Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (1->4)-beta-D-glucan | multiple interactions | ISO | Tmem74b (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of TMEM74B mRNA | CTD | PMID:36331819 | 6-propyl-2-thiouracil | increases expression | ISO | Tmem74b (Rattus norvegicus) | 6480464 | Propylthiouracil results in increased expression of TMEM74B mRNA | CTD | PMID:24780913 and PMID:25825206 | acrylamide | increases expression | ISO | Tmem74b (Rattus norvegicus) | 6480464 | Acrylamide results in increased expression of TMEM74B mRNA | CTD | PMID:28959563 | acrylamide | decreases expression | EXP | | 6480464 | Acrylamide results in decreased expression of TMEM74B mRNA | CTD | PMID:32763439 | aflatoxin B1 | decreases methylation | EXP | | 6480464 | Aflatoxin B1 results in decreased methylation of TMEM74B gene | CTD | PMID:27153756 | aristolochic acid A | decreases expression | EXP | | 6480464 | aristolochic acid I results in decreased expression of TMEM74B mRNA | CTD | PMID:33212167 | arsane | affects methylation | EXP | | 6480464 | Arsenic affects the methylation of TMEM74B gene | CTD | PMID:25304211 | arsenic atom | affects methylation | EXP | | 6480464 | Arsenic affects the methylation of TMEM74B gene | CTD | PMID:25304211 | benzo[a]pyrene | decreases methylation | EXP | | 6480464 | Benzo(a)pyrene results in decreased methylation of TMEM74B promoter | CTD | PMID:27901495 | bisphenol A | decreases expression | ISO | Tmem74b (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of TMEM74B mRNA | CTD | PMID:25181051 | bisphenol A | increases expression | ISO | Tmem74b (Mus musculus) | 6480464 | bisphenol A results in increased expression of TMEM74B mRNA | CTD | PMID:38074096 | bisphenol F | increases methylation | EXP | | 6480464 | bisphenol F results in increased methylation of TMEM74B gene | CTD | PMID:31601247 | chlorpyrifos | decreases expression | ISO | Tmem74b (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of TMEM74B mRNA | CTD | PMID:32715474 | cisplatin | multiple interactions | EXP | | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of TMEM74B mRNA | CTD | PMID:27392435 | copper(II) sulfate | decreases expression | EXP | | 6480464 | Copper Sulfate results in decreased expression of TMEM74B mRNA | CTD | PMID:19549813 | cyclosporin A | decreases expression | EXP | | 6480464 | Cyclosporine results in decreased expression of TMEM74B mRNA | CTD | PMID:25562108 and PMID:27989131 | dioxygen | multiple interactions | EXP | | 6480464 | 1-cyclopropyl-4-(4-((5-methyl-3-(3-(4-(trifluoromethoxy)phenyl)-1 more ... | CTD | PMID:24403227 | dioxygen | increases expression | EXP | | 6480464 | Oxygen deficiency results in increased expression of TMEM74B mRNA | CTD | PMID:24403227 and PMID:26516004 | dorsomorphin | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TMEM74B mRNA | CTD | PMID:27188386 | entinostat | increases expression | EXP | | 6480464 | entinostat results in increased expression of TMEM74B mRNA | CTD | PMID:27188386 | ketamine | decreases expression | ISO | Tmem74b (Rattus norvegicus) | 6480464 | Ketamine results in decreased expression of TMEM74B mRNA | CTD | PMID:20080153 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of TMEM74B mRNA | CTD | PMID:29067470 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Tmem74b (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of TMEM74B mRNA | CTD | PMID:36331819 | resveratrol | multiple interactions | EXP | | 6480464 | [Plant Extracts co-treated with Resveratrol] results in decreased expression of TMEM74B mRNA | CTD | PMID:23557933 | SB 431542 | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TMEM74B mRNA | CTD | PMID:27188386 | silicon dioxide | decreases expression | EXP | | 6480464 | Silicon Dioxide analog results in decreased expression of TMEM74B mRNA | CTD | PMID:25895662 | sodium arsenite | increases expression | ISO | Tmem74b (Mus musculus) | 6480464 | sodium arsenite results in increased expression of TMEM74B mRNA | CTD | PMID:37682722 | sunitinib | decreases expression | EXP | | 6480464 | Sunitinib results in decreased expression of TMEM74B mRNA | CTD | PMID:31533062 | thimerosal | decreases expression | EXP | | 6480464 | Thimerosal results in decreased expression of TMEM74B mRNA | CTD | PMID:27188386 | titanium dioxide | decreases expression | ISO | Tmem74b (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of TMEM74B mRNA | CTD | PMID:29264374 | trichloroethene | increases expression | ISO | Tmem74b (Rattus norvegicus) | 6480464 | Trichloroethylene results in increased expression of TMEM74B mRNA | CTD | PMID:33387578 | urethane | decreases expression | EXP | | 6480464 | Urethane results in decreased expression of TMEM74B mRNA | CTD | PMID:28818685 | valproic acid | affects expression | EXP | | 6480464 | Valproic Acid affects the expression of TMEM74B mRNA | CTD | PMID:25979313 | valproic acid | increases expression | EXP | | 6480464 | Valproic Acid results in increased expression of TMEM74B mRNA | CTD | PMID:26272509 | valproic acid | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TMEM74B mRNA | CTD | PMID:27188386 | zoledronic acid | increases expression | EXP | | 6480464 | zoledronic acid results in increased expression of TMEM74B mRNA | CTD | PMID:24714768 | |