OR2D3 (olfactory receptor family 2 subfamily D member 3)

Gene: OR2D3 (olfactory receptor family 2 subfamily D member 3) Homo sapiens

Analyze

Symbol:

OR2D3

Name:

olfactory receptor family 2 subfamily D member 3

RGD ID:

1354348

HGNC Page

HGNC:15146

Description:

Predicted to enable olfactory receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception of smell. Predicted to be located in membrane. Predicted to be active in plasma membrane.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

olfactory receptor 2D3; olfactory receptor OR11-89; olfactory receptor, family 2, subfamily D, member 3; OR11-89

RGD Orthologs

Alliance Genes

More Info

more info ...

Allele / Splice:

See ClinVar data

Latest Assembly:

GRCh38 - Human Genome Assembly GRCh38

Position:

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	6,921,002 - 6,921,994 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	6,921,002 - 6,921,994 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	6,942,233 - 6,943,225 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	6,898,809 - 6,899,801 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	11	6,898,808 - 6,899,801	NCBI
Celera	11	7,061,307 - 7,062,299 (+)	NCBI		Celera
Cytogenetic Map	11	p15.4	NCBI
HuRef	11	6,600,833 - 6,601,825 (+)	NCBI		HuRef
CHM1_1	11	6,941,186 - 6,942,178 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	11	6,979,425 - 6,980,417 (+)	NCBI		T2T-CHM13v2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (IAGP)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

all-trans-retinoic acid (EXP)

atrazine (EXP)

benzo[a]pyrene (EXP)

bisphenol A (EXP,ISO)

fulvestrant (EXP)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

detection of chemical stimulus involved in sensory perception of smell (IBA,IEA)

G protein-coupled receptor signaling pathway (IEA)

sensory perception of smell (IEA)

signal transduction (IEA)

Cellular Component

membrane (IEA)

plasma membrane (IBA,IEA)

Molecular Function

G protein-coupled receptor activity (IEA)

olfactory receptor activity (IBA,IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12213199	PMID:12477932	PMID:14983052	PMID:21873635

Genomics

Comparative Map Data

OR2D3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	6,921,002 - 6,921,994 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	6,921,002 - 6,921,994 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	6,942,233 - 6,943,225 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	6,898,809 - 6,899,801 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	11	6,898,808 - 6,899,801	NCBI
Celera	11	7,061,307 - 7,062,299 (+)	NCBI		Celera
Cytogenetic Map	11	p15.4	NCBI
HuRef	11	6,600,833 - 6,601,825 (+)	NCBI		HuRef
CHM1_1	11	6,941,186 - 6,942,178 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	11	6,979,425 - 6,980,417 (+)	NCBI		T2T-CHM13v2.0

Or2d36
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	106,746,505 - 106,747,536 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	106,737,534 - 106,749,788 (+)	Ensembl		GRCm39 Ensembl
GRCm38	7	107,147,298 - 107,148,329 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	107,138,327 - 107,150,581 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	114,290,832 - 114,291,776 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	106,938,495 - 106,939,439 (+)	NCBI		MGSCv36	mm8
Celera	7	107,143,715 - 107,144,659 (+)	NCBI		Celera
Cytogenetic Map	7	E3	NCBI
cM Map	7	56.1	NCBI

Or2d36
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	170,439,985 - 170,440,929 (+)	NCBI		GRCr8
mRatBN7.2	1	161,028,174 - 161,029,118 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	161,020,256 - 161,029,717 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	169,300,781 - 169,301,725 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	176,486,791 - 176,487,735 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	169,171,008 - 169,171,952 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	171,274,305 - 171,275,249 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	171,274,305 - 171,275,249 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	178,279,343 - 178,280,287 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	164,459,852 - 164,460,796 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	164,555,328 - 164,556,273 (+)	NCBI
Celera	1	158,941,819 - 158,942,763 (+)	NCBI		Celera
Cytogenetic Map	1	q33	NCBI

LOC102014349
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955414	22,824,126 - 22,825,094 (+)	NCBI	ChiLan1.0	ChiLan1.0

LOC100975556
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	9,325,841 - 9,328,957 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	9,291,247 - 9,294,364 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	7,023,410 - 7,024,467 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	6,706,475 - 6,707,532 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	6,706,497 - 6,707,489 (+)	Ensembl	panpan1.1		panPan2

OR2D3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	21	30,508,243 - 30,509,187 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	21	30,508,243 - 30,509,187 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	21	30,144,145 - 30,145,089 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	21	31,322,387 - 31,323,331 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	21	31,322,387 - 31,323,331 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	21	30,638,385 - 30,639,329 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	21	30,804,147 - 30,805,091 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	21	30,999,456 - 31,000,400 (+)	NCBI		UU_Cfam_GSD_1.0

