SERPINA6 (serpin family A member 6) - Rat Genome Database

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Gene: SERPINA6 (serpin family A member 6) Homo sapiens
Analyze
Symbol: SERPINA6
Name: serpin family A member 6
RGD ID: 1353758
HGNC Page HGNC:1540
Description: Enables steroid binding activity. Predicted to act upstream of or within glucocorticoid metabolic process. Located in extracellular exosome. Implicated in corticosteroid-binding globulin deficiency.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: CBG; corticosteroid binding globulin; corticosteroid-binding globulin; serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6; serpin A6; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6; transcortin
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: SERPINA15P  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381494,304,248 - 94,323,336 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1494,304,248 - 94,323,389 (-)EnsemblGRCh38hg38GRCh38
GRCh371494,770,585 - 94,789,673 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361493,840,338 - 93,859,441 (-)NCBINCBI36Build 36hg18NCBI36
Build 341493,840,338 - 93,859,426NCBI
Celera1474,824,369 - 74,843,477 (-)NCBICelera
Cytogenetic Map14q32.13NCBI
HuRef1474,950,383 - 74,969,481 (-)NCBIHuRef
CHM1_11494,708,390 - 94,727,495 (-)NCBICHM1_1
T2T-CHM13v2.01488,531,534 - 88,550,620 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(1->4)-beta-D-glucan  (ISO)
(S)-colchicine  (ISO)
1,2-dichloroethane  (ISO)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,3-dimethoxynaphthalene-1,4-dione  (EXP)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
2-amino-4,6-dinitrotoluene  (ISO)
3,3',5-triiodo-L-thyronine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (EXP)
3H-1,2-dithiole-3-thione  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4-amino-2,6-dinitrotoluene  (ISO)
acetamide  (ISO)
aconitine  (ISO)
aflatoxin B1  (EXP,ISO)
aristolochic acid A  (EXP)
arsenous acid  (EXP)
benzo[a]pyrene  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
buspirone  (ISO)
buta-1,3-diene  (ISO)
cadmium atom  (EXP)
cadmium dichloride  (EXP)
caffeine  (EXP)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
clofibrate  (ISO)
cobalt dichloride  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (EXP)
cyclosporin A  (EXP)
cyproconazole  (ISO)
dexamethasone  (EXP,ISO)
diarsenic trioxide  (EXP)
drospirenone  (EXP)
epoxiconazole  (ISO)
ethanol  (ISO)
flutamide  (ISO)
fumonisin B1  (ISO)
glafenine  (ISO)
GW 4064  (ISO)
indometacin  (EXP)
lead(0)  (EXP)
leflunomide  (ISO)
lipopolysaccharide  (EXP)
methapyrilene  (ISO)
Mitotane  (EXP)
Monobutylphthalate  (ISO)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (EXP)
nefazodone  (ISO)
nickel atom  (EXP)
nimesulide  (ISO)
nitrofen  (ISO)
norgestimate  (EXP)
p-toluidine  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
pirinixic acid  (ISO)
potassium dichromate  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (EXP)
propiconazole  (ISO)
quercetin  (EXP)
resveratrol  (EXP,ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (EXP)
silicon dioxide  (EXP)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (EXP,ISO)
streptozocin  (ISO)
tetrachloromethane  (ISO)
Theaflavin 3,3'-digallate  (EXP)
thioacetamide  (EXP,ISO)
Triptolide  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)
withaferin A  (EXP)
zinc atom  (EXP)
zinc(0)  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. RGD HPO Phenotype Annotation Pipeline RGD automated import pipeline for human HPO-to-gene-to-disease annotations
Additional References at PubMed
PMID:932172   PMID:1504007   PMID:2240617   PMID:2253941   PMID:2608068   PMID:2612005   PMID:2821037   PMID:3299377   PMID:3347061   PMID:3386241   PMID:3751467   PMID:7172869  
PMID:7734053   PMID:7878688   PMID:7912884   PMID:8125298   PMID:8180202   PMID:8212073   PMID:8539782   PMID:9378466   PMID:9383284   PMID:9739422   PMID:10436419   PMID:10474016  
PMID:10634411   PMID:11076863   PMID:11161981   PMID:11502797   PMID:11752456   PMID:11893012   PMID:12154211   PMID:12364459   PMID:12477932   PMID:12554596   PMID:12780753   PMID:14760718  
