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Gene: MAGEB3 (MAGE family member B3) Homo sapiens
Symbol: MAGEB3
Name: MAGE family member B3
Description: This gene is a MAGE-B subfamily member of the MAGE gene family. MAGE family member proteins direct the expression of tumor antigens recognized on a human melanoma by autologous cytolytic T lymphocytes. There are two known clusters of MAGE genes on chromosome X. The members of the MAGE-A subfamily are located in the Xq28 region, while the members of the MAGE-B subfamily are clustered in the Xp21 region. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: cancer/testis antigen family 3, member 5; CT3.5; MAGE-B3 antigen; melanoma antigen family B, 3; melanoma antigen family B3; melanoma-associated antigen B3
Mus musculus (house mouse) : Gm44 (predicted gene 44)  MGI  Alliance
Rattus norvegicus (Norway rat) : Mageb3 (MAGE family member B3)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : MAGEB3 (MAGE family member B3)
Canis lupus familiaris (dog) : MAGEB3 (MAGE family member B3)
Sus scrofa (pig) : MAGEB3 (MAGE family member B3)
Chlorocebus sabaeus (green monkey) : MAGEB3 (MAGE family member B3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 EnsemblX30,230,436 - 30,237,492 (+)Ensembl
GRCh38X30,230,436 - 30,237,493 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X30,248,553 - 30,255,612 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X30,158,474 - 30,165,528 (+)NCBINCBI36hg18NCBI36
Build 34X30,008,209 - 30,015,264NCBI
CeleraX34,370,173 - 34,377,229 (+)NCBI
Cytogenetic MapXp21.2NCBI
HuRefX27,985,506 - 27,992,557 (+)NCBIHuRef
CHM1_1X30,279,495 - 30,286,489 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on MAGEB3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1353042
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.