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Gene: MAST1 (microtubule associated serine/threonine kinase 1) Homo sapiens
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Symbol: MAST1
Name: microtubule associated serine/threonine kinase 1
Description: This gene is a member of the microtubule-associated serine/threonine kinase (MAST) family. The protein encoded by this gene has an N-terminal serine/threonine kinase domain followed by a postsynaptic density protein-95/discs large/zona occludens-1 (PDZ) domain. In mouse and rat, the orthologous protein associates with the cytoskeleton and can bind both beta-2-syntrophin and neuronal nitric oxide synthase (nNOS) through its PDZ domain. In mouse and rat, this protein also co-localizes with dystrophin- and utrophin-associated protein complexes (DAPC/UAPC) in the vascular endothelium of the central nervous system. [provided by RefSeq, May 2017]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: KIAA0973; MCCCHCM; microtubule-associated serine/threonine-protein kinase 1; SAST; SAST170; syntrophin associated serine/threonine kinase; syntrophin-associated serine/threonine-protein kinase
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381912,838,515 - 12,874,952 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371912,949,259 - 12,985,766 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361912,810,348 - 12,846,765 (+)NCBINCBI36hg18NCBI36
Build 341912,810,347 - 12,846,765NCBI
Celera1912,838,964 - 12,875,474 (+)NCBI
Cytogenetic Map19p13.13NCBI
HuRef1912,520,853 - 12,557,622 (+)NCBIHuRef
CHM1_11912,949,779 - 12,986,286 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on MAST1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1354102
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.