322Thr) single nucleotide variant Inborn genetic diseases [RCV002712318] Chr17:41478396 [GRCh38]
Chr17:39634648 [GRCh37]
Chr17:17q21.2		 likely benign
NM_002280.6(KRT35):c.1148T>A (p.Leu383Gln) single nucleotide variant Inborn genetic diseases [RCV002879135] Chr17:41477590 [GRCh38]
Chr17:39633842 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_002280.6(KRT35):c.727C>T (p.Arg243Cys) single nucleotide variant Inborn genetic diseases [RCV002920623] Chr17:41478980 [GRCh38]
Chr17:39635232 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_002280.6(KRT35):c.1297G>A (p.Gly433Ser) single nucleotide variant Inborn genetic diseases [RCV002719753] Chr17:41477127 [GRCh38]
Chr17:39633379 [GRCh37]
Chr17:17q21.2		 likely benign
NM_002280.6(KRT35):c.68G>A (p.Gly23Glu) single nucleotide variant Inborn genetic diseases [RCV002723636] Chr17:41481030 [GRCh38]
Chr17:39637282 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_002280.6(KRT35):c.895G>C (p.Val299Leu) single nucleotide variant Inborn genetic diseases [RCV003374686] Chr17:41478465 [GRCh38]
Chr17:39634717 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_002280.6(KRT35):c.32C>G (p.Ser11Cys) single nucleotide variant Inborn genetic diseases [RCV003374593] Chr17:41481066 [GRCh38]
Chr17:39637318 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_002280.6(KRT35):c.130C>T (p.Pro44Ser) single nucleotide variant Inborn genetic diseases [RCV003368851] Chr17:41480968 [GRCh38]
Chr17:39637220 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_002280.6(KRT35):c.667T>C (p.Ser223Pro) single nucleotide variant Inborn genetic diseases [RCV003369282] Chr17:41479391 [GRCh38]
Chr17:39635643 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_002280.6(KRT35):c.642G>A (p.Lys214=) single nucleotide variant not provided [RCV003419737] Chr17:41479416 [GRCh38]
Chr17:39635668 [GRCh37]
Chr17:17q21.2		 likely benign
NM_002280.6(KRT35):c.366C>T (p.Asn122=) single nucleotide variant not provided [RCV003419738] Chr17:41480732 [GRCh38]
Chr17:39636984 [GRCh37]
Chr17:17q21.2		 likely benign
NM_002280.6(KRT35):c.1188G>A (p.Thr396=) single nucleotide variant not provided [RCV003413228] Chr17:41477550 [GRCh38]
Chr17:39633802 [GRCh37]
Chr17:17q21.2		 likely benign
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:519
Count of miRNA genes:308
Interacting mature miRNAs:336
Transcripts:ENST00000246639, ENST00000393989
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
STS-X90762  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371739,632,942 - 39,633,179UniSTSGRCh37
Build 361736,886,468 - 36,886,705RGDNCBI36
Celera1736,286,164 - 36,286,401RGD
Cytogenetic Map17q21.2UniSTS
HuRef1735,396,552 - 35,396,789UniSTS
GeneMap99-GB4 RH Map17304.61UniSTS
NCBI RH Map17352.4UniSTS
KRTHA5__6360  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371739,632,754 - 39,633,429UniSTSGRCh37
Build 361736,886,280 - 36,886,955RGDNCBI36
Celera1736,285,976 - 36,286,651RGD
HuRef1735,396,364 - 35,397,039UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High 17 1
Medium 259 2 5 126
Low 14 9 9 12 27 1 249 6 49 4 9 14 10 9 165 1
Below cutoff 833 1074 565 165 553 74 2174 785 1463 103 763 478 94 542 1502

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000246639   ⟹   ENSP00000246639
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1741,476,710 - 41,481,151 (-)Ensembl
RefSeq Acc Id: ENST00000393989   ⟹   ENSP00000377558
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1741,476,690 - 41,481,140 (-)Ensembl
RefSeq Acc Id: NM_002280   ⟹   NP_002271
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381741,476,710 - 41,481,151 (-)NCBI
GRCh371739,632,941 - 39,637,392 (-)RGD
Build 361736,886,467 - 36,890,918 (-)NCBI Archive
Celera1736,286,163 - 36,290,612 (-)RGD
HuRef1735,396,551 - 35,401,000 (-)ENTREZGENE
CHM1_11739,868,249 - 39,872,698 (-)NCBI
T2T-CHM13v2.01742,332,251 - 42,336,690 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_002271 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein CAA62285 (Get FASTA)   NCBI Sequence Viewer  
  CAA62286 (Get FASTA)   NCBI Sequence Viewer  
  CAA76387 (Get FASTA)   NCBI Sequence Viewer  
  EAW60736 (Get FASTA)   NCBI Sequence Viewer  
  EAW60737 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000246639
  ENSP00000246639.3
GenBank Protein Q92764 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_002271   ⟸   NM_002280
- UniProtKB: O76012 (UniProtKB/Swiss-Prot),   Q92651 (UniProtKB/Swiss-Prot),   Q92764 (UniProtKB/Swiss-Prot),   C4AM86 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000246639   ⟸   ENST00000246639
RefSeq Acc Id: ENSP00000377558   ⟸   ENST00000393989
Protein Domains
IF rod

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q92764-F1-model_v2 AlphaFold Q92764 1-455 view protein structure

Promoters
RGD ID:7234981
Promoter ID:EPDNEW_H23237
Type:single initiation site
Name:KRT35_1
Description:keratin 35
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381741,481,068 - 41,481,128EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:6453 AgrOrtholog
COSMIC KRT35 COSMIC
Ensembl Genes ENSG00000197079 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000246639 ENTREZGENE, UniProtKB/TrEMBL
  ENST00000246639.7 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.5.170 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Single helix bin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Vasodilator-stimulated phosphoprotein UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000197079 GTEx
HGNC ID HGNC:6453 ENTREZGENE
Human Proteome Map KRT35 Human Proteome Map
InterPro IF_conserved UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IF_rod_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Keratin_I UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:3886 UniProtKB/Swiss-Prot
NCBI Gene 3886 ENTREZGENE
OMIM 602764 OMIM
PANTHER KERATIN, TYPE I CUTICULAR HA5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR23239 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Filament UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA30242 PharmGKB
PRINTS TYPE1KERATIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE IF_ROD_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IF_ROD_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART Filament UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Intermediate filament protein, coiled coil region UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prefoldin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt C4AM86 ENTREZGENE, UniProtKB/TrEMBL
  KRT35_HUMAN UniProtKB/Swiss-Prot
  O76012 ENTREZGENE
  Q92651 ENTREZGENE
  Q92764 ENTREZGENE
UniProt Secondary O76012 UniProtKB/Swiss-Prot
  Q92651 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-14 KRT35  keratin 35  KRT35  keratin 35, type I  Symbol and/or name change 5135510 APPROVED
2015-01-27 KRT35  keratin 35, type I  KRT35  keratin 35  Symbol and/or name change 5135510 APPROVED