Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: VSIG4 (V-set and immunoglobulin domain containing 4) Homo sapiens
Symbol: VSIG4
Name: V-set and immunoglobulin domain containing 4
Description: Exhibits complement component C3b binding activity. Involved in negative regulation of complement activation, alternative pathway. Localizes to the protein-containing complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: complement receptor of the immunoglobulin superfamily; CRIg; Ig superfamily protein; V-set and immunoglobulin domain-containing protein 4; Z39IG
Mus musculus (house mouse) : Vsig4 (V-set and immunoglobulin domain containing 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Vsig4 (V-set and immunoglobulin domain containing 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Vsig4 (V-set and immunoglobulin domain containing 4)
Pan paniscus (bonobo/pygmy chimpanzee) : VSIG4 (V-set and immunoglobulin domain containing 4)
Canis lupus familiaris (dog) : VSIG4 (V-set and immunoglobulin domain containing 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Vsig4 (V-set and immunoglobulin domain containing 4)
Sus scrofa (pig) : VSIG4 (V-set and immunoglobulin domain containing 4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 EnsemblX66,021,738 - 66,040,125 (-)Ensembl
GRCh38X66,021,738 - 66,040,125 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X65,241,580 - 65,259,967 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X65,158,305 - 65,176,692 (-)NCBINCBI36hg18NCBI36
Build 34X65,024,600 - 65,042,906NCBI
CeleraX65,588,725 - 65,607,111 (-)NCBI
Cytogenetic MapXq12NCBI
HuRefX59,068,686 - 59,087,663 (-)NCBIHuRef
CHM1_1X65,134,610 - 65,152,555 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on VSIG4
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1354021
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.