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Gene: CRY1 (cryptochrome circadian regulator 1) Homo sapiens
Symbol: CRY1
Name: cryptochrome circadian regulator 1
Description: Exhibits double-stranded DNA binding activity; nuclear hormone receptor binding activity; and phosphatase binding activity. Involved in negative regulation of transcription by RNA polymerase II. Localizes to the nucleus. Implicated in advanced sleep phase syndrome.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: cryptochrome 1 (photolyase-like); cryptochrome circadian clock 1; cryptochrome-1; DSPD; PHLL1; photolyase-like cryptochrome 1
Mus musculus (house mouse) : Cry1 (cryptochrome 1 (photolyase-like))  MGI  Alliance
Rattus norvegicus (Norway rat) : Cry1 (cryptochrome circadian regulator 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cry1 (cryptochrome circadian regulator 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CRY1 (cryptochrome circadian regulator 1)
Canis lupus familiaris (dog) : CRY1 (cryptochrome circadian regulator 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cry1 (cryptochrome circadian regulator 1)
Sus scrofa (pig) : CRY1 (cryptochrome circadian regulator 1)
Chlorocebus sabaeus (green monkey) : CRY1 (cryptochrome circadian regulator 1)
Heterocephalus glaber (naked mole-rat) : Cry1 (cryptochrome circadian regulator 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl12106,991,364 - 107,093,549 (-)Ensembl
GRCh3812106,991,364 - 107,093,872 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3712107,385,142 - 107,487,635 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612105,909,272 - 106,011,455 (-)NCBINCBI36hg18NCBI36
Build 3412105,887,608 - 105,989,792NCBI
Celera12107,050,701 - 107,153,165 (-)NCBI
Cytogenetic Map12q23.3NCBI
HuRef12104,445,641 - 104,548,152 (-)NCBIHuRef
CHM1_112107,350,774 - 107,453,198 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on CRY1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1353919
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.