LOC106145523
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	55,489,523 - 55,490,438 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004937087	129,722 - 130,637 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LOC100738683
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	9	2,829,615 - 2,835,156 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	3,344,439 - 3,345,941 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

LOC103241143
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	57,890,924 - 57,893,405 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	57,891,612 - 57,892,604 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	155,650,321 - 155,651,858 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

LOC101700372
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624817	8,746,684 - 8,747,616 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624817	8,746,657 - 8,747,616 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in OR2D3
13 total Variants

Clinical Variants

Name	Type	Condition(s)	Position(s)	Clinical significance
GRCh38/hg38 11p15.4(chr11:3745061-7846057)x3	copy number gain	See cases [RCV000053616]	Chr11:3745061..7846057 [GRCh38] Chr11:3766291..7867604 [GRCh37] Chr11:3722867..7824180 [NCBI36] Chr11:11p15.4	pathogenic
GRCh38/hg38 11p15.5-13(chr11:202758-31726224)x3	copy number gain	See cases [RCV000053613]	Chr11:202758..31726224 [GRCh38] Chr11:202758..31747772 [GRCh37] Chr11:192758..31704348 [NCBI36] Chr11:11p15.5-13	pathogenic
NM_001004684.1(OR2D3):c.661G>A (p.Val221Ile)	single nucleotide variant	Malignant melanoma [RCV000069654]	Chr11:6921662 [GRCh38] Chr11:6942893 [GRCh37] Chr11:6899469 [NCBI36] Chr11:11p15.4	not provided
NM_001004684.1(OR2D3):c.965G>A (p.Gly322Glu)	single nucleotide variant	Malignant melanoma [RCV000069655]	Chr11:6921966 [GRCh38] Chr11:6943197 [GRCh37] Chr11:6899773 [NCBI36] Chr11:11p15.4	not provided
GRCh38/hg38 11p15.5-15.1(chr11:446754-18904742)x3	copy number gain	See cases [RCV000133997]	Chr11:446754..18904742 [GRCh38] Chr11:446754..18926289 [GRCh37] Chr11:436754..18882865 [NCBI36] Chr11:11p15.5-15.1	pathogenic
GRCh38/hg38 11p15.5-15.4(chr11:61793-10727969)x3	copy number gain	See cases [RCV000139987]	Chr11:61793..10727969 [GRCh38] Chr11:61793..10749516 [GRCh37] Chr11:51793..10706092 [NCBI36] Chr11:11p15.5-15.4	pathogenic
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470)	copy number gain	See cases [RCV000511729]	Chr11:230616..134938470 [GRCh37] Chr11:11p15.5-q25	pathogenic
GRCh37/hg19 11p15.5-12(chr11:230615-37698540)x3	copy number gain	See cases [RCV000511561]	Chr11:230615..37698540 [GRCh37] Chr11:11p15.5-12	pathogenic
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470)x3	copy number gain	See cases [RCV000510881]	Chr11:230616..134938470 [GRCh37] Chr11:11p15.5-q25	pathogenic
GRCh37/hg19 11p15.5-15.3(chr11:193146-12643136)	copy number gain	Silver-Russell syndrome 1 [RCV000767567]	Chr11:193146..12643136 [GRCh37] Chr11:11p15.5-15.3	pathogenic
GRCh37/hg19 11p15.5-14.3(chr11:230615-25584362)x3	copy number gain	See cases [RCV000512225]	Chr11:230615..25584362 [GRCh37] Chr11:11p15.5-14.3	pathogenic
GRCh37/hg19 11p15.5-13(chr11:230615-31995219)x3	copy number gain	See cases [RCV000512477]	Chr11:230615..31995219 [GRCh37] Chr11:11p15.5-13	pathogenic
GRCh37/hg19 11p15.4(chr11:6905914-7062692)x1	copy number loss	not provided [RCV000683310]	Chr11:6905914..7062692 [GRCh37] Chr11:11p15.4	uncertain significance
GRCh37/hg19 11p15.5-15.4(chr11:230615-9704511)x3	copy number gain	not provided [RCV000683369]	Chr11:230615..9704511 [GRCh37] Chr11:11p15.5-15.4	pathogenic
GRCh37/hg19 11p15.5-15.1(chr11:230615-17099213)x3	copy number gain	not provided [RCV000683372]	Chr11:230615..17099213 [GRCh37] Chr11:11p15.5-15.1	pathogenic
GRCh37/hg19 11p15.5-q25(chr11:198510-134934063)x3	copy number gain	not provided [RCV000737348]	Chr11:198510..134934063 [GRCh37] Chr11:11p15.5-q25	pathogenic
