TMPRSS2 (transmembrane serine protease 2) - Rat Genome Database

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Gene: TMPRSS2 (transmembrane serine protease 2) Homo sapiens
Analyze
Symbol: TMPRSS2
Name: transmembrane serine protease 2
RGD ID: 1354092
HGNC Page HGNC
Description: Predicted to enable serine-type endopeptidase activity. Involved in positive regulation of viral entry into host cell and protein autoprocessing. Located in nucleoplasm and plasma membrane. Biomarker of prostate adenocarcinoma and prostatic hypertrophy.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: epitheliasin; FLJ41954; PP9284; PRSS10; serine protease 10; transmembrane protease serine 2; transmembrane protease, serine 2
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
NCBI Annotation Information: Note: This gene has been reviewed for its involvement in coronavirus biology, and is involved in SARS-CoV-2 infection.
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2141,464,300 - 41,531,116 (-)EnsemblGRCh38hg38GRCh38
GRCh382141,464,305 - 41,508,158 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372142,836,232 - 42,880,085 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362141,758,351 - 41,801,948 (-)NCBINCBI36hg18NCBI36
Build 342141,758,350 - 41,801,948NCBI
Celera2128,034,659 - 28,078,450 (-)NCBI
Cytogenetic Map21q22.3NCBI
HuRef2128,305,352 - 28,349,365 (-)NCBIHuRef
CHM1_12142,397,265 - 42,440,908 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (ISO)
1,2-dichloroethane  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (EXP)
17beta-hydroxy-5alpha-androstan-3-one  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP,ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (ISO)
acetic acid [4-[2-(dimethylamino)ethoxy]-2-methyl-5-propan-2-ylphenyl] ester  (EXP)
afimoxifene  (EXP)
aflatoxin B1  (EXP,ISO)
ajmaline  (EXP)
all-trans-retinoic acid  (EXP)
all-trans-retinol  (EXP)
allopurinol  (EXP)
amitriptyline  (EXP)
ammonium chloride  (ISO)
amphotericin B  (EXP)
azathioprine  (EXP,ISO)
benzbromarone  (EXP)
benzo[a]pyrene  (EXP,ISO)
Benzo[ghi]perylene  (ISO)
bicalutamide  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
buspirone  (EXP)
cadmium dichloride  (ISO)
calcitriol  (EXP)
camostat  (EXP)
carbamazepine  (EXP)
carbon nanotube  (ISO)
celastrol  (EXP)
chloramphenicol  (EXP)
chlordecone  (ISO)
Chlormadinone acetate  (EXP)
chlorphenamine  (EXP)
chlorpromazine  (EXP)
choline  (ISO)
ciprofloxacin  (EXP)
curcumin  (EXP)
cyclophosphamide  (EXP,ISO)
cyclosporin A  (EXP)
danazol  (EXP,ISO)
dapsone  (EXP)
decabromodiphenyl ether  (ISO)
dexamethasone  (EXP)
diazepam  (EXP)
diazinon  (EXP)
diclofenac  (EXP)
dicrotophos  (EXP)
dioxygen  (ISO)
disopyramide  (EXP)
dorsomorphin  (EXP)
doxepin  (EXP,ISO)
doxorubicin  (EXP,ISO)
dutasteride  (EXP)
elemental selenium  (EXP)
entinostat  (EXP)
enzalutamide  (EXP)
ethambutol  (EXP)
etoposide  (EXP)
famotidine  (EXP)
fentin acetate  (EXP)
flavonoids  (ISO)
fluphenazine  (EXP,ISO)
flutamide  (EXP)
folic acid  (ISO)
furan  (ISO)
gedunin  (EXP)
gemfibrozil  (EXP)
genistein  (EXP)
glyburide  (EXP)
Goserelin  (EXP)
haloperidol  (EXP,ISO)
hydrogen peroxide  (EXP)
hydroxyzine  (EXP)
imipramine  (EXP)
indometacin  (EXP)
isoniazide  (EXP)
ketoconazole  (EXP)
L-methionine  (ISO)
lithium chloride  (EXP)
metformin  (EXP)
methylisothiazolinone  (EXP)
methylseleninic acid  (EXP)
mexiletine  (EXP)
monosodium L-glutamate  (ISO)
N-acetyl-1,4-benzoquinone imine  (EXP)
N-acetyl-L-cysteine  (EXP)
naproxen  (EXP)
nickel atom  (EXP)
nimesulide  (EXP,ISO)
nitrofurantoin  (EXP)
omeprazole  (EXP,ISO)
ozone  (EXP)
palbociclib  (EXP)
papaverine  (EXP)
paracetamol  (EXP,ISO)
paraquat  (ISO)
PCB138  (ISO)
perhexiline  (EXP)
phenobarbital  (EXP,ISO)
phenylmercury acetate  (EXP)
pirinixic acid  (ISO)
poly(I:C)  (ISO)
potassium dichromate  (ISO)
progesterone  (ISO)
promethazine  (EXP)
propiconazole  (ISO)
quinidine  (EXP)
raloxifene  (EXP)
resveratrol  (EXP)
rifampicin  (EXP,ISO)
Riluzole  (EXP)
SB 431542  (EXP)
selenium atom  (EXP)
simvastatin  (EXP)
sodium arsenite  (EXP)
sulfasalazine  (EXP)
sulindac  (EXP,ISO)
tamoxifen  (EXP,ISO)
testosterone  (EXP)
tetrachloromethane  (ISO)
tetramethrin  (EXP)
thapsigargin  (EXP)
theophylline  (EXP)
thioacetamide  (ISO)
ticlopidine  (EXP)
tolbutamide  (EXP)
trichostatin A  (EXP)
triphenyl phosphate  (ISO)
Triptolide  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (ISO)
zoledronic acid  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:8125298   PMID:9325052   PMID:10485450   PMID:10830953   PMID:11169526   PMID:11245484   PMID:11322890   PMID:11414763   PMID:12477932   PMID:15065083   PMID:15342556   PMID:15489334  
PMID:15537383   PMID:16254181   PMID:16575875   PMID:16585160   PMID:16820092   PMID:16973594   PMID:17032499   PMID:17207965   PMID:17367471   PMID:17390040   PMID:17584912   PMID:17632455  
PMID:17654723   PMID:17804708   PMID:18029348   PMID:18065961   PMID:18172298   PMID:18385909   PMID:18474293   PMID:18483239   PMID:18519767   PMID:18519769   PMID:18562527   PMID:18583469  
PMID:18676740   PMID:18694509   PMID:18922926   PMID:19029822   PMID:19056867   PMID:19147579   PMID:19158246   PMID:19190343   PMID:19199708   PMID:19242826   PMID:19396154   PMID:19465903  
PMID:19494719   PMID:19584163   PMID:19597533   PMID:19649210   PMID:19664128   PMID:19762545   PMID:19933109   PMID:20068566   PMID:20118910   PMID:20382709   PMID:20442300   PMID:20631123  
PMID:20798944   PMID:20800881   PMID:20878952   PMID:21036922   PMID:21040948   PMID:21068237   PMID:21123387   PMID:21169414   PMID:21325420   PMID:21377967   PMID:21394739   PMID:21499238  
PMID:21584900   PMID:21600800   PMID:21676887   PMID:21677539   PMID:21680704   PMID:21731703   PMID:21743434   PMID:21743959   PMID:21802835   PMID:21873635   PMID:21937078   PMID:22076164  
PMID:22222211   PMID:22313860   PMID:22558251   PMID:22674214   PMID:22736790   PMID:22860005   PMID:22930729   PMID:22993300   PMID:23192872   PMID:23352841   PMID:23376485   PMID:23447416  
PMID:23472063   PMID:23533145   PMID:23535644   PMID:23536651   PMID:23701505   PMID:23850495   PMID:24027332   PMID:24072184   PMID:24109594   PMID:24186205   PMID:24195515   PMID:24227843  
PMID:24292212   PMID:24297949   PMID:24418414   PMID:24529757   PMID:24777847   PMID:24789172   PMID:24824408   PMID:24926821   PMID:24931216   PMID:24961351   PMID:24997128   PMID:25007891  
