OR4C11 (olfactory receptor family 4 subfamily C member 11)

Gene: OR4C11 (olfactory receptor family 4 subfamily C member 11) Homo sapiens

Analyze

Symbol:

OR4C11

Name:

olfactory receptor family 4 subfamily C member 11

RGD ID:

1354381

HGNC Page

HGNC:15167

Description:

Predicted to enable olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and detection of chemical stimulus involved in sensory perception of smell. Predicted to be located in plasma membrane.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

olfactory receptor 4C11; olfactory receptor OR11-136; olfactory receptor, family 4, subfamily C, member 11 pseudogene; OR11-136; OR4C11P

RGD Orthologs

Alliance Genes

More Info

more info ...

Allele / Splice:

See ClinVar data

Latest Assembly:

GRCh38 - Human Genome Assembly GRCh38

Position:

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	55,602,360 - 55,607,645 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	55,602,360 - 55,607,645 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	55,369,836 - 55,375,121 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	55,127,493 - 55,128,425 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	11	55,127,492 - 55,128,425	NCBI
Celera	11	52,712,746 - 52,713,678 (-)	NCBI		Celera
Cytogenetic Map	11	q11	NCBI
HuRef	11	51,700,199 - 51,701,243 (-)	NCBI		HuRef
CHM1_1	11	55,236,089 - 55,237,133 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	11	55,540,617 - 55,545,902 (-)	NCBI		T2T-CHM13v2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (IAGP)

intellectual disability (IAGP)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

6-propyl-2-thiouracil (ISO)

acrylamide (ISO)

bisphenol A (ISO)

monosodium L-glutamate (ISO)

sodium arsenite (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

detection of chemical stimulus involved in sensory perception of smell (IEA)

G protein-coupled receptor signaling pathway (IEA)

sensory perception of smell (IEA)

Cellular Component

membrane (IEA)

plasma membrane (IBA,IEA)

Molecular Function

G protein-coupled receptor activity (IEA)

olfactory receptor activity (IBA,IEA)

Phenotype Annotations Click to see Annotation Detail View

Human Phenotype

Intellectual disability (IAGP)

References

References - curated

#	Reference Title	Reference Citation
1.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:14983052	PMID:21873635

Genomics

Comparative Map Data

OR4C11
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	55,602,360 - 55,607,645 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	55,602,360 - 55,607,645 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	55,369,836 - 55,375,121 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	55,127,493 - 55,128,425 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	11	55,127,492 - 55,128,425	NCBI
Celera	11	52,712,746 - 52,713,678 (-)	NCBI		Celera
Cytogenetic Map	11	q11	NCBI
HuRef	11	51,700,199 - 51,701,243 (-)	NCBI		HuRef
CHM1_1	11	55,236,089 - 55,237,133 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	11	55,540,617 - 55,545,902 (-)	NCBI		T2T-CHM13v2.0

Or4c11
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	88,694,951 - 88,695,874 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	88,693,575 - 88,698,097 (+)	Ensembl		GRCm39 Ensembl
GRCm38	2	88,864,607 - 88,865,530 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	88,863,231 - 88,867,753 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	88,704,764 - 88,705,687 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	88,665,446 - 88,666,369 (+)	NCBI		MGSCv36	mm8
Celera	2	90,444,682 - 90,445,315 (+)	NCBI		Celera
Cytogenetic Map	2	E1	NCBI
cM Map	2	50.03	NCBI

Or4c11
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	95,055,005 - 95,055,928 (+)	NCBI		GRCr8
mRatBN7.2	3	74,598,809 - 74,599,732 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	74,579,912 - 74,603,428 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	77,978,246 - 77,979,169 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	86,576,791 - 86,577,714 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	84,393,453 - 84,394,376 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	77,431,389 - 77,432,312 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	77,431,389 - 77,432,312 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	84,225,718 - 84,226,641 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	72,916,576 - 72,917,499 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	72,812,947 - 72,813,871 (+)	NCBI
Celera	3	73,862,139 - 73,863,062 (+)	NCBI		Celera
Cytogenetic Map	3	q24	NCBI

OR4C11J
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	18	40,520,711 - 40,521,643 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	18	40,520,711 - 40,521,643 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
ROS_Cfam_1.0	18	41,224,778 - 41,225,710 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	18	41,224,778 - 41,225,710 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UNSW_CanFamBas_1.0	18	40,240,191 - 40,240,704 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	18	40,974,765 - 40,975,697 (-)	NCBI		UU_Cfam_GSD_1.0