PMID:14871264   PMID:15014966   PMID:15489334   PMID:15489336   PMID:15554358   PMID:15877287   PMID:16222046   PMID:16335952   PMID:16381901   PMID:16502470   PMID:17245537   PMID:17547679  
PMID:18513745   PMID:18636124   PMID:19011238   PMID:19086053   PMID:19172388   PMID:19336370   PMID:19723618   PMID:19913121   PMID:20226861   PMID:20354921   PMID:20379614   PMID:20403506  
PMID:20628086   PMID:20716560   PMID:20839151   PMID:21325280   PMID:21558494   PMID:21750736   PMID:21795453   PMID:21873635   PMID:22072571   PMID:22242800   PMID:22337907   PMID:22576823  
PMID:22747683   PMID:22932886   PMID:23300763   PMID:23376485   PMID:23533145   PMID:23750785   PMID:24172014   PMID:24246737   PMID:24691024   PMID:25010111   PMID:25198130   PMID:25251318  
PMID:25322275   PMID:25335188   PMID:25636722   PMID:26186194   PMID:26603673   PMID:27300474   PMID:27339896   PMID:27887960   PMID:28514442   PMID:29194043   PMID:29273683   PMID:29679879  
PMID:29922157   PMID:30160799   PMID:30452386   PMID:31103428   PMID:33085168   PMID:33469137   PMID:33660365   PMID:33961781   PMID:35217314   PMID:37745713   PMID:38042488  


Genomics

Comparative Map Data
SERPINA6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381494,304,248 - 94,323,336 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1494,304,248 - 94,323,389 (-)EnsemblGRCh38hg38GRCh38
GRCh371494,770,585 - 94,789,673 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361493,840,338 - 93,859,441 (-)NCBINCBI36Build 36hg18NCBI36
Build 341493,840,338 - 93,859,426NCBI
Celera1474,824,369 - 74,843,477 (-)NCBICelera
Cytogenetic Map14q32.13NCBI
HuRef1474,950,383 - 74,969,481 (-)NCBIHuRef
CHM1_11494,708,390 - 94,727,495 (-)NCBICHM1_1
T2T-CHM13v2.01488,531,534 - 88,550,620 (-)NCBIT2T-CHM13v2.0
Serpina6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912103,612,889 - 103,623,477 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12103,612,889 - 103,623,471 (-)EnsemblGRCm39 Ensembl
GRCm3812103,646,630 - 103,657,218 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12103,646,630 - 103,657,212 (-)EnsemblGRCm38mm10GRCm38
MGSCv3712104,884,842 - 104,895,281 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3612104,047,682 - 104,058,121 (-)NCBIMGSCv36mm8
Celera12104,862,913 - 104,873,376 (-)NCBICelera
Cytogenetic Map12ENCBI
cM Map1252.98NCBI
Serpina6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86128,544,828 - 128,555,064 (-)NCBIGRCr8
mRatBN7.26122,780,040 - 122,790,274 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6122,780,043 - 122,790,349 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6122,920,505 - 122,930,725 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06123,215,781 - 123,226,001 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06122,552,673 - 122,562,896 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06127,523,948 - 127,534,178 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6127,523,906 - 127,534,247 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06136,742,720 - 136,752,950 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46127,911,618 - 127,921,851 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera6120,260,306 - 120,270,532 (-)NCBICelera
Cytogenetic Map6q32NCBI
Serpina6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543816,356,540 - 16,380,872 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543816,356,600 - 16,380,861 (-)NCBIChiLan1.0ChiLan1.0
SERPINA6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21595,461,767 - 95,480,904 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11494,678,417 - 94,688,646 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01474,936,724 - 74,955,799 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11494,269,299 - 94,288,391 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1494,269,299 - 94,288,391 (-)Ensemblpanpan1.1panPan2