PMID:25015038   PMID:25040002   PMID:25043536   PMID:25175909   PMID:25203900   PMID:25217961   PMID:25263440   PMID:25728532   PMID:25734995   PMID:25754347   PMID:25852077   PMID:25933120  
PMID:25939480   PMID:25977336   PMID:26018085   PMID:26026052   PMID:26167880   PMID:26251449   PMID:26379044   PMID:26424596   PMID:26503111   PMID:26615022   PMID:26774207   PMID:26978019  
PMID:27028521   PMID:27144529   PMID:27276682   PMID:27285981   PMID:27320318   PMID:27377958   PMID:27500376   PMID:27630329   PMID:27733646   PMID:27798103   PMID:27814612   PMID:27926866  
PMID:28004109   PMID:28050800   PMID:28364793   PMID:28445989   PMID:28611215   PMID:28633309   PMID:28783165   PMID:28845585   PMID:29127096   PMID:29277318   PMID:29346775   PMID:29773553  
PMID:30042415   PMID:30078722   PMID:30430607   PMID:30538195   PMID:30718921   PMID:30945288   PMID:31391268   PMID:31405024   PMID:31883084   PMID:32142651   PMID:32143573   PMID:32150281  
PMID:32229180   PMID:32246845   PMID:32296183   PMID:32329629   PMID:32333127   PMID:32333601   PMID:32404436   PMID:32410502   PMID:32441816   PMID:32467600   PMID:32468052   PMID:32480226  
PMID:32501810   PMID:32544566   PMID:32573479   PMID:32620366   PMID:32658591   PMID:32661206   PMID:32664879   PMID:32675312   PMID:32691890   PMID:32703421   PMID:32703818   PMID:32705281  
PMID:32726325   PMID:32759995   PMID:32768580   PMID:32776522   PMID:32828550   PMID:32831324   PMID:32840422   PMID:32842606   PMID:32851697   PMID:32861070   PMID:32861340   PMID:32867305  
PMID:32871104   PMID:32873700   PMID:32967703   PMID:32980345   PMID:33008593   PMID:33046696   PMID:33051876   PMID:33061814   PMID:33081421   PMID:33104520   PMID:33141952   PMID:33180746  
PMID:33188579   PMID:33207245   PMID:33243086   PMID:33245471   PMID:33268377   PMID:33278516   PMID:33289868   PMID:33301988   PMID:33315943   PMID:33351362   PMID:33358483   PMID:33375616  
PMID:33401657   PMID:33407110   PMID:33421977   PMID:33531686   PMID:33536584   PMID:33558541   PMID:33565463   PMID:33609069   PMID:33635001   PMID:33649313   PMID:33707526   PMID:33752217  
PMID:33755980   PMID:33789993   PMID:33812037   PMID:33828231   PMID:33844653   PMID:33921689   PMID:33958627   PMID:34001248   PMID:34045511   PMID:34159616   PMID:34160563   PMID:34168096  
PMID:34210968   PMID:34257580   PMID:34284028   PMID:34356057   PMID:34407143  


Genomics

Comparative Map Data
TMPRSS2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2141,464,300 - 41,531,116 (-)EnsemblGRCh38hg38GRCh38
GRCh382141,464,305 - 41,508,158 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372142,836,232 - 42,880,085 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362141,758,351 - 41,801,948 (-)NCBINCBI36hg18NCBI36
Build 342141,758,350 - 41,801,948NCBI
Celera2128,034,659 - 28,078,450 (-)NCBI
Cytogenetic Map21q22.3NCBI
HuRef2128,305,352 - 28,349,365 (-)NCBIHuRef
CHM1_12142,397,265 - 42,440,908 (-)NCBICHM1_1
Tmprss2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391697,365,882 - 97,460,741 (-)NCBIGRCm39mm39
GRCm39 Ensembl1697,365,882 - 97,412,395 (-)Ensembl
GRCm381697,564,682 - 97,659,541 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1697,564,682 - 97,611,195 (-)EnsemblGRCm38mm10GRCm38
MGSCv371697,786,289 - 97,832,802 (-)NCBIGRCm37mm9NCBIm37
MGSCv361697,719,598 - 97,766,111 (-)NCBImm8
Celera1698,625,511 - 98,672,561 (-)NCBICelera
Cytogenetic Map16C4NCBI
cM Map1657.53NCBI
Tmprss2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21136,934,306 - 36,973,779 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1136,934,306 - 36,973,715 (-)Ensembl
Rnor_6.01138,063,914 - 38,103,406 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1138,063,915 - 38,103,290 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01141,574,415 - 41,613,911 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41137,577,051 - 37,617,258 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11137,634,640 - 37,674,847 (-)NCBI
Celera1136,819,034 - 36,858,331 (-)NCBICelera
Cytogenetic Map11q12NCBI
Tmprss2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540740,957,122 - 40,976,644 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540740,958,562 - 40,985,415 (-)NCBIChiLan1.0ChiLan1.0
TMPRSS2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12141,128,358 - 41,170,924 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2141,131,515 - 41,161,088 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02127,800,466 - 27,843,395 (-)NCBIMhudiblu_PPA_v0panPan3
TMPRSS2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13135,933,082 - 35,968,732 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3135,087,922 - 35,123,133 (-)NCBI
ROS_Cfam_1.03135,451,094 - 35,486,696 (-)NCBI
UMICH_Zoey_3.13135,346,223 - 35,380,906 (-)NCBI
UNSW_CanFamBas_1.03135,325,381 - 35,360,709 (-)NCBI
UU_Cfam_GSD_1.03135,819,128 - 35,854,769 (-)NCBI
Tmprss2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497135,245,118 - 35,277,589 (-)NCBI
SpeTri2.0NW_0049365002,199,877 - 2,222,174 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TMPRSS2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13204,876,561 - 204,902,561 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113204,874,759 - 204,905,411 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213214,974,417 - 214,981,735 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TMPRSS2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1285,372,881 - 85,413,717 (-)NCBI
ChlSab1.1 Ensembl285,372,117 - 85,412,926 (-)Ensembl
Vero_WHO_p1.0NW_02366605413,228,416 - 13,267,943 (-)NCBI
Tmprss2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474528,565,515 - 28,593,102 (+)NCBI

Position Markers
PMC310729P10  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372142,865,802 - 42,865,986UniSTSGRCh37
Build 362141,787,672 - 41,787,856RGDNCBI36
Celera2128,064,179 - 28,064,363RGD
Cytogenetic Map21q22.3UniSTS
HuRef2128,335,085 - 28,335,269UniSTS
D21S1876  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372142,858,014 - 42,858,160UniSTSGRCh37
Build 362141,779,884 - 41,780,030RGDNCBI36
Celera2128,056,392 - 28,056,538RGD
Cytogenetic Map21q22.3UniSTS
HuRef2128,327,297 - 28,327,443UniSTS
TNG Radiation Hybrid Map2116410.0UniSTS
Stanford-G3 RH Map211434.0UniSTS
TMPRSS2_7892  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372142,836,288 - 42,837,188UniSTSGRCh37
Build 362141,758,158 - 41,759,058RGDNCBI36
Celera2128,034,469 - 28,035,369RGD
HuRef2128,305,162 - 28,306,062UniSTS