GRCh37/hg19 11p15.5-q25(chr11:70864-134938470)x3	copy number gain	not provided [RCV000749874]	Chr11:70864..134938470 [GRCh37] Chr11:11p15.5-q25	pathogenic
GRCh37/hg19 11p15.4(chr11:6851550-6984119)x1	copy number loss	not provided [RCV000856656]	Chr11:6851550..6984119 [GRCh37] Chr11:11p15.4	uncertain significance
GRCh37/hg19 11p15.4(chr11:6908898-7058885)x1	copy number loss	not provided [RCV000847040]	Chr11:6908898..7058885 [GRCh37] Chr11:11p15.4	uncertain significance
GRCh37/hg19 11p15.4(chr11:6754444-6982365)x1	copy number loss	not provided [RCV000846230]	Chr11:6754444..6982365 [GRCh37] Chr11:11p15.4	uncertain significance
NM_001004684.1(OR2D3):c.543T>A (p.His181Gln)	single nucleotide variant	Inborn genetic diseases [RCV003248939]	Chr11:6921544 [GRCh38] Chr11:6942775 [GRCh37] Chr11:11p15.4	likely benign
GRCh37/hg19 11p15.5-13(chr11:235934-33826995)x3	copy number gain	not provided [RCV001006372]	Chr11:235934..33826995 [GRCh37] Chr11:11p15.5-13	pathogenic
GRCh37/hg19 11p15.4(chr11:6890900-6969676)x1	copy number loss	not provided [RCV001006382]	Chr11:6890900..6969676 [GRCh37] Chr11:11p15.4	uncertain significance
GRCh37/hg19 11p15.5-15.4(chr11:210300-8664358)x3	copy number gain	Silver-Russell syndrome 1 [RCV001263222]	Chr11:210300..8664358 [GRCh37] Chr11:11p15.5-15.4	pathogenic
GRCh37/hg19 11p15.4(chr11:6502523-7248333)x3	copy number gain	not provided [RCV001836564]	Chr11:6502523..7248333 [GRCh37] Chr11:11p15.4	uncertain significance
GRCh37/hg19 11p15.5-14.2(chr11:230615-26881146)x3	copy number gain	See cases [RCV002286351]	Chr11:230615..26881146 [GRCh37] Chr11:11p15.5-14.2	pathogenic
GRCh37/hg19 11p15.5-15.4(chr11:230616-8250724)x3	copy number gain	not provided [RCV002472435]	Chr11:230616..8250724 [GRCh37] Chr11:11p15.5-15.4	pathogenic
NM_001004684.1(OR2D3):c.449C>T (p.Thr150Ile)	single nucleotide variant	Inborn genetic diseases [RCV002969929]	Chr11:6921450 [GRCh38] Chr11:6942681 [GRCh37] Chr11:11p15.4	uncertain significance
NM_001004684.1(OR2D3):c.644T>C (p.Ile215Thr)	single nucleotide variant	Inborn genetic diseases [RCV002729542]	Chr11:6921645 [GRCh38] Chr11:6942876 [GRCh37] Chr11:11p15.4	uncertain significance
NM_001004684.1(OR2D3):c.154C>G (p.Leu52Val)	single nucleotide variant	Inborn genetic diseases [RCV002798485]	Chr11:6921155 [GRCh38] Chr11:6942386 [GRCh37] Chr11:11p15.4	uncertain significance
NM_001004684.1(OR2D3):c.286C>A (p.Gln96Lys)	single nucleotide variant	Inborn genetic diseases [RCV002822150]	Chr11:6921287 [GRCh38] Chr11:6942518 [GRCh37] Chr11:11p15.4	uncertain significance
NM_001004684.1(OR2D3):c.106G>C (p.Asp36His)	single nucleotide variant	Inborn genetic diseases [RCV002887447]	Chr11:6921107 [GRCh38] Chr11:6942338 [GRCh37] Chr11:11p15.4	uncertain significance
NM_001004684.1(OR2D3):c.527C>G (p.Thr176Ser)	single nucleotide variant	Inborn genetic diseases [RCV002765008]	Chr11:6921528 [GRCh38] Chr11:6942759 [GRCh37] Chr11:11p15.4	uncertain significance
NM_001004684.1(OR2D3):c.314G>A (p.Arg105Lys)	single nucleotide variant	Inborn genetic diseases [RCV002941265]	Chr11:6921315 [GRCh38] Chr11:6942546 [GRCh37] Chr11:11p15.4	uncertain significance
NM_001004684.1(OR2D3):c.742G>A (p.Glu248Lys)	single nucleotide variant	Inborn genetic diseases [RCV002935173]	Chr11:6921743 [GRCh38] Chr11:6942974 [GRCh37] Chr11:11p15.4	uncertain significance
NM_001004684.1(OR2D3):c.970A>G (p.Lys324Glu)	single nucleotide variant	Inborn genetic diseases [RCV002944668]	Chr11:6921971 [GRCh38] Chr11:6943202 [GRCh37] Chr11:11p15.4	uncertain significance
NM_001004684.1(OR2D3):c.796C>G (p.Leu266Val)	single nucleotide variant	Inborn genetic diseases [RCV003178221]	Chr11:6921797 [GRCh38] Chr11:6943028 [GRCh37] Chr11:11p15.4	uncertain significance
GRCh37/hg19 11p15.4(chr11:6801941-7136661)x3	copy number gain	not provided [RCV003484831]	Chr11:6801941..7136661 [GRCh37] Chr11:11p15.4	uncertain significance
GRCh37/hg19 11p15.5-15.4(chr11:230615-8821443)x3	copy number gain	Russell-Silver syndrome [RCV003444025]	Chr11:230615..8821443 [GRCh37] Chr11:11p15.5-15.4	pathogenic