LOC100516851
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	2	14,176,715 - 14,177,647 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	14,943,686 - 14,944,618 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

LOC103235777
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	16,844,670 - 16,847,734 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	16,845,776 - 16,846,708 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	114,152,468 - 114,153,499 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Variants

Variants in OR4C11
23 total Variants

Clinical Variants

Name	Type	Condition(s)	Position(s)	Clinical significance
Single allele	deletion	Intellectual disability [RCV001293382]	Chr11:118359328..118372573 [GRCh37] Chr11:11p15.3-q23.3	pathogenic
GRCh38/hg38 11q11-12.1(chr11:55319519-56212930)x3	copy number gain	See cases [RCV000050318]	Chr11:55319519..56212930 [GRCh38] Chr11:55086995..55980406 [GRCh37] Chr11:54843571..55736982 [NCBI36] Chr11:11q11-12.1	benign
GRCh38/hg38 11q11-12.1(chr11:55445689-57114783)x1	copy number loss	See cases [RCV000050913]	Chr11:55445689..57114783 [GRCh38] Chr11:55213165..56882257 [GRCh37] Chr11:54969741..56638833 [NCBI36] Chr11:11q11-12.1	benign
GRCh38/hg38 11q11-12.1(chr11:55265785-56230226)x3	copy number gain	See cases [RCV000134403]	Chr11:55265785..56230226 [GRCh38] Chr11:55033261..55997702 [GRCh37] Chr11:54789837..55754278 [NCBI36] Chr11:11q11-12.1	benign
GRCh38/hg38 11q11(chr11:55600678-55792684)x1	copy number loss	See cases [RCV000135469]	Chr11:55600678..55792684 [GRCh38] Chr11:55368154..55560160 [GRCh37] Chr11:55124730..55316736 [NCBI36] Chr11:11q11	benign
GRCh38/hg38 11q11(chr11:55600886-55683282)x0	copy number loss	See cases [RCV000136263]	Chr11:55600886..55683282 [GRCh38] Chr11:55368362..55450758 [GRCh37] Chr11:55124938..55207334 [NCBI36] Chr11:11q11	benign
GRCh38/hg38 11q11(chr11:55600886-55683282)x3	copy number gain	See cases [RCV000136265]	Chr11:55600886..55683282 [GRCh38] Chr11:55368362..55450758 [GRCh37] Chr11:55124938..55207334 [NCBI36] Chr11:11q11	benign
GRCh38/hg38 11q11(chr11:55600886-55683282)x1	copy number loss	See cases [RCV000136266]	Chr11:55600886..55683282 [GRCh38] Chr11:55368362..55450758 [GRCh37] Chr11:55124938..55207334 [NCBI36] Chr11:11q11	benign
GRCh38/hg38 11q11(chr11:55600886-55671230)x3	copy number gain	See cases [RCV000136402]	Chr11:55600886..55671230 [GRCh38] Chr11:55368362..55438706 [GRCh37] Chr11:55124938..55195282 [NCBI36] Chr11:11q11	benign
GRCh38/hg38 11q11-12.1(chr11:55316591-55855055)x3	copy number gain	See cases [RCV000138732]	Chr11:55316591..55855055 [GRCh38] Chr11:55084067..55622531 [GRCh37] Chr11:54840643..55379107 [NCBI36] Chr11:11q11-12.1	likely benign
GRCh38/hg38 11q11(chr11:55570224-55683419)x3	copy number gain	See cases [RCV000138771]	Chr11:55570224..55683419 [GRCh38] Chr11:55337700..55450895 [GRCh37] Chr11:55094276..55207471 [NCBI36] Chr11:11q11	likely benign
GRCh38/hg38 11q11(chr11:55522385-55728510)x3	copy number gain	See cases [RCV000138984]	Chr11:55522385..55728510 [GRCh38] Chr11:55289861..55495986 [GRCh37] Chr11:55046437..55252562 [NCBI36] Chr11:11q11	likely benign
GRCh38/hg38 11q11-12.1(chr11:55316535-57539457)x3	copy number gain	See cases [RCV000141200]	Chr11:55316535..57539457 [GRCh38] Chr11:55084011..57306930 [GRCh37] Chr11:54840587..57063506 [NCBI36] Chr11:11q11-12.1	uncertain significance
GRCh38/hg38 11q11-12.1(chr11:55319519-58998777)x3	copy number gain	See cases [RCV000142757]	Chr11:55319519..58998777 [GRCh38] Chr11:55086995..58766250 [GRCh37] Chr11:54843571..58522826 [NCBI36] Chr11:11q11-12.1	pathogenic
