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Gene: MED28 (mediator complex subunit 28) Homo sapiens
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Symbol: MED28
Name: mediator complex subunit 28
Description: Predicted to have actin binding activity. Predicted to be involved in negative regulation of smooth muscle cell differentiation and stem cell population maintenance. Localizes to nucleoplasm; PARTICIPATES IN RNA polymerase II transcription pathway; INTERACTS WITH (S)-nicotine; 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one; 2-methylcholine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1500003D12Rik; DKFZp434N185; EG1; endothelial-derived gene 1; endothelial-derived protein 1; magicin; mediator of RNA polymerase II transcription subunit 28; mediator of RNA polymerase II transcription, subunit 28 homolog; mediator of rna polymerase ii transcription, subunit 28 homolog (yeast); merlin and Grb2-interacting cytoskeletal protein; tumor angiogenesis marker EG-1
Orthologs:
Mus musculus (house mouse) : Med28 (mediator complex subunit 28)  MGI  Alliance
Rattus norvegicus (Norway rat) : Med28 (mediator complex subunit 28)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Med28 (mediator complex subunit 28)
Pan paniscus (bonobo/pygmy chimpanzee) : MED28 (mediator complex subunit 28)
Canis lupus familiaris (dog) : MED28 (mediator complex subunit 28)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Med28 (mediator complex subunit 28)
Sus scrofa (pig) : MED28 (mediator complex subunit 28)
Chlorocebus sabaeus (African green monkey) : MED28 (mediator complex subunit 28)
Heterocephalus glaber (naked mole-rat) : Med28 (mediator complex subunit 28)
more info ...
Related Pseudogenes: MED28P1   MED28P2   MED28P3   MED28P4   MED28P5   MED28P6   MED28P7  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl417,614,641 - 17,634,105 (+)EnsemblGRCh38hg38GRCh38
GRCh38417,614,641 - 17,634,105 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37417,616,273 - 17,626,160 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36417,225,371 - 17,235,258 (+)NCBINCBI36hg18NCBI36
Build 34417,292,541 - 17,302,429NCBI
Celera418,081,269 - 18,091,156 (+)NCBI
Cytogenetic Map4p15.32NCBI
HuRef416,970,862 - 16,980,711 (+)NCBIHuRef
CHM1_1417,614,231 - 17,625,232 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
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Clinical Variants

Additional Information

External Database Links
 
More on MED28
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1354293
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-07-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.