SERPINA6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1863,323,896 - 63,341,829 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl863,323,933 - 63,453,708 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha862,900,449 - 62,925,083 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0863,589,497 - 63,614,157 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl863,589,530 - 63,614,404 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1863,266,111 - 63,290,719 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0863,318,270 - 63,342,932 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0863,648,530 - 63,673,205 (-)NCBIUU_Cfam_GSD_1.0
LOC101973017
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864011,314,687 - 11,325,700 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367332,141,392 - 2,148,151 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367332,141,484 - 2,148,129 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SERPINA6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl7115,535,697 - 115,554,570 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.17115,535,552 - 115,554,536 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27122,544,744 - 122,563,955 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SERPINA6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12472,079,084 - 72,098,549 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2472,077,274 - 72,098,154 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605359,312,190 - 59,331,143 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Serpina6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473410,637,515 - 10,651,033 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473410,638,031 - 10,650,297 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SERPINA6
43 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
NM_001756.4(SERPINA6):c.32G>A (p.Trp11Ter) single nucleotide variant Corticosteroid-binding globulin deficiency [RCV000018497] Chr14:94314617 [GRCh38]
Chr14:94780954 [GRCh37]
Chr14:14q32.13
pathogenic
NM_001756.4(SERPINA6):c.344T>A (p.Leu115His) single nucleotide variant Corticosteroid-binding globulin deficiency [RCV000018495]|SERPINA6-related disorder [RCV003934839]|not provided [RCV000479165]|not specified [RCV004689423] Chr14:94314305 [GRCh38]
Chr14:94780642 [GRCh37]
Chr14:14q32.13
pathogenic|likely benign|conflicting interpretations of pathogenicity|uncertain significance
NM_001756.4(SERPINA6):c.1165G>A (p.Asp389Asn) single nucleotide variant Corticosteroid-binding globulin deficiency [RCV000018496]|SERPINA6-related disorder [RCV004757950] Chr14:94304471 [GRCh38]
Chr14:94770808 [GRCh37]
Chr14:14q32.13
pathogenic|likely pathogenic|conflicting interpretations of pathogenicity|uncertain significance
GRCh38/hg38 14q32.11-32.13(chr14:90255156-95274696)x1 copy number loss See cases [RCV000051551] Chr14:90255156..95274696 [GRCh38]
Chr14:90721500..95741033 [GRCh37]
Chr14:89791253..94810786 [NCBI36]
Chr14:14q32.11-32.13
pathogenic
GRCh38/hg38 14q24.2-32.2(chr14:72787506-99596719)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052293]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052293]|See cases [RCV000052293] Chr14:72787506..99596719 [GRCh38]
Chr14:73254214..100063056 [GRCh37]
Chr14:72323967..99132809 [NCBI36]
Chr14:14q24.2-32.2
pathogenic
GRCh38/hg38 14q31.3-32.33(chr14:86094030-106832642)x3 copy number gain See cases [RCV000052295] Chr14:86094030..106832642 [GRCh38]
Chr14:86560374..107240869 [GRCh37]
Chr14:85630127..106311914 [NCBI36]
Chr14:14q31.3-32.33
pathogenic
GRCh38/hg38 14q32.12-32.33(chr14:91455861-106832642)x3 copy number gain See cases [RCV000052296] Chr14:91455861..106832642 [GRCh38]
Chr14:91922205..107240869 [GRCh37]
Chr14:90991958..106311914 [NCBI36]
Chr14:14q32.12-32.33
pathogenic
GRCh38/hg38 14q31.2-32.33(chr14:83912345-106855405)x3 copy number gain See cases [RCV000052294] Chr14:83912345..106855405 [GRCh38]
Chr14:84378689..107263620 [GRCh37]
Chr14:83448442..106334665 [NCBI36]
Chr14:14q31.2-32.33
pathogenic
NM_001756.3(SERPINA6):c.1191C>T (p.Phe397=) single nucleotide variant Malignant melanoma [RCV000070672] Chr14:94304445 [GRCh38]
Chr14:94770782 [GRCh37]
Chr14:93840535 [NCBI36]