G29032  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372142,877,851 - 42,878,068UniSTSGRCh37
Build 362141,799,721 - 41,799,938RGDNCBI36
Celera2128,076,216 - 28,076,433RGD
Cytogenetic Map21q22.3UniSTS
HuRef2128,347,131 - 28,347,348UniSTS
SHGC-87658  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372142,836,587 - 42,836,709UniSTSGRCh37
Build 362141,758,457 - 41,758,579RGDNCBI36
Celera2128,034,768 - 28,034,890RGD
Cytogenetic Map21q22.3UniSTS
HuRef2128,305,461 - 28,305,583UniSTS
TNG Radiation Hybrid Map2116387.0UniSTS
GeneMap99-GB4 RH Map21221.95UniSTS
GDB:434012  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map21q22.2UniSTS
Cytogenetic Map3p24.2UniSTS
Cytogenetic Map7p14.1UniSTS
Cytogenetic Map5q31.2UniSTS
Cytogenetic Map1p36.32UniSTS
Cytogenetic Map2p25.1UniSTS
Cytogenetic Map22q11.22UniSTS
Cytogenetic Map14q32.3UniSTS
Cytogenetic Map19p13.2UniSTS
Cytogenetic Map17q11UniSTS
Cytogenetic Map17q21UniSTS
Cytogenetic Map9q34.13UniSTS
Cytogenetic Map10p13UniSTS
Cytogenetic Map3q27UniSTS
Cytogenetic Map14q22.3UniSTS
Cytogenetic Map7q22.1UniSTS
Cytogenetic Map9q34.3UniSTS
Cytogenetic Map4q32.2UniSTS
Cytogenetic Map1p34.2UniSTS
Cytogenetic Map12p13.31UniSTS
Cytogenetic Map3p21.1UniSTS
Cytogenetic Map10p15.3UniSTS
Cytogenetic Map19q13.13UniSTS
Cytogenetic Map17q21.33UniSTS
Cytogenetic Map22q13.33UniSTS
Cytogenetic Map5q23.3UniSTS
Cytogenetic Map16q22.1UniSTS
Cytogenetic Map12q24.13UniSTS
Cytogenetic MapXp11.23UniSTS
Cytogenetic Map19q13.3UniSTS
Cytogenetic Map9q34.11UniSTS
Cytogenetic Map1q24UniSTS
Cytogenetic Map16p11.2UniSTS
Cytogenetic Map14q24.3UniSTS
Cytogenetic Map19p13UniSTS
Cytogenetic Map7q21.13UniSTS
Cytogenetic Map19p13.3UniSTS
Cytogenetic Map17q22UniSTS
Cytogenetic Map2q31.2-q33.1UniSTS
Cytogenetic Map17q12UniSTS
Cytogenetic Map15q25.2UniSTS
Cytogenetic Map19q13.43UniSTS
Cytogenetic Map2p13.1UniSTS
Cytogenetic Map5q35.3UniSTS
Cytogenetic Map1p36.13UniSTS
Cytogenetic Map19q13.12UniSTS
Cytogenetic Map2p13.3UniSTS
Cytogenetic Map20q13.13UniSTS
Cytogenetic Map16q24UniSTS
Cytogenetic Map19q13UniSTS
Cytogenetic Map8p11.21UniSTS
Cytogenetic Map14q32.33UniSTS
Cytogenetic Map8q24.11UniSTS
Cytogenetic Map10q23.1UniSTS
Cytogenetic Map4q12UniSTS
Cytogenetic Map17p13.2UniSTS
Cytogenetic Map2q13UniSTS
Cytogenetic Map2p11.2UniSTS
Cytogenetic Map5q31.1UniSTS
Cytogenetic MapYp11.2UniSTS
Cytogenetic Map1q23.1UniSTS
Cytogenetic Map1q21.3UniSTS
Cytogenetic Map8p11.22UniSTS
Cytogenetic Map19q13.32UniSTS
Cytogenetic Map4q28.2UniSTS
Cytogenetic Map22q12.3UniSTS
Cytogenetic Map18p11.21UniSTS
Cytogenetic Map19p13.11UniSTS
Cytogenetic Map1p32.3UniSTS
Cytogenetic Map9p13.2UniSTS
Cytogenetic Map17q25UniSTS
Cytogenetic Map17q21.31UniSTS
Cytogenetic Map11p13UniSTS
Cytogenetic Map5q21UniSTS
Cytogenetic Map13q12.11UniSTS
Cytogenetic Map1q22UniSTS
Cytogenetic Map1p22.1UniSTS
Cytogenetic Map1p36.21UniSTS
Cytogenetic Map9q13-q21UniSTS
Cytogenetic Map16p13.3UniSTS
Cytogenetic Map7q22UniSTS
Cytogenetic Map8q24UniSTS
Cytogenetic Map7q36.1UniSTS
Cytogenetic Map2p15UniSTS
Cytogenetic Map4p16.3UniSTS
Cytogenetic Map3p25.3UniSTS
Cytogenetic Map2p23.3UniSTS
Cytogenetic Map8q24.3UniSTS
Cytogenetic Map17p13.3UniSTS
Cytogenetic Map5q33.3UniSTS
Cytogenetic Map21q22.3UniSTS
Cytogenetic Map3q26.2UniSTS
Cytogenetic Map3q23UniSTS
Cytogenetic Map5q32UniSTS
Cytogenetic Map17q21.1UniSTS
Cytogenetic Map15q21UniSTS
Cytogenetic Map6p21.3UniSTS
Cytogenetic Map17q11.2UniSTS
Cytogenetic Map8p11.2UniSTS
Cytogenetic Map17q24UniSTS
Cytogenetic Map19q13.3-q13.4UniSTS
Cytogenetic Map15q11.2UniSTS
Cytogenetic Map22q11.23UniSTS
Cytogenetic Map1p35.3UniSTS
Cytogenetic Map2q33-q34UniSTS
Cytogenetic Map17q25.2UniSTS
Cytogenetic Map1p35.1UniSTS
Cytogenetic Map22q11.2UniSTS
Cytogenetic Map2p16.1UniSTS
Cytogenetic Map1p36.22UniSTS
Cytogenetic Map11q23.1UniSTS
Cytogenetic Map22q13.1UniSTS
Cytogenetic Map12p13.2UniSTS
Cytogenetic Map22q11.21UniSTS
Cytogenetic Map7q21.3UniSTS
Cytogenetic Map1p36.11UniSTS
Cytogenetic Map5q13.2UniSTS
Cytogenetic Map10q11.22UniSTS
Cytogenetic Map3p25.1UniSTS
Cytogenetic Map22q13.2UniSTS
Cytogenetic Map1p13.3UniSTS
Cytogenetic Map1p21.3-p13.1UniSTS
Cytogenetic Map11q13.2UniSTS
Cytogenetic Map7q11.23UniSTS
Cytogenetic Map12q13.3UniSTS
Cytogenetic Map3q26.33UniSTS
Cytogenetic Map10q26.13UniSTS
Cytogenetic Map7p22UniSTS
Cytogenetic Map11q13UniSTS
Cytogenetic Map7q21-q22UniSTS
Cytogenetic Map17q25.3UniSTS
Cytogenetic Map19q13.33UniSTS
Cytogenetic Map4q22.1UniSTS
Cytogenetic Map20p13UniSTS
Cytogenetic Map16p13.12UniSTS
Cytogenetic Map5q12.3UniSTS
Cytogenetic Map2q33.2UniSTS
Cytogenetic Map6p22.3-p22.1UniSTS
Cytogenetic Map19q13.4UniSTS
Cytogenetic Map1p35-p34.3UniSTS
Cytogenetic Map7p11.2UniSTS
Cytogenetic Map5q35.1UniSTS
Cytogenetic Map12p13.3UniSTS
Cytogenetic Map2q14.3UniSTS
Cytogenetic Map5q31UniSTS
Cytogenetic Map11q13.5UniSTS
Cytogenetic Map13q14.3UniSTS
Cytogenetic Map7q32.1UniSTS
Cytogenetic Map14q32.31UniSTS
Cytogenetic Map12p13.1UniSTS
Cytogenetic Map14q32.12UniSTS
Cytogenetic Map6q22.31UniSTS
Cytogenetic Map3q27.1UniSTS
Cytogenetic Map1p34.1UniSTS
Cytogenetic Map11q13.1UniSTS
Cytogenetic Map10p14UniSTS
Cytogenetic MapXq13.2UniSTS
Cytogenetic Map9q21.13UniSTS
Cytogenetic Map8q21.11UniSTS
Cytogenetic Map4p16.1UniSTS
Cytogenetic Map3q13.13UniSTS
Cytogenetic Map3p21UniSTS
Cytogenetic Map2q35UniSTS
Cytogenetic Map1p36.33UniSTS
Cytogenetic Map18q12.1UniSTS
Cytogenetic Map14q11.2UniSTS
Cytogenetic Map5q31.3UniSTS
Cytogenetic MapXp11.22UniSTS
Cytogenetic Map12q24.31UniSTS
Cytogenetic Map12p12UniSTS
Cytogenetic Map11q24UniSTS
Cytogenetic Map6p21.1UniSTS
Cytogenetic Map7p15.3UniSTS
Cytogenetic Map14q31.1UniSTS
Cytogenetic Map15q22UniSTS
Cytogenetic Map1q31-q41UniSTS
Cytogenetic Map5q23.2UniSTS
Cytogenetic Map2q24.2UniSTS
Cytogenetic Map6q22-q23UniSTS
Cytogenetic Map1q24-q25.3UniSTS
Cytogenetic Map20q11.22-q11.23UniSTS
Cytogenetic Map8q24.22UniSTS
Cytogenetic Map17q25.1UniSTS
Cytogenetic Map1pter-q31.3UniSTS
Cytogenetic Map11q22-q23UniSTS
Cytogenetic Map12q24.2-q24.31UniSTS
Cytogenetic MapXq13.1UniSTS
Cytogenetic Map1q25UniSTS
Cytogenetic Map15q26.3UniSTS
Cytogenetic Map15q13.1UniSTS
Cytogenetic Map7q11.21UniSTS
Cytogenetic Map16p13UniSTS
Cytogenetic Map18q21UniSTS
Cytogenetic Map4p13UniSTS
Cytogenetic Map8q22.3UniSTS
Cytogenetic Map19p12UniSTS
Cytogenetic Map16p12.1UniSTS
Cytogenetic Map10p11.1UniSTS
Cytogenetic Map2q12.3UniSTS
Cytogenetic Map1p21.2UniSTS
Cytogenetic Map19q13.11UniSTS
Cytogenetic Map2q11.2-q12UniSTS
Cytogenetic MapXp22.12UniSTS
