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Gene: IGSF1 (immunoglobulin superfamily member 1) Homo sapiens
Symbol: IGSF1
Name: immunoglobulin superfamily member 1
Description: Exhibits activin receptor antagonist activity and inhibin binding activity. Involved in negative regulation of activin receptor signaling pathway and regulation of transcription, DNA-templated. Localizes to the membrane. Implicated in IGSF1 deficiency syndrome.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CHTE; IGCD1; IGDC1; immunoglobulin superfamily, member 1; immunoglobulin-like domain-containing protein 1; INHBP; inhibin-binding protein; KIAA0364; MGC75490; p120; PGSF2; pituitary gland-specific factor 2
Mus musculus (house mouse) : Igsf1 (immunoglobulin superfamily, member 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Igsf1 (immunoglobulin superfamily, member 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Igsf1 (immunoglobulin superfamily member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : IGSF1 (immunoglobulin superfamily member 1)
Canis lupus familiaris (dog) : IGSF1 (immunoglobulin superfamily member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Igsf1 (immunoglobulin superfamily member 1)
Sus scrofa (pig) : IGSF1 (immunoglobulin superfamily member 1)
Chlorocebus sabaeus (African green monkey) : IGSF1 (immunoglobulin superfamily member 1)
Heterocephalus glaber (naked mole-rat) : Igsf1 (immunoglobulin superfamily member 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 EnsemblX131,273,506 - 131,578,899 (-)Ensembl
GRCh38X131,273,506 - 131,289,457 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X130,407,480 - 130,423,403 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X130,235,161 - 130,250,936 (-)NCBINCBI36hg18NCBI36
Build 34X130,143,676 - 130,148,790NCBI
CeleraX130,793,906 - 130,809,827 (-)NCBI
Cytogenetic MapXq26.1NCBI
HuRefX119,813,192 - 119,829,114 (-)NCBIHuRef
CHM1_1X130,319,050 - 130,334,972 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on IGSF1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1353839
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-02-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.