GRCh38/hg38 11q11-12.1(chr11:55319519-56212930)x3	copy number gain	See cases [RCV000148269]	Chr11:55319519..56212930 [GRCh38] Chr11:55086995..55980406 [GRCh37] Chr11:54843571..55736982 [NCBI36] Chr11:11q11-12.1	benign
GRCh38/hg38 11q11(chr11:55354862-55683570)x0	copy number loss	Premature ovarian failure [RCV000225347]	Chr11:55354862..55683570 [GRCh38] Chr11:55122337..55451045 [GRCh37] Chr11:11q11	benign
GRCh37/hg19 11q11-12.1(chr11:55033164-55980347)x3	copy number gain	See cases [RCV000448938]	Chr11:55033164..55980347 [GRCh37] Chr11:11q11-12.1	benign
GRCh37/hg19 11q11-12.1(chr11:55029738-55980347)x3	copy number gain	See cases [RCV000448359]	Chr11:55029738..55980347 [GRCh37] Chr11:11q11-12.1	benign
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470)	copy number gain	See cases [RCV000511729]	Chr11:230616..134938470 [GRCh37] Chr11:11p15.5-q25	pathogenic
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470)x3	copy number gain	See cases [RCV000510881]	Chr11:230616..134938470 [GRCh37] Chr11:11p15.5-q25	pathogenic
NM_001004700.3(OR4C11):c.169A>G (p.Met57Val)	single nucleotide variant	Inborn genetic diseases [RCV003274441]	Chr11:55604205 [GRCh38] Chr11:55371681 [GRCh37] Chr11:11q11	uncertain significance
GRCh37/hg19 11p11.12-q12.1(chr11:51183548-56977098)x3	copy number gain	See cases [RCV000512524]	Chr11:51183548..56977098 [GRCh37] Chr11:11p11.12-q12.1	uncertain significance
GRCh37/hg19 11p11.12-q12.1(chr11:49313405-59008426)x3	copy number gain	not provided [RCV000683370]	Chr11:49313405..59008426 [GRCh37] Chr11:11p11.12-q12.1	uncertain significance
GRCh37/hg19 11p15.5-q25(chr11:198510-134934063)x3	copy number gain	not provided [RCV000737348]	Chr11:198510..134934063 [GRCh37] Chr11:11p15.5-q25	pathogenic
GRCh37/hg19 11q11-12.1(chr11:54697347-56021284)x3	copy number gain	not provided [RCV000737528]	Chr11:54697347..56021284 [GRCh37] Chr11:11q11-12.1	benign
GRCh37/hg19 11q11-12.1(chr11:54794237-56003589)x3	copy number gain	not provided [RCV000737530]	Chr11:54794237..56003589 [GRCh37] Chr11:11q11-12.1	benign
GRCh37/hg19 11p15.5-q25(chr11:70864-134938470)x3	copy number gain	not provided [RCV000749874]	Chr11:70864..134938470 [GRCh37] Chr11:11p15.5-q25	pathogenic
Single allele	duplication	not provided [RCV000844966]	Chr11:55033164..57518726 [GRCh37] Chr11:11q11-12.1	not provided
GRCh37/hg19 11p11.12-q12.1(chr11:51164494-56879839)x3	copy number gain	not provided [RCV001827812]	Chr11:51164494..56879839 [GRCh37] Chr11:11p11.12-q12.1	uncertain significance
GRCh37/hg19 11p13-q25(chr11:32799481-134938470)x3	copy number gain	MISSED ABORTION [RCV002282973]	Chr11:32799481..134938470 [GRCh37] Chr11:11p13-q25	pathogenic
GRCh37/hg19 11p11.2-q12.2(chr11:51581311-54891247)x3	copy number gain	See cases [RCV002286338]	Chr11:51581311..54891247 [GRCh37] Chr11:11p11.2-q12.2	pathogenic
NM_001004700.3(OR4C11):c.506C>A (p.Pro169His)	single nucleotide variant	Inborn genetic diseases [RCV002752979]	Chr11:55603868 [GRCh38] Chr11:55371344 [GRCh37] Chr11:11q11	uncertain significance
NM_001004700.3(OR4C11):c.433C>T (p.Leu145Phe)	single nucleotide variant	Inborn genetic diseases [RCV002777954]	Chr11:55603941 [GRCh38] Chr11:55371417 [GRCh37] Chr11:11q11	uncertain significance
NM_001004700.3(OR4C11):c.209G>A (p.Cys70Tyr)	single nucleotide variant	Inborn genetic diseases [RCV002734241]	Chr11:55604165 [GRCh38] Chr11:55371641 [GRCh37] Chr11:11q11	uncertain significance
NM_001004700.3(OR4C11):c.128T>A (p.Ile43Asn)	single nucleotide variant	Inborn genetic diseases [RCV002793794]	Chr11:55604246 [GRCh38] Chr11:55371722 [GRCh37] Chr11:11q11	uncertain significance
