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Gene: RAP1A (RAP1A, member of RAS oncogene family) Homo sapiens
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Symbol: RAP1A
Name: RAP1A, member of RAS oncogene family
Description: Predicted to have GTPase activity; Rap guanyl-nucleotide exchange factor activity; and purine ribonucleoside binding activity. Involved in several processes, including Rap protein signal transduction; cellular response to cAMP; and regulation of neurotransmitter receptor localization to postsynaptic specialization membrane. Localizes to the glutamatergic synapse and perinuclear region of cytoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: C21KG; G-22K; GTP-binding protein smg p21A; KREV-1; KREV1; RAP1; Ras-related protein Krev-1; ras-related protein Rap-1A; RAS-related protein RAP1A; SMGP21
Orthologs:
Mus musculus (house mouse) : Rap1a (RAS-related protein 1a)  MGI  Alliance
Rattus norvegicus (Norway rat) : Rap1a (RAP1A, member of RAS oncogene family)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rap1a (RAP1A, member of RAS oncogene family)
Pan paniscus (bonobo/pygmy chimpanzee) : RAP1A (RAP1A, member of RAS oncogene family)
Canis lupus familiaris (dog) : RAP1A (RAP1A, member of RAS oncogene family)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rap1a (RAP1A, member of RAS oncogene family)
Sus scrofa (pig) : RAP1A (RAP1A, member of RAS oncogene family)
more info ...
Related Pseudogenes: RAP1AP  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381111,542,009 - 111,716,695 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371112,162,405 - 112,256,807 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361111,963,928 - 112,057,624 (+)NCBINCBI36hg18NCBI36
Build 341111,874,446 - 111,968,142NCBI
Celera1110,480,558 - 110,502,712 (+)NCBI
Cytogenetic Map1p13.2NCBI
HuRef1110,033,768 - 110,127,466 (+)NCBIHuRef
CHM1_11112,277,395 - 112,374,298 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on RAP1A
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1352228
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.