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Gene: SETD4 (SET domain containing 4) Homo sapiens
Symbol: SETD4
Name: SET domain containing 4
RGD ID: 1353006
Description: Predicted to have protein-lysine N-methyltransferase activity. Predicted to be involved in peptidyl-lysine monomethylation and peptidyl-lysine trimethylation. Localizes to cytosol and nucleus; INTERACTS WITH 3-isobutyl-1-methyl-7H-xanthine; acetaldehyde; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C21orf18; C21orf27; SET domain-containing protein 4
Mus musculus (house mouse) : Setd4 (SET domain containing 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Setd4 (SET domain containing 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Setd4 (SET domain containing 4)
Pan paniscus (bonobo/pygmy chimpanzee) : SETD4 (SET domain containing 4)
Canis lupus familiaris (dog) : SETD4 (SET domain containing 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Setd4 (SET domain containing 4)
Sus scrofa (pig) : SETD4 (SET domain containing 4)
Chlorocebus sabaeus (African green monkey) : SETD4 (SET domain containing 4)
Heterocephalus glaber (naked mole-rat) : Setd4 (SET domain containing 4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl2136,034,541 - 36,079,389 (-)EnsemblGRCh38hg38GRCh38
GRCh382136,034,541 - 36,061,037 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372137,406,839 - 37,432,869 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362136,328,709 - 36,358,576 (-)NCBINCBI36hg18NCBI36
Build 342136,328,709 - 36,358,576NCBI
Celera2122,605,727 - 22,631,704 (-)NCBI
Cytogenetic Map21q22.12NCBI
HuRef2122,885,338 - 22,911,268 (-)NCBIHuRef
CHM1_12136,968,665 - 36,994,919 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on SETD4
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1353006
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.