Cytogenetic Map20q11.23UniSTS
Cytogenetic Map19q13.31UniSTS
Cytogenetic Map13q32.2UniSTS
Cytogenetic Map3q25.33UniSTS
Cytogenetic Map1q32.1UniSTS
Cytogenetic Map10q25.3UniSTS
Cytogenetic Map15q14-q15UniSTS
Cytogenetic Map1p34UniSTS
Cytogenetic Map1q21UniSTS
Cytogenetic Map3p21.32UniSTS
Cytogenetic Map6q25.1UniSTS
Cytogenetic Map11p15.5UniSTS
Cytogenetic Map11q12.2UniSTS
Cytogenetic Map7p13-p12UniSTS
Cytogenetic Map1p36-p35UniSTS
Cytogenetic MapXq25UniSTS
Cytogenetic Map12q24.33UniSTS
Cytogenetic Map12q23UniSTS
Cytogenetic Map4q13UniSTS
Cytogenetic MapXq24UniSTS
Cytogenetic MapXq12UniSTS
Cytogenetic Map17q21.2UniSTS
Cytogenetic Map19p13.13UniSTS
Cytogenetic Map19q13.41UniSTS
Cytogenetic Map12q13.13UniSTS
Cytogenetic Map11q14.1UniSTS
Cytogenetic Map19q13.1UniSTS
Cytogenetic Map16q22.3UniSTS
Cytogenetic MapXq21.3UniSTS
Cytogenetic Map2p15-p13UniSTS
Cytogenetic Map3p14.1UniSTS
Cytogenetic Map1q25.2UniSTS
Cytogenetic Map2p12UniSTS
Cytogenetic Map6p12.3-p11.2UniSTS
Cytogenetic Map6q27UniSTS
Cytogenetic Map9q34UniSTS
Cytogenetic Map19q13.42UniSTS
Cytogenetic Map1q21.2UniSTS
Cytogenetic Map12q13.12UniSTS
Cytogenetic Map4p16UniSTS
Cytogenetic Map2p25.1-p24.1UniSTS
Cytogenetic Map7q34UniSTS
Cytogenetic Map5p13.1UniSTS
Cytogenetic Map22q11.1UniSTS
Cytogenetic Map5q13UniSTS
Cytogenetic Map15q22.31UniSTS
Cytogenetic MapXp22.11UniSTS
Cytogenetic Map12q24UniSTS
Cytogenetic Map1p21UniSTS
Cytogenetic Map16q24.1UniSTS
Cytogenetic Map5q34UniSTS
Cytogenetic Map6q21UniSTS
Cytogenetic Map10q24.32UniSTS
Cytogenetic Map7p13UniSTS
Cytogenetic Map7p22.1UniSTS
Cytogenetic Map18q21.1UniSTS
Cytogenetic Map3q29UniSTS
Cytogenetic Map16p13.2UniSTS
Cytogenetic Map17p12UniSTS
Cytogenetic Map16q23.1UniSTS
Cytogenetic Map9q22.1-q22.2UniSTS
Cytogenetic Map14q32UniSTS
Cytogenetic Map1p36.3-p36.2UniSTS
Cytogenetic Map4q28.1UniSTS
Cytogenetic Map12q13.1-q13.2UniSTS
Cytogenetic Map1p31UniSTS
Cytogenetic Map19q13.2UniSTS
Cytogenetic Map5p15.33UniSTS
Cytogenetic Map2q31.1UniSTS
Cytogenetic Map8p22UniSTS
Cytogenetic Map1p34.3UniSTS
Cytogenetic Map18q21.32UniSTS
Cytogenetic Map15q15.3UniSTS
Cytogenetic Map15q21.3UniSTS
Cytogenetic Map13q14.11UniSTS
Cytogenetic Map10q22.2UniSTS
Cytogenetic Map2q33.1UniSTS
Cytogenetic Map2q36.1UniSTS
Cytogenetic Map2q11.2UniSTS
Cytogenetic Map1q42.13UniSTS
Cytogenetic Map1q21.1UniSTS
Cytogenetic Map17q21.32UniSTS
Cytogenetic Map11q23.3UniSTS
Cytogenetic Map18q11.1UniSTS
Cytogenetic Map11q25UniSTS
Cytogenetic Map20q11.22UniSTS
Cytogenetic Map14q12UniSTS
Cytogenetic Map6pter-p12.1UniSTS
Cytogenetic Map13q12-q14UniSTS
Cytogenetic Map3p21.3UniSTS
Cytogenetic Map12qUniSTS
Cytogenetic Map5q13.1UniSTS
Cytogenetic Map7p22.3UniSTS
Cytogenetic Map16p12.2UniSTS
Cytogenetic Map13q34UniSTS
Cytogenetic Map17q23.2UniSTS
Cytogenetic Map3q25.1UniSTS
Cytogenetic Map14q31UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:4255
Count of miRNA genes:1069
Interacting mature miRNAs:1315
Transcripts:ENST00000332149, ENST00000398585, ENST00000424093, ENST00000454499, ENST00000455813, ENST00000458356, ENST00000463138, ENST00000469395, ENST00000488556, ENST00000489201, ENST00000497881
Prediction methods:Microtar, Miranda, Rnahybrid, Rnahybrid,Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High 10
Medium 867 3 755 418 130 266 359 6 1 230 360 1114 152 7 185 1 2
Low 446 38 657 181 80 173 1131 110 317 83 643 348 17 1 56 523 4
Below cutoff 1065 2438 288 23 1176 24 2345 1798 3031 78 416 128 3 923 1696 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_047085 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001135099 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001382720 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_005656 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA904080 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF123453 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF270487 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF318374 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF329454 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ276404 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK123948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK222784 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK291813 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK296860 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK313338 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL163285 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AP001610 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC015819 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC035623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC051839 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BP276431 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471079 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DC382934 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ204771 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KC877889 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U75329 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000332149   ⟹   ENSP00000330330
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl2141,464,305 - 41,508,158 (-)Ensembl
RefSeq Acc Id: ENST00000398585   ⟹   ENSP00000381588
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl2141,464,553 - 41,508,065 (-)Ensembl
RefSeq Acc Id: ENST00000424093   ⟹   ENSP00000397846
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl2141,466,142 - 41,508,092 (-)Ensembl
RefSeq Acc Id: ENST00000454499   ⟹   ENSP00000389006
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl2141,466,142 - 41,531,116 (-)Ensembl
RefSeq Acc Id: ENST00000455813   ⟹   ENSP00000391784
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl2141,494,356 - 41,506,604 (-)Ensembl
RefSeq Acc Id: ENST00000458356   ⟹   ENSP00000391216
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl2141,466,009 - 41,508,158 (-)Ensembl
RefSeq Acc Id: ENST00000463138
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl2141,488,489 - 41,508,114 (-)Ensembl
RefSeq Acc Id: ENST00000469395
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl2141,467,766 - 41,468,837 (-)Ensembl
RefSeq Acc Id: ENST00000488556
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl2141,465,890 - 41,468,102 (-)Ensembl
RefSeq Acc Id: ENST00000489201
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl2141,529,789 - 41,531,098 (-)Ensembl
RefSeq Acc Id: ENST00000676973   ⟹   ENSP00000504705
