CA10 (carbonic anhydrase 10) - Rat Genome Database

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Gene: CA10 (carbonic anhydrase 10) Homo sapiens
Analyze
Symbol: CA10
Name: carbonic anhydrase 10
RGD ID: 1352724
HGNC Page HGNC
Description: Predicted to have hydro-lyase activity. Predicted to be involved in one-carbon metabolic process.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CA-RP X; CA-RPX; carbonic anhydrase X; carbonic anhydrase-related protein 10; carbonic anhydrase-related protein X; CARP X; CARPX; cerebral protein 15; cerebral protein-15; HUCEP-15
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1751,630,313 - 52,160,017 (-)EnsemblGRCh38hg38GRCh38
GRCh381751,630,313 - 52,160,023 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371749,707,674 - 50,237,383 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361747,062,673 - 47,592,376 (-)NCBINCBI36hg18NCBI36
Build 341747,062,682 - 47,591,086NCBI
Celera1746,168,954 - 46,698,633 (-)NCBI
Cytogenetic Map17q21.33-q22NCBI
HuRef1745,077,023 - 45,606,524 (-)NCBIHuRef
CHM1_11749,772,091 - 50,302,474 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:8673298   PMID:9921901   PMID:11230166   PMID:11311946   PMID:12044474   PMID:12477932   PMID:12500287   PMID:12975309   PMID:15328829   PMID:15489334   PMID:15499993   PMID:16344560  
PMID:17081983   PMID:19172221   PMID:19240061   PMID:20379614   PMID:21102462   PMID:21873635   PMID:23400010   PMID:24407380   PMID:25231870   PMID:25317112   PMID:25880085   PMID:26186194  
PMID:26507551   PMID:28154140   PMID:28514442   PMID:28537244   PMID:29291617   PMID:30636076   PMID:32736539  


Genomics

Comparative Map Data
CA10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1751,630,313 - 52,160,017 (-)EnsemblGRCh38hg38GRCh38
GRCh381751,630,313 - 52,160,023 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371749,707,674 - 50,237,383 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361747,062,673 - 47,592,376 (-)NCBINCBI36hg18NCBI36
Build 341747,062,682 - 47,591,086NCBI
Celera1746,168,954 - 46,698,633 (-)NCBI
Cytogenetic Map17q21.33-q22NCBI
HuRef1745,077,023 - 45,606,524 (-)NCBIHuRef
CHM1_11749,772,091 - 50,302,474 (-)NCBICHM1_1
Car10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391192,988,807 - 93,492,577 (+)NCBIGRCm39mm39
GRCm39 Ensembl1192,988,854 - 93,492,575 (+)Ensembl
GRCm381193,096,805 - 93,601,751 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1193,098,028 - 93,601,749 (+)EnsemblGRCm38mm10GRCm38
MGSCv371192,960,604 - 93,463,065 (+)NCBIGRCm37mm9NCBIm37
MGSCv361192,914,500 - 93,417,363 (+)NCBImm8
Celera11102,697,483 - 103,221,769 (+)NCBICelera
Cytogenetic Map11DNCBI
Car10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21078,055,875 - 78,556,490 (+)NCBI
Rnor_6.0 Ensembl1080,790,168 - 81,296,363 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01080,790,151 - 81,297,621 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01080,633,872 - 81,133,347 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41081,756,486 - 82,238,335 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1076,855,697 - 77,353,776 (+)NCBICelera
Cytogenetic Map10q26NCBI
Ca10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554519,877,223 - 10,362,414 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554519,877,768 - 10,362,363 (+)NCBIChiLan1.0ChiLan1.0
CA10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11750,587,548 - 51,126,498 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1750,587,548 - 51,124,265 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01745,718,219 - 46,257,295 (-)NCBIMhudiblu_PPA_v0panPan3
