AK9 (adenylate kinase 9) - Rat Genome Database

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Gene: AK9 (adenylate kinase 9) Homo sapiens
Analyze
Symbol: AK9
Name: adenylate kinase 9
RGD ID: 1354002
HGNC Page HGNC
Description: Enables nucleoside diphosphate kinase activity and nucleoside monophosphate kinase activity. Involved in nucleotide metabolic process. Located in cytoplasm; nuclear membrane; and nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: adenylate kinase domain containing 1; adenylate kinase domain containing 2; AK 9; AKD1; AKD2; C6orf199; C6orf224; chromosome 6 open reading frame 224; dJ70A9.1; FLJ34784; FLJ42177; MGC26954; RP1-70A9.1
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl6109,492,855 - 109,691,217 (-)EnsemblGRCh38hg38GRCh38
GRCh386109,492,855 - 109,691,202 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh376109,814,058 - 110,012,405 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366110,059,592 - 110,119,113 (-)NCBINCBI36hg18NCBI36
Build 346110,059,591 - 110,119,113NCBI
Celera6110,560,655 - 110,759,036 (-)NCBI
Cytogenetic Map6q21NCBI
HuRef6107,380,087 - 107,578,597 (-)NCBIHuRef
CHM1_16110,077,000 - 110,275,395 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,IDA)
cytosol  (TAS)
mitochondrion  (IBA)
nuclear membrane  (IDA)
nucleoplasm  (IDA)
nucleus  (IDA)

Molecular Function

References

Additional References at PubMed
PMID:10215863   PMID:11181995   PMID:12477932   PMID:14574404   PMID:14702039   PMID:15489334   PMID:16169070   PMID:16344560   PMID:19684573   PMID:20379614   PMID:20602751   PMID:21145461  
PMID:21873635   PMID:23416111   PMID:26344197   PMID:27966543   PMID:28514442   PMID:31560077   PMID:31586073   PMID:33961781  


Genomics

Comparative Map Data
AK9
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl6109,492,855 - 109,691,217 (-)EnsemblGRCh38hg38GRCh38
GRCh386109,492,855 - 109,691,202 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh376109,814,058 - 110,012,405 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366110,059,592 - 110,119,113 (-)NCBINCBI36hg18NCBI36
Build 346110,059,591 - 110,119,113NCBI
Celera6110,560,655 - 110,759,036 (-)NCBI
Cytogenetic Map6q21NCBI
HuRef6107,380,087 - 107,578,597 (-)NCBIHuRef
CHM1_16110,077,000 - 110,275,395 (-)NCBICHM1_1
Ak9
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391041,179,433 - 41,309,565 (+)NCBIGRCm39mm39
GRCm39 Ensembl1041,179,976 - 41,310,530 (+)Ensembl
GRCm381041,303,432 - 41,433,569 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1041,303,980 - 41,434,534 (+)EnsemblGRCm38mm10GRCm38
MGSCv371041,036,053 - 41,153,094 (+)NCBIGRCm37mm9NCBIm37
MGSCv361041,044,897 - 41,170,476 (+)NCBImm8
Celera1042,210,788 - 42,327,936 (+)NCBICelera
Cytogenetic Map10B1NCBI
Ak9
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22044,724,494 - 44,941,135 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl2044,724,496 - 44,941,136 (+)Ensembl
Rnor_6.02046,044,901 - 46,162,015 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2046,044,892 - 46,162,073 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02047,786,342 - 47,859,461 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42045,274,347 - 45,403,396 (+)NCBIRGSC3.4rn4RGSC3.4
Celera2055,011,652 - 55,087,256 (-)NCBICelera
Celera2045,523,222 - 45,559,777 (+)NCBICelera
Cytogenetic Map20q12NCBI
Ak9
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955402665 - 124,777 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955402704 - 128,521 (-)NCBIChiLan1.0ChiLan1.0
AK9
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.16111,344,563 - 111,539,932 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6111,344,834 - 111,539,932 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v06107,296,088 - 107,495,623 (-)NCBIMhudiblu_PPA_v0panPan3
AK9
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11266,381,215 - 66,508,559 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1266,389,190 - 66,500,273 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1266,200,889 - 66,328,259 (-)NCBI
ROS_Cfam_1.01267,273,574 - 67,393,506 (-)NCBI
UMICH_Zoey_3.11266,621,642 - 66,741,395 (-)NCBI
