POPDC2 (popeye domain containing 2) - Rat Genome Database

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Gene: POPDC2 (popeye domain containing 2) Homo sapiens
Analyze
Symbol: POPDC2
Name: popeye domain containing 2
RGD ID: 1352577
HGNC Page HGNC:17648
Description: Predicted to enable cAMP binding activity. Predicted to be involved in several processes, including regulation of heart rate; skeletal muscle tissue development; and striated muscle cell differentiation. Predicted to act upstream of or within sinoatrial node cell development. Located in sarcolemma.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: POP2; popeye domain-containing protein 2; popeye protein 2
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383119,642,056 - 119,660,883 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3119,636,457 - 119,665,324 (-)EnsemblGRCh38hg38GRCh38
GRCh373119,360,903 - 119,379,436 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363120,843,596 - 120,862,094 (-)NCBINCBI36Build 36hg18NCBI36
Build 343120,843,597 - 120,862,094NCBI
Celera3117,769,457 - 117,787,954 (-)NCBICelera
Cytogenetic Map3q13.33NCBI
HuRef3116,736,572 - 116,755,066 (-)NCBIHuRef
CHM1_13119,324,408 - 119,342,901 (-)NCBICHM1_1
T2T-CHM13v2.03122,361,759 - 122,380,618 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
membrane  (IEA,NAS)
plasma membrane  (IEA)
sarcolemma  (IBA,IDA,IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Isolation and characterization of the novel popeye gene family expressed in skeletal muscle and heart. Andree B, etal., Dev Biol 2000 Jul 15;223(2):371-82.
2. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8125298   PMID:12477932   PMID:15489334   PMID:17207965   PMID:21873635   PMID:26186194   PMID:26642364   PMID:28514442   PMID:28939104   PMID:32535041   PMID:33261556   PMID:33961781  
PMID:36624536  


Genomics

Comparative Map Data
POPDC2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383119,642,056 - 119,660,883 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3119,636,457 - 119,665,324 (-)EnsemblGRCh38hg38GRCh38
GRCh373119,360,903 - 119,379,436 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363120,843,596 - 120,862,094 (-)NCBINCBI36Build 36hg18NCBI36
Build 343120,843,597 - 120,862,094NCBI
Celera3117,769,457 - 117,787,954 (-)NCBICelera
Cytogenetic Map3q13.33NCBI
HuRef3116,736,572 - 116,755,066 (-)NCBIHuRef
CHM1_13119,324,408 - 119,342,901 (-)NCBICHM1_1
T2T-CHM13v2.03122,361,759 - 122,380,618 (-)NCBIT2T-CHM13v2.0
Popdc2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391638,182,523 - 38,198,578 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1638,182,571 - 38,198,578 (+)EnsemblGRCm39 Ensembl
GRCm381638,362,161 - 38,378,216 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1638,362,209 - 38,378,216 (+)EnsemblGRCm38mm10GRCm38
MGSCv371638,362,259 - 38,378,302 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361638,281,484 - 38,297,455 (+)NCBIMGSCv36mm8
Celera1638,772,441 - 38,788,493 (+)NCBICelera
Cytogenetic Map16B3NCBI
cM Map1626.79NCBI
Popdc2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81175,850,068 - 75,897,094 (-)NCBIGRCr8
mRatBN7.21162,351,843 - 62,398,688 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1162,374,759 - 62,390,756 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1171,187,283 - 71,203,279 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01163,849,530 - 63,865,526 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01162,899,864 - 62,915,862 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01164,915,041 - 64,954,704 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1164,936,692 - 64,952,687 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01167,129,306 - 67,151,642 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41164,154,286 - 64,170,282 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11164,211,875 - 64,227,871 (-)NCBI