CA10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1927,382,508 - 27,863,806 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl927,383,588 - 27,862,086 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha926,709,833 - 27,197,336 (-)NCBI
ROS_Cfam_1.0928,176,480 - 28,657,670 (-)NCBI
UMICH_Zoey_3.1926,942,042 - 27,417,434 (-)NCBI
UNSW_CanFamBas_1.0927,201,860 - 27,676,691 (-)NCBI
UU_Cfam_GSD_1.0927,332,548 - 27,807,012 (-)NCBI
Ca10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560226,798,112 - 27,274,308 (-)NCBI
SpeTri2.0NW_0049364909,800,533 - 10,277,034 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CA10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1227,957,732 - 28,617,585 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11227,979,321 - 28,619,022 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21228,270,028 - 28,295,145 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CA10
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11641,169,232 - 41,720,008 (+)NCBI
Ca10
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247957,284,520 - 7,792,200 (-)NCBI

Position Markers
D17S809  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371749,917,730 - 49,917,974UniSTSGRCh37
GRCh371749,917,684 - 49,917,951UniSTSGRCh37
Build 361747,272,729 - 47,272,973RGDNCBI36
Celera1746,378,994 - 46,379,234RGD
Celera1746,378,948 - 46,379,211UniSTS
Cytogenetic Map17q21.33UniSTS
HuRef1745,287,015 - 45,287,276UniSTS
HuRef1745,287,061 - 45,287,299UniSTS
Marshfield Genetic Map1774.45RGD
Genethon Genetic Map1774.5UniSTS
TNG Radiation Hybrid Map1723102.0UniSTS
Stanford-G3 RH Map172238.0UniSTS
GeneMap99-GB4 RH Map17349.05UniSTS
Whitehead-RH Map17399.2UniSTS
Whitehead-YAC Contig Map17 UniSTS
GeneMap99-G3 RH Map172739.0UniSTS
D17S956  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371749,914,334 - 49,914,497UniSTSGRCh37
Build 361747,269,333 - 47,269,496RGDNCBI36
Celera1746,375,599 - 46,375,762RGD
Cytogenetic Map17q21.33UniSTS
HuRef1745,283,664 - 45,283,829UniSTS
Marshfield Genetic Map1773.62RGD
Marshfield Genetic Map1773.62UniSTS
Genethon Genetic Map1774.5UniSTS
deCODE Assembly Map1778.92UniSTS
Whitehead-RH Map17397.4UniSTS
Whitehead-YAC Contig Map17 UniSTS
D17S1820  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371749,784,861 - 49,785,120UniSTSGRCh37
Build 361747,139,860 - 47,140,119RGDNCBI36
Celera1746,246,157 - 46,246,420RGD
Cytogenetic Map17q21.33UniSTS
HuRef1745,154,219 - 45,154,496UniSTS
Marshfield Genetic Map1771.93RGD
Marshfield Genetic Map1771.93UniSTS
Genethon Genetic Map1772.7UniSTS
TNG Radiation Hybrid Map1723170.0UniSTS
deCODE Assembly Map1778.76UniSTS
D17S941  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371749,836,674 - 49,836,947UniSTSGRCh37
Build 361747,191,673 - 47,191,946RGDNCBI36
Celera1746,297,973 - 46,298,240RGD
Cytogenetic Map17q21.33UniSTS
HuRef1745,206,064 - 45,206,331UniSTS
Marshfield Genetic Map1771.93RGD
Marshfield Genetic Map1771.93UniSTS
Genethon Genetic Map1772.7UniSTS
TNG Radiation Hybrid Map1723161.0UniSTS
deCODE Assembly Map1778.76UniSTS
GeneMap99-GB4 RH Map17349.15UniSTS
Whitehead-YAC Contig Map17 UniSTS
STS-N26826  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371749,707,836 - 49,708,020UniSTSGRCh37
Build 361747,062,835 - 47,063,019RGDNCBI36
Celera1746,169,116 - 46,169,300RGD
Cytogenetic Map17q21.33UniSTS
HuRef1745,077,185 - 45,077,369UniSTS
GeneMap99-GB4 RH Map17349.15UniSTS
RH11759  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371749,708,388 - 49,708,489UniSTSGRCh37
Build 361747,063,387 - 47,063,488RGDNCBI36
Celera1746,169,668 - 46,169,769RGD