UNSW_CanFamBas_1.01266,462,926 - 66,590,946 (-)NCBI
UU_Cfam_GSD_1.01266,734,701 - 66,862,137 (-)NCBI
Ak9
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946101,335,164 - 101,461,240 (-)NCBI
SpeTri2.0NW_0049365645,610,445 - 5,727,782 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AK9
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1175,558,009 - 75,693,415 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2184,916,875 - 84,967,083 (+)NCBISscrofa10.2Sscrofa10.2susScr3
AK9
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11364,187,376 - 64,379,458 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1364,196,413 - 64,379,460 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604036,489,415 - 36,666,478 (+)NCBIVero_WHO_p1.0
Ak9
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462480530,647 - 163,314 (-)NCBIHetGla_female_1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:498
Count of miRNA genes:380
Interacting mature miRNAs:413
Transcripts:ENST00000285397, ENST00000341338, ENST00000355283, ENST00000368948, ENST00000424296, ENST00000448084, ENST00000466992, ENST00000470564, ENST00000490722, ENST00000491875, ENST00000524674, ENST00000532976, ENST00000605986
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component
High
Medium 2 38 4 227 20
Low 2424 2409 1563 484 1457 327 4285 2025 3618 404 1207 1579 171 1 1201 2737 3
Below cutoff 12 577 161 138 453 138 70 169 109 15 23 13 2 3 51 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001145128 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001329602 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001329603 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_145025 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_138057 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006715376 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011535550 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011535552 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011535553 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011535554 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011535555 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011535556 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011535558 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011535559 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017010384 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017010385 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017010386 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017010387 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017010388 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017010389 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024446350 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_942337 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AK055538 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK098657 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK124171 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK131244 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK315561 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL109947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL121788 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL133472 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL139391 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL832162 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC022031 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC087860 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC101714 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC111948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC143533 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471051 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA106296 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DW009925 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000285397   ⟹   ENSP00000285397
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl6109,631,693 - 109,691,217 (-)Ensembl
RefSeq Acc Id: ENST00000355283   ⟹   ENSP00000347431
