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Gene: LAS1L (LAS1 like ribosome biogenesis factor) Homo sapiens
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Symbol: LAS1L
Name: LAS1 like ribosome biogenesis factor
Description: Exhibits RNA binding activity. Predicted to be involved in maturation of 5.8S rRNA and maturation of LSU-rRNA. Localizes to MLL1 complex. Implicated in Wilson-Turner syndrome; INTERACTS WITH bisphenol A; carbamazepine; cyclosporin A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: dJ475B7.2; FLJ12525; FLJ30133; FLJ45274; Las1; LAS1 like, ribosome biogenesis factor; Las1-like; LAS1-like, ribosome biogenesis factor; protein LAS1 homolog; ribosomal biogenesis protein LAS1L; RP3-475B7.2; WTS
Orthologs:
Mus musculus (house mouse) : Las1l (LAS1-like (S. cerevisiae))  MGI  Alliance
Rattus norvegicus (Norway rat) : Las1l (LAS1-like, ribosome biogenesis factor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Las1l (LAS1 like ribosome biogenesis factor)
Pan paniscus (bonobo/pygmy chimpanzee) : LAS1L (LAS1 like ribosome biogenesis factor)
Canis lupus familiaris (dog) : LAS1L (LAS1 like ribosome biogenesis factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Las1l (LAS1 like ribosome biogenesis factor)
Sus scrofa (pig) : LAS1L (LAS1 like ribosome biogenesis factor)
Chlorocebus sabaeus (African green monkey) : LAS1L (LAS1 like ribosome biogenesis factor)
Heterocephalus glaber (naked mole-rat) : Las1l (LAS1 like ribosome biogenesis factor)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 EnsemblX65,512,582 - 65,534,775 (-)EnsemblGRCh38hg38GRCh38
GRCh38X65,512,582 - 65,534,806 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X64,732,462 - 64,754,686 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X64,649,191 - 64,671,392 (-)NCBINCBI36hg18NCBI36
Build 34X64,515,488 - 64,537,688NCBI
CeleraX65,079,606 - 65,101,830 (-)NCBI
Cytogenetic MapXq12NCBI
HuRefX58,560,622 - 58,582,851 (-)NCBIHuRef
CHM1_1X64,625,528 - 64,647,714 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on LAS1L
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1354295
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.