NM_001004700.3(OR4C11):c.928G>A (p.Gly310Arg)	single nucleotide variant	Inborn genetic diseases [RCV002757766]	Chr11:55603446 [GRCh38] Chr11:55370922 [GRCh37] Chr11:11q11	uncertain significance
NM_001004700.3(OR4C11):c.542C>A (p.Pro181His)	single nucleotide variant	Inborn genetic diseases [RCV002798667]	Chr11:55603832 [GRCh38] Chr11:55371308 [GRCh37] Chr11:11q11	uncertain significance
NM_001004700.3(OR4C11):c.523T>C (p.Tyr175His)	single nucleotide variant	Inborn genetic diseases [RCV002758521]	Chr11:55603851 [GRCh38] Chr11:55371327 [GRCh37] Chr11:11q11	uncertain significance
NM_001004700.3(OR4C11):c.776C>A (p.Pro259His)	single nucleotide variant	Inborn genetic diseases [RCV002926524]	Chr11:55603598 [GRCh38] Chr11:55371074 [GRCh37] Chr11:11q11	uncertain significance
NM_001004700.3(OR4C11):c.368C>G (p.Ala123Gly)	single nucleotide variant	Inborn genetic diseases [RCV002915157]	Chr11:55604006 [GRCh38] Chr11:55371482 [GRCh37] Chr11:11q11	uncertain significance
NM_001004700.3(OR4C11):c.779C>T (p.Pro260Leu)	single nucleotide variant	Inborn genetic diseases [RCV002641539]	Chr11:55603595 [GRCh38] Chr11:55371071 [GRCh37] Chr11:11q11	uncertain significance
NM_001004700.3(OR4C11):c.801G>T (p.Lys267Asn)	single nucleotide variant	Inborn genetic diseases [RCV002896887]	Chr11:55603573 [GRCh38] Chr11:55371049 [GRCh37] Chr11:11q11	uncertain significance
NM_001004700.3(OR4C11):c.402G>A (p.Met134Ile)	single nucleotide variant	Inborn genetic diseases [RCV002769094]	Chr11:55603972 [GRCh38] Chr11:55371448 [GRCh37] Chr11:11q11	uncertain significance
NM_001004700.3(OR4C11):c.27A>T (p.Glu9Asp)	single nucleotide variant	Inborn genetic diseases [RCV002877691]	Chr11:55604347 [GRCh38] Chr11:55371823 [GRCh37] Chr11:11q11	uncertain significance
NM_001004700.3(OR4C11):c.830C>T (p.Thr277Ile)	single nucleotide variant	Inborn genetic diseases [RCV003197406]	Chr11:55603544 [GRCh38] Chr11:55371020 [GRCh37] Chr11:11q11	uncertain significance
NM_001004700.3(OR4C11):c.830C>A (p.Thr277Lys)	single nucleotide variant	Inborn genetic diseases [RCV003219547]	Chr11:55603544 [GRCh38] Chr11:55371020 [GRCh37] Chr11:11q11	uncertain significance
NM_001004700.3(OR4C11):c.568A>G (p.Thr190Ala)	single nucleotide variant	Inborn genetic diseases [RCV003184698]	Chr11:55603806 [GRCh38] Chr11:55371282 [GRCh37] Chr11:11q11	uncertain significance
NM_001004700.3(OR4C11):c.177C>G (p.Phe59Leu)	single nucleotide variant	Inborn genetic diseases [RCV003207902]	Chr11:55604197 [GRCh38] Chr11:55371673 [GRCh37] Chr11:11q11	uncertain significance
NM_001004700.3(OR4C11):c.247G>T (p.Ala83Ser)	single nucleotide variant	Inborn genetic diseases [RCV003204038]	Chr11:55604127 [GRCh38] Chr11:55371603 [GRCh37] Chr11:11q11	uncertain significance
NM_001004700.3(OR4C11):c.151C>T (p.Arg51Trp)	single nucleotide variant	Inborn genetic diseases [RCV003207901]	Chr11:55604223 [GRCh38] Chr11:55371699 [GRCh37] Chr11:11q11	uncertain significance
NM_001004700.3(OR4C11):c.639A>G (p.Ile213Met)	single nucleotide variant	Inborn genetic diseases [RCV003373540]	Chr11:55603735 [GRCh38] Chr11:55371211 [GRCh37] Chr11:11q11	uncertain significance
NM_001004700.3(OR4C11):c.170T>A (p.Met57Lys)	single nucleotide variant	Inborn genetic diseases [RCV003356275]	Chr11:55604204 [GRCh38] Chr11:55371680 [GRCh37] Chr11:11q11	uncertain significance
GRCh37/hg19 11p11.12-q13.1(chr11:50398499-63924462)x3	copy number gain	not specified [RCV003986918]	Chr11:50398499..63924462 [GRCh37] Chr11:11p11.12-q13.1	likely pathogenic