Celera1161,876,220 - 61,892,242 (-)NCBICelera
Cytogenetic Map11q21NCBI
Popdc2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542719,345,226 - 19,367,759 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542719,347,880 - 19,367,759 (-)NCBIChiLan1.0ChiLan1.0
POPDC2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22117,616,288 - 117,634,891 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13117,621,068 - 117,639,660 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03116,761,474 - 116,780,369 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13123,673,815 - 123,692,684 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3123,673,815 - 123,692,684 (-)Ensemblpanpan1.1panPan2
POPDC2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13323,275,666 - 23,295,413 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3323,276,455 - 23,295,088 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3323,306,245 - 23,325,293 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03323,513,597 - 23,533,028 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3323,514,929 - 23,548,542 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13323,316,273 - 23,335,538 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03323,352,389 - 23,370,898 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03323,921,853 - 23,941,107 (-)NCBIUU_Cfam_GSD_1.0
Popdc2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602130,939,491 - 130,958,507 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365366,560,329 - 6,582,331 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365366,562,583 - 6,582,407 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
POPDC2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13140,601,515 - 140,620,789 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113140,601,522 - 140,621,928 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213149,932,130 - 149,951,356 (+)NCBISscrofa10.2Sscrofa10.2susScr3
POPDC2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12261,160,174 - 61,178,838 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2261,160,413 - 61,178,414 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041105,133,456 - 105,151,992 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Popdc2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473128,493,230 - 28,523,157 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473128,490,489 - 28,521,611 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in POPDC2
19 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 3q11.1-21.1(chr3:93886671-123216683)x1 copy number loss See cases [RCV000051543] Chr3:93886671..123216683 [GRCh38]
Chr3:93605515..122935530 [GRCh37]
Chr3:95088205..124418220 [NCBI36]
Chr3:3q11.1-21.1		 pathogenic
GRCh38/hg38 3q13.32-21.2(chr3:119117166-125920734)x1 copy number loss See cases [RCV000051546] Chr3:119117166..125920734 [GRCh38]
Chr3:118836013..125639577 [GRCh37]
Chr3:120318703..127122267 [NCBI36]
Chr3:3q13.32-21.2		 pathogenic
GRCh38/hg38 3q13.11-29(chr3:103426882-198110178)x3 copy number gain See cases [RCV000134948] Chr3:103426882..198110178 [GRCh38]
Chr3:103145726..197837049 [GRCh37]
Chr3:104628416..199321446 [NCBI36]
Chr3:3q13.11-29		 pathogenic
GRCh38/hg38 3q13.32-13.33(chr3:117844958-120797026)x4 copy number gain See cases [RCV000135591] Chr3:117844958..120797026 [GRCh38]
Chr3:117563805..120515873 [GRCh37]
Chr3:119046495..121998563 [NCBI36]
Chr3:3q13.32-13.33		 uncertain significance
GRCh38/hg38 3q13.31-21.1(chr3:115019074-122513398)x1 copy number loss See cases [RCV000135961] Chr3:115019074..122513398 [GRCh38]
Chr3:114737921..122232245 [GRCh37]
Chr3:116220611..123714935 [NCBI36]
Chr3:3q13.31-21.1		 pathogenic
GRCh38/hg38 3q13.2-21.3(chr3:112620977-128734134)x1 copy number loss See cases [RCV000139033] Chr3:112620977..128734134 [GRCh38]
Chr3:112339824..128452977 [GRCh37]
