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Gene: KLC1 (kinesin light chain 1) Homo sapiens
Symbol: KLC1
Name: kinesin light chain 1
Description: Predicted to have motor activity. Predicted to be involved in axo-dendritic transport; protein localization to synapse; and stress granule disassembly. Localizes to membrane. Implicated in Alzheimer's disease and relapsing-remitting multiple sclerosis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: kinesin 2 60/70kDa; KLC; KLC 1; KNS2; KNS2A; medulloblastoma antigen MU-MB-2.50; MGC15245; RP11-73M18.7; RP11-73M18.8
Mus musculus (house mouse) : Klc1 (kinesin light chain 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Klc1 (kinesin light chain 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Klc1 (kinesin light chain 1)
Pan paniscus (bonobo/pygmy chimpanzee) : KLC1 (kinesin light chain 1)
Canis lupus familiaris (dog) : KLC1 (kinesin light chain 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Klc1 (kinesin light chain 1)
Sus scrofa (pig) : KLC1 (kinesin light chain 1)
Heterocephalus glaber (naked mole-rat) : Klc1 (kinesin light chain 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl14103,561,896 - 103,714,249 (+)EnsemblGRCh38hg38GRCh38
GRCh3814103,629,188 - 103,701,551 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3714104,095,525 - 104,167,888 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3614103,165,278 - 103,237,641 (+)NCBINCBI36hg18NCBI36
Build 3414103,165,330 - 103,247,461NCBI
Celera1484,149,802 - 84,222,132 (+)NCBI
Cytogenetic Map14q32.33NCBI
HuRef1484,274,406 - 84,346,180 (+)NCBIHuRef
CHM1_114104,033,686 - 104,106,029 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on KLC1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1352040
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.