Cytogenetic Map17q21.33UniSTS
HuRef1745,077,737 - 45,077,838UniSTS
GeneMap99-GB4 RH Map17349.15UniSTS
A002U30  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371749,708,152 - 49,708,323UniSTSGRCh37
Build 361747,063,151 - 47,063,322RGDNCBI36
Celera1746,169,432 - 46,169,603RGD
Cytogenetic Map17q21.33UniSTS
HuRef1745,077,501 - 45,077,672UniSTS
GeneMap99-GB4 RH Map17349.05UniSTS
WI-22496  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371749,707,774 - 49,708,023UniSTSGRCh37
Build 361747,062,773 - 47,063,022RGDNCBI36
Celera1746,169,054 - 46,169,303RGD
Cytogenetic Map17q21.33UniSTS
HuRef1745,077,123 - 45,077,372UniSTS
GeneMap99-GB4 RH Map17349.05UniSTS
Whitehead-RH Map17397.1UniSTS
RH91156  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371749,708,215 - 49,708,337UniSTSGRCh37
Build 361747,063,214 - 47,063,336RGDNCBI36
Celera1746,169,495 - 46,169,617RGD
Cytogenetic Map17q21.33UniSTS
HuRef1745,077,564 - 45,077,686UniSTS
GeneMap99-GB4 RH Map17352.18UniSTS
SHGC-62998  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371749,750,443 - 49,750,663UniSTSGRCh37
Build 361747,105,442 - 47,105,662RGDNCBI36
Celera1746,211,741 - 46,211,961RGD
Cytogenetic Map17q21.33UniSTS
HuRef1745,119,805 - 45,120,025UniSTS
SHGC-81490  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371750,224,885 - 50,225,213UniSTSGRCh37
Build 361747,579,884 - 47,580,212RGDNCBI36
Celera1746,686,140 - 46,686,468RGD
Cytogenetic Map17q21.33UniSTS
HuRef1745,594,032 - 45,594,360UniSTS
TNG Radiation Hybrid Map1723703.0UniSTS
RH124024  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371749,791,939 - 49,792,220UniSTSGRCh37
Build 361747,146,938 - 47,147,219RGDNCBI36
Celera1746,253,238 - 46,253,519RGD
Cytogenetic Map17q21.33UniSTS
HuRef1745,161,314 - 45,161,595UniSTS
TNG Radiation Hybrid Map1723170.0UniSTS
G60320  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371749,914,285 - 49,914,506UniSTSGRCh37
Build 361747,269,284 - 47,269,505RGDNCBI36
Celera1746,375,550 - 46,375,771RGD
Cytogenetic Map17q21.33UniSTS
HuRef1745,283,615 - 45,283,838UniSTS
TNG Radiation Hybrid Map1723109.0UniSTS
TNG Radiation Hybrid Map188128.0UniSTS
SHGC-133050  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371749,750,418 - 49,750,692UniSTSGRCh37
Build 361747,105,417 - 47,105,691RGDNCBI36
Celera1746,211,716 - 46,211,990RGD
Cytogenetic Map17q21.33UniSTS
HuRef1745,119,780 - 45,120,054UniSTS
TNG Radiation Hybrid Map1723186.0UniSTS
D17S2122  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371750,226,373 - 50,226,524UniSTSGRCh37
Build 361747,581,372 - 47,581,523RGDNCBI36
Celera1746,687,628 - 46,687,779RGD
Cytogenetic Map17q21.33UniSTS
HuRef1745,595,520 - 45,595,671UniSTS
Stanford-G3 RH Map172255.0UniSTS
D17S1388E  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371749,708,390 - 49,708,520UniSTSGRCh37
Build 361747,063,389 - 47,063,519RGDNCBI36
Celera1746,169,670 - 46,169,800RGD
Cytogenetic Map17q21.33UniSTS
HuRef1745,077,739 - 45,077,869UniSTS
GeneMap99-GB4 RH Map17349.15UniSTS
A008O45  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371749,958,813 - 49,958,960UniSTSGRCh37
Build 361747,313,812 - 47,313,959RGDNCBI36
Celera1746,420,068 - 46,420,215RGD
Cytogenetic Map17q21.33UniSTS
HuRef1745,328,117 - 45,328,264UniSTS
GeneMap99-GB4 RH Map17349.15UniSTS
CA10_4487  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371749,707,503 - 49,708,296UniSTSGRCh37
Build 361747,062,502 - 47,063,295RGDNCBI36
Celera1746,168,783 - 46,169,576RGD
HuRef1745,076,852 - 45,077,645UniSTS
D17S809  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map17q21.33UniSTS
Marshfield Genetic Map1774.45UniSTS
Genethon Genetic Map1774.5UniSTS
