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Gene: C21orf91 (chromosome 21 open reading frame 91) Homo sapiens
Symbol: C21orf91
Name: chromosome 21 open reading frame 91
RGD ID: 1352771
Description: Predicted to be involved in cerebral cortex neuron differentiation and positive regulation of dendritic spine development; INTERACTS WITH 17beta-estradiol; aflatoxin B1; aflatoxin M1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C21orf14; C21orf38; cold sore susceptibility gene 1; CSSG1; DKFZp781D1223; early undifferentiated retina and lens; EURL; protein EURL homolog; YG81
Mus musculus (house mouse) : D16Ertd472e (DNA segment, Chr 16, ERATO Doi 472, expressed)  MGI  Alliance
Rattus norvegicus (Norway rat) : RGD1563888 (similar to DNA segment, Chr 16, ERATO Doi 472, expressed)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : LOC102013799 (chromosome unknown open reading frame, human C21orf91)
Pan paniscus (bonobo/pygmy chimpanzee) : C21H21orf91 (chromosome 21 C21orf91 homolog)
Canis lupus familiaris (dog) : C31H21orf91 (chromosome 31 C21orf91 homolog)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : CUNH21orf91 (chromosome unknown C21orf91 homolog)
Sus scrofa (pig) : C13H21orf91 (chromosome 13 C21orf91 homolog)
Chlorocebus sabaeus (African green monkey) : C2H21orf91 (chromosome 2 open reading frame, human C21orf91)
Heterocephalus glaber (naked mole-rat) : CUNH21orf91 (chromosome unknown C21orf91 homolog)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl2117,788,974 - 17,819,386 (-)EnsemblGRCh38hg38GRCh38
GRCh382117,788,974 - 17,819,356 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372119,161,284 - 19,191,703 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362118,083,155 - 18,113,574 (-)NCBINCBI36hg18NCBI36
Build 342118,086,994 - 18,112,513NCBI
Celera214,339,748 - 4,370,167 (-)NCBI
Cytogenetic Map21q21.1NCBI
HuRef214,550,222 - 4,580,642 (-)NCBIHuRef
CHM1_12118,722,458 - 18,752,865 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on C21orf91
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1352771
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.