Chr14:14q32.13
not provided
NM_001756.3(SERPINA6):c.845G>T (p.Arg282Leu) single nucleotide variant Malignant melanoma [RCV000070673] Chr14:94309775 [GRCh38]
Chr14:94776112 [GRCh37]
Chr14:93845865 [NCBI36]
Chr14:14q32.13
not provided
NM_001756.3(SERPINA6):c.480C>T (p.Phe160=) single nucleotide variant Malignant melanoma [RCV000070674] Chr14:94314169 [GRCh38]
Chr14:94780506 [GRCh37]
Chr14:93850259 [NCBI36]
Chr14:14q32.13
not provided
NM_001756.3(SERPINA6):c.86A>G (p.Tyr29Cys) single nucleotide variant Malignant melanoma [RCV000062825] Chr14:94314563 [GRCh38]
Chr14:94780900 [GRCh37]
Chr14:93850653 [NCBI36]
Chr14:14q32.13
not provided
GRCh38/hg38 14q24.3-32.33(chr14:73655772-106879298)x3 copy number gain See cases [RCV000134000] Chr14:73655772..106879298 [GRCh38]
Chr14:74122475..107287505 [GRCh37]
Chr14:73192228..106358550 [NCBI36]
Chr14:14q24.3-32.33
pathogenic
GRCh38/hg38 14q11.2-32.33(chr14:20151149-106855263)x3 copy number gain See cases [RCV000135543] Chr14:20151149..106855263 [GRCh38]
Chr14:20619308..107263478 [GRCh37]
Chr14:19689148..106334523 [NCBI36]
Chr14:14q11.2-32.33
pathogenic
GRCh38/hg38 14q32.12-32.33(chr14:92540983-104863658)x3 copy number gain See cases [RCV000135896] Chr14:92540983..104863658 [GRCh38]
Chr14:93007328..105329995 [GRCh37]
Chr14:92077081..104401040 [NCBI36]
Chr14:14q32.12-32.33
pathogenic
GRCh38/hg38 14q24.3-32.33(chr14:77222795-106879298)x3 copy number gain See cases [RCV000138230] Chr14:77222795..106879298 [GRCh38]
Chr14:77689138..107287505 [GRCh37]
Chr14:76758891..106358550 [NCBI36]
Chr14:14q24.3-32.33
pathogenic
GRCh38/hg38 14q11.2-32.33(chr14:20043514-106877229)x3 copy number gain See cases [RCV000143373] Chr14:20043514..106877229 [GRCh38]
Chr14:20511673..107285437 [GRCh37]
Chr14:19581513..106356482 [NCBI36]
Chr14:14q11.2-32.33
pathogenic
NM_001756.4(SERPINA6):c.819G>A (p.Met273Ile) single nucleotide variant Inborn genetic diseases [RCV002527027]|not provided [RCV000489584] Chr14:94309801 [GRCh38]
Chr14:94776138 [GRCh37]
Chr14:14q32.13
uncertain significance
GRCh37/hg19 14q11.2-32.33(chr14:19794561-107234280)x3 copy number gain See cases [RCV000446256] Chr14:19794561..107234280 [GRCh37]
Chr14:14q11.2-32.33
pathogenic
GRCh37/hg19 14q23.2-32.33(chr14:62493932-107285437)x3 copy number gain See cases [RCV000448557] Chr14:62493932..107285437 [GRCh37]
Chr14:14q23.2-32.33
pathogenic
GRCh37/hg19 14q11.2-32.33(chr14:20511673-107285437) copy number gain See cases [RCV000512041] Chr14:20511673..107285437 [GRCh37]
Chr14:14q11.2-32.33
pathogenic
GRCh37/hg19 14q32.12-32.13(chr14:93498930-96059698)x3 copy number gain See cases [RCV000511246] Chr14:93498930..96059698 [GRCh37]
Chr14:14q32.12-32.13
uncertain significance
NM_001756.4(SERPINA6):c.130G>A (p.Val44Ile) single nucleotide variant Inborn genetic diseases [RCV003295645] Chr14:94314519 [GRCh38]
Chr14:94780856 [GRCh37]
Chr14:14q32.13
uncertain significance
GRCh37/hg19 14q24.2-32.33(chr14:73750741-107285437)x3 copy number gain See cases [RCV000512497] Chr14:73750741..107285437 [GRCh37]
Chr14:14q24.2-32.33
pathogenic
GRCh37/hg19 14q31.2-32.2(chr14:84783137-96908198)x1 copy number loss not provided [RCV000683625] Chr14:84783137..96908198 [GRCh37]
Chr14:14q31.2-32.2
pathogenic
GRCh37/hg19 14q32.12-32.33(chr14:91969028-107285437)x3 copy number gain not provided [RCV000848687] Chr14:91969028..107285437 [GRCh37]
Chr14:14q32.12-32.33
pathogenic
GRCh37/hg19 14q11.1-32.33(chr14:19000422-107289053)x3 copy number gain not provided [RCV000738412] Chr14:19000422..107289053 [GRCh37]
Chr14:14q11.1-32.33
pathogenic
GRCh37/hg19 14q11.2-32.33(chr14:19280733-107287663)x3 copy number gain not provided [RCV000738413] Chr14:19280733..107287663 [GRCh37]
Chr14:14q11.2-32.33
pathogenic
GRCh37/hg19 14q11.2-32.33(chr14:19327823-107287663)x3 copy number gain not provided [RCV000738414] Chr14:19327823..107287663 [GRCh37]
Chr14:14q11.2-32.33
pathogenic
NM_001756.4(SERPINA6):c.1179G>C (p.Trp393Cys) single nucleotide variant not provided [RCV003234456] Chr14:94304457 [GRCh38]
Chr14:94770794 [GRCh37]
Chr14:14q32.13
uncertain significance