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	44
Count of miRNA genes:	42
Interacting mature miRNAs:	44
Transcripts:	ENST00000317834
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region

OR2D3__5999

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	11	6,942,579 - 6,943,304	UniSTS	GRCh37
Build 36	11	6,899,155 - 6,899,880	RGD	NCBI36
Celera	11	7,061,653 - 7,062,378	RGD
HuRef	11	6,601,179 - 6,601,904	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system

circulatory system

endocrine system

exocrine system

hemolymphoid system

hepatobiliary system

integumental system

musculoskeletal system

nervous system

renal system

reproductive system

respiratory system

sensory system

adipose tissue

appendage

High

Medium

Low

Below cutoff

234

245

185

200

334

129

388

427

212

203

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001004684	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB065825	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC090160	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF399592	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC137208	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC137209	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BK004294	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH471064	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CP068267	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KP290410	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENST00000317834 ⟹ ENSP00000320560

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	11	6,921,002 - 6,921,994 (+)	Ensembl

RefSeq Acc Id:

NM_001004684 ⟹ NP_001004684

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	11	6,921,002 - 6,921,994 (+)	NCBI
GRCh37	11	6,942,233 - 6,943,225 (+)	RGD
Build 36	11	6,898,809 - 6,899,801 (+)	NCBI Archive
Celera	11	7,061,307 - 7,062,299 (+)	RGD
HuRef	11	6,600,833 - 6,601,825 (+)	RGD
CHM1_1	11	6,941,186 - 6,942,178 (+)	NCBI
T2T-CHM13v2.0	11	6,979,425 - 6,980,417 (+)	NCBI

Sequence:

show sequence

ATGTGTTCTTTTTTCTTGTGCCAAACAGGTAAACAGGCAAAAATATCAATGGGAGAAGAAAACC
AAACCTTTGTGTCCAAGTTTATCTTCCTGGGTCTTTCACAGGACTTGCAGACCCAGATCCTGCT
ATTTATCCTTTTCCTCATCATTTATCTGCTGACCGTGCTTGGAAACCAGCTCATCATCATTCTC
ATCTTCCTGGATTCTCGCCTTCACACTCCCATGTATTTTTTTCTTAGAAATCTCTCCTTTGCAG
ATCTCTGTTTCTCTACTAGCATTGTCCCTCAAGTGTTGGTTCACTTCTTGGTAAAGAGGAAAAC
CATTTCTTTTTATGGGTGTATGACACAGATAATTGTCTTTCTTCTGGTTGGGTGTACAGAGTGT
GCGCTGCTGGCAGTGATGTCCTATGACCGGTATGTGGCTGTCTGCAAGCCCCTGTACTACTCTA
CCATCATGACACAACGGGTGTGTCTCTGGCTGTCCTTCAGGTCCTGGGCCAGTGGGGCACTAGT
GTCTTTAGTAGATACCAGCTTTACTTTCCATCTTCCCTACTGGGGACAGAATATAATCAATCAC
TACTTTTGTGAACCTCCTGCCCTCCTGAAGCTGGCTTCCATAGACACTTACAGCACAGAAATGG
CCATCTTTTCAATGGGCGTGGTAATCCTCCTGGCCCCTGTCTCCCTGATTCTTGGTTCTTATTG
GAATATTATCTCCACTGTTATCCAGATGCAGTCTGGGGAAGGGAGACTCAAGGCTTTTTCCACC
TGTGGCTCCCATCTTATTGTTGTTGTCCTCTTCTATGGGTCAGGAATATTCACCTACATGCGAC
CAAACTCCAAGACTACAAAAGAACTGGATAAAATGATATCTGTGTTCTATACAGCGGTGACTCC
AATGTTGAACCCCATAATTTATAGCTTGAGGAACAAAGATGTCAAAGGGGCTCTCAGGAAACTA
GTTGGGAGAAAGTGCTTCTCTCATAGGCAGTGA