Chr3:113822514..129935667 [NCBI36]
Chr3:3q13.2-21.3		 pathogenic
GRCh38/hg38 3q13.31-21.2(chr3:114122562-124532374)x1 copy number loss See cases [RCV000142009] Chr3:114122562..124532374 [GRCh38]
Chr3:113841409..124251221 [GRCh37]
Chr3:115324099..125733911 [NCBI36]
Chr3:3q13.31-21.2		 pathogenic
GRCh38/hg38 3q11.1-24(chr3:93800620-145695381)x3 copy number gain See cases [RCV000142340] Chr3:93800620..145695381 [GRCh38]
Chr3:93519464..145413168 [GRCh37]
Chr3:95002154..146895858 [NCBI36]
Chr3:3q11.1-24		 pathogenic
GRCh38/hg38 3q13.32-13.33(chr3:117844958-120826621)x4 copy number gain See cases [RCV000142877] Chr3:117844958..120826621 [GRCh38]
Chr3:117563805..120545468 [GRCh37]
Chr3:119046495..122028158 [NCBI36]
Chr3:3q13.32-13.33		 uncertain significance
GRCh38/hg38 3q13.2-13.33(chr3:112520553-120031022)x1 copy number loss See cases [RCV000142725] Chr3:112520553..120031022 [GRCh38]
Chr3:112239400..119749869 [GRCh37]
Chr3:113722090..121232559 [NCBI36]
Chr3:3q13.2-13.33		 pathogenic
GRCh38/hg38 3q13.32-21.3(chr3:118673898-126540730)x1 copy number loss See cases [RCV000143695] Chr3:118673898..126540730 [GRCh38]
Chr3:118392745..126259573 [GRCh37]
Chr3:119875435..127742263 [NCBI36]
Chr3:3q13.32-21.3		 pathogenic
GRCh37/hg19 3q13.33(chr3:119188677-119500810)x3 copy number gain See cases [RCV000240551] Chr3:119188677..119500810 [GRCh37]
Chr3:3q13.33		 uncertain significance
GRCh37/hg19 3q13.33(chr3:119188677-119500751)x3 copy number gain See cases [RCV000445965] Chr3:119188677..119500751 [GRCh37]
Chr3:3q13.33		 uncertain significance
GRCh37/hg19 3p26.3-q29(chr3:61892-197851986) copy number gain See cases [RCV000512358] Chr3:61892..197851986 [GRCh37]
Chr3:3p26.3-q29		 pathogenic
GRCh37/hg19 3q13.31-21.1(chr3:115518341-122129283)x1 copy number loss not provided [RCV000682298] Chr3:115518341..122129283 [GRCh37]
Chr3:3q13.31-21.1		 pathogenic
GRCh37/hg19 3p26.3-q29(chr3:61495-197838262)x3 copy number gain not provided [RCV000742138] Chr3:61495..197838262 [GRCh37]
Chr3:3p26.3-q29		 pathogenic
GRCh37/hg19 3q13.31-26.31(chr3:116620308-172042292)x3 copy number gain not provided [RCV002472621] Chr3:116620308..172042292 [GRCh37]
Chr3:3q13.31-26.31		 pathogenic
GRCh37/hg19 3q13.31-13.33(chr3:116109191-120328013)x1 copy number loss not provided [RCV002473909] Chr3:116109191..120328013 [GRCh37]
Chr3:3q13.31-13.33		 uncertain significance
GRCh37/hg19 3q13.33(chr3:119354755-119773920) copy number gain not specified [RCV002053370] Chr3:119354755..119773920 [GRCh37]
Chr3:3q13.33		 uncertain significance
NM_001369919.2(POPDC2):c.430C>A (p.Gln144Lys) single nucleotide variant Inborn genetic diseases [RCV003294831] Chr3:119659994 [GRCh38]
Chr3:119378841 [GRCh37]
Chr3:3q13.33		 uncertain significance
GRCh37/hg19 3p26.3-q29(chr3:61892-197851986)x3 copy number gain See cases [RCV000511055] Chr3:61892..197851986 [GRCh37]
Chr3:3p26.3-q29		 pathogenic
GRCh37/hg19 3p26.3-q29(chr3:60174-197948027)x3 copy number gain not provided [RCV000742133] Chr3:60174..197948027 [GRCh37]
Chr3:3p26.3-q29		 pathogenic
NM_001369919.2(POPDC2):c.83C>A (p.Ala28Asp) single nucleotide variant Inborn genetic diseases [RCV003277152] Chr3:119660341 [GRCh38]
Chr3:119379188 [GRCh37]
Chr3:3q13.33		 uncertain significance
NM_001369919.2(POPDC2):c.271C>G (p.Gln91Glu) single nucleotide variant Inborn genetic diseases [RCV002865227] Chr3:119660153 [GRCh38]
Chr3:119379000 [GRCh37]
Chr3:3q13.33		 uncertain significance
NM_001369919.2(POPDC2):c.680G>A (p.Arg227Gln) single nucleotide variant Inborn genetic diseases [RCV002947093] Chr3:119648589 [GRCh38]
Chr3:119367436 [GRCh37]
Chr3:3q13.33		 uncertain significance
NM_001369919.2(POPDC2):c.335A>G (p.Tyr112Cys) single nucleotide variant Inborn genetic diseases [RCV002704880] Chr3:119660089 [GRCh38]
Chr3:119378936 [GRCh37]
Chr3:3q13.33		 uncertain significance