GRCh37/hg19 14q31.2-32.2(chr14:84783523-96907490)x1 copy number loss Deletion syndrome [RCV001004048] Chr14:84783523..96907490 [GRCh37]
Chr14:14q31.2-32.2
pathogenic
NM_001756.4(SERPINA6):c.378C>T (p.Thr126=) single nucleotide variant SERPINA6-related disorder [RCV003975779]|not provided [RCV001641889] Chr14:94314271 [GRCh38]
Chr14:94780608 [GRCh37]
Chr14:14q32.13
benign
NM_001756.4(SERPINA6):c.539G>A (p.Gly180Glu) single nucleotide variant Corticosteroid-binding globulin deficiency [RCV001330835] Chr14:94314110 [GRCh38]
Chr14:94780447 [GRCh37]
Chr14:14q32.13
uncertain significance
NM_001756.4(SERPINA6):c.164_165del (p.Val55fs) deletion Corticosteroid-binding globulin deficiency [RCV001391242] Chr14:94314484..94314485 [GRCh38]
Chr14:94780821..94780822 [GRCh37]
Chr14:14q32.13
likely pathogenic
GRCh37/hg19 14q32.12-32.13(chr14:94442454-95185710) copy number gain not specified [RCV002052454] Chr14:94442454..95185710 [GRCh37]
Chr14:14q32.12-32.13
uncertain significance
GRCh37/hg19 14q32.12-32.13(chr14:94400492-96192218) copy number gain not specified [RCV002052453] Chr14:94400492..96192218 [GRCh37]
Chr14:14q32.12-32.13
uncertain significance
NC_000014.8:g.(?_93687728)_(95560403_?)del deletion DICER1-related tumor predisposition [RCV002044285] Chr14:93687728..95560403 [GRCh37]
Chr14:14q32.12-32.13
likely pathogenic
GRCh37/hg19 14q31.3-32.13(chr14:88345625-94773741) copy number loss not specified [RCV002053117] Chr14:88345625..94773741 [GRCh37]
Chr14:14q31.3-32.13
pathogenic
NC_000014.8:g.(?_90429459)_(97347545_?)dup duplication not provided [RCV003109490] Chr14:90429459..97347545 [GRCh37]
Chr14:14q32.11-32.2
uncertain significance
NC_000014.8:g.(?_90429459)_(94856914_?)dup duplication Achondrogenesis, type IA [RCV003113413] Chr14:90429459..94856914 [GRCh37]
Chr14:14q32.11-32.13
uncertain significance
GRCh37/hg19 14q13.3-32.33(chr14:37671058-106985955)x2 copy number gain See cases [RCV002286356] Chr14:37671058..106985955 [GRCh37]
Chr14:14q13.3-32.33
pathogenic
NM_001756.4(SERPINA6):c.847G>C (p.Asp283His) single nucleotide variant not provided [RCV003129419] Chr14:94309773 [GRCh38]
Chr14:94776110 [GRCh37]
Chr14:14q32.13
uncertain significance
GRCh37/hg19 14q31.2-32.33(chr14:84537502-107285437)x3 copy number gain not provided [RCV002472581] Chr14:84537502..107285437 [GRCh37]
Chr14:14q31.2-32.33
pathogenic
GRCh37/hg19 14q32.12-32.13(chr14:94637559-95522984)x3 copy number gain not provided [RCV002472422] Chr14:94637559..95522984 [GRCh37]
Chr14:14q32.12-32.13
uncertain significance
GRCh37/hg19 14q31.1-32.2(chr14:81593708-97059276)x3 copy number gain not provided [RCV002472541] Chr14:81593708..97059276 [GRCh37]
Chr14:14q31.1-32.2
likely pathogenic
NM_001756.4(SERPINA6):c.97A>G (p.Ser33Gly) single nucleotide variant Inborn genetic diseases [RCV002751730] Chr14:94314552 [GRCh38]
Chr14:94780889 [GRCh37]
Chr14:14q32.13
uncertain significance
NM_001756.4(SERPINA6):c.721A>G (p.Ser241Gly) single nucleotide variant Inborn genetic diseases [RCV002910425] Chr14:94309899 [GRCh38]
Chr14:94776236 [GRCh37]
Chr14:14q32.13
uncertain significance
NM_001756.4(SERPINA6):c.193A>G (p.Ile65Val) single nucleotide variant Inborn genetic diseases [RCV002950442] Chr14:94314456 [GRCh38]
Chr14:94780793 [GRCh37]
Chr14:14q32.13
uncertain significance
NM_001756.4(SERPINA6):c.93C>G (p.Asn31Lys) single nucleotide variant Inborn genetic diseases [RCV002823138] Chr14:94314556 [GRCh38]
Chr14:94780893 [GRCh37]
Chr14:14q32.13
uncertain significance
NM_001756.4(SERPINA6):c.665A>T (p.Tyr222Phe) single nucleotide variant Inborn genetic diseases [RCV002821496] Chr14:94309955 [GRCh38]
Chr14:94776292 [GRCh37]
Chr14:14q32.13
uncertain significance
NM_001756.4(SERPINA6):c.1010A>G (p.Asp337Gly) single nucleotide variant Inborn genetic diseases [RCV002641224] Chr14:94306093 [GRCh38]
Chr14:94772430 [GRCh37]
Chr14:14q32.13
uncertain significance
NM_001756.4(SERPINA6):c.43A>G (p.Ser15Gly) single nucleotide variant Inborn genetic diseases [RCV002713766] Chr14:94314606 [GRCh38]
Chr14:94780943 [GRCh37]
Chr14:14q32.13
uncertain significance