GeneMap99-GB4 RH Map17349.05UniSTS
Whitehead-RH Map17399.2UniSTS
Whitehead-YAC Contig Map17 UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:4701
Count of miRNA genes:1029
Interacting mature miRNAs:1283
Transcripts:ENST00000285273, ENST00000340813, ENST00000442502, ENST00000451037, ENST00000570565, ENST00000571371, ENST00000571918, ENST00000573294, ENST00000575097, ENST00000575181
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component
High
Medium 4 3 2 1528 46 44 22
Low 244 23 324 62 35 5 129 6 1490 163 508 64 59 1 7 28 1
Below cutoff 1800 1721 915 274 778 173 2669 1514 469 52 610 1094 102 778 1773 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001082533 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001082534 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_020178 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017024878 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB001597 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB036836 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC002090 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC004108 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC005883 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC006083 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC016473 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC092713 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF064854 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF288385 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK294652 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK313001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL161812 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AW135066 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY358509 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC020577 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC029865 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC047456 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC068462 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471109 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR749607 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA110822 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA128892 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA518921 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GQ901003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KC877658 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KF456288 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KF456289 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KF456292 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KF511488 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000285273   ⟹   ENSP00000285273
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1751,630,769 - 52,159,801 (-)Ensembl
RefSeq Acc Id: ENST00000442502   ⟹   ENSP00000390666
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1751,630,313 - 52,160,017 (-)Ensembl
RefSeq Acc Id: ENST00000451037   ⟹   ENSP00000405388
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1751,630,320 - 52,158,714 (-)Ensembl
RefSeq Acc Id: ENST00000570565   ⟹   ENSP00000459619
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1751,630,313 - 52,160,002 (-)Ensembl
RefSeq Acc Id: ENST00000571371   ⟹   ENSP00000461908
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1751,630,320 - 52,158,063 (-)Ensembl
RefSeq Acc Id: ENST00000571918
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1751,635,855 - 51,748,544 (-)Ensembl
RefSeq Acc Id: ENST00000573294