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl6109,527,629 - 109,550,537 (-)Ensembl
RefSeq Acc Id: ENST00000368948   ⟹   ENSP00000357944
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl6109,579,345 - 109,691,217 (-)Ensembl
RefSeq Acc Id: ENST00000424296   ⟹   ENSP00000410186
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl6109,492,855 - 109,691,202 (-)Ensembl
RefSeq Acc Id: ENST00000448084   ⟹   ENSP00000407510
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl6109,641,538 - 109,690,506 (-)Ensembl
RefSeq Acc Id: ENST00000466992
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl6109,549,684 - 109,619,201 (-)Ensembl
RefSeq Acc Id: ENST00000470564   ⟹   ENSP00000418771
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl6109,492,859 - 109,533,333 (-)Ensembl
RefSeq Acc Id: ENST00000490722   ⟹   ENSP00000419758
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl6109,493,274 - 109,506,418 (-)Ensembl
RefSeq Acc Id: ENST00000491875   ⟹   ENSP00000418670
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl6109,527,628 - 109,545,895 (-)Ensembl
RefSeq Acc Id: ENST00000524674   ⟹   ENSP00000431394
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl6109,633,244 - 109,662,657 (-)Ensembl
RefSeq Acc Id: ENST00000532976   ⟹   ENSP00000436325
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl6109,644,670 - 109,690,670 (-)Ensembl
RefSeq Acc Id: ENST00000605986   ⟹   ENSP00000475585
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl6109,644,505 - 109,659,325 (-)Ensembl
RefSeq Acc Id: NM_001145128   ⟹   NP_001138600
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386109,492,855 - 109,691,202 (-)NCBI
HuRef6107,380,087 - 107,578,597 (-)NCBI
CHM1_16110,077,000 - 110,275,395 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001329602   ⟹   NP_001316531
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386109,631,696 - 109,691,202 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001329603   ⟹   NP_001316532
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386109,631,696 - 109,691,202 (-)NCBI
Sequence:
RefSeq Acc Id: NM_145025   ⟹   NP_659462
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386109,631,696 - 109,691,202 (-)NCBI
Build 366110,059,592 - 110,119,113 (-)NCBI Archive
HuRef6107,380,087 - 107,578,597 (-)NCBI
CHM1_16110,215,873 - 110,275,395 (-)NCBI
Sequence:
RefSeq Acc Id: NR_138057
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386109,631,696 - 109,691,202 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006715376   ⟹   XP_006715439
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386109,492,855 - 109,691,185 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011535550   ⟹   XP_011533852
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386109,492,855 - 109,691,185 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011535552   ⟹   XP_011533854
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386109,492,855 - 109,691,202 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011535553   ⟹   XP_011533855
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386109,492,855 - 109,690,670 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011535554   ⟹   XP_011533856
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386109,492,855 - 109,691,185 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011535555   ⟹   XP_011533857
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386109,506,817 - 109,691,185 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011535556   ⟹   XP_011533858
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386109,509,250 - 109,691,184 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011535558   ⟹   XP_011533860
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386109,492,855 - 109,583,249 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011535559   ⟹   XP_011533861
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386109,546,552 - 109,691,184 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017010384   ⟹   XP_016865873
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386109,504,802 - 109,691,185 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017010385   ⟹   XP_016865874