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	141
Count of miRNA genes:	139
Interacting mature miRNAs:	141
Transcripts:	ENST00000302231
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region

OR4C11__7151

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	11	55,370,814 - 55,371,391	UniSTS	GRCh37
Build 36	11	55,127,390 - 55,127,967	RGD	NCBI36
Celera	11	52,712,643 - 52,713,220	RGD
HuRef	11	51,700,183 - 51,700,760	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	adipose tissue	appendage
High
Medium
Low
Below cutoff	28	21	10	7	33	3	28	26	31	4	160	4	4	7	18

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001004700	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB065774	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AP006437	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC140727	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BK004503	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH471076	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CP068267	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KP290311	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENST00000302231 ⟹ ENSP00000306651

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	11	55,603,354 - 55,604,398 (-)	Ensembl

RefSeq Acc Id:

ENST00000641580 ⟹ ENSP00000492971

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	11	55,602,360 - 55,607,645 (-)	Ensembl

RefSeq Acc Id:

NM_001004700 ⟹ NP_001004700

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	11	55,602,360 - 55,607,645 (-)	NCBI
GRCh37	11	55,370,830 - 55,371,874 (-)	ENTREZGENE
Build 36	11	55,127,493 - 55,128,425 (-)	NCBI Archive
Celera	11	52,712,746 - 52,713,678 (-)	RGD
HuRef	11	51,700,199 - 51,701,243 (-)	ENTREZGENE
CHM1_1	11	55,236,089 - 55,237,133 (-)	NCBI
T2T-CHM13v2.0	11	55,540,617 - 55,545,902 (-)	NCBI

Sequence:

