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Gene: ICOSLG (inducible T cell costimulator ligand) Homo sapiens
Symbol: ICOSLG
Name: inducible T cell costimulator ligand
RGD ID: 1354040
Description: Exhibits identical protein binding activity. Predicted to be involved in T cell receptor signaling pathway and positive regulation of interleukin-4 production. Localizes to cytoplasmic ribonucleoprotein granule and plasma membrane; INTERACTS WITH (-)-epigallocatechin 3-gallate; 2,3,7,8-tetrachlorodibenzodioxine; 3-isobutyl-1-methyl-7H-xanthine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: B7 homolog 2; B7 homologue 2; B7-H2; B7-like protein Gl50; B7-related protein 1; B7h; B7H2; B7RP-1; B7RP1; CD275; GL50; ICOS ligand; ICOS-L; ICOSL; inducible T-cell co-stimulator ligand; inducible T-cell costimulator ligand; KIAA0653; LICOS; transmembrane protein B7-H2 ICOS ligand
Mus musculus (house mouse) : Icosl (icos ligand)  MGI  Alliance
Rattus norvegicus (Norway rat) : Icoslg (inducible T-cell co-stimulator ligand)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Icoslg (inducible T cell costimulator ligand)
Pan paniscus (bonobo/pygmy chimpanzee) : ICOSLG (inducible T cell costimulator ligand)
Canis lupus familiaris (dog) : ICOSLG (inducible T cell costimulator ligand)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Icoslg (inducible T cell costimulator ligand)
Sus scrofa (pig) : ICOSLG (inducible T cell costimulator ligand)
Chlorocebus sabaeus (African green monkey) : ICOSLG (inducible T cell costimulator ligand)
Heterocephalus glaber (naked mole-rat) : Icoslg (inducible T cell costimulator ligand)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl2144,217,014 - 44,240,966 (-)EnsemblGRCh38hg38GRCh38
GRCh382144,216,979 - 44,240,943 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372145,642,874 - 45,660,881 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362144,471,149 - 44,485,262 (-)NCBINCBI36hg18NCBI36
Build 342144,471,151 - 44,485,262NCBI
Celera2130,751,996 - 30,766,092 (-)NCBI
Cytogenetic Map21q22.3NCBI
HuRef2131,016,759 - 31,030,941 (-)NCBIHuRef
CHM1_12145,203,515 - 45,221,529 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on ICOSLG
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1354040
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-09-29
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.