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl2141,464,305 - 41,507,700 (-)Ensembl
RefSeq Acc Id: ENST00000677680   ⟹   ENSP00000504526
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl2141,464,305 - 41,508,158 (-)Ensembl
RefSeq Acc Id: ENST00000678171   ⟹   ENSP00000503877
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl2141,464,305 - 41,508,158 (-)Ensembl
RefSeq Acc Id: ENST00000678348   ⟹   ENSP00000503556
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl2141,464,305 - 41,508,157 (-)Ensembl
RefSeq Acc Id: ENST00000678617
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl2141,466,142 - 41,498,189 (-)Ensembl
RefSeq Acc Id: ENST00000678743   ⟹   ENSP00000503377
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl2141,464,305 - 41,508,158 (-)Ensembl
RefSeq Acc Id: ENST00000678959   ⟹   ENSP00000503114
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl2141,464,305 - 41,508,158 (-)Ensembl
RefSeq Acc Id: ENST00000679016   ⟹   ENSP00000504610
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl2141,464,305 - 41,508,158 (-)Ensembl
RefSeq Acc Id: ENST00000679054   ⟹   ENSP00000502928
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl2141,464,305 - 41,508,146 (-)Ensembl
RefSeq Acc Id: ENST00000679181   ⟹   ENSP00000504238
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl2141,464,305 - 41,498,189 (-)Ensembl
RefSeq Acc Id: ENST00000679263   ⟹   ENSP00000504602
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl2141,464,300 - 41,512,108 (-)Ensembl
RefSeq Acc Id: NM_001135099   ⟹   NP_001128571
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382141,464,551 - 41,508,065 (-)NCBI
GRCh372142,836,236 - 42,880,085 (-)NCBI
HuRef2128,305,352 - 28,349,365 (-)ENTREZGENE
CHM1_12142,397,265 - 42,440,815 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001382720   ⟹   NP_001369649
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382141,464,551 - 41,508,158 (-)NCBI
RefSeq Acc Id: NM_005656   ⟹   NP_005647
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382141,464,305 - 41,508,158 (-)NCBI
GRCh372142,836,236 - 42,880,085 (-)NCBI
Build 362141,758,351 - 41,801,948 (-)NCBI Archive
HuRef2128,305,352 - 28,349,365 (-)ENTREZGENE
CHM1_12142,397,265 - 42,440,908 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_005647   ⟸   NM_005656
- Peptide Label: isoform 2
- UniProtKB: O15393 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001128571   ⟸   NM_001135099
- Peptide Label: isoform 1
- UniProtKB: O15393 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001369649   ⟸   NM_001382720
- Peptide Label: isoform 3
RefSeq Acc Id: ENSP00000381588   ⟸   ENST00000398585
RefSeq Acc Id: ENSP00000397846   ⟸   ENST00000424093
RefSeq Acc Id: ENSP00000330330   ⟸   ENST00000332149
RefSeq Acc Id: ENSP00000389006   ⟸   ENST00000454499
RefSeq Acc Id: ENSP00000391784   ⟸   ENST00000455813
RefSeq Acc Id: ENSP00000391216   ⟸   ENST00000458356
RefSeq Acc Id: ENSP00000504705   ⟸   ENST00000676973
RefSeq Acc Id: ENSP00000504526   ⟸   ENST00000677680
RefSeq Acc Id: ENSP00000503556   ⟸   ENST00000678348
RefSeq Acc Id: ENSP00000503877   ⟸   ENST00000678171
RefSeq Acc Id: ENSP00000503377   ⟸   ENST00000678743
RefSeq Acc Id: ENSP00000503114   ⟸   ENST00000678959
RefSeq Acc Id: ENSP00000504602   ⟸   ENST00000679263
RefSeq Acc Id: ENSP00000504238   ⟸   ENST00000679181
RefSeq Acc Id: ENSP00000504610   ⟸   ENST00000679016
RefSeq Acc Id: ENSP00000502928   ⟸   ENST00000679054
Protein Domains
LDL-receptor class A   Peptidase S1   SRCR

Promoters
RGD ID:13602892
Promoter ID:EPDNEW_H27631
Type:multiple initiation site
Name:TMPRSS2_1
Description:transmembrane protease, serine 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh382141,508,158 - 41,508,218EPDNEW

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46670405)x3 copy number gain See cases [RCV000050445] Chr21:7749532..46670405 [GRCh38]
Chr21:15499847..48090317 [GRCh37]
Chr21:14421718..46914745 [NCBI36]
Chr21:21p11.2-q22.3
pathogenic|conflicting interpretations of pathogenicity|conflicting data from submitters
GRCh38/hg38 21q22.3(chr21:41285201-46670405)x1 copy number loss See cases [RCV000051022] Chr21:41285201..46670405 [GRCh38]
Chr21:42657128..48090317 [GRCh37]
Chr21:41578998..46914745 [NCBI36]
Chr21:21q22.3
pathogenic
GRCh38/hg38 21q22.13-22.3(chr21:37135738-42434515)x1 copy number loss See cases [RCV000051047] Chr21:37135738..42434515 [GRCh38]
Chr21:38508038..43854625 [GRCh37]
Chr21:37429908..42727694 [NCBI36]
Chr21:21q22.13-22.3
pathogenic
GRCh37/hg19 21q22.1-22.3(chr21:35527952-44298520)x1 copy number loss See cases [RCV000052807] Chr21:35527952..44298520 [GRCh37]
Chr21:34449822..43171589 [NCBI36]
Chr21:21q22.1-22.3
pathogenic
GRCh38/hg38 21q22.12-22.3(chr21:35027972-46670405)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052836]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052836]|See cases [RCV000052836] Chr21:35027972..46670405 [GRCh38]
Chr21:36400269..48090317 [GRCh37]
Chr21:35322139..46914745 [NCBI36]
Chr21:21q22.12-22.3
pathogenic
GRCh38/hg38 21q22.13-22.3(chr21:38273492-46670405)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052838]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052838]|See cases [RCV000052838] Chr21:38273492..46670405 [GRCh38]
Chr21:39645414..48090317 [GRCh37]
Chr21:38567284..46914745 [NCBI36]
Chr21:21q22.13-22.3
pathogenic
GRCh38/hg38 21q22.2-22.3(chr21:40127825-46670546)x1 copy number loss See cases [RCV000052839] Chr21:40127825..46670546 [GRCh38]
Chr21:41499752..48090458 [GRCh37]
Chr21:40421622..46914886 [NCBI36]
Chr21:21q22.2-22.3
pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46623792)x3 copy number gain See cases [RCV000053042] Chr21:7749532..46623792 [GRCh38]
Chr21:14595524..48043704 [GRCh37]
Chr21:13517395..46868132 [NCBI36]
Chr21:21p11.2-q22.3
pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46623792)x3 copy number gain See cases [RCV000053043] Chr21:7749532..46623792 [GRCh38]
Chr21:14629063..48043704 [GRCh37]
Chr21:13550934..46868132 [NCBI36]
Chr21:21p11.2-q22.3
pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46670546)x3 copy number gain See cases [RCV000053045] Chr21:7749532..46670546 [GRCh38]
Chr21:15499647..48090458 [GRCh37]
Chr21:14421518..46914886 [NCBI36]
Chr21:21p11.2-q22.3
pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46661140)x3 copy number gain See cases [RCV000053065] Chr21:7749532..46661140 [GRCh38]
Chr21:15499647..48081052 [GRCh37]
Chr21:14421518..46905480 [NCBI36]