NM_001756.4(SERPINA6):c.164T>C (p.Val55Ala) single nucleotide variant Inborn genetic diseases [RCV002712256] Chr14:94314485 [GRCh38]
Chr14:94780822 [GRCh37]
Chr14:14q32.13
uncertain significance
NM_001756.4(SERPINA6):c.710C>T (p.Ser237Leu) single nucleotide variant Inborn genetic diseases [RCV002719455] Chr14:94309910 [GRCh38]
Chr14:94776247 [GRCh37]
Chr14:14q32.13
uncertain significance
NM_001756.4(SERPINA6):c.997C>T (p.Arg333Cys) single nucleotide variant Inborn genetic diseases [RCV003351690] Chr14:94306106 [GRCh38]
Chr14:94772443 [GRCh37]
Chr14:14q32.13
uncertain significance
GRCh37/hg19 14q23.1-32.33(chr14:58894502-107227240)x3 copy number gain not provided [RCV003485036] Chr14:58894502..107227240 [GRCh37]
Chr14:14q23.1-32.33
pathogenic
GRCh37/hg19 14q31.3-32.33(chr14:88580184-107285437)x3 copy number gain not provided [RCV003485051] Chr14:88580184..107285437 [GRCh37]
Chr14:14q31.3-32.33
pathogenic
NM_001756.4(SERPINA6):c.738G>A (p.Ser246=) single nucleotide variant SERPINA6-related disorder [RCV003982309] Chr14:94309882 [GRCh38]
Chr14:94776219 [GRCh37]
Chr14:14q32.13
benign
NM_001756.4(SERPINA6):c.936C>T (p.Leu312=) single nucleotide variant SERPINA6-related disorder [RCV003977332] Chr14:94306167 [GRCh38]
Chr14:94772504 [GRCh37]
Chr14:14q32.13
benign
NM_001756.4(SERPINA6):c.1011C>T (p.Asp337=) single nucleotide variant SERPINA6-related disorder [RCV003964368] Chr14:94306092 [GRCh38]
Chr14:94772429 [GRCh37]
Chr14:14q32.13
benign
NM_001756.4(SERPINA6):c.1146C>G (p.Pro382=) single nucleotide variant SERPINA6-related disorder [RCV003933843] Chr14:94304490 [GRCh38]
Chr14:94770827 [GRCh37]
Chr14:14q32.13
likely benign
NM_001756.4(SERPINA6):c.804G>A (p.Pro268=) single nucleotide variant SERPINA6-related disorder [RCV003924317] Chr14:94309816 [GRCh38]
Chr14:94776153 [GRCh37]
Chr14:14q32.13
benign
NM_001756.4(SERPINA6):c.885-6G>A single nucleotide variant SERPINA6-related disorder [RCV003909417] Chr14:94306224 [GRCh38]
Chr14:94772561 [GRCh37]
Chr14:14q32.13
likely benign
NM_001756.4(SERPINA6):c.113G>T (p.Gly38Val) single nucleotide variant Inborn genetic diseases [RCV004453250] Chr14:94314536 [GRCh38]
Chr14:94780873 [GRCh37]
Chr14:14q32.13
uncertain significance
NM_001756.4(SERPINA6):c.1037T>C (p.Val346Ala) single nucleotide variant Inborn genetic diseases [RCV004453248] Chr14:94304599 [GRCh38]
Chr14:94770936 [GRCh37]
Chr14:14q32.13
uncertain significance
NM_001756.4(SERPINA6):c.829A>T (p.Ile277Phe) single nucleotide variant Inborn genetic diseases [RCV004453254] Chr14:94309791 [GRCh38]
Chr14:94776128 [GRCh37]
Chr14:14q32.13
uncertain significance
NM_001756.4(SERPINA6):c.1138A>C (p.Asn380His) single nucleotide variant Inborn genetic diseases [RCV004453249] Chr14:94304498 [GRCh38]
Chr14:94770835 [GRCh37]
Chr14:14q32.13
uncertain significance
NM_001756.4(SERPINA6):c.452A>G (p.Tyr151Cys) single nucleotide variant Inborn genetic diseases [RCV004453251] Chr14:94314197 [GRCh38]
Chr14:94780534 [GRCh37]
Chr14:14q32.13
uncertain significance
NM_001756.4(SERPINA6):c.607T>C (p.Phe203Leu) single nucleotide variant Inborn genetic diseases [RCV004453252] Chr14:94314042 [GRCh38]
Chr14:94780379 [GRCh37]
Chr14:14q32.13
uncertain significance
NM_001756.4(SERPINA6):c.849C>G (p.Asp283Glu) single nucleotide variant Inborn genetic diseases [RCV004667135] Chr14:94309771 [GRCh38]
Chr14:94776108 [GRCh37]
Chr14:14q32.13
uncertain significance
NM_001756.4(SERPINA6):c.617C>A (p.Thr206Lys) single nucleotide variant Inborn genetic diseases [RCV004665955] Chr14:94310003 [GRCh38]
Chr14:94776340 [GRCh37]
Chr14:14q32.13
uncertain significance
NM_001756.4(SERPINA6):c.638T>G (p.Leu213Arg) single nucleotide variant Inborn genetic diseases [RCV004667136] Chr14:94309982 [GRCh38]
Chr14:94776319 [GRCh37]
Chr14:14q32.13
uncertain significance
NM_001756.4(SERPINA6):c.46G>T (p.Gly16Cys) single nucleotide variant Inborn genetic diseases [RCV004667137] Chr14:94314603 [GRCh38]
Chr14:94780940 [GRCh37]
Chr14:14q32.13
uncertain significance
NM_001756.4(SERPINA6):c.694C>T (p.Pro232Ser) single nucleotide variant Inborn genetic diseases [RCV004665954] Chr14:94309926 [GRCh38]
Chr14:94776263 [GRCh37]