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386109,492,855 - 109,691,202 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017010386   ⟹   XP_016865875
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386109,504,802 - 109,691,185 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017010387   ⟹   XP_016865876
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386109,492,855 - 109,691,171 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017010388   ⟹   XP_016865877
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386109,527,628 - 109,691,184 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017010389   ⟹   XP_016865878
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386109,492,855 - 109,612,833 (-)NCBI
Sequence:
RefSeq Acc Id: XM_024446350   ⟹   XP_024302118
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386109,492,855 - 109,690,451 (-)NCBI
Sequence:
RefSeq Acc Id: XR_942337
RefSeq Status:
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386109,499,156 - 109,691,185 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001138600 (Get FASTA)   NCBI Sequence Viewer  
  NP_001316531 (Get FASTA)   NCBI Sequence Viewer  
  NP_001316532 (Get FASTA)   NCBI Sequence Viewer  
  NP_659462 (Get FASTA)   NCBI Sequence Viewer  
  XP_006715439 (Get FASTA)   NCBI Sequence Viewer  
  XP_011533852 (Get FASTA)   NCBI Sequence Viewer  
  XP_011533854 (Get FASTA)   NCBI Sequence Viewer  
  XP_011533855 (Get FASTA)   NCBI Sequence Viewer  
  XP_011533856 (Get FASTA)   NCBI Sequence Viewer  
  XP_011533857 (Get FASTA)   NCBI Sequence Viewer  
  XP_011533858 (Get FASTA)   NCBI Sequence Viewer  
  XP_011533860 (Get FASTA)   NCBI Sequence Viewer  
  XP_011533861 (Get FASTA)   NCBI Sequence Viewer  
  XP_016865873 (Get FASTA)   NCBI Sequence Viewer  
  XP_016865874 (Get FASTA)   NCBI Sequence Viewer  
  XP_016865875 (Get FASTA)   NCBI Sequence Viewer  
  XP_016865876 (Get FASTA)   NCBI Sequence Viewer  
  XP_016865877 (Get FASTA)   NCBI Sequence Viewer  
  XP_016865878 (Get FASTA)   NCBI Sequence Viewer  
  XP_024302118 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH22031 (Get FASTA)   NCBI Sequence Viewer  
  AAH87860 (Get FASTA)   NCBI Sequence Viewer  
  AAI01715 (Get FASTA)   NCBI Sequence Viewer  
  AAI11949 (Get FASTA)   NCBI Sequence Viewer  
  AAI43534 (Get FASTA)   NCBI Sequence Viewer  
  BAB70945 (Get FASTA)   NCBI Sequence Viewer  
  BAC05368 (Get FASTA)   NCBI Sequence Viewer  
  BAD18424 (Get FASTA)   NCBI Sequence Viewer  
  BAG37937 (Get FASTA)   NCBI Sequence Viewer  
  EAW48333 (Get FASTA)   NCBI Sequence Viewer  
  EAW48334 (Get FASTA)   NCBI Sequence Viewer  
  EAW48335 (Get FASTA)   NCBI Sequence Viewer  
  EAW48336 (Get FASTA)   NCBI Sequence Viewer  
  Q5TCS8 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_659462   ⟸   NM_145025
- Peptide Label: isoform 2
- UniProtKB: Q5TCS8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001138600   ⟸   NM_001145128
- Peptide Label: isoform 1
- UniProtKB: Q5TCS8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006715439   ⟸   XM_006715376
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_011533854   ⟸   XM_011535552
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_011533856   ⟸   XM_011535554
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_011533852   ⟸   XM_011535550
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_011533855   ⟸   XM_011535553
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_011533860   ⟸   XM_011535558
- Peptide Label: isoform X13
- Sequence:
RefSeq Acc Id: XP_011533857   ⟸   XM_011535555
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_011533858   ⟸   XM_011535556
- Peptide Label: isoform X10
- Sequence:
RefSeq Acc Id: XP_011533861   ⟸   XM_011535559
- Peptide Label: isoform X14
- Sequence:
RefSeq Acc Id: XP_016865874   ⟸   XM_017010385
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_016865876   ⟸   XM_017010387
- Peptide Label: isoform X9
- Sequence:
RefSeq Acc Id: XP_016865878   ⟸   XM_017010389
- Peptide Label: isoform X12
- Sequence:
RefSeq Acc Id: XP_016865875   ⟸   XM_017010386
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_016865873   ⟸   XM_017010384