Chr21:21p11.2-q22.3
pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46661140)x3 copy number gain See cases [RCV000053067] Chr21:7749532..46661140 [GRCh38]
Chr21:15499847..48081052 [GRCh37]
Chr21:14421718..46905480 [NCBI36]
Chr21:21p11.2-q22.3
pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46670405)x3 copy number gain See cases [RCV000053068] Chr21:7749532..46670405 [GRCh38]
Chr21:20655360..48090317 [GRCh37]
Chr21:19577231..46914745 [NCBI36]
Chr21:21p11.2-q22.3
pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46670405)x3 copy number gain See cases [RCV000053069] Chr21:7749532..46670405 [GRCh38]
Chr21:34423268..48090317 [GRCh37]
Chr21:33345138..46914745 [NCBI36]
Chr21:21p11.2-q22.3
pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46623792)x3 copy number gain See cases [RCV000053039] Chr21:7749532..46623792 [GRCh38]
Chr21:14524963..48043704 [GRCh37]
Chr21:13446834..46868132 [NCBI36]
Chr21:21p11.2-q22.3
pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46653090)x3 copy number gain See cases [RCV000053040] Chr21:7749532..46653090 [GRCh38]
Chr21:14539679..48073002 [GRCh37]
Chr21:13461550..46897430 [NCBI36]
Chr21:21p11.2-q22.3
pathogenic
NM_005656.4(TMPRSS2):c.1222_1223del (p.Gln408fs) microsatellite Malignant tumor of prostate [RCV000149059] Chr21:41468487..41468488 [GRCh38]
Chr21:42840414..42840415 [GRCh37]
Chr21:21q22.3
uncertain significance
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-42971047)x3 copy number gain See cases [RCV000133676] Chr21:7749532..42971047 [GRCh38]
Chr21:15499847..44391157 [GRCh37]
Chr21:14421718..43264226 [NCBI36]
Chr21:21p11.2-q22.3
pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46653084)x3 copy number gain See cases [RCV000134727] Chr21:7749532..46653084 [GRCh38]
Chr21:15485038..48072996 [GRCh37]
Chr21:14406909..46897424 [NCBI36]
Chr21:21p11.2-q22.3
pathogenic
GRCh38/hg38 21q11.2-22.3(chr21:7749532-46649831)x3 copy number gain See cases [RCV000134509] Chr21:7749532..46649831 [GRCh38]
Chr21:14577835..48069743 [GRCh37]
Chr21:13499706..46894171 [NCBI36]
Chr21:21q11.2-22.3
pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46670440)x3 copy number gain See cases [RCV000134119] Chr21:7749532..46670440 [GRCh38]
Chr21:15485038..48090352 [GRCh37]
Chr21:14406909..46914780 [NCBI36]
Chr21:21p11.2-q22.3
pathogenic
GRCh38/hg38 21q22.11-22.3(chr21:7749532-46670346)x3 copy number gain See cases [RCV000135310] Chr21:7749532..46670346 [GRCh38]
Chr21:34111831..48090258 [GRCh37]
Chr21:33033702..46914686 [NCBI36]
Chr21:21q22.11-22.3
pathogenic
GRCh38/hg38 21q22.12-22.3(chr21:36206067-46670405)x3 copy number gain See cases [RCV000134972] Chr21:36206067..46670405 [GRCh38]
Chr21:37578365..48090317 [GRCh37]
Chr21:36500235..46914745 [NCBI36]
Chr21:21q22.12-22.3
pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46664250)x3 copy number gain See cases [RCV000134836] Chr21:7749532..46664250 [GRCh38]
Chr21:15485038..48084162 [GRCh37]
Chr21:14406909..46908590 [NCBI36]
Chr21:21p11.2-q22.3
pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46670440)x3 copy number gain See cases [RCV000134842] Chr21:7749532..46670440 [GRCh38]
Chr21:15513244..48090352 [GRCh37]
Chr21:14435115..46914780 [NCBI36]
Chr21:21p11.2-q22.3
pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46660999)x3 copy number gain See cases [RCV000135448] Chr21:7749532..46660999 [GRCh38]
Chr21:15499847..48080911 [GRCh37]
Chr21:14421718..46905339 [NCBI36]
Chr21:21p11.2-q22.3
pathogenic
GRCh38/hg38 21q22.13-22.3(chr21:36519173-46670405)x3 copy number gain See cases [RCV000136142] Chr21:36519173..46670405 [GRCh38]
Chr21:37891471..48090317 [GRCh37]
Chr21:36813341..46914745 [NCBI36]
Chr21:21q22.13-22.3
pathogenic
GRCh38/hg38 21q22.12-22.3(chr21:34789953-46636538)x1 copy number loss See cases [RCV000136828] Chr21:34789953..46636538 [GRCh38]
Chr21:36162250..48056450 [GRCh37]
Chr21:35084120..46880878 [NCBI36]
Chr21:21q22.12-22.3
pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46671060)x3 copy number gain See cases [RCV000137255] Chr21:7749532..46671060 [GRCh38]
Chr21:35319225..48090972 [GRCh37]
Chr21:34241095..46915400 [NCBI36]
Chr21:21p11.2-q22.3
pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46671060)x3 copy number gain See cases [RCV000137337] Chr21:7749532..46671060 [GRCh38]
Chr21:10697897..48090972 [GRCh37]
Chr21:1..46915400 [NCBI36]
Chr21:21p11.2-q22.3
pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46671060)x3 copy number gain See cases [RCV000138216] Chr21:7749532..46671060 [GRCh38]
Chr21:10944001..48090972 [GRCh37]
Chr21:9965872..46915400 [NCBI36]
Chr21:21p11.2-q22.3
pathogenic
GRCh38/hg38 21q22.13-22.3(chr21:37669628-46671060)x1 copy number loss See cases [RCV000138096] Chr21:37669628..46671060 [GRCh38]
Chr21:39041930..48090972 [GRCh37]
Chr21:37963800..46915400 [NCBI36]
Chr21:21q22.13-22.3
pathogenic
GRCh38/hg38 21q22.12-22.3(chr21:36066991-46671060)x3 copy number gain See cases [RCV000138164] Chr21:36066991..46671060 [GRCh38]
Chr21:37439289..48090972 [GRCh37]
Chr21:36361159..46915400 [NCBI36]
Chr21:21q22.12-22.3
pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46671060)x3 copy number gain See cases [RCV000138436] Chr21:7749532..46671060 [GRCh38]
Chr21:15451032..48090972 [GRCh37]
Chr21:14372903..46915400 [NCBI36]
Chr21:21p11.2-q22.3
pathogenic|conflicting data from submitters
GRCh38/hg38 21q22.2-22.3(chr21:40296025-46670440)x1 copy number loss See cases [RCV000139158] Chr21:40296025..46670440 [GRCh38]
Chr21:41667952..48090352 [GRCh37]
Chr21:40589822..46914780 [NCBI36]
Chr21:21q22.2-22.3
pathogenic
GRCh38/hg38 21q11.2-22.3(chr21:7749532-46670346)x3 copy number gain See cases [RCV000140103] Chr21:7749532..46670346 [GRCh38]
Chr21:14577894..48090258 [GRCh37]
Chr21:13499765..46914686 [NCBI36]
Chr21:21q11.2-22.3
pathogenic
GRCh38/hg38 21q11.2-22.3(chr21:7749532-46698247)x3 copy number gain See cases [RCV000141346] Chr21:7749532..46698247 [GRCh38]
Chr21:14577835..48118159 [GRCh37]
Chr21:13499706..46942587 [NCBI36]
Chr21:21q11.2-22.3
pathogenic
GRCh38/hg38 21q21.3-22.3(chr21:7749532-46677460)x3 copy number gain See cases [RCV000141827] Chr21:7749532..46677460 [GRCh38]
Chr21:28285299..48097372 [GRCh37]
Chr21:27207170..46921800 [NCBI36]
Chr21:21q21.3-22.3
uncertain significance
GRCh38/hg38 21q22.2-22.3(chr21:38816399-46677460)x1 copy number loss See cases [RCV000142311] Chr21:38816399..46677460 [GRCh38]
Chr21:40188323..48097372 [GRCh37]
Chr21:39110193..46921800 [NCBI36]
Chr21:21q22.2-22.3
pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7817158-46670440)x1 copy number loss See cases [RCV000142427] Chr21:7817158..46670440 [GRCh38]
Chr21:15485038..48090352 [GRCh37]
Chr21:14406909..46914780 [NCBI36]
Chr21:21p11.2-q22.3
pathogenic
GRCh38/hg38 21q22.2-22.3(chr21:39375937-44246148)x1 copy number loss See cases [RCV000142650] Chr21:39375937..44246148 [GRCh38]
Chr21:40747863..45666031 [GRCh37]
Chr21:39669733..44490459 [NCBI36]
Chr21:21q22.2-22.3
pathogenic
GRCh38/hg38 21q11.2-22.3(chr21:7749532-46677460)x3 copy number gain See cases [RCV000143376] Chr21:7749532..46677460 [GRCh38]
Chr21:15006458..48097372 [GRCh37]
Chr21:13928329..46921800 [NCBI36]
Chr21:21q11.2-22.3
pathogenic
GRCh38/hg38 21q22.3(chr21:41368412-42556043)x3 copy number gain See cases [RCV000143383] Chr21:41368412..42556043 [GRCh38]
Chr21:42740339..43976153 [GRCh37]
Chr21:41662209..42849222 [NCBI36]
Chr21:21q22.3
likely benign|uncertain significance
GRCh38/hg38 21q11.2-22.3(chr21:7749532-46677460) copy number gain See cases [RCV000143160] Chr21:7749532..46677460 [GRCh38]
Chr21:14386013..48097372 [GRCh37]
Chr21:13307884..46921800 [NCBI36]
Chr21:21q11.2-22.3
pathogenic
GRCh38/hg38 21q11.2-22.3(chr21:7749532-46677460)x3 copy number gain See cases [RCV000143120] Chr21:7749532..46677460 [GRCh38]
Chr21:15006457..48097372 [GRCh37]
Chr21:13928328..46921800 [NCBI36]
Chr21:21q11.2-22.3
pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46670405)x3 copy number gain See cases [RCV000148131] Chr21:7749532..46670405 [GRCh38]
Chr21:15499847..48090317 [GRCh37]
Chr21:14421718..46914745 [NCBI36]
Chr21:21p11.2-q22.3
pathogenic
GRCh37/hg19 21q11.2-22.3(chr21:15538655-48080926)x1 copy number loss See cases [RCV000239948] Chr21:15538655..48080926 [GRCh37]
Chr21:21q11.2-22.3
pathogenic
GRCh37/hg19 21q22.2-22.3(chr21:39841248-44652723)x3 copy number gain See cases [RCV000239953] Chr21:39841248..44652723 [GRCh37]
Chr21:21q22.2-22.3
pathogenic
NM_005656.4(TMPRSS2):c.1467G>A (p.Arg489=) single nucleotide variant not provided [RCV000487647] Chr21:41467734 [GRCh38]
Chr21:42839661 [GRCh37]
Chr21:21q22.3
uncertain significance
GRCh37/hg19 21q11.2-22.3(chr21:15410701-48090317)x3 copy number gain See cases [RCV000240397] Chr21:15410701..48090317 [GRCh37]
Chr21:21q11.2-22.3
pathogenic
GRCh37/hg19 21q11.2-22.3(chr21:15006457-43598570)x3 copy number gain See cases [RCV000446716] Chr21:15006457..43598570 [GRCh37]
Chr21:21q11.2-22.3
pathogenic
GRCh37/hg19 21q22.13-22.3(chr21:38790552-43619940)x1 copy number loss See cases [RCV000446516] Chr21:38790552..43619940 [GRCh37]
Chr21:21q22.13-22.3
pathogenic
GRCh37/hg19 21q22.2-22.3(chr21:42410406-48097372)x1 copy number loss See cases [RCV000448694] Chr21:42410406..48097372 [GRCh37]
Chr21:21q22.2-22.3
pathogenic
GRCh37/hg19 21q11.2-22.3(chr21:14771770-48080867)x3 copy number gain See cases [RCV000447884] Chr21:14771770..48080867 [GRCh37]
Chr21:21q11.2-22.3
pathogenic
GRCh37/hg19 21q11.2-22.3(chr21:15006457-44827632)x3 copy number gain See cases [RCV000448199] Chr21:15006457..44827632 [GRCh37]
Chr21:21q11.2-22.3
pathogenic
GRCh37/hg19 21q11.2-22.3(chr21:15285841-48097372)x3 copy number gain See cases [RCV000447729] Chr21:15285841..48097372 [GRCh37]
Chr21:21q11.2-22.3
pathogenic
GRCh37/hg19 21q11.2-22.3(chr21:15006457-48097372)x3 copy number gain See cases [RCV000447749] Chr21:15006457..48097372 [GRCh37]
Chr21:21q11.2-22.3
pathogenic
GRCh37/hg19 21q22.13-22.3(chr21:38699545-48097372)x1 copy number loss See cases [RCV000510684] Chr21:38699545..48097372 [GRCh37]
Chr21:21q22.13-22.3
pathogenic
GRCh37/hg19 21q22.2-22.3(chr21:41254101-48097372)x1 copy number loss See cases [RCV000511808] Chr21:41254101..48097372 [GRCh37]
Chr21:21q22.2-22.3
pathogenic
GRCh37/hg19 21q11.2-22.3(chr21:15006458-48097372) copy number gain See cases [RCV000511589] Chr21:15006458..48097372 [GRCh37]
Chr21:21q11.2-22.3
pathogenic
GRCh37/hg19 21q22.3(chr21:42661850-43590844)x3 copy number gain See cases [RCV000511842] Chr21:42661850..43590844 [GRCh37]
Chr21:21q22.3
uncertain significance
GRCh37/hg19 21q22.13-22.3(chr21:37914123-48097372)x1 copy number loss See cases [RCV000510798] Chr21:37914123..48097372 [GRCh37]
Chr21:21q22.13-22.3
pathogenic
GRCh37/hg19 21q22.2-22.3(chr21:42335622-48097372)x1 copy number loss not provided [RCV000684165] Chr21:42335622..48097372 [GRCh37]
Chr21:21q22.2-22.3
pathogenic
GRCh37/hg19 21q22.3(chr21:42805420-43176065)x3 copy number gain not provided [RCV000684141] Chr21:42805420..43176065 [GRCh37]
Chr21:21q22.3
uncertain significance
NC_000021.9:g.(?_38981673)_(41568791_?)del deletion Autistic disorder of childhood onset [RCV000754228] Chr21:38981673..41568791 [GRCh38]
Chr21:21q22.2-22.3
likely pathogenic
GRCh37/hg19 21p11.2-q22.3(chr21:10824040-48090629)x3 copy number gain not provided [RCV000741418] Chr21:10824040..48090629 [GRCh37]
Chr21:21p11.2-q22.3
pathogenic
GRCh37/hg19 21p11.2-q22.3(chr21:10827533-48100155)x3 copy number gain not provided [RCV000741419] Chr21:10827533..48100155 [GRCh37]
Chr21:21p11.2-q22.3
pathogenic
GRCh37/hg19 21q22.2-22.3(chr21:40364245-44169928)x1 copy number loss not provided [RCV000741567] Chr21:40364245..44169928 [GRCh37]
Chr21:21q22.2-22.3
pathogenic
GRCh37/hg19 21q22.3(chr21:42843754-42847436)x4 copy number gain not provided [RCV000741581] Chr21:42843754..42847436 [GRCh37]
Chr21:21q22.3
benign
GRCh37/hg19 21q22.3(chr21:42846162-42847531)x3 copy number gain not provided [RCV000741582] Chr21:42846162..42847531 [GRCh37]
Chr21:21q22.3
benign
GRCh37/hg19 21q22.3(chr21:42846162-42847575)x3 copy number gain not provided [RCV000741583] Chr21:42846162..42847575 [GRCh37]
Chr21:21q22.3
benign
GRCh37/hg19 21q22.3(chr21:42846804-42847531)x4 copy number gain not provided [RCV000741584] Chr21:42846804..42847531 [GRCh37]
Chr21:21q22.3
benign
GRCh37/hg19 21p11.2-q22.3(chr21:10699330-48117896)x3 copy number gain not provided [RCV000741413] Chr21:10699330..48117896 [GRCh37]
Chr21:21p11.2-q22.3
pathogenic
GRCh37/hg19 21p11.2-q22.3(chr21:10704198-48117896)x3 copy number gain not provided [RCV000741415] Chr21:10704198..48117896 [GRCh37]
Chr21:21p11.2-q22.3
pathogenic
NM_005656.4(TMPRSS2):c.540C>T (p.Tyr180=) single nucleotide variant not provided [RCV000950494] Chr21:41480508 [GRCh38]
Chr21:42852435 [GRCh37]
Chr21:21q22.3
benign
NM_005656.4(TMPRSS2):c.53A>G (p.His18Arg) single nucleotide variant not provided [RCV000901923] Chr21:41494541 [GRCh38]
Chr21:42866468 [GRCh37]
Chr21:21q22.3
benign