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Protein Sequences


Protein RefSeqs	NP_001004684	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI37209	(Get FASTA)	NCBI Sequence Viewer
	AAI37210	(Get FASTA)	NCBI Sequence Viewer
	AAK95077	(Get FASTA)	NCBI Sequence Viewer
	ALI87578	(Get FASTA)	NCBI Sequence Viewer
	BAC06044	(Get FASTA)	NCBI Sequence Viewer
	DAA04692	(Get FASTA)	NCBI Sequence Viewer
	EAW68672	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSP00000320560
	ENSP00000320560.3
GenBank Protein	Q8NGH3	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001004684 ⟸ NM_001004684

- UniProtKB:

Q6IFG8 (UniProtKB/Swiss-Prot), B2RP06 (UniProtKB/Swiss-Prot), Q96R51 (UniProtKB/Swiss-Prot), Q8NGH3 (UniProtKB/Swiss-Prot), A0A126GW08 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MCSFFLCQTGKQAKISMGEENQTFVSKFIFLGLSQDLQTQILLFILFLIIYLLTVLGNQLIIIL
IFLDSRLHTPMYFFLRNLSFADLCFSTSIVPQVLVHFLVKRKTISFYGCMTQIIVFLLVGCTEC
ALLAVMSYDRYVAVCKPLYYSTIMTQRVCLWLSFRSWASGALVSLVDTSFTFHLPYWGQNIINH
YFCEPPALLKLASIDTYSTEMAIFSMGVVILLAPVSLILGSYWNIISTVIQMQSGEGRLKAFST
CGSHLIVVVLFYGSGIFTYMRPNSKTTKELDKMISVFYTAVTPMLNPIIYSLRNKDVKGALRKL
VGRKCFSHRQ

hide sequence

RefSeq Acc Id:

ENSP00000320560 ⟸ ENST00000317834

Protein Domains

G-protein coupled receptors family 1 profile

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q8NGH3-F1-model_v2	AlphaFold	Q8NGH3	1-330	view protein structure

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	HGNC:15146	AgrOrtholog
COSMIC	OR2D3	COSMIC
Ensembl Genes	ENSG00000178358	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENST00000317834	ENTREZGENE
	ENST00000317834.5	UniProtKB/Swiss-Prot
Gene3D-CATH	Rhodopsin 7-helix transmembrane proteins	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx	ENSG00000178358	GTEx
HGNC ID	HGNC:15146	ENTREZGENE
Human Proteome Map	OR2D3	Human Proteome Map
InterPro	GPCR_Rhodpsn	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	GPCR_Rhodpsn_7TM	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Olfact_rcpt	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	hsa:120775	UniProtKB/Swiss-Prot
NCBI Gene	120775	ENTREZGENE
PANTHER	OLFACTORY RECEPTOR	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	OLFACTORY RECEPTOR 2D3	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	7tm_4	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB	PA32153	PharmGKB
PRINTS	GPCRRHODOPSN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	OLFACTORYR	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	G_PROTEIN_RECEP_F1_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	G_PROTEIN_RECEP_F1_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	Family A G protein-coupled receptor-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A126GW08	ENTREZGENE, UniProtKB/TrEMBL
	B2RP06	ENTREZGENE
	OR2D3_HUMAN	UniProtKB/Swiss-Prot
	Q6IFG8	ENTREZGENE
	Q8NGH3	ENTREZGENE
	Q96R51	ENTREZGENE
UniProt Secondary	B2RP06	UniProtKB/Swiss-Prot
	Q6IFG8	UniProtKB/Swiss-Prot
	Q96R51	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-12-15	OR2D3	olfactory receptor family 2 subfamily D member 3	OR2D3	olfactory receptor, family 2, subfamily D, member 3	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar