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Gene: CHRFAM7A (CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion) Homo sapiens
Symbol: CHRFAM7A
Name: CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion
Description: Exhibits several functions, including acetylcholine binding activity; amyloid-beta binding activity; and postsynaptic neurotransmitter receptor activity. Predicted to contribute to extracellular ligand-gated ion channel activity. Involved in several processes, including negative regulation of acetylcholine-gated cation channel activity; negative regulation of tumor necrosis factor production; and regulation of protein metabolic process. Localizes to the acetylcholine-gated channel complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: alpha 7 neuronal nicotinic acetylcholine receptor-FAM7A hybrid; alpha-7 nicotinic cholinergic receptor subunit; CHRNA7; CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion; CHRNA7 (cholinergic receptor, nicotinic, alpha polypeptide 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion; CHRNA7-DR1; CHRNA7-FAM7A fusion protein; D-10; MGC120482; MGC120483; NACHRA7; Neuronal acetylcholine receptor subunit alpha-7
No known orthologs. homologs ...
Related Pseudogenes: CHRFAM7AP1   CHRFAM7AP2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381530,360,566 - 30,393,849 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371530,652,769 - 30,685,864 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361528,440,735 - 28,473,156 (-)NCBINCBI36hg18NCBI36
Build 341528,440,734 - 28,473,156NCBI
Celera158,162,865 - 8,168,796 (-)NCBI
Cytogenetic Map15q13.2NCBI
HuRef158,073,189 - 8,085,140 (-)NCBIHuRef
CHM1_11530,620,883 - 30,653,208 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on CHRFAM7A
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1351978
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.