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_016865877   ⟸   XM_017010388
- Peptide Label: isoform X11
- Sequence:
RefSeq Acc Id: XP_024302118   ⟸   XM_024446350
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: NP_001316531   ⟸   NM_001329602
- Peptide Label: isoform 2
- UniProtKB: Q5TCS8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001316532   ⟸   NM_001329603
- Peptide Label: isoform 3
- Sequence:
RefSeq Acc Id: ENSP00000410186   ⟸   ENST00000424296
RefSeq Acc Id: ENSP00000419758   ⟸   ENST00000490722
RefSeq Acc Id: ENSP00000418670   ⟸   ENST00000491875
RefSeq Acc Id: ENSP00000436325   ⟸   ENST00000532976
RefSeq Acc Id: ENSP00000285397   ⟸   ENST00000285397
RefSeq Acc Id: ENSP00000418771   ⟸   ENST00000470564
RefSeq Acc Id: ENSP00000431394   ⟸   ENST00000524674
RefSeq Acc Id: ENSP00000357944   ⟸   ENST00000368948
RefSeq Acc Id: ENSP00000347431   ⟸   ENST00000355283
RefSeq Acc Id: ENSP00000407510   ⟸   ENST00000448084
RefSeq Acc Id: ENSP00000475585   ⟸   ENST00000605986

Promoters
RGD ID:7208873
Promoter ID:EPDNEW_H10181
Type:initiation region
Name:AK9_1
Description:adenylate kinase 9
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh386109,691,202 - 109,691,262EPDNEW
RGD ID:6804061
Promoter ID:HG_KWN:54615
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000285397,   ENST00000341338,   ENST00000368944,   ENST00000368948,   NM_001145128,   NM_014845,   OTTHUMT00000041767,   UC003PTS.1
Position:
Human AssemblyChrPosition (strand)Source
Build 366110,118,874 - 110,119,374 (+)MPROMDB

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 6q21-23.2(chr6:108944899-132067720)x1 copy number loss See cases [RCV000051196] Chr6:108944899..132067720 [GRCh38]
Chr6:109266102..132388860 [GRCh37]
Chr6:109372795..132430553 [NCBI36]
Chr6:6q21-23.2
pathogenic
NM_001145128.2(AK9):c.2929C>T (p.Pro977Ser) single nucleotide variant Malignant melanoma [RCV000067065] Chr6:109550125 [GRCh38]
Chr6:109871328 [GRCh37]
Chr6:109978021 [NCBI36]
Chr6:6q21
not provided
NM_001145128.2(AK9):c.5359C>T (p.Pro1787Ser) single nucleotide variant Malignant melanoma [RCV000061293] Chr6:109495397 [GRCh38]
Chr6:109816600 [GRCh37]
Chr6:109923293 [NCBI36]
Chr6:6q21
not provided
NM_001145128.2(AK9):c.2752-3323A>G single nucleotide variant Lung cancer [RCV000096426] Chr6:109553625 [GRCh38]
Chr6:109874828 [GRCh37]
Chr6:6q21
uncertain significance
GRCh38/hg38 6q16.3-21(chr6:102356502-111049879)x1 copy number loss See cases [RCV000134806] Chr6:102356502..111049879 [GRCh38]
Chr6:102804377..111371082 [GRCh37]
Chr6:102911070..111477775 [NCBI36]
Chr6:6q16.3-21
pathogenic
GRCh38/hg38 6q21(chr6:109612069-109749371)x1 copy number loss See cases [RCV000137397] Chr6:109612069..109749371 [GRCh38]
Chr6:109933272..110070574 [GRCh37]
Chr6:110039965..110177267 [NCBI36]
Chr6:6q21
likely pathogenic
GRCh38/hg38 6q21-22.1(chr6:107370141-115827482)x1 copy number loss See cases [RCV000138006] Chr6:107370141..115827482 [GRCh38]
Chr6:107691345..116148646 [GRCh37]
Chr6:107798038..116255339 [NCBI36]
Chr6:6q21-22.1
pathogenic
GRCh38/hg38 6q21(chr6:109563992-109661172)x1 copy number loss See cases [RCV000139790] Chr6:109563992..109661172 [GRCh38]
Chr6:109885195..109982375 [GRCh37]
Chr6:109991888..110089068 [NCBI36]
Chr6:6q21
uncertain significance
GRCh38/hg38 6q16.1-22.31(chr6:96609994-122161548)x1 copy number loss See cases [RCV000139465] Chr6:96609994..122161548 [GRCh38]
Chr6:97057870..122482694 [GRCh37]
Chr6:97164591..122524393 [NCBI36]
Chr6:6q16.1-22.31
pathogenic
GRCh38/hg38 6q13-24.1(chr6:74382807-142040500)x3 copy number gain See cases [RCV000139729] Chr6:74382807..142040500 [GRCh38]
Chr6:75092523..142361637 [GRCh37]
Chr6:75149243..142403330 [NCBI36]
Chr6:6q13-24.1
pathogenic
GRCh38/hg38 6q21(chr6:107445281-110547907)x1 copy number loss See cases [RCV000141382] Chr6:107445281..110547907 [GRCh38]
Chr6:107766485..110869110 [GRCh37]
Chr6:107873178..110975803 [NCBI36]
Chr6:6q21
pathogenic
GRCh38/hg38 6q21-22.31(chr6:106503719-125781219)x1 copy number loss See cases [RCV000141587] Chr6:106503719..125781219 [GRCh38]
Chr6:106951594..126102365 [GRCh37]
Chr6:107058287..126144058 [NCBI36]
