Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-catechin | multiple interactions | EXP | | 6480464 | [Catechin co-treated with Grape Seed Proanthocyanidins] results in increased expression of RAP2C mRNA | CTD | PMID:24763279 | 1,2-dimethylhydrazine | decreases expression | ISO | RGD:1619982 | 6480464 | 1, 2-Dimethylhydrazine results in decreased expression of RAP2C mRNA | CTD | PMID:22206623 | 1,3,5-trinitro-1,3,5-triazinane | decreases expression | ISO | RGD:1588562 | 6480464 | cyclonite results in decreased expression of RAP2C mRNA | CTD | PMID:25559034 | 2,2',4,4',5,5'-hexachlorobiphenyl | multiple interactions | ISO | RGD:1619982 | 6480464 | [2 more ... | CTD | PMID:25510870 | 2,2',5,5'-tetrachlorobiphenyl | multiple interactions | ISO | RGD:1619982 | 6480464 | [2 more ... | CTD | PMID:25510870 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:1619982 | 6480464 | Tetrachlorodibenzodioxin affects the expression of RAP2C mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:1588562 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of RAP2C mRNA | CTD | PMID:32109520 | 2,3,7,8-Tetrachlorodibenzofuran | decreases expression | ISO | RGD:1588562 | 6480464 | 2 more ... | CTD | PMID:32109520 | acetamide | decreases expression | ISO | RGD:1588562 | 6480464 | acetamide results in decreased expression of RAP2C mRNA | CTD | PMID:31881176 | acrylamide | increases expression | ISO | RGD:1588562 | 6480464 | Acrylamide results in increased expression of RAP2C mRNA | CTD | PMID:28959563 | aflatoxin B1 | decreases methylation | EXP | | 6480464 | Aflatoxin B1 results in decreased methylation of RAP2C gene | CTD | PMID:27153756 | arsenous acid | increases expression | EXP | | 6480464 | Arsenic Trioxide results in increased expression of RAP2C mRNA | CTD | PMID:20458559 | benzo[a]pyrene | affects methylation | EXP | | 6480464 | Benzoapyrene affects the methylation of RAP2C promoter | CTD | PMID:27901495 | benzo[a]pyrene | increases methylation | EXP | | 6480464 | Benzoapyrene results in increased methylation of RAP2C 5' UTR | CTD | PMID:27901495 | bisphenol A | affects expression | ISO | RGD:1588562 | 6480464 | bisphenol A affects the expression of RAP2C mRNA | CTD | PMID:25181051 | bisphenol A | increases expression | ISO | RGD:1588562 | 6480464 | bisphenol A results in increased expression of RAP2C mRNA | CTD | PMID:33296240 | choline | multiple interactions | ISO | RGD:1619982 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of RAP2C gene | CTD | PMID:20938992 | cobalt dichloride | increases expression | EXP | | 6480464 | cobaltous chloride results in increased expression of RAP2C mRNA | CTD | PMID:19376846 | diarsenic trioxide | increases expression | EXP | | 6480464 | Arsenic Trioxide results in increased expression of RAP2C mRNA | CTD | PMID:20458559 | dibutyl phthalate | decreases expression | ISO | RGD:1619982 | 6480464 | Dibutyl Phthalate results in decreased expression of RAP2C mRNA | CTD | PMID:21266533 | finasteride | increases expression | ISO | RGD:1588562 | 6480464 | Finasteride results in increased expression of RAP2C mRNA | CTD | PMID:24136188 | flutamide | increases expression | ISO | RGD:1588562 | 6480464 | Flutamide results in increased expression of RAP2C mRNA | CTD | PMID:24136188 | folic acid | multiple interactions | ISO | RGD:1619982 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of RAP2C gene | CTD | PMID:20938992 | L-methionine | multiple interactions | ISO | RGD:1619982 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of RAP2C gene | CTD | PMID:20938992 | lead diacetate | multiple interactions | EXP | | 6480464 | [lead acetate co-treated with zinc protoporphyrin] results in decreased expression of RAP2C mRNA | CTD | PMID:22839698 | paracetamol | affects expression | ISO | RGD:1619982 | 6480464 | Acetaminophen affects the expression of RAP2C mRNA | CTD | PMID:17562736 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of RAP2C mRNA | CTD | PMID:21420995 | PCB138 | multiple interactions | ISO | RGD:1619982 | 6480464 | [2 more ... | CTD | PMID:25510870 | pirinixic acid | increases expression | ISO | RGD:1619982 | 6480464 | pirinixic acid results in increased expression of RAP2C mRNA | CTD | PMID:17426115 | sunitinib | increases expression | EXP | | 6480464 | Sunitinib results in increased expression of RAP2C mRNA | CTD | PMID:31533062 | urethane | decreases expression | EXP | | 6480464 | Urethane results in decreased expression of RAP2C mRNA | CTD | PMID:28818685 | valproic acid | affects expression | EXP | | 6480464 | Valproic Acid affects the expression of RAP2C mRNA | CTD | PMID:25979313 | valproic acid | increases expression | EXP | | 6480464 | Valproic Acid results in increased expression of RAP2C mRNA | CTD | PMID:23527032, PMID:24935251 | zinc protoporphyrin | multiple interactions | EXP | | 6480464 | [lead acetate co-treated with zinc protoporphyrin] results in decreased expression of RAP2C mRNA | CTD | PMID:22839698 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
 |
Welcome {{ username}}
Message Center
{{ messageCount }} Messages
Watched Genes
{{$index + 1}}. {{ watchedObject.symbol }} (RGD ID:{{watchedObject.rgdId}})
Watched Ontology Terms
{{gene.symbol}}: {{ gene.description }}
|
| Save what matters to you |
| {{ loginError }} |
| Sign in with your RGD account |
| Create New Account | Recover Password |
Analyze GeneStrainQTL List |
 Gene Annotator (Functional Annotation) unavailable |
 Gene Annotator (Annotation Distribution) unavailable |
 Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable |
Gene Annotator (Functional Annotation) |
Gene Annotator (Annotation Distribution) |
Variant Visualizer (Genomic Variants) |
 InterViewer (Protein-Protein Interactions) unavailable |
 Gviewer (Genome Viewer) unavailable |
 Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable |
InterViewer (Protein-Protein Interactions) |
GViewer (Genome Viewer) |
Variant Visualizer (Damaging Variants) |
 Gene Annotator (Annotation Comparison) unavailable |
 OLGA (Gene List Generator) unavailable |
 |
Gene Annotator (Annotation Comparison) |
OLGA (Gene List Generator) |
Excel (Download) |
 MOET (Multi-Ontology Enrichement) unavailable |
 GOLF (Gene-Ortholog Location Finder) unavailable |
|
MOET (Multi-Ontology Enrichement) |
GOLF (Gene-Ortholog Location Finder) |
|
||||||||
Gene Ontology Annotations Click to see Annotation Detail View
Biological Process
Cellular Component
Molecular Function
Phenotype Annotations Click to see Annotation Detail View
Human Phenotype
Gene-Chemical Interaction Annotations
Click to see Annotation Detail View
|
|
|
Gene Ontology Annotations
Click to see Annotation Detail View
Biological Process
Cellular Component
|
|
|
Molecular Function
|
|
|
Phenotype Annotations
Click to see Annotation Detail View
References
References - curated
| 1. | GOA_HUMAN data from the GO Consortium |
| 2. | RGD automated import pipeline for gene-chemical interactions |
| 3. | Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11. |
Additional References at PubMed
| PMID:15146197 | PMID:15489334 | PMID:15772651 | PMID:16213650 | PMID:16344560 | PMID:16540189 | PMID:17447155 | PMID:17690704 | PMID:19056867 | PMID:19322201 | PMID:19784953 | PMID:20458337 |
| PMID:21668950 | PMID:21873635 | PMID:22797597 | PMID:23885123 | PMID:24561123 | PMID:26344197 | PMID:26496610 | PMID:28514442 | PMID:28714326 | PMID:29212245 | PMID:29509190 | PMID:29564676 |
| PMID:30194290 | PMID:31091453 | PMID:31527615 | PMID:31541458 | PMID:31586073 | PMID:32296183 | PMID:33001583 |
Genomics