show sequence

ACCAAAGAGAGCCTCGTATCAGAATAGTTATATATTAATTTATAAGCACTTTTAAAATTCTCAT
TTGAATAAGTAGCCTCCAAATTATATTGGGAAGAAAAGAGGGCAATTGAACATCCTAATATAGC
ATACTCTCTTATCAAAGCTGGTAAGGTCTGTATAGGAGAATAACTTAGTCGTATCTAACATTCA
GAGAAGGTGGATCTGATCAATACAACAGCCAGGAACTAACATATACAAGACACTGGTGGGAGGT
GGGGAAATTCAAGGACTTTTCTAGAAGTGCTTTACAATCTAAAGTGAAAAGATGGAAATAAAAA
TCATGCACAGAATTTCTTGATGGAAATGGGCACTACCAGAGCCCTGAGTTTCAACACTACTGCT
ATATCTGACTTACTCAAATTTGTGAGGCTTAATGTAGCCCTAAGAATACCACTAGAATTCCTGT
CTACAACAAGACAGTTGTGATGGCTCAGGGATATGCCATCACAAGGTGAATAACAACCCATCTC
CCAAGCCTCAGTGTCTACTTGTCTCTTAAGAAAACTTTATGAAGAACCCAGAAAAATAAGGAAA
GATGGACGAATTTAACTTTGGACAACACAGTATAACAAAGCAGTACAAAGTTGAATAATAAAGG
ATGAATTTGGAACTGAAAATAATTAGAAAATTTTCAGAGATTAACTAGTTCTAATCTGTGGTTT
CTTCACATCAACTGAAACAATGCAGCAAAATAACAGTGTGCCTGAATTCATACTGTTAGGATTA
ACACAGGATCCCTTGAGGCAGAAAATAGTGTTTGTAATCTTCTTAATTTTCTATATGGGAACTG
TGGTGGGGAATATGCTCATTATTGTGACCATCAAGTCCAGCCGGACACTAGGAAGCCCCATGTA
CTTCTTTCTATTTTATTTGTCCTTTGCAGATTCTTGCTTTTCAACTTCCACAGCCCCTAGATTA
ATTGTGGATGCTCTCTCTGAAAAGAAAATTATAACCTACAATGAGTGCATGACACAAGTCTTTG
CACTACATTTATTTGGCTGCATGGAGATCTTTGTCCTCATTCTCATGGCTGTTGATCGCTATGT
GGCCATCTGTAAGCCCTTGCGTTACCCAACCATCATGAGCCAGCAGGTCTGCATCATCCTGATT
GTTCTTGCCTGGATAGGGTCTTTAATACACTCTACAGCTCAGATTATCCTGGCCTTAAGATTGC
CTTTCTGTGGACCCTATTTGATTGATCATTATTGCTGTGATTTGCAGCCCTTGTTGAAACTTGC
CTGCATGGACACTTACATGATCAACCTGCTGTTGGTGTCTAACAGTGGGGCAATTTGCTCAAGT
AGTTTCATGATTTTGATAATTTCATATATTGTCATCTTGCATTCACTGAGAAACCACAGTGCCA
AAGGGAAGAAAAAGGCTCTCTCCGCTTGCACGTCTCACATAATTGTAGTCATCTTATTCTTTGG
CCCATGTATATTCATATATACACGCCCCCCGACCACTTTCCCCATGGACAAGATGGTGGCAGTA
TTTTATACTATTGGAACACCCTTTCTCAATCCACTCATCTACACACTGAGGAATGCAGAAGTGA
AAAATGCCATGAGAAAGTTATGGCATGGCAAAATTATTTCAGAAAACAAAGGATAAATTGAGGG
CCTGACCTGATTACTTTTTCAGTCAAATCATGATTTAACAGAGTAAGTATAGACAGCAAATAGG
AAAGTACCTGAATGCTGTGGGAATAATATATCATCGTATCTAAGTTTGTGGGTTCCTATGTTTT
CTAGTTAACAGGAGTTGTGACTACCAAGACATTGTCTTTTGTGCCAGAACTAGGTAGAATATAG
ATTAATTCAGGTGATTACCTACCAGTAGTCTTTTCTTTTCAGATTATCTTCCTTTCCAGCCATG
CATTTTCTAAAGTGTAAGCCTGACTATCTCTATGCACTCTAATCTAATGCATCTGATTTTCTTA
CTTCTTTCCTGTGCTTTTGACCACAGACTGATAAACTCCCTGAAATCTTCAATTTGGCTCTTCC
TTTTCCTAAGAGCCCAATTCTGCCATTGCTGGTTGTGAACTACACATCACAACTCTGTCTACAC
TCTGGTTTAATAAAAAGAAAGACATTTATACAATCACAAGTGTTCAAATTTGTGAGCACCAACA
AAGAAATGTCAAATTCCTTCCCTAATGCATTTGCAATAAGGTATCAAGCTTCCTCCTGAACACT
TCTAGGGAAAAGGAACTAACTCAGTATATCAAGATGCCCATTTACATTTTATCACTACTTTGTA
TTTAAAAAGTTCTGTATTTTTGAGTCAGAGGCTAATATACTGGAGATACAACATATTTCCTGAG
CCTGAAGTGCAGAAGGGTAGAACATGGTTGAAACCAAAAATGGTATGATCTATTGTGTTTAAAG
TTGGGTGATGTCAATGAAATAAATAAAATTATCACAGGAATTCAGAAAACACTCAGGACACTTG
TCTCTAGTGGGTTCTCCCTAAACAGGGAACCCACTACTGCTATAGGAAGTTACATCTCTATTTA
TTCTGTCCTAATAATTGGGGCTGCATAGAATCACAAGTTAGAATTGGCAATGGAATTTTCATGC
CCAGAGTGAGGACAGCAGATAAAAAGCGGCACTTTAGATATTCATATTATGGACTTTTAATATT
CATCTGTTTCAGTGTAATAAGTGTACCACATCTTTAATAACTGTTGACA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001004700	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI40728	(Get FASTA)	NCBI Sequence Viewer
	ALI87489	(Get FASTA)	NCBI Sequence Viewer
	BAC05994	(Get FASTA)	NCBI Sequence Viewer
	DAA04901	(Get FASTA)	NCBI Sequence Viewer
	EAW73676	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSP00000492971
	ENSP00000492971.1
GenBank Protein	Q6IEV9	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001004700 ⟸ NM_001004700