Chr6:6q21-22.31
pathogenic
GRCh38/hg38 6q16.3-21(chr6:103279465-113934239)x1 copy number loss See cases [RCV000142287] Chr6:103279465..113934239 [GRCh38]
Chr6:103727340..114255403 [GRCh37]
Chr6:103834033..114362096 [NCBI36]
Chr6:6q16.3-21
pathogenic
GRCh38/hg38 6q16.3-22.31(chr6:100054889-120488154)x1 copy number loss See cases [RCV000143227] Chr6:100054889..120488154 [GRCh38]
Chr6:100502765..120809300 [GRCh37]
Chr6:100609486..120850999 [NCBI36]
Chr6:6q16.3-22.31
pathogenic
GRCh37/hg19 6q21(chr6:109564793-112223595)x1 copy number loss See cases [RCV000447293] Chr6:109564793..112223595 [GRCh37]
Chr6:6q21
uncertain significance
GRCh37/hg19 6q14.3-22.31(chr6:85988428-120548687)x1 copy number loss See cases [RCV000445666] Chr6:85988428..120548687 [GRCh37]
Chr6:6q14.3-22.31
pathogenic
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482)x3 copy number gain See cases [RCV000512067] Chr6:156975..170919482 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482) copy number gain See cases [RCV000510595] Chr6:156975..170919482 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6q16.1-21(chr6:97384446-110247755)x1 copy number loss See cases [RCV000510703] Chr6:97384446..110247755 [GRCh37]
Chr6:6q16.1-21
pathogenic
GRCh37/hg19 6q16.1-21(chr6:94202605-109878834)x1 copy number loss See cases [RCV000512470] Chr6:94202605..109878834 [GRCh37]
Chr6:6q16.1-21
pathogenic
GRCh37/hg19 6q16.1-22.1(chr6:95549951-116684929)x1 copy number loss not provided [RCV000682693] Chr6:95549951..116684929 [GRCh37]
Chr6:6q16.1-22.1
pathogenic
GRCh37/hg19 6p25.3-q27(chr6:108666-170980171)x3 copy number gain not provided [RCV000745403] Chr6:108666..170980171 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6p25.3-q27(chr6:60107-171054786)x3 copy number gain not provided [RCV000745400] Chr6:60107..171054786 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6p25.3-q27(chr6:165632-170919470)x3 copy number gain not provided [RCV000745404] Chr6:165632..170919470 [GRCh37]
Chr6:6p25.3-q27
pathogenic
NM_001145128.2(AK9):c.2192-9dup duplication not provided [RCV000963619] Chr6:109573596..109573597 [GRCh38]
Chr6:109894799..109894800 [GRCh37]
Chr6:6q21
benign
NM_001145128.2(AK9):c.1694-4T>C single nucleotide variant not provided [RCV000963620] Chr6:109610517 [GRCh38]
Chr6:109931720 [GRCh37]
Chr6:6q21
benign
NM_001145128.2(AK9):c.4896G>A (p.Leu1632=) single nucleotide variant not provided [RCV000972427] Chr6:109499194 [GRCh38]
Chr6:109820397 [GRCh37]
Chr6:6q21
benign
NM_001145128.3(AK9):c.1495+10T>C single nucleotide variant not provided [RCV000879154] Chr6:109614375 [GRCh38]
Chr6:109935578 [GRCh37]
Chr6:6q21
benign
NM_001145128.2(AK9):c.2280C>T (p.Thr760=) single nucleotide variant not provided [RCV000968098] Chr6:109573506 [GRCh38]
Chr6:109894709 [GRCh37]
Chr6:6q21
benign
NM_001145128.3(AK9):c.4773G>T (p.Trp1591Cys) single nucleotide variant not provided [RCV000949719] Chr6:109506403 [GRCh38]
Chr6:109827606 [GRCh37]
Chr6:6q21
benign
NM_001145128.3(AK9):c.4650T>C (p.Asn1550=) single nucleotide variant not provided [RCV000959621] Chr6:109506526 [GRCh38]
Chr6:109827729 [GRCh37]
Chr6:6q21
benign
GRCh37/hg19 6q21(chr6:109726649-110071067)x3 copy number gain not provided [RCV000846803] Chr6:109726649..110071067 [GRCh37]
Chr6:6q21
uncertain significance
NM_014845.5(FIG4):c.-365A>G single nucleotide variant not provided [RCV000826920] Chr6:109691071 [GRCh38]
Chr6:110012274 [GRCh37]
Chr6:6q21
likely benign
NM_001145128.3(AK9):c.962A>G (p.Tyr321Cys) single nucleotide variant not provided [RCV000959653] Chr6:109633295 [GRCh38]
Chr6:109954498 [GRCh37]
Chr6:6q21
benign
GRCh37/hg19 6q21(chr6:109721133-110193742)x3 copy number gain not provided [RCV000848987] Chr6:109721133..110193742 [GRCh37]
Chr6:6q21
uncertain significance
NM_001145128.3(AK9):c.1254+19G>A single nucleotide variant not provided [RCV001198626] Chr6:109632904 [GRCh38]
Chr6:109954107 [GRCh37]
Chr6:6q21
uncertain significance
NM_001145128.3(AK9):c.1254+12A>T single nucleotide variant not provided [RCV001198627] Chr6:109632911 [GRCh38]
Chr6:109954114 [GRCh37]
Chr6:6q21
uncertain significance
NM_001145128.3(AK9):c.1542C>G (p.Asp514Glu) single nucleotide variant not provided [RCV000959622] Chr6:109614250 [GRCh38]