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1751,931,064 - 52,158,063 (-)Ensembl
RefSeq Acc Id: ENST00000575097   ⟹   ENSP00000458145
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1751,661,593 - 51,747,788 (-)Ensembl
RefSeq Acc Id: ENST00000575181   ⟹   ENSP00000460238
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1751,633,612 - 52,159,983 (-)Ensembl
RefSeq Acc Id: NM_001082533   ⟹   NP_001076002
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381751,630,313 - 52,159,801 (-)NCBI
GRCh371749,707,674 - 50,237,377 (-)ENTREZGENE
Build 361747,062,673 - 47,592,160 (-)NCBI Archive
HuRef1745,077,023 - 45,606,524 (-)ENTREZGENE
CHM1_11749,772,091 - 50,302,258 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001082534   ⟹   NP_001076003
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381751,630,320 - 52,160,023 (-)NCBI
GRCh371749,707,674 - 50,237,377 (-)ENTREZGENE
Build 361747,062,673 - 47,592,376 (-)NCBI Archive
HuRef1745,077,023 - 45,606,524 (-)ENTREZGENE
CHM1_11749,772,091 - 50,302,474 (-)NCBI
Sequence:
RefSeq Acc Id: NM_020178   ⟹   NP_064563
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381751,630,320 - 52,158,714 (-)NCBI
GRCh371749,707,674 - 50,237,377 (-)ENTREZGENE
Build 361747,062,673 - 47,591,131 (-)NCBI Archive
HuRef1745,077,023 - 45,606,524 (-)ENTREZGENE
CHM1_11749,772,091 - 50,301,228 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017024878   ⟹   XP_016880367
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381751,630,768 - 51,748,545 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_001076003   ⟸   NM_001082534
- Peptide Label: precursor
- UniProtKB: Q9NS85 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001076002   ⟸   NM_001082533
- Peptide Label: precursor
- UniProtKB: Q9NS85 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_064563   ⟸   NM_020178
- Peptide Label: precursor
- UniProtKB: Q9NS85 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_016880367   ⟸   XM_017024878
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSP00000405388   ⟸   ENST00000451037
RefSeq Acc Id: ENSP00000459619   ⟸   ENST00000570565
RefSeq Acc Id: ENSP00000461908   ⟸   ENST00000571371
RefSeq Acc Id: ENSP00000390666   ⟸   ENST00000442502
RefSeq Acc Id: ENSP00000285273   ⟸   ENST00000285273
RefSeq Acc Id: ENSP00000460238   ⟸   ENST00000575181
RefSeq Acc Id: ENSP00000458145   ⟸   ENST00000575097
Protein Domains
Alpha-carbonic anhydrase

Promoters
RGD ID:7235703
Promoter ID:EPDNEW_H23598
Type:initiation region
Name:CA10_1
Description:carbonic anhydrase 10
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H23599  EPDNEW_H23600  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381752,158,132 - 52,158,192EPDNEW
RGD ID:7235707
Promoter ID:EPDNEW_H23599
Type:initiation region
Name:CA10_2
Description:carbonic anhydrase 10
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H23598  EPDNEW_H23600  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381752,158,685 - 52,158,745EPDNEW
RGD ID:7235709
Promoter ID:EPDNEW_H23600
Type:initiation region
Name:CA10_3
Description:carbonic anhydrase 10
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H23598  EPDNEW_H23599  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381752,160,008 - 52,160,068EPDNEW

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 17q21.33-24.2(chr17:36449220-68170214)x3 copy number gain See cases [RCV000050957] Chr17:36449220..68170214 [GRCh38]
Chr17:48563237..65936105 [GRCh37]
Chr17:45918236..63677950 [NCBI36]
Chr17:17q21.33-24.2
pathogenic
GRCh38/hg38 17q23.2-25.3(chr17:36449220-83086677)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052483]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052483]|See cases [RCV000052483] Chr17:36449220..83086677 [GRCh38]
Chr17:58617905..81044553 [GRCh37]
Chr17:55972687..78637842 [NCBI36]
Chr17:17q23.2-25.3
pathogenic
GRCh38/hg38 17q21.32-22(chr17:49137864-52147810)x1 copy number loss See cases [RCV000053432] Chr17:49137864..52147810 [GRCh38]
Chr17:47215226..50225170 [GRCh37]
Chr17:44570225..47580169 [NCBI36]
Chr17:17q21.32-22
pathogenic
GRCh38/hg38 17q21.33-22(chr17:49974533-56807609)x1 copy number loss See cases [RCV000053433] Chr17:49974533..56807609 [GRCh38]
Chr17:48051897..54884970 [GRCh37]
Chr17:45406896..52239969 [NCBI36]
Chr17:17q21.33-22
pathogenic
NM_001082533.1(CA10):c.228G>A (p.Met76Ile) single nucleotide variant Malignant melanoma [RCV000071570] Chr17:51931041 [GRCh38]
Chr17:50008401 [GRCh37]
Chr17:47363400 [NCBI36]
Chr17:17q21.33
not provided
NM_001082533.1(CA10):c.85C>T (p.His29Tyr) single nucleotide variant Malignant melanoma [RCV000063250] Chr17:52072370 [GRCh38]
Chr17:50149730 [GRCh37]
Chr17:47504729 [NCBI36]
Chr17:17q21.33
not provided
NM_001082533.1(CA10):c.634+4004G>A single nucleotide variant Lung cancer [RCV000100498] Chr17:51645178 [GRCh38]
Chr17:49722539 [GRCh37]
Chr17:17q21.33
uncertain significance
NM_001082533.1(CA10):c.280-31204C>T single nucleotide variant Lung cancer [RCV000100499] Chr17:51779022 [GRCh38]
Chr17:49856382 [GRCh37]
Chr17:17q21.33
uncertain significance
NM_001082533.1(CA10):c.279+85225G>A single nucleotide variant Lung cancer [RCV000100500] Chr17:51845765 [GRCh38]
Chr17:49923125 [GRCh37]
Chr17:17q21.33
uncertain significance
NM_001082533.1(CA10):c.279+19026T>C single nucleotide variant Lung cancer [RCV000100501] Chr17:51911964 [GRCh38]
Chr17:49989324 [GRCh37]
Chr17:17q21.33
uncertain significance
NM_001082533.1(CA10):c.279+4949T>A single nucleotide variant Lung cancer [RCV000100502] Chr17:51926041 [GRCh38]
Chr17:50003401 [GRCh37]
Chr17:17q21.33
uncertain significance
NM_001082533.1(CA10):c.279+2172T>C single nucleotide variant Lung cancer [RCV000100503] Chr17:51928818 [GRCh38]
Chr17:50006178 [GRCh37]
Chr17:17q21.33
uncertain significance
NM_001082533.1(CA10):c.136+55731G>A single nucleotide variant Lung cancer [RCV000100504] Chr17:52016588 [GRCh38]
Chr17:50093948 [GRCh37]
Chr17:17q21.33
uncertain significance
NM_001082533.1(CA10):c.62-36766G>T single nucleotide variant Lung cancer [RCV000100505] Chr17:52109159 [GRCh38]
Chr17:50186519 [GRCh37]
Chr17:17q22
uncertain significance
GRCh38/hg38 17q23.1-25.1(chr17:36449220-75053130)x3 copy number gain See cases [RCV000137437] Chr17:36449220..75053130 [GRCh38]
Chr17:57595736..73049225 [GRCh37]
Chr17:54950518..70560820 [NCBI36]
Chr17:17q23.1-25.1
pathogenic
GRCh38/hg38 17q21.33-22(chr17:51990459-52697115)x3 copy number gain See cases [RCV000134182] Chr17:51990459..52697115 [GRCh38]
Chr17:50067819..50774475 [GRCh37]
Chr17:47422818..48129474 [NCBI36]
Chr17:17q21.33-22
uncertain significance
GRCh37/hg19 17q21.33-23.2(chr17:49076980-58740945)x3 copy number gain See cases [RCV000448805] Chr17:49076980..58740945 [GRCh37]
Chr17:17q21.33-23.2
pathogenic
GRCh37/hg19 17q21.31-25.3(chr17:42580684-81085615)x3 copy number gain See cases [RCV000447823] Chr17:42580684..81085615 [GRCh37]
Chr17:17q21.31-25.3
pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:526-81041938) copy number gain See cases [RCV000511439] Chr17:526..81041938 [GRCh37]
Chr17:17p13.3-q25.3
pathogenic
GRCh37/hg19 17q21.33-22(chr17:49705772-50359611)x3 copy number gain See cases [RCV000511137] Chr17:49705772..50359611 [GRCh37]
Chr17:17q21.33-22
uncertain significance