NM_001369919.2(POPDC2):c.197T>C (p.Leu66Pro) single nucleotide variant Inborn genetic diseases [RCV002977501] Chr3:119660227 [GRCh38]
Chr3:119379074 [GRCh37]
Chr3:3q13.33		 uncertain significance
NM_001369919.2(POPDC2):c.496C>T (p.Arg166Cys) single nucleotide variant Inborn genetic diseases [RCV002951505] Chr3:119654609 [GRCh38]
Chr3:119373456 [GRCh37]
Chr3:3q13.33		 uncertain significance
NM_001369919.2(POPDC2):c.95T>C (p.Leu32Pro) single nucleotide variant Inborn genetic diseases [RCV002764321] Chr3:119660329 [GRCh38]
Chr3:119379176 [GRCh37]
Chr3:3q13.33		 uncertain significance
NM_001369919.2(POPDC2):c.44G>T (p.Gly15Val) single nucleotide variant Inborn genetic diseases [RCV003004555] Chr3:119660380 [GRCh38]
Chr3:119379227 [GRCh37]
Chr3:3q13.33		 uncertain significance
NM_001369919.2(POPDC2):c.859G>A (p.Glu287Lys) single nucleotide variant Inborn genetic diseases [RCV002708815] Chr3:119648410 [GRCh38]
Chr3:119367257 [GRCh37]
Chr3:3q13.33		 uncertain significance
NM_001369919.2(POPDC2):c.405G>T (p.Glu135Asp) single nucleotide variant Inborn genetic diseases [RCV002956748] Chr3:119660019 [GRCh38]
Chr3:119378866 [GRCh37]
Chr3:3q13.33		 uncertain significance
NM_001369919.2(POPDC2):c.598C>A (p.Gln200Lys) single nucleotide variant Inborn genetic diseases [RCV002652018] Chr3:119654507 [GRCh38]
Chr3:119373354 [GRCh37]
Chr3:3q13.33		 uncertain significance
NM_001369919.2(POPDC2):c.659A>C (p.His220Pro) single nucleotide variant Inborn genetic diseases [RCV002965529] Chr3:119648610 [GRCh38]
Chr3:119367457 [GRCh37]
Chr3:3q13.33		 uncertain significance
NM_001369919.2(POPDC2):c.701C>T (p.Ser234Leu) single nucleotide variant Inborn genetic diseases [RCV002673979] Chr3:119648568 [GRCh38]
Chr3:119367415 [GRCh37]
Chr3:3q13.33		 uncertain significance
NM_001369919.2(POPDC2):c.660T>G (p.His220Gln) single nucleotide variant Inborn genetic diseases [RCV002835852] Chr3:119648609 [GRCh38]
Chr3:119367456 [GRCh37]
Chr3:3q13.33		 uncertain significance
GRCh38/hg38 3q11.1-21.2(chr3:93979547-124774010)x1 copy number loss Chromosome 3q13.31 deletion syndrome [RCV003327614] Chr3:93979547..124774010 [GRCh38]
Chr3:3q11.1-21.2		 pathogenic
NM_001369919.2(POPDC2):c.580T>C (p.Ser194Pro) single nucleotide variant Inborn genetic diseases [RCV003367469] Chr3:119654525 [GRCh38]
Chr3:119373372 [GRCh37]
Chr3:3q13.33		 uncertain significance
NM_001369919.2(POPDC2):c.973C>T (p.Arg325Trp) single nucleotide variant Inborn genetic diseases [RCV003356641] Chr3:119648296 [GRCh38]
Chr3:119367143 [GRCh37]
Chr3:3q13.33		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2327
Count of miRNA genes:796
Interacting mature miRNAs:925
Transcripts:ENST00000264231, ENST00000341124, ENST00000463323, ENST00000468801, ENST00000468916, ENST00000474523, ENST00000476092, ENST00000493094, ENST00000495362, ENST00000538678
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
SHGC-149207  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh373119,361,314 - 119,361,617UniSTSGRCh37
Build 363120,844,004 - 120,844,307RGDNCBI36
Celera3117,769,863 - 117,770,166RGD
Cytogenetic Map3q13.33UniSTS
HuRef3116,736,978 - 116,737,281UniSTS
TNG Radiation Hybrid Map368110.0UniSTS
SHGC-154625  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh373119,367,736 - 119,368,021UniSTSGRCh37
Build 363120,850,426 - 120,850,711RGDNCBI36
Celera3117,776,285 - 117,776,570RGD
Cytogenetic Map3q13.33UniSTS
HuRef3116,743,405 - 116,743,690UniSTS
TNG Radiation Hybrid Map368121.0UniSTS
SHGC-77235  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh373119,360,989 - 119,361,112UniSTSGRCh37
Build 363120,843,679 - 120,843,802RGDNCBI36
Celera3117,769,538 - 117,769,661RGD
Cytogenetic Map3q13.33UniSTS
HuRef3116,736,653 - 116,736,776UniSTS
TNG Radiation Hybrid Map368110.0UniSTS
GeneMap99-GB4 RH Map3418.72UniSTS
NCBI RH Map3929.8UniSTS
SHGC-77234  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh373119,360,902 - 119,361,052UniSTSGRCh37
Build 363120,843,592 - 120,843,742RGDNCBI36