Chr6:109935453 [GRCh37]
Chr6:6q21
benign
NM_001145128.3(AK9):c.1399+6A>G single nucleotide variant not provided [RCV000959623] Chr6:109619086 [GRCh38]
Chr6:109940289 [GRCh37]
Chr6:6q21
benign
NM_001145128.2(AK9):c.5277T>C (p.Tyr1759=) single nucleotide variant not provided [RCV000975122] Chr6:109497503 [GRCh38]
Chr6:109818706 [GRCh37]
Chr6:6q21
benign
NM_004837.4(GGPS1):c.782G>A (p.Arg261His) AND MUSCULAR DYSTROPHY, CONGENITAL HEARING LOSS, single nucleotide variant not provided [RCV001638986] Chr6:109564272 [GRCh38]
Chr6:109885475 [GRCh37]
Chr6:6q21
benign
GRCh37/hg19 6q21(chr6:109564694-112232351)x1 copy number loss not provided [RCV001007557] Chr6:109564694..112232351 [GRCh37]
Chr6:6q21
uncertain significance
GRCh37/hg19 6q21(chr6:109920344-110080533)x1 copy number loss not provided [RCV001005839] Chr6:109920344..110080533 [GRCh37]
Chr6:6q21
uncertain significance
GRCh37/hg19 6q16.3-22.1(chr6:101296547-117004249)x3 copy number gain Microcephaly [RCV001251053] Chr6:101296547..117004249 [GRCh37]
Chr6:6q16.3-22.1
pathogenic
GRCh37/hg19 6q16.1-21(chr6:98949950-114533905)x1 copy number loss Deletion 6q16 q21 [RCV001263224] Chr6:98949950..114533905 [GRCh37]
Chr6:6q16.1-21
pathogenic
GRCh37/hg19 6q21(chr6:109796301-113083437)x3 copy number gain See cases [RCV001353182] Chr6:109796301..113083437 [GRCh37]
Chr6:6q21
uncertain significance
NM_003895.3(SYNJ1):c.3486A>G (p.Pro1162=) single nucleotide variant not provided [RCV001688130] Chr6:109564802 [GRCh38]
Chr6:109886005 [GRCh37]
Chr6:6q21
benign

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:33814 AgrOrtholog
COSMIC AK9 COSMIC
Ensembl Genes ENSG00000155085 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000285397 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000347431 UniProtKB/Swiss-Prot
  ENSP00000357944 UniProtKB/TrEMBL
  ENSP00000407510 UniProtKB/TrEMBL
  ENSP00000410186 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000418670 UniProtKB/TrEMBL
  ENSP00000418771 UniProtKB/TrEMBL
  ENSP00000419758 UniProtKB/TrEMBL
  ENSP00000431394 UniProtKB/TrEMBL
  ENSP00000436325 UniProtKB/TrEMBL
  ENSP00000475585 UniProtKB/TrEMBL
Ensembl Transcript ENST00000285397 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000355283 UniProtKB/Swiss-Prot
  ENST00000368948 UniProtKB/TrEMBL
  ENST00000424296 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000448084 UniProtKB/TrEMBL
  ENST00000470564 UniProtKB/TrEMBL
  ENST00000490722 UniProtKB/TrEMBL
  ENST00000491875 UniProtKB/TrEMBL
  ENST00000524674 UniProtKB/TrEMBL
  ENST00000532976 UniProtKB/TrEMBL
  ENST00000605986 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000155085 GTEx
HGNC ID HGNC:33814 ENTREZGENE
Human Proteome Map AK9 Human Proteome Map
InterPro AAA+_ATPase UniProtKB/Swiss-Prot
  Adenylat/UMP-CMP_kin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:221264 UniProtKB/Swiss-Prot
NCBI Gene 221264 ENTREZGENE
OMIM 615358 OMIM
PANTHER PTHR23359 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA164715271 PharmGKB
SMART AAA UniProtKB/Swiss-Prot
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A075B7F5_HUMAN UniProtKB/TrEMBL
  B7ZL24_HUMAN UniProtKB/TrEMBL
  E9PPM3_HUMAN UniProtKB/TrEMBL
  E9PPU7_HUMAN UniProtKB/TrEMBL
  H0Y8C5_HUMAN UniProtKB/TrEMBL
  H0YCD1_HUMAN UniProtKB/TrEMBL
  H7C505_HUMAN UniProtKB/TrEMBL
  H7C517_HUMAN UniProtKB/TrEMBL
  J3KP89_HUMAN UniProtKB/TrEMBL
  KAD9_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary A6NL75 UniProtKB/Swiss-Prot
  B2RDJ0 UniProtKB/Swiss-Prot
  B6ZDM7 UniProtKB/Swiss-Prot
  Q3MIS4 UniProtKB/Swiss-Prot
  Q5I0W8 UniProtKB/Swiss-Prot
  Q6ZNF1 UniProtKB/Swiss-Prot
  Q6ZVR7 UniProtKB/Swiss-Prot
  Q8N7C6 UniProtKB/Swiss-Prot
  Q8WW00 UniProtKB/Swiss-Prot
  Q96NF4 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-04-05 AK9  adenylate kinase 9  AKD1  adenylate kinase domain containing 1  Data Merged 737654 PROVISIONAL
2016-03-25 AK9  adenylate kinase 9  C6orf224  chromosome 6 open reading frame 224  Data Merged 737654 PROVISIONAL
2014-09-08 AK9  adenylate kinase 9  AKD2  adenylate kinase domain containing 2  Symbol and/or name change 5135510 APPROVED