Chr14:14q32.13
uncertain significance
NM_001756.4(SERPINA6):c.1111A>G (p.Thr371Ala) single nucleotide variant Inborn genetic diseases [RCV004665953] Chr14:94304525 [GRCh38]
Chr14:94770862 [GRCh37]
Chr14:14q32.13
likely benign
NM_001756.4(SERPINA6):c.1112C>T (p.Thr371Met) single nucleotide variant not provided [RCV004761053]   uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:600
Count of miRNA genes:441
Interacting mature miRNAs:464
Transcripts:ENST00000341584, ENST00000555056, ENST00000557225
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
597353434GWAS1449508_Hbody height QTL GWAS1449508 (human)5e-21body height (VT:0001253)body height (CMO:0000106)149430729794307298Human
597617854GWAS1674714_Hfemur fracture QTL GWAS1674714 (human)3e-11femur fracture149431105594311056Human
597347242GWAS1443316_Hbody fat percentage QTL GWAS1443316 (human)1e-15body fat mass (VT:0010482)body fat percentage (CMO:0000302)149431828194318282Human
597103490GWAS1199564_Hserum alanine aminotransferase measurement QTL GWAS1199564 (human)5e-12serum alanine aminotransferase measurementserum alanine aminotransferase activity level (CMO:0000575)149431828194318282Human
597274309GWAS1370383_Hprotein Z-dependent protease inhibitor measurement QTL GWAS1370383 (human)1e-13protein Z-dependent protease inhibitor measurement149432315894323159Human
597141976GWAS1238050_Hcortisone measurement QTL GWAS1238050 (human)1e-15cortisone measurement149432278094322781Human

Markers in Region
RH17576  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371494,770,712 - 94,770,849UniSTSGRCh37
Build 361493,840,465 - 93,840,602RGDNCBI36
Celera1474,824,496 - 74,824,633RGD
Cytogenetic Map14q32.1UniSTS
HuRef1474,950,510 - 74,950,647UniSTS
GeneMap99-GB4 RH Map14252.33UniSTS
D14S1141  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371494,788,812 - 94,788,902UniSTSGRCh37
Build 361493,858,565 - 93,858,655RGDNCBI36
Celera1474,842,601 - 74,842,691RGD
Cytogenetic Map14q32.1UniSTS
HuRef1474,968,605 - 74,968,695UniSTS
GDB:378193  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371494,788,812 - 94,788,902UniSTSGRCh37
Build 361493,858,565 - 93,858,655RGDNCBI36
Celera1474,842,601 - 74,842,691RGD
Cytogenetic Map14q32.1UniSTS
HuRef1474,968,605 - 74,968,695UniSTS
SHGC-12744  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371494,770,589 - 94,770,741UniSTSGRCh37
Build 361493,840,342 - 93,840,494RGDNCBI36
Celera1474,824,373 - 74,824,525RGD
Cytogenetic Map14q32.1UniSTS
HuRef1474,950,387 - 74,950,539UniSTS
Stanford-G3 RH Map143403.0UniSTS
NCBI RH Map14980.2UniSTS
GeneMap99-G3 RH Map143952.0UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
426 1437 842 681 1711 940 1422 2 549 892 457 958 3425 2464 15 1049 626 1200 832 99

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_011796 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001756 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047431827 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054329028 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054376844 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AK225591 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK290821 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK313760 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL117259 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AV689566 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC017462 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC036818 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC056259 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC058021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471061 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068264 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  J02943 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M31662 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG652288 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENST00000341584   ⟹   ENSP00000342850
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1494,304,248 - 94,323,336 (-)Ensembl