- UniProtKB:

B9EIL4 (UniProtKB/Swiss-Prot), Q8NGL8 (UniProtKB/Swiss-Prot), Q6IEV9 (UniProtKB/Swiss-Prot), A0A126GVN6 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MQQNNSVPEFILLGLTQDPLRQKIVFVIFLIFYMGTVVGNMLIIVTIKSSRTLGSPMYFFLFYL
SFADSCFSTSTAPRLIVDALSEKKIITYNECMTQVFALHLFGCMEIFVLILMAVDRYVAICKPL
RYPTIMSQQVCIILIVLAWIGSLIHSTAQIILALRLPFCGPYLIDHYCCDLQPLLKLACMDTYM
INLLLVSNSGAICSSSFMILIISYIVILHSLRNHSAKGKKKALSACTSHIIVVILFFGPCIFIY
TRPPTTFPMDKMVAVFYTIGTPFLNPLIYTLRNAEVKNAMRKLWHGKIISENKG

hide sequence

RefSeq Acc Id:

ENSP00000492971 ⟸ ENST00000641580

RefSeq Acc Id:

ENSP00000306651 ⟸ ENST00000302231

Protein Domains

G-protein coupled receptors family 1 profile

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q6IEV9-F1-model_v2	AlphaFold	Q6IEV9	1-310	view protein structure

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	HGNC:15167	AgrOrtholog
COSMIC	OR4C11	COSMIC
Ensembl Genes	ENSG00000172188	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENST00000641580	ENTREZGENE
	ENST00000641580.1	UniProtKB/Swiss-Prot
Gene3D-CATH	Rhodopsin 7-helix transmembrane proteins	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx	ENSG00000172188	GTEx
HGNC ID	HGNC:15167	ENTREZGENE
Human Proteome Map	OR4C11	Human Proteome Map
InterPro	GPCR_Rhodpsn	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	GPCR_Rhodpsn_7TM	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Olfact_rcpt	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	hsa:219429	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene	219429	ENTREZGENE
PANTHER	OLFACTORY RECEPTOR	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	OLFACTORY RECEPTOR 4C11	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	7tm_4	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB	PA32253	PharmGKB
PRINTS	GPCRRHODOPSN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	OLFACTORYR	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	G_PROTEIN_RECEP_F1_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	G_PROTEIN_RECEP_F1_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	Family A G protein-coupled receptor-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A126GVN6	ENTREZGENE, UniProtKB/TrEMBL
	B9EIL4	ENTREZGENE
	OR4CB_HUMAN	UniProtKB/Swiss-Prot, ENTREZGENE
	Q8NGL8	ENTREZGENE
UniProt Secondary	B9EIL4	UniProtKB/Swiss-Prot
	Q8NGL8	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-12-15	OR4C11	olfactory receptor family 4 subfamily C member 11		olfactory receptor, family 4, subfamily C, member 11	Symbol and/or name change	5135510	APPROVED
2011-09-01	OR4C11	olfactory receptor, family 4, subfamily C, member 11	OR4C11	olfactory receptor, family 4, subfamily C, member 11	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Human Phenotype Annotations - ClinVar

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Imported Disease Annotations - ClinVar

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