Celera3117,769,451 - 117,769,601RGD
Cytogenetic Map3q13.33UniSTS
HuRef3116,736,566 - 116,736,716UniSTS
TNG Radiation Hybrid Map368110.0UniSTS
GeneMap99-GB4 RH Map3418.72UniSTS
Whitehead-RH Map3535.4UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 1648 1450 124 12 204 2 1113 2032 31 65 463 177 11 132 979 1
Low 717 1499 1550 568 1669 417 3114 142 3545 329 939 1342 155 1072 1809 2 1
Below cutoff 73 42 49 42 76 45 125 21 133 25 53 87 8 1 3

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001308333 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001369919 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_022135 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047448703 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047448704 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054347515 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054347516 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC023494 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC073352 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF204173 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK124602 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK226022 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK314819 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK377174 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK377176 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK377177 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK377178 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK377179 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK377180 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK377181 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK377182 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK377183 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK377184 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC026911 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC044929 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BU948168 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068275 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000264231   ⟹   ENSP00000264231
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl3119,642,059 - 119,660,590 (-)Ensembl
RefSeq Acc Id: ENST00000341124   ⟹   ENSP00000340753
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl3119,642,058 - 119,660,644 (-)Ensembl
RefSeq Acc Id: ENST00000463323
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl3119,648,441 - 119,660,585 (-)Ensembl
RefSeq Acc Id: ENST00000468801   ⟹   ENSP00000420715
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl3119,642,476 - 119,660,590 (-)Ensembl
RefSeq Acc Id: ENST00000468916
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl3119,648,378 - 119,660,587 (-)Ensembl
RefSeq Acc Id: ENST00000474523
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl3119,642,059 - 119,665,324 (-)Ensembl
RefSeq Acc Id: ENST00000476092
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl3119,648,400 - 119,654,727 (-)Ensembl
RefSeq Acc Id: ENST00000493094   ⟹   ENSP00000417250
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl3119,642,056 - 119,660,589 (-)Ensembl
RefSeq Acc Id: ENST00000495362   ⟹   ENSP00000420795
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl3119,636,457 - 119,642,552 (-)Ensembl
RefSeq Acc Id: NM_001308333   ⟹   NP_001295262
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383119,642,056 - 119,660,589 (-)NCBI
CHM1_13119,324,399 - 119,342,934 (-)NCBI
T2T-CHM13v2.03122,361,759 - 122,380,289 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001369919   ⟹   NP_001356848
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383119,642,056 - 119,660,589 (-)NCBI
T2T-CHM13v2.03122,361,759 - 122,380,289 (-)NCBI
Sequence:
RefSeq Acc Id: NM_022135   ⟹   NP_071418
