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Gene: RUBCN (rubicon autophagy regulator) Homo sapiens
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Symbol: RUBCN
Name: rubicon autophagy regulator
RGD ID: 1353596
Description: Predicted to have phosphatidylinositol phosphate binding activity. Involved in negative regulation of autophagosome maturation; negative regulation of endocytosis; and negative regulation of phosphatidylinositol 3-kinase activity. Localizes to cytosol; endosome; and nucleoplasm. Implicated in autosomal recessive spinocerebellar ataxia 15.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: baron; beclin-1 associated RUN domain containing protein; KIAA0226; rubicon; RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein; run domain Beclin-1 interacting and cystein-rich containing protein; run domain Beclin-1 interacting and cysteine-rich containing protein; RUN domain protein as Beclin 1-interacting and cysteine-rich containing; rundataxin; SCAR15
Orthologs:
Mus musculus (house mouse) : Rubcn (RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein)  MGI  Alliance
Rattus norvegicus (Norway rat) : Rubcn (rubicon autophagy regulator)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rubcn (rubicon autophagy regulator)
Pan paniscus (bonobo/pygmy chimpanzee) : RUBCN (rubicon autophagy regulator)
Canis lupus familiaris (dog) : RUBCN (rubicon autophagy regulator)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rubcn (rubicon autophagy regulator)
Sus scrofa (pig) : RUBCN (rubicon autophagy regulator)
Chlorocebus sabaeus (African green monkey) : RUBCN (rubicon autophagy regulator)
Heterocephalus glaber (naked mole-rat) : Rubcn (rubicon autophagy regulator)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl3197,668,867 - 197,749,727 (-)EnsemblGRCh38hg38GRCh38
GRCh383197,668,867 - 197,749,727 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh373197,398,259 - 197,476,568 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363198,882,656 - 198,948,170 (-)NCBINCBI36hg18NCBI36
Celera3196,014,953 - 196,093,675 (-)NCBI
Cytogenetic Map3q29NCBI
HuRef3194,700,863 - 194,779,394 (-)NCBIHuRef
CHM1_13197,369,087 - 197,447,452 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


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References - uncurated

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RNA-SEQ Expression

Sequence

Nucleotide Sequences
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Nomenclature History
 
More on RUBCN
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1353596
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.