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Gene: TLX1 (T cell leukemia homeobox 1) Homo sapiens
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Symbol: TLX1
Name: T cell leukemia homeobox 1
Description: Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in multicellular organism development and positive regulation of transcription by RNA polymerase II. Predicted to localize to the nuclear chromatin. Implicated in adult T-cell leukemia.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: homeo box 11 (T-cell lymphoma 3-associated breakpoint); Homeo box-11 (T-cell leukemia-3 associated breakpoint, homologous to Drosophila Notch); homeobox protein Hox-11; HOX11; MGC163402; proto-oncogene TCL-3; T-cell leukemia homeobox 1; T-cell leukemia homeobox protein 1; T-cell leukemia/lymphoma protein 3; TCL3
Orthologs:
Mus musculus (house mouse) : Tlx1 (T cell leukemia, homeobox 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Tlx1 (T-cell leukemia, homeobox 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tlx1 (T cell leukemia homeobox 1)
Pan paniscus (bonobo/pygmy chimpanzee) : TLX1 (T cell leukemia homeobox 1)
Canis lupus familiaris (dog) : TLX1 (T cell leukemia homeobox 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tlx1 (T cell leukemia homeobox 1)
Sus scrofa (pig) : TLX1 (T cell leukemia homeobox 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl10101,131,300 - 101,137,789 (+)Ensembl
GRCh3810101,130,773 - 101,137,789 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3710102,891,061 - 102,897,546 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3610102,880,252 - 102,887,536 (+)NCBINCBI36hg18NCBI36
Build 3410102,880,251 - 102,887,526NCBI
Celera1096,628,773 - 96,635,241 (+)NCBI
Cytogenetic Map10q24.31NCBI
HuRef1096,520,316 - 96,526,784 (+)NCBIHuRef
CHM1_110103,175,307 - 103,181,792 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on TLX1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1351719
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.