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383119,642,056 - 119,660,589 (-)NCBI
GRCh373119,360,899 - 119,379,437 (-)NCBI
Build 363120,843,596 - 120,862,094 (-)NCBI Archive
Celera3117,769,457 - 117,787,954 (-)RGD
HuRef3116,736,572 - 116,755,066 (-)ENTREZGENE
CHM1_13119,324,399 - 119,342,934 (-)NCBI
T2T-CHM13v2.03122,361,759 - 122,380,289 (-)NCBI
Sequence:
RefSeq Acc Id: XM_047448703   ⟹   XP_047304659
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383119,643,367 - 119,660,589 (-)NCBI
RefSeq Acc Id: XM_047448704   ⟹   XP_047304660
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383119,642,056 - 119,660,883 (-)NCBI
RefSeq Acc Id: XM_054347515   ⟹   XP_054203490
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.03122,363,070 - 122,380,289 (-)NCBI
RefSeq Acc Id: XM_054347516   ⟹   XP_054203491
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.03122,361,759 - 122,380,618 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_071418   ⟸   NM_022135
- Peptide Label: isoform 1
- UniProtKB: Q86UE7 (UniProtKB/Swiss-Prot),   Q9HBU9 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001295262   ⟸   NM_001308333
- Peptide Label: isoform 2
- UniProtKB: Q9HBU9 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001356848   ⟸   NM_001369919
- Peptide Label: isoform 3
- UniProtKB: C9J3P7 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSP00000417250   ⟸   ENST00000493094
RefSeq Acc Id: ENSP00000420715   ⟸   ENST00000468801
RefSeq Acc Id: ENSP00000420795   ⟸   ENST00000495362
RefSeq Acc Id: ENSP00000340753   ⟸   ENST00000341124
RefSeq Acc Id: ENSP00000264231   ⟸   ENST00000264231
RefSeq Acc Id: XP_047304660   ⟸   XM_047448704
- Peptide Label: isoform X2
RefSeq Acc Id: XP_047304659   ⟸   XM_047448703
- Peptide Label: isoform X1
- UniProtKB: C9J3P7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054203491   ⟸   XM_054347516
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054203490   ⟸   XM_054347515
- Peptide Label: isoform X1
- UniProtKB: C9J3P7 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9HBU9-F1-model_v2 AlphaFold Q9HBU9 1-364 view protein structure

Promoters
RGD ID:6865354
Promoter ID:EPDNEW_H5842
Type:initiation region
Name:POPDC2_1
Description:popeye domain containing 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H5843  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh383119,660,589 - 119,660,649EPDNEW
RGD ID:6801457
Promoter ID:HG_KWN:45925
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:K562,   Lymphoblastoid,   NB4
Transcripts:UC003ECY.1
Position:
Human AssemblyChrPosition (strand)Source
Build 363120,866,511 - 120,867,777 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:17648 AgrOrtholog
COSMIC POPDC2 COSMIC
Ensembl Genes ENSG00000121577 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000264231 ENTREZGENE
  ENST00000264231.7 UniProtKB/Swiss-Prot
  ENST00000341124.9 UniProtKB/TrEMBL
  ENST00000468801 ENTREZGENE
  ENST00000468801.1 UniProtKB/Swiss-Prot
  ENST00000493094 ENTREZGENE
  ENST00000493094.6 UniProtKB/TrEMBL
  ENST00000495362.1 UniProtKB/TrEMBL
GTEx ENSG00000121577 GTEx
HGNC ID HGNC:17648 ENTREZGENE
Human Proteome Map POPDC2 Human Proteome Map
InterPro cNMP-bd-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Popeye_prot UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:64091 UniProtKB/Swiss-Prot
NCBI Gene 64091 ENTREZGENE
OMIM 605823 OMIM
PANTHER POPEYE DOMAIN-CONTAINING PROTEIN 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR12101 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Popeye UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA134982197 PharmGKB
Superfamily-SCOP SSF51206 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt C9J3P7 ENTREZGENE, UniProtKB/TrEMBL
  H7C5T7_HUMAN UniProtKB/TrEMBL
  POPD2_HUMAN UniProtKB/Swiss-Prot
  Q86UE7 ENTREZGENE
  Q9HBU9 ENTREZGENE
UniProt Secondary Q86UE7 UniProtKB/Swiss-Prot