NM_005656.4(TMPRSS2):c.792G>A (p.Pro264=) single nucleotide variant not provided [RCV000924584] Chr21:41473432 [GRCh38]
Chr21:42845359 [GRCh37]
Chr21:21q22.3
benign
GRCh37/hg19 21q22.2-22.3(chr21:41537095-46914745) copy number loss not provided [RCV000767626] Chr21:41537095..46914745 [GRCh37]
Chr21:21q22.2-22.3
pathogenic
NM_005656.4(TMPRSS2):c.224C>T (p.Thr75Ile) single nucleotide variant not provided [RCV000953399] Chr21:41494370 [GRCh38]
Chr21:42866297 [GRCh37]
Chr21:21q22.3
benign
NM_005656.4(TMPRSS2):c.133T>G (p.Tyr45Asp) single nucleotide variant not provided [RCV000922879] Chr21:41494461 [GRCh38]
Chr21:42866388 [GRCh37]
Chr21:21q22.3
benign
NM_005656.4(TMPRSS2):c.648C>T (p.Ala216=) single nucleotide variant not provided [RCV000974663] Chr21:41479207 [GRCh38]
Chr21:42851134 [GRCh37]
Chr21:21q22.3
benign
Single allele deletion Neurodevelopmental disorder [RCV000787405] Chr21:42300424..43682911 [GRCh37]
Chr21:21q22.2-22.3
uncertain significance
GRCh37/hg19 21q22.13-22.3(chr21:39410438-45171756)x1 copy number loss not provided [RCV001007132] Chr21:39410438..45171756 [GRCh37]
Chr21:21q22.13-22.3
pathogenic
GRCh37/hg19 21q11.2-22.3(chr21:15006457-48097372)x3 copy number gain not provided [RCV000846937] Chr21:15006457..48097372 [GRCh37]
Chr21:21q11.2-22.3
pathogenic
GRCh37/hg19 21q22.3(chr21:42714287-42943077)x1 copy number loss not provided [RCV000848855] Chr21:42714287..42943077 [GRCh37]
Chr21:21q22.3
uncertain significance
NM_005656.4(TMPRSS2):c.99C>T (p.Val33=) single nucleotide variant not provided [RCV000955591] Chr21:41494495 [GRCh38]
Chr21:42866422 [GRCh37]
Chr21:21q22.3
benign
GRCh37/hg19 21q22.2-22.3(chr21:42044877-48100155)x3 copy number gain See cases [RCV001007433] Chr21:42044877..48100155 [GRCh37]
Chr21:21q22.2-22.3
pathogenic
GRCh37/hg19 21q11.2-22.3(chr21:14629063-48090317)x3 copy number gain See cases [RCV001263025] Chr21:14629063..48090317 [GRCh37]
Chr21:21q11.2-22.3
pathogenic

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:11876 AgrOrtholog
COSMIC TMPRSS2 COSMIC
Ensembl Genes ENSG00000184012 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000330330 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000381588 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000389006 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSP00000391216 UniProtKB/Swiss-Prot
  ENSP00000391784 UniProtKB/TrEMBL
  ENSP00000397846 UniProtKB/TrEMBL
  ENSP00000502928 UniProtKB/Swiss-Prot
  ENSP00000503114 UniProtKB/TrEMBL
  ENSP00000503377 UniProtKB/TrEMBL
  ENSP00000503556 UniProtKB/Swiss-Prot
  ENSP00000503877 ENTREZGENE, UniProtKB/TrEMBL
  ENSP00000504238 UniProtKB/TrEMBL
  ENSP00000504526 UniProtKB/TrEMBL
  ENSP00000504602 UniProtKB/TrEMBL
  ENSP00000504610 UniProtKB/TrEMBL
  ENSP00000504705 UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000332149 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000398585 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000424093 UniProtKB/TrEMBL
  ENST00000454499 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENST00000455813 UniProtKB/TrEMBL
  ENST00000458356 UniProtKB/Swiss-Prot
  ENST00000676973 UniProtKB/Swiss-Prot
  ENST00000677680 UniProtKB/TrEMBL
  ENST00000678171 ENTREZGENE, UniProtKB/TrEMBL
  ENST00000678348 UniProtKB/Swiss-Prot
  ENST00000678743 UniProtKB/TrEMBL
  ENST00000678959 UniProtKB/TrEMBL
  ENST00000679016 UniProtKB/TrEMBL
  ENST00000679054 UniProtKB/Swiss-Prot
  ENST00000679181 UniProtKB/TrEMBL
  ENST00000679263 UniProtKB/TrEMBL
Gene3D-CATH 2.40.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.10.250.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  4.10.400.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000184012 GTEx
HGNC ID HGNC:11876 ENTREZGENE
Human Proteome Map TMPRSS2 Human Proteome Map
InterPro LDL_receptor-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LDLR_class-A_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LDrepeatLR_classA_rpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_S1_PA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_S1_PA_chymotrypsin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_S1A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SRCR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SRCR-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SRCR-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Trypsin_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRYPSIN_HIS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRYPSIN_SER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:7113 UniProtKB/Swiss-Prot
NCBI Gene 7113 ENTREZGENE
OMIM 602060 OMIM
Pfam SRCR_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Trypsin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA36577 PharmGKB
PRINTS CHYMOTRYPSIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE LDLRA_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LDLRA_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SRCR_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRYPSIN_DOM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRYPSIN_HIS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRYPSIN_SER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART LDLa UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00202 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tryp_SPc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF50494 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF56487 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF57424 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A7I2V3D1_HUMAN UniProtKB/TrEMBL
  A0A7I2V474_HUMAN UniProtKB/TrEMBL
  A0A7I2V509_HUMAN UniProtKB/TrEMBL
  A0A7I2V5F9_HUMAN UniProtKB/TrEMBL
  A0A7I2V5N2_HUMAN UniProtKB/TrEMBL
  A0A7I2V650_HUMAN UniProtKB/TrEMBL
  A0A7I2YQ98_HUMAN UniProtKB/TrEMBL
  C9J5Y1_HUMAN UniProtKB/TrEMBL
  C9JB05_HUMAN UniProtKB/TrEMBL
  C9JKZ3_HUMAN UniProtKB/TrEMBL
  O15393 ENTREZGENE
  Q96T73_HUMAN UniProtKB/TrEMBL
  TMPS2_HUMAN UniProtKB/Swiss-Prot
UniProt Secondary A8K6Z8 UniProtKB/Swiss-Prot
  B2R8E5 UniProtKB/Swiss-Prot
  B7Z459 UniProtKB/Swiss-Prot
  D3DSJ2 UniProtKB/Swiss-Prot
  F8WES1 UniProtKB/Swiss-Prot
  Q6GTK7 UniProtKB/Swiss-Prot
  Q9BXX1 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-01-23 TMPRSS2  transmembrane serine protease 2    transmembrane protease, serine 2  Symbol and/or name change 5135510 APPROVED
2011-08-16 TMPRSS2  transmembrane protease, serine 2  TMPRSS2  transmembrane protease, serine 2  Symbol and/or name change 5135510 APPROVED