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Gene: C3AR1 (complement C3a receptor 1) Homo sapiens
Symbol: C3AR1
Name: complement C3a receptor 1
RGD ID: 1353843
Description: Exhibits G protein-coupled receptor activity and complement component C3a receptor activity. Involved in complement receptor mediated signaling pathway and positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway. Predicted to localize to plasma membrane. Implicated in asthma. Biomarker of asthma and rhinitis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AZ3B; C3a anaphylatoxin chemotactic receptor; C3a-R; C3AR; complement component 3 receptor 1; complement component 3a receptor 1; HNFAG09
Mus musculus (house mouse) : C3ar1 (complement component 3a receptor 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : C3ar1 (complement C3a receptor 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : C3ar1 (complement C3a receptor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : C3AR1 (complement C3a receptor 1)
Canis lupus familiaris (dog) : C3AR1 (complement C3a receptor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : C3ar1 (complement C3a receptor 1)
Sus scrofa (pig) : C3AR1 (complement C3a receptor 1)
Chlorocebus sabaeus (African green monkey) : C3AR1 (complement C3a receptor 1)
Heterocephalus glaber (naked mole-rat) : C3ar1 (complement C3a receptor 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl128,056,844 - 8,066,359 (-)EnsemblGRCh38hg38GRCh38
GRCh38128,056,844 - 8,066,359 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37128,210,919 - 8,218,955 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36128,102,186 - 8,110,222 (-)NCBINCBI36hg18NCBI36
Build 34128,102,185 - 8,110,222NCBI
Celera129,787,991 - 9,796,026 (-)NCBI
Cytogenetic Map12p13.31NCBI
HuRef128,022,647 - 8,030,683 (-)NCBIHuRef
CHM1_1128,210,143 - 8,218,179 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on C3AR1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1353843
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-09-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.