GRCh37/hg19 17p13.3-q25.3(chr17:526-81041938)x3 copy number gain See cases [RCV000512441] Chr17:526..81041938 [GRCh37]
Chr17:17p13.3-q25.3
pathogenic
GRCh37/hg19 17q21.32-22(chr17:46481089-51396368)x1 copy number loss not provided [RCV000513510] Chr17:46481089..51396368 [GRCh37]
Chr17:17q21.32-22
likely pathogenic
GRCh37/hg19 17q21.33(chr17:49901770-49966972)x1 copy number loss not provided [RCV000683941] Chr17:49901770..49966972 [GRCh37]
Chr17:17q21.33
likely benign
GRCh37/hg19 17p13.3-q25.3(chr17:8547-81060040)x3 copy number gain not provided [RCV000739324] Chr17:8547..81060040 [GRCh37]
Chr17:17p13.3-q25.3
pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:7214-81058310)x3 copy number gain not provided [RCV000739320] Chr17:7214..81058310 [GRCh37]
Chr17:17p13.3-q25.3
pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:12344-81057996)x3 copy number gain not provided [RCV000739325] Chr17:12344..81057996 [GRCh37]
Chr17:17p13.3-q25.3
pathogenic
GRCh37/hg19 17q21.33(chr17:49898149-49899308)x1 copy number loss not provided [RCV000739619] Chr17:49898149..49899308 [GRCh37]
Chr17:17q21.33
benign
GRCh37/hg19 17q21.33-22(chr17:50198539-51590562)x1 copy number loss not provided [RCV001259897] Chr17:50198539..51590562 [GRCh37]
Chr17:17q21.33-22
uncertain significance

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:1369 AgrOrtholog
COSMIC CA10 COSMIC
Ensembl Genes ENSG00000154975 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000285273 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000390666 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000405388 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000458145 UniProtKB/TrEMBL
  ENSP00000459619 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000460238 UniProtKB/TrEMBL
  ENSP00000461908 UniProtKB/TrEMBL
Ensembl Transcript ENST00000285273 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000442502 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000451037 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000570565 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000571371 UniProtKB/TrEMBL
  ENST00000575097 UniProtKB/TrEMBL
  ENST00000575181 UniProtKB/TrEMBL
Gene3D-CATH 3.10.200.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000154975 GTEx
HGNC ID HGNC:1369 ENTREZGENE
Human Proteome Map CA10 Human Proteome Map
InterPro alpha_CARP_X/XI UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CA10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CA_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CA_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Carbonic_anhydrase_a-class UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:56934 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 56934 ENTREZGENE
OMIM 604642 OMIM
PANTHER PTHR18952 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR18952:SF91 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Carb_anhydrase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA25985 PharmGKB
PROSITE ALPHA_CA_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART Carb_anhydrase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF51069 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A384MTY8_HUMAN UniProtKB/TrEMBL
  A0PJH9_HUMAN UniProtKB/TrEMBL
  CAH10_HUMAN UniProtKB/Swiss-Prot
  I3L0J7_HUMAN UniProtKB/TrEMBL
  I3L375_HUMAN UniProtKB/TrEMBL
  I3NI54_HUMAN UniProtKB/TrEMBL
  Q9NS85 ENTREZGENE
UniProt Secondary B2R7J0 UniProtKB/Swiss-Prot
  B4DGL6 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-28 CA10  carbonic anhydrase 10  CA10  carbonic anhydrase X  Symbol and/or name change 5135510 APPROVED