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Gene: MAGEA3 (MAGE family member A3) Homo sapiens
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Symbol: MAGEA3
Name: MAGE family member A3
Description: Exhibits caspase binding activity. Involved in negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway; and negative regulation of protein processing. Localizes to the endoplasmic reticulum.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: antigen MZ2-D; cancer/testis antigen 1.3; cancer/testis antigen family 1, member 3; CT1.3; HIP8; HYPD; MAGE-3 antigen; MAGE3; MAGEA6; melanoma antigen family A, 3; melanoma antigen family A3; melanoma-associated antigen 3; MGC14613
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 EnsemblX152,698,767 - 152,702,347 (+)Ensembl
GRCh38X152,698,742 - 152,702,347 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X151,934,652 - 151,938,250 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X151,685,308 - 151,688,896 (-)NCBINCBI36hg18NCBI36
Build 34X151,605,220 - 151,608,808NCBI
CeleraX152,112,403 - 152,115,991 (+)NCBI
Cytogenetic MapXq28NCBI
HuRefX140,736,139 - 140,739,870 (-)NCBIHuRef
CHM1_1X151,741,886 - 151,745,481 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on MAGEA3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1353296
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.