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Gene: CD320 (CD320 molecule) Homo sapiens
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Symbol: CD320
Name: CD320 molecule
RGD ID: 1352822
Description: Exhibits calcium ion binding activity and cobalamin binding activity. Involved in B cell costimulation; cobalamin transport; and positive regulation of B cell proliferation. Localizes to endoplasmic reticulum and integral component of plasma membrane. Implicated in methylmalonic acidemia due to transcobalamin receptor defect.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 8D6; 8D6 antigen; 8D6A; CD320 antigen; FDC-signaling molecule 8D6; FDC-SM-8D6; TCBLR; TCN2R; transcobalamin 2 receptor; transcobalamin receptor
Orthologs:
Mus musculus (house mouse) : Cd320 (CD320 antigen)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cd320 (CD320 molecule)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cd320 (CD320 molecule)
Pan paniscus (bonobo/pygmy chimpanzee) : CD320 (CD320 molecule)
Canis lupus familiaris (dog) : CD320 (CD320 molecule)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cd320 (CD320 molecule)
Sus scrofa (pig) : CD320 (CD320 molecule)
Chlorocebus sabaeus (African green monkey) : CD320 (CD320 molecule)
Heterocephalus glaber (naked mole-rat) : Cd320 (CD320 molecule)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl198,302,127 - 8,308,358 (-)EnsemblGRCh38hg38GRCh38
GRCh38198,302,127 - 8,308,358 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37198,367,011 - 8,373,439 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36198,273,011 - 8,279,239 (-)NCBINCBI36hg18NCBI36
Build 34198,273,010 - 8,279,239NCBI
Celera198,223,534 - 8,229,765 (-)NCBI
Cytogenetic Map19p13.2NCBI
HuRef198,021,040 - 8,027,272 (-)NCBIHuRef
CHM1_1198,366,510 - 8,372,742 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on CD320
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1352822
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.