Ensembl Acc Id: ENST00000555056   ⟹   ENSP00000451045
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1494,304,248 - 94,323,319 (-)Ensembl
Ensembl Acc Id: ENST00000557225   ⟹   ENSP00000452018
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1494,314,240 - 94,323,389 (-)Ensembl
RefSeq Acc Id: NM_001756   ⟹   NP_001747
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381494,304,248 - 94,323,336 (-)NCBI
GRCh371494,770,585 - 94,789,688 (-)ENTREZGENE
Build 361493,840,338 - 93,859,441 (-)NCBI Archive
HuRef1474,950,383 - 74,969,481 (-)ENTREZGENE
CHM1_11494,708,390 - 94,727,495 (-)NCBI
T2T-CHM13v2.01488,531,534 - 88,550,620 (-)NCBI
Sequence:
RefSeq Acc Id: XM_047431827   ⟹   XP_047287783
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381494,304,248 - 94,323,336 (-)NCBI
RefSeq Acc Id: XM_054376844   ⟹   XP_054232819
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01488,531,534 - 88,550,620 (-)NCBI
RefSeq Acc Id: NP_001747   ⟸   NM_001756
- Peptide Label: precursor
- UniProtKB: P08185 (UniProtKB/Swiss-Prot),   A8K456 (UniProtKB/Swiss-Prot),   Q7Z2Q9 (UniProtKB/Swiss-Prot),   A0A2Z4LCH4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSP00000451045   ⟸   ENST00000555056
Ensembl Acc Id: ENSP00000452018   ⟸   ENST00000557225
Ensembl Acc Id: ENSP00000342850   ⟸   ENST00000341584
RefSeq Acc Id: XP_047287783   ⟸   XM_047431827
- Peptide Label: isoform X1
- UniProtKB: A0A2Z4LCH4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054232819   ⟸   XM_054376844
- Peptide Label: isoform X1
- UniProtKB: A0A2Z4LCH4 (UniProtKB/TrEMBL)
Protein Domains
SERPIN

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P08185-F1-model_v2 AlphaFold P08185 1-405 view protein structure

Promoters
RGD ID:7228505
Promoter ID:EPDNEW_H19998
Type:initiation region
Name:SERPINA6_1
Description:serpin family A member 6
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381494,323,336 - 94,323,396EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:1540 AgrOrtholog
COSMIC SERPINA6 COSMIC
Ensembl Genes ENSG00000170099 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSG00000277405 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000341584 ENTREZGENE
  ENST00000341584.4 UniProtKB/Swiss-Prot
  ENST00000555056.1 UniProtKB/TrEMBL
  ENST00000557225.1 UniProtKB/TrEMBL
  ENST00000621384.2 UniProtKB/Swiss-Prot
  ENST00000630843.1 UniProtKB/TrEMBL
  ENST00000631236.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.39.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.497.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000170099 GTEx
  ENSG00000277405 GTEx
HGNC ID HGNC:1540 ENTREZGENE
Human Proteome Map SERPINA6 Human Proteome Map
InterPro Serpin_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Serpin_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Serpin_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Serpin_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Serpin_sf_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Serpin_sf_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:866 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 866 ENTREZGENE
OMIM 122500 OMIM
PANTHER CORTICOSTEROID-BINDING GLOBULIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11461 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Serpin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA35033 PharmGKB, RGD
PRINTS LEUSERPINII UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE SERPIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SERPIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF56574 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A2Z4LCH4 ENTREZGENE, UniProtKB/TrEMBL
  A8K456 ENTREZGENE
  CBG_HUMAN UniProtKB/Swiss-Prot
  G3V350_HUMAN UniProtKB/TrEMBL
  G3V4V7_HUMAN UniProtKB/TrEMBL
  P08185 ENTREZGENE
  Q7Z2Q9 ENTREZGENE
UniProt Secondary A8K456 UniProtKB/Swiss-Prot
  Q7Z2Q9 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-04-12 SERPINA6  serpin family A member 6  SERPINA6  serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6  Symbol